Co-Authors
This is a "connection" page, showing publications co-authored by John Alverdy and Olga Y. Zaborina.
Connection Strength
9.217
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Host stress and virulence expression in intestinal pathogens: development of therapeutic strategies using mice and C. elegans. Curr Pharm Des. 2011; 17(13):1254-60.
Score: 0.380
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Structure-function aspects of PstS in multi-drug-resistant Pseudomonas aeruginosa. PLoS Pathog. 2008 Feb 08; 4(2):e43.
Score: 0.311
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Dynorphin activates quorum sensing quinolone signaling in Pseudomonas aeruginosa. PLoS Pathog. 2007 Mar; 3(3):e35.
Score: 0.291
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Identification of multi-drug resistant Pseudomonas aeruginosa clinical isolates that are highly disruptive to the intestinal epithelial barrier. Ann Clin Microbiol Antimicrob. 2006 Jun 08; 5:14.
Score: 0.277
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A Novel Nonantibiotic Gut-directed Strategy to Prevent Surgical Site Infections. Ann Surg. 2022 09 01; 276(3):472-481.
Score: 0.210
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Prevention of Anastomotic Leak Via Local Application of Tranexamic Acid to Target Bacterial-mediated Plasminogen Activation: A Practical Solution to a Complex Problem. Ann Surg. 2021 12 01; 274(6):e1038-e1046.
Score: 0.202
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Spatioregional assessment of the gut microbiota in experimental necrotizing pancreatitis. BJS Open. 2021 09 06; 5(5).
Score: 0.199
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Patient Acceptance of Routine Serial Postoperative Endoscopy Following Low Anterior Resection (LAR) and Its Ability to Detect Biomarkers in Anastomotic Lavage Fluid. World J Surg. 2021 07; 45(7):2227-2234.
Score: 0.193
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Defining Microbiome Readiness for Surgery: Dietary Prehabilitation and Stool Biomarkers as Predictive Tools to Improve Outcome. Ann Surg. 2022 11 01; 276(5):e361-e369.
Score: 0.188
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Western-type diet influences mortality from necrotising pancreatitis and demonstrates a central role for butyrate. Gut. 2021 05; 70(5):915-927.
Score: 0.186
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Spatial Compartmentalization of the Microbiome between the Lumen and Crypts Is Lost in the Murine Cecum following the Process of Surgery, Including Overnight Fasting and Exposure to Antibiotics. mSystems. 2020 Jun 09; 5(3).
Score: 0.183
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Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity. Nat Commun. 2020 05 11; 11(1):2354.
Score: 0.182
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Comparative genetics of Enterococcus faecalis intestinal tissue isolates before and after surgery in a rat model of colon anastomosis. PLoS One. 2020; 15(4):e0232165.
Score: 0.181
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Involvement of the Commensal Organism Bacillus subtilis in the Pathogenesis of Anastomotic Leak. Surg Infect (Larchmt). 2020 Dec; 21(10):865-870.
Score: 0.181
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Low-fat/high-fibre diet prehabilitation improves anastomotic healing via the microbiome: an experimental model. Br J Surg. 2020 05; 107(6):743-755.
Score: 0.177
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Western Diet Promotes Intestinal Colonization by Collagenolytic Microbes and Promotes Tumor Formation After Colorectal Surgery. Gastroenterology. 2020 03; 158(4):958-970.e2.
Score: 0.175
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Enterococcus faecalis exploits the human fibrinolytic system to drive excess collagenolysis: implications in gut healing and identification of druggable targets. Am J Physiol Gastrointest Liver Physiol. 2020 01 01; 318(1):G1-G9.
Score: 0.174
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Identification of Collagenolytic Bacteria in Human Samples: Screening Methods and Clinical Implications for Resolving and Preventing Anastomotic Leaks and Wound Complications. Dis Colon Rectum. 2019 08; 62(8):972-979.
