James Liao to Humans
This is a "connection" page, showing publications James Liao has written about Humans.
Connection Strength
1.280
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Understanding the molecular mechanisms of statin pleiotropic effects. Arch Toxicol. 2023 06; 97(6):1529-1545.
Score: 0.030
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Emerging views of statin pleiotropy and cholesterol lowering. Cardiovasc Res. 2022 01 29; 118(2):413-423.
Score: 0.028
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Targeting Rho-associated coiled-coil forming protein kinase (ROCK) in cardiovascular fibrosis and stiffening. Expert Opin Ther Targets. 2020 01; 24(1):47-62.
Score: 0.024
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The Pleiotropic Effects of Statins - From Coronary Artery Disease and Stroke to Atrial Fibrillation and Ventricular Tachyarrhythmia. Curr Vasc Pharmacol. 2019; 17(3):222-232.
Score: 0.023
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ROCK as a therapeutic target for ischemic stroke. Expert Rev Neurother. 2017 Dec; 17(12):1167-1177.
Score: 0.021
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Tumor necrosis factor-a levels and non-surgical bleeding in continuous-flow left ventricular assist devices. J Heart Lung Transplant. 2018 01; 37(1):107-115.
Score: 0.020
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Pleiotropic Effects of Statins on the Cardiovascular System. Circ Res. 2017 Jan 06; 120(1):229-243.
Score: 0.020
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Elevated Angiopoietin-2 Level in Patients With Continuous-Flow Left Ventricular Assist Devices Leads to Altered Angiogenesis and Is Associated With Higher Nonsurgical Bleeding. Circulation. 2016 Jul 12; 134(2):141-52.
Score: 0.019
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Rho Kinases and Cardiac Remodeling. Circ J. 2016 Jun 24; 80(7):1491-8.
Score: 0.019
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Relative Lack of Culprit and Obstructive Coronary Lesions in Patients With Acute Ischemic Stroke and Elevated Cardiac Troponin. Circulation. 2016 Mar 29; 133(13):1228-9.
Score: 0.018
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The Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosis. Pharmacol Rev. 2015; 67(1):103-17.
Score: 0.017
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Evidence of pleiotropy by statins: leukocyte Rho kinase (ROCK) activity and pretreated statin before percutaneous coronary interventions are clinical vascular outcome predictors. Int J Cardiol. 2014 Sep; 176(1):250-3.
Score: 0.016
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Gene variations of ROCKs and risk of ischaemic stroke: the Women's Genome Health Study. Clin Sci (Lond). 2014 Jun; 126(12):829-835.
Score: 0.016
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Potential serum biomarkers in the pathophysiological processes of stroke. Expert Rev Neurother. 2014 Feb; 14(2):173-85.
Score: 0.016
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Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis. Antioxid Redox Signal. 2014 Mar 10; 20(8):1251-67.
Score: 0.016
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Linking endothelial dysfunction with endothelial cell activation. J Clin Invest. 2013 Feb; 123(2):540-1.
Score: 0.015
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ROCKs as immunomodulators of stroke. Expert Opin Ther Targets. 2012 Oct; 16(10):1013-25.
Score: 0.014
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Increased leukocyte Rho-associated coiled-coil containing protein kinase activity predicts the presence and severity of coronary vasospastic angina. Atherosclerosis. 2012 Apr; 221(2):521-6.
Score: 0.014
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A mouse model of diet-induced obesity and insulin resistance. Methods Mol Biol. 2012; 821:421-33.
Score: 0.014
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Mitohormesis: another pleiotropic effect of statins? Eur Heart J. 2012 Jun; 33(11):1299-301.
Score: 0.014
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Squalene synthase inhibitor lapaquistat acetate: could anything be better than statins? Circulation. 2011 May 10; 123(18):1925-8.
Score: 0.013
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Rho-associated coiled-coil-forming kinases (ROCKs): potential targets for the treatment of atherosclerosis and vascular disease. Trends Pharmacol Sci. 2011 Mar; 32(3):167-73.
Score: 0.013
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NF-?B and innate immunity in ischemic stroke. Ann N Y Acad Sci. 2010 Oct; 1207:32-40.
Score: 0.013
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Pleiotropic effects of statins. - Basic research and clinical perspectives -. Circ J. 2010 May; 74(5):818-26.
Score: 0.012
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Novel aspects of the roles of Rac1 GTPase in the cardiovascular system. Curr Opin Pharmacol. 2010 Apr; 10(2):116-21.
