Dorothy Hanck to Lidocaine
This is a "connection" page, showing publications Dorothy Hanck has written about Lidocaine.
Connection Strength
2.244
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Lidocaine partially depolarizes the S4 segment in domain IV of the sodium channel. Pflugers Arch. 2011 Jan; 461(1):91-7.
Score: 0.381
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Sodium channel molecular conformations and antiarrhythmic drug affinity. Trends Cardiovasc Med. 2010 Jan; 20(1):16-21.
Score: 0.360
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Using lidocaine and benzocaine to link sodium channel molecular conformations to state-dependent antiarrhythmic drug affinity. Circ Res. 2009 Aug 28; 105(5):492-9.
Score: 0.350
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Outward stabilization of the S4 segments in domains III and IV enhances lidocaine block of sodium channels. J Physiol. 2007 Jul 01; 582(Pt 1):317-34.
Score: 0.300
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Molecular action of lidocaine on the voltage sensors of sodium channels. J Gen Physiol. 2003 Feb; 121(2):163-75.
Score: 0.223
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Lidocaine alters activation gating of cardiac Na channels. Pflugers Arch. 2000 Apr; 439(6):814-21.
Score: 0.183
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Important Role of Asparagines in Coupling the Pore and Votage-Sensor Domain in Voltage-Gated Sodium Channels. Biophys J. 2015 Dec 01; 109(11):2277-86.
Score: 0.136
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Kinetic effects of quaternary lidocaine block of cardiac sodium channels: a gating current study. J Gen Physiol. 1994 Jan; 103(1):19-43.
Score: 0.119
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Two components of use-dependent block of sodium current by lidocaine in voltage clamped cardiac Purkinje cells. J Mol Cell Cardiol. 1991 Feb; 23 Suppl 1:95-102.
Score: 0.097
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Charge at the lidocaine binding site residue Phe-1759 affects permeation in human cardiac voltage-gated sodium channels. J Physiol. 2007 Jun 01; 581(Pt 2):741-55.
Score: 0.074
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Is there a second external lidocaine binding site on mammalian cardiac cells? Am J Physiol. 1989 Jul; 257(1 Pt 2):H79-84.
Score: 0.022