Score: 0.172
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Mice Fed an Obesogenic Western Diet, Administered Antibiotics, and Subjected to a Sterile Surgical Procedure Develop Lethal Septicemia with Multidrug-Resistant Pathobionts. mBio. 2019 07 30; 10(4).
Score: 0.172
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Oral Polyphosphate Suppresses Bacterial Collagenase Production and Prevents Anastomotic Leak Due to Serratia marcescens and Pseudomonas aeruginosa. Ann Surg. 2018 06; 267(6):1112-1118.
Score: 0.159
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Novel de novo synthesized phosphate carrier compound ABA-PEG20k-Pi20 suppresses collagenase production in Enterococcus faecalis and prevents colonic anastomotic leak in an experimental model. Br J Surg. 2018 09; 105(10):1368-1376.
Score: 0.157
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Can Methicillin-resistant Staphylococcus aureus Silently Travel From the Gut to the Wound and Cause Postoperative Infection? Modeling the "Trojan Horse Hypothesis". Ann Surg. 2018 04; 267(4):749-758.
Score: 0.157
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Media from macrophages co-incubated with Enterococcus faecalis induces epithelial cell monolayer reassembly and altered cell morphology. PLoS One. 2017; 12(8):e0182825.
Score: 0.150
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De Novo Synthesis of Phosphorylated Triblock Copolymers with Pathogen Virulence-Suppressing Properties That Prevent Infection-Related Mortality. ACS Biomater Sci Eng. 2017 Sep 11; 3(9):2076-2085.
Score: 0.149
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Optimum Operating Room Environment for the Prevention of Surgical Site Infections. Surg Infect (Larchmt). 2017 May/Jun; 18(4):503-507.
Score: 0.147
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Modeling Acinetobacter baumannii wound infections: The critical role of iron. J Trauma Acute Care Surg. 2017 03; 82(3):557-565.
Score: 0.146
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Lack of evidence for tissue hypoxia as a contributing factor in anastomotic leak following colon anastomosis and segmental devascularization in rats. Int J Colorectal Dis. 2017 Apr; 32(4):539-547.
Score: 0.144
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Critical role of microbiota within cecal crypts on the regenerative capacity of the intestinal epithelium following surgical stress. Am J Physiol Gastrointest Liver Physiol. 2017 Feb 01; 312(2):G112-G122.
Score: 0.143
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Morphine Promotes Colonization of Anastomotic Tissues with Collagenase - Producing Enterococcus faecalis and Causes Leak. J Gastrointest Surg. 2016 10; 20(10):1744-51.
Score: 0.140
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The Shift of an Intestinal "Microbiome" to a "Pathobiome" Governs the Course and Outcome of Sepsis Following Surgical Injury. Shock. 2016 May; 45(5):475-82.
Score: 0.137
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Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak. Sci Transl Med. 2015 May 06; 7(286):286ra68.
Score: 0.128
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Pseudomonas aeruginosa wound infection involves activation of its iron acquisition system in response to fascial contact. J Trauma Acute Care Surg. 2015 Apr; 78(4):823-9.
Score: 0.127
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The opposing forces of the intestinal microbiome and the emerging pathobiome. Surg Clin North Am. 2014 Dec; 94(6):1151-61.
Score: 0.123
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Membership and behavior of ultra-low-diversity pathogen communities present in the gut of humans during prolonged critical illness. mBio. 2014 Sep 23; 5(5):e01361-14.
Score: 0.123
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Intestinal anastomotic injury alters spatially defined microbiome composition and function. Microbiome. 2014; 2:35.
Score: 0.123
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Localization of DING proteins on PstS-containing outer-surface appendages of Pseudomonas aeruginosa. FEMS Microbiol Lett. 2014 Mar; 352(1):54-61.
Score: 0.117
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Microscopic analysis: morphotypes and cellular appendages. Methods Mol Biol. 2014; 1149:99-107.
Score: 0.117
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Phosphate-containing polyethylene glycol polymers prevent lethal sepsis by multidrug-resistant pathogens. Antimicrob Agents Chemother. 2014; 58(2):966-77.