Score: 0.012
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Targeting eNOS and beyond: emerging heterogeneity of the role of endothelial Rho proteins in stroke protection. Expert Rev Neurother. 2009 Aug; 9(8):1171-86.
Score: 0.012
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Statins and cardiovascular diseases: from cholesterol lowering to pleiotropy. Curr Pharm Des. 2009; 15(5):467-78.
Score: 0.011
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Rho kinase: an important mediator of atherosclerosis and vascular disease. Curr Pharm Des. 2009; 15(27):3108-15.
Score: 0.011
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Increased leukocyte ROCK activity in patients after acute ischemic stroke. Brain Res. 2009 Feb 27; 1257:89-93.
Score: 0.011
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Comparison of effects of rosuvastatin (10 mg) versus atorvastatin (40 mg) on rho kinase activity in caucasian men with a previous atherosclerotic event. Am J Cardiol. 2009 Feb 15; 103(4):437-41.
Score: 0.011
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Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation. Circulation. 2009 Jan 06; 119(1):131-8.
Score: 0.011
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Increased vascular senescence and impaired endothelial progenitor cell function mediated by mutation of circadian gene Per2. Circulation. 2008 Nov 18; 118(21):2166-73.
Score: 0.011
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Fine-tuning the angiogenic response to vascular endothelial growth factor. Circ Res. 2008 Aug 01; 103(3):229-30.
Score: 0.011
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Dynamic regulation of endothelial NOS mediated by competitive interaction with alpha-actinin-4 and calmodulin. FASEB J. 2008 May; 22(5):1450-7.
Score: 0.011
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Translational therapeutics of dipyridamole. Arterioscler Thromb Vasc Biol. 2008 Mar; 28(3):s39-42.
Score: 0.011
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Pleiotropic effects of statin therapy: molecular mechanisms and clinical results. Trends Mol Med. 2008 Jan; 14(1):37-44.
Score: 0.010
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A method for measuring Rho kinase activity in tissues and cells. Methods Enzymol. 2008; 439:181-9.
Score: 0.010
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Does it matter whether or not a lipid-lowering agent inhibits Rho kinase? Curr Atheroscler Rep. 2007 Nov; 9(5):384-8.
Score: 0.010
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Rho kinase (ROCK) inhibitors. J Cardiovasc Pharmacol. 2007 Jul; 50(1):17-24.
Score: 0.010
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Increased Rho kinase activity in a Taiwanese population with metabolic syndrome. J Am Coll Cardiol. 2007 Apr 17; 49(15):1619-1624.
Score: 0.010
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Secondary prevention of stroke and transient ischemic attack: is more platelet inhibition the answer? Circulation. 2007 Mar 27; 115(12):1615-21.
Score: 0.010
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Phosphatidylinositol 3-kinase/protein kinase Akt negatively regulates plasminogen activator inhibitor type 1 expression in vascular endothelial cells. Am J Physiol Heart Circ Physiol. 2007 Apr; 292(4):H1937-42.
Score: 0.010
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Safety and efficacy of statins in Asians. Am J Cardiol. 2007 Feb 01; 99(3):410-4.
Score: 0.010
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Rapid nongenomic actions of thyroid hormone. Proc Natl Acad Sci U S A. 2006 Sep 19; 103(38):14104-9.
Score: 0.010
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Rho-kinase: a potential link between hypercholesterolemia and abnormal vascular smooth muscle contraction. Circ Res. 2006 Aug 04; 99(3):238-9.
Score: 0.010
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FHL2/SLIM3 decreases cardiomyocyte survival by inhibitory interaction with sphingosine kinase-1. Circ Res. 2006 Sep 01; 99(5):468-76.
Score: 0.010
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Absence of TRAM restricts Toll-like receptor 4 signaling in vascular endothelial cells to the MyD88 pathway. Circ Res. 2006 May 12; 98(9):1134-40.
Score: 0.009
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Physiological role of ROCKs in the cardiovascular system. Am J Physiol Cell Physiol. 2006 Mar; 290(3):C661-8.
Score: 0.009
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Rho GTPases, statins, and nitric oxide. Circ Res. 2005 Dec 09; 97(12):1232-5.
Score: 0.009
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Clinical implications for statin pleiotropy. Curr Opin Lipidol. 2005 Dec; 16(6):624-9.
Score: 0.009
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Drug Insight: statins and stroke. Nat Clin Pract Cardiovasc Med. 2005 Nov; 2(11):576-84.
Score: 0.009
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Effects of statins on 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition beyond low-density lipoprotein cholesterol. Am J Cardiol. 2005 Sep 05; 96(5A):24F-33F.
Score: 0.009
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Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection. Stroke. 2005 Oct; 36(10):2251-7.
Score: 0.009
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Rho-kinase mediates hyperglycemia-induced plasminogen activator inhibitor-1 expression in vascular endothelial cells. Circulation. 2005 Jun 21; 111(24):3261-8.
Score: 0.009
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ROCKs as therapeutic targets in cardiovascular diseases. Expert Rev Cardiovasc Ther. 2005 May; 3(3):441-51.
Score: 0.009
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Pleiotropic effects of statins. Annu Rev Pharmacol Toxicol. 2005; 45:89-118.
Score: 0.009
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Induction of angiogenesis by heat shock protein 90 mediated by protein kinase Akt and endothelial nitric oxide synthase. Arterioscler Thromb Vasc Biol. 2004 Dec; 24(12):2238-44.
Score: 0.008
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Statins: potent vascular anti-inflammatory agents. Int J Clin Pract Suppl. 2004 Oct; (143):41-8.
Score: 0.008
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Inhibition of Rho-kinase leads to rapid activation of phosphatidylinositol 3-kinase/protein kinase Akt and cardiovascular protection. Arterioscler Thromb Vasc Biol. 2004 Oct; 24(10):1842-7.
Score: 0.008
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Statins and myocardial hypertrophy. Coron Artery Dis. 2004 Aug; 15(5):247-50.
Score: 0.008
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Statin therapy: having the good without the bad. Hypertension. 2004 Jun; 43(6):1171-2.
Score: 0.008
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Statin therapy for cardiac hypertrophy and heart failure. J Investig Med. 2004 May; 52(4):248-53.
Score: 0.008
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Lipid management with statins. The lower the better? Z Kardiol. 2004 Jan; 93(1):4-9.
Score: 0.008
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Inhibition of MHC II gene transcription by nitric oxide and antioxidants. Curr Pharm Des. 2004; 10(8):893-8.
Score: 0.008
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11,12-epoxyeicosatrienoic acid (11,12-EET): structural determinants for inhibition of TNF-alpha-induced VCAM-1 expression. Bioorg Med Chem Lett. 2003 Nov 17; 13(22):4011-4.
Score: 0.008
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Isoprenoid metabolism and the pleiotropic effects of statins. Curr Atheroscler Rep. 2003 Sep; 5(5):372-8.
Score: 0.008
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Activation of the phosphatidylinositol 3-kinase/protein kinase Akt pathway mediates nitric oxide-induced endothelial cell migration and angiogenesis. Mol Cell Biol. 2003 Aug; 23(16):5726-37.
Score: 0.008
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Short-term statin therapy improves cardiac function and symptoms in patients with idiopathic dilated cardiomyopathy. Circulation. 2003 Aug 19; 108(7):839-43.
Score: 0.008
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Nontranscriptional actions of the glucocorticoid receptor. J Mol Med (Berl). 2003 Mar; 81(3):168-74.
Score: 0.008
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Role of statin pleiotropism in acute coronary syndromes and stroke. Int J Clin Pract Suppl. 2003 Mar; (134):51-7.
Score: 0.008
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Endothelium-dependent effects of statins. Arterioscler Thromb Vasc Biol. 2003 May 01; 23(5):729-36.
Score: 0.008
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Cross-coupling between the oestrogen receptor and phosphoinositide 3-kinase. Biochem Soc Trans. 2003 Feb; 31(Pt 1):66-70.
Score: 0.007
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Rapid effects of statins: from prophylaxis to therapy for ischemic stroke. Arterioscler Thromb Vasc Biol. 2003 Feb 01; 23(2):156-7.
Score: 0.007
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Molecular basis of cell membrane estrogen receptor interaction with phosphatidylinositol 3-kinase in endothelial cells. Arterioscler Thromb Vasc Biol. 2003 Feb 01; 23(2):198-203.
Score: 0.007
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A novel pleiotropic effect of statins: prevention of cardiac hypertrophy by cholesterol-independent mechanisms. Ann Med. 2003; 35(6):398-403.