Score: 0.116
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Emergence of the P2 phenotype in Pseudomonas aeruginosa PAO1 strains involves various mutations in mexT or mexF. J Bacteriol. 2014 Jan; 196(2):504-13.
Score: 0.116
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High molecular weight polyethylene glycol (PEG 15-20) maintains mucosal microbial barrier function during intestinal graft preservation. J Surg Res. 2013 Aug; 183(2):869-75.
Score: 0.111
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Intestinal tissues induce an SNP mutation in Pseudomonas aeruginosa that enhances its virulence: possible role in anastomotic leak. PLoS One. 2012; 7(8):e44326.
Score: 0.107
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The intestinal environment of surgical injury transforms Pseudomonas aeruginosa into a discrete hypervirulent morphotype capable of causing lethal peritonitis. Surgery. 2013 Jan; 153(1):36-43.
Score: 0.106
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Novel model to study combined effects of microorganisms and oxidants on development of intestinal necrosis. Surg Infect (Larchmt). 2012 Aug; 13(4):238-44.
Score: 0.106
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Pseudomonas aeruginosa overrides the virulence inducing effect of opioids when it senses an abundance of phosphate. PLoS One. 2012; 7(4):e34883.
Score: 0.104
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Pseudomonas aeruginosa virulence expression is directly activated by morphine and is capable of causing lethal gut-derived sepsis in mice during chronic morphine administration. Ann Surg. 2012 Feb; 255(2):386-93.
Score: 0.102
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Candida albicans isolates from the gut of critically ill patients respond to phosphate limitation by expressing filaments and a lethal phenotype. PLoS One. 2012; 7(1):e30119.
Score: 0.102
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Pseudomonas aeruginosa potentiates the lethal effect of intestinal ischemia-reperfusion injury: the role of in vivo virulence activation. J Trauma. 2011 Dec; 71(6):1575-82.
Score: 0.101
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Protective effects of nonionic triblock copolymers on bile acid-mediated epithelial barrier disruption. Shock. 2011 Nov; 36(5):451-7.
Score: 0.101
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Prevention of siderophore- mediated gut-derived sepsis due to P. aeruginosa can be achieved without iron provision by maintaining local phosphate abundance: role of pH. BMC Microbiol. 2011 Sep 26; 11:212.
Score: 0.100
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The molecular Koch's postulates and surgical infection: a view forward. Surgery. 2010 Jun; 147(6):757-65.
Score: 0.091
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Oral PEG 15-20 protects the intestine against radiation: role of lipid rafts. Am J Physiol Gastrointest Liver Physiol. 2009 Dec; 297(6):G1041-52.
Score: 0.087
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Red death in Caenorhabditis elegans caused by Pseudomonas aeruginosa PAO1. Proc Natl Acad Sci U S A. 2009 Apr 14; 106(15):6327-32.
Score: 0.084
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Depletion of intestinal phosphate after operative injury activates the virulence of P aeruginosa causing lethal gut-derived sepsis. Surgery. 2008 Aug; 144(2):189-97.
Score: 0.080
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Recognition of intestinal epithelial HIF-1alpha activation by Pseudomonas aeruginosa. Am J Physiol Gastrointest Liver Physiol. 2007 Jan; 292(1):G134-42.
Score: 0.070
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Chronic acid water feeding protects mice against lethal gut-derived sepsis due to Pseudomonas aeruginosa. Curr Issues Intest Microbiol. 2006 Mar; 7(1):19-28.
Score: 0.068
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Recognition of host immune activation by Pseudomonas aeruginosa. Science. 2005 Jul 29; 309(5735):774-7.
Score: 0.065
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The impact of stress and nutrition on bacterial-host interactions at the intestinal epithelial surface. Curr Opin Clin Nutr Metab Care. 2005 Mar; 8(2):205-9.
Score: 0.063
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Surgical injury and metabolic stress enhance the virulence of the human opportunistic pathogen Pseudomonas aeruginosa. Surg Infect (Larchmt). 2005; 6(2):185-95.
Score: 0.063
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Components of intestinal epithelial hypoxia activate the virulence circuitry of Pseudomonas. Am J Physiol Gastrointest Liver Physiol. 2005 May; 288(5):G1048-54.
Score: 0.062
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The Combined Effect of Western Diet Consumption and Diclofenac Administration Alters the Gut Microbiota and Promotes Anastomotic Leakage in the Distal Colon. Biomedicines. 2024 Sep 24; 12(10).
Score: 0.061
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High-molecular-weight polyethylene glycol prevents lethal sepsis due to intestinal Pseudomonas aeruginosa. Gastroenterology. 2004 Feb; 126(2):488-98.
Score: 0.059
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Pseudomonas aeruginosa expresses a lethal virulence determinant, the PA-I lectin/adhesin, in the intestinal tract of a stressed host: the role of epithelia cell contact and molecules of the Quorum Sensing Signaling System. Ann Surg. 2003 Nov; 238(5):754-64.
Score: 0.058
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Peptide YY: A Paneth cell antimicrobial peptide that maintains Candida gut commensalism. Science. 2023 08 04; 381(6657):502-508.
Score: 0.057
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Western Diet-induced Transcriptional Changes in Anastomotic Tissue Is Associated With Early Local Recurrence in a Mouse Model of Colorectal Surgery. Ann Surg. 2023 12 01; 278(6):954-960.
Score: 0.057
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Enterococcus faecalis promotes a migratory and invasive phenotype in colon cancer cells. Neoplasia. 2022 05; 27:100787.
Score: 0.052
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Enterococcus faecalis Is Associated with Anastomotic Leak in Patients Undergoing Colorectal Surgery. Surg Infect (Larchmt). 2021 Dec; 22(10):1047-1051.
Score: 0.049
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An in vitro tissue model for screening sustained release of phosphate-based therapeutic attenuation of pathogen-induced proteolytic matrix degradation. J Mater Chem B. 2020 03 25; 8(12):2454-2465.
Score: 0.045
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Infliximab Does Not Promote the Presence of Collagenolytic Bacteria in a Mouse Model of Colorectal Anastomosis. J Gastrointest Surg. 2020 11; 24(11):2637-2642.
Score: 0.044
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Sustained Release of Phosphates From Hydrogel Nanoparticles Suppresses Bacterial Collagenase and Biofilm Formation in vitro. Front Bioeng Biotechnol. 2019; 7:153.
Score: 0.043
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De Novo Synthesis and Functional Analysis of Polyphosphate-Loaded Poly(Ethylene) Glycol Hydrogel Nanoparticles Targeting Pyocyanin and Pyoverdin Production in Pseudomonas aeruginosa as a Model Intestinal Pathogen. Ann Biomed Eng. 2017 04; 45(4):1058-1068.
Score: 0.035
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C. elegans and mutants with chronic nicotine exposure as a novel model of cancer phenotype. Cancer Biol Ther. 2016; 17(1):91-103.
Score: 0.034
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Agent-based model of epithelial host-pathogen interactions in anastomotic leak. J Surg Res. 2013 Oct; 184(2):730-8.
Score: 0.027
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Integration of TGF-ß- and EGFR-based signaling pathways using an agent-based model of epithelial restitution. Wound Repair Regen. 2012 Nov-Dec; 20(6):862-71.
Score: 0.027
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Agent-based dynamic knowledge representation of Pseudomonas aeruginosa virulence activation in the stressed gut: Towards characterizing host-pathogen interactions in gut-derived sepsis. Theor Biol Med Model. 2011 Sep 19; 8:33.
Score: 0.025
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Protective effects of high-molecular weight polyethylene glycol (PEG) in human lung endothelial cell barrier regulation: role of actin cytoskeletal rearrangement. Microvasc Res. 2009 Mar; 77(2):174-86.
Score: 0.021