Score: 0.007
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Nonnuclear actions of estrogen. Arterioscler Thromb Vasc Biol. 2002 Dec 01; 22(12):1952-61.
Score: 0.007
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Beyond lipid lowering: the role of statins in vascular protection. Int J Cardiol. 2002 Nov; 86(1):5-18.
Score: 0.007
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Functional interaction of endothelial nitric oxide synthase with a voltage-dependent anion channel. Proc Natl Acad Sci U S A. 2002 Oct 01; 99(20):13108-13.
Score: 0.007
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Isoprenoids as mediators of the biological effects of statins. J Clin Invest. 2002 Aug; 110(3):285-8.
Score: 0.007
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Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase. Circulation. 2002 Jul 02; 106(1):57-62.
Score: 0.007
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Non-nuclear actions of estrogen: new targets for prevention and treatment of cardiovascular disease. Mol Interv. 2002 Jul; 2(4):219-28.
Score: 0.007
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Inhibition of vascular smooth muscle cell migration by cytochrome p450 epoxygenase-derived eicosanoids. Circ Res. 2002 May 17; 90(9):1020-7.
Score: 0.007
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Inhibition of major histocompatibility complex class II gene transcription by nitric oxide and antioxidants. J Biol Chem. 2002 Jul 19; 277(29):26460-7.
Score: 0.007
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Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase. Nat Med. 2002 May; 8(5):473-9.
Score: 0.007
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Statins and ischemic stroke. Atheroscler Suppl. 2002 May; 3(1):21-5.
Score: 0.007
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Nongenomic mechanisms of endothelial nitric oxide synthase activation by the selective estrogen receptor modulator raloxifene. Circulation. 2002 Mar 19; 105(11):1368-73.
Score: 0.007
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Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors. Arterioscler Thromb Vasc Biol. 2001 Nov; 21(11):1712-9.
Score: 0.007
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Salicylates and vascular smooth muscle cell proliferation: molecular mechanisms for cell cycle arrest. Trends Cardiovasc Med. 2001 Nov; 11(8):339-44.
Score: 0.007
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Challenging Statin Pleiotropy: Preeclampsia. Circulation. 2021 08 31; 144(9):680-683.
Score: 0.007
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Increase in Blood-Brain Barrier (BBB) Permeability Is Regulated by MMP3 via the ERK Signaling Pathway. Oxid Med Cell Longev. 2021; 2021:6655122.
Score: 0.007
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Activation of Galpha s mediates induction of tissue-type plasminogen activator gene transcription by epoxyeicosatrienoic acids. J Biol Chem. 2001 May 11; 276(19):15983-9.
Score: 0.007
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SALAD-BAAR: A numerical risk score for hospital admission or emergency department presentation in ambulatory patients with cardiovascular disease. Clin Cardiol. 2021 Feb; 44(2):193-199.
Score: 0.007
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Inhibition of vascular smooth muscle cell proliferation by sodium salicylate mediated by upregulation of p21(Waf1) and p27(Kip1). Circulation. 2000 Oct 24; 102(17):2124-30.
Score: 0.006
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Targeting Rho in cardiovascular disease. Circ Res. 2000 Sep 29; 87(7):526-8.
Score: 0.006
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Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature. 2000 Sep 28; 407(6803):538-41.
Score: 0.006
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Community Health Workers Reduce Rehospitalizations and Emergency Department Visits for Low-Socioeconomic Urban Patients With Heart Failure. Crit Pathw Cardiol. 2020 09; 19(3):139-145.
Score: 0.006
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Direct vascular effects of HMG-CoA reductase inhibitors. Trends Cardiovasc Med. 2000 May; 10(4):143-8.
Score: 0.006
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A functional role of I kappa B-epsilon in endothelial cell activation. J Immunol. 2000 Mar 15; 164(6):3316-22.
Score: 0.006
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Atorvastatin Treatment of Cavernous Angiomas with Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) Trial. Neurosurgery. 2019 12 01; 85(6):843-853.
Score: 0.006
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Association of Rising Violent Crime With Blood Pressure and Cardiovascular Risk: Longitudinal Evidence From Chicago, 2014-2016. Am J Hypertens. 2019 11 15; 32(12):1192-1198.
Score: 0.006
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Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids. Science. 1999 Aug 20; 285(5431):1276-9.
Score: 0.006
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3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing rho GTPase-induced down-regulation of p27(Kip1). J Biol Chem. 1999 Jul 30; 274(31):21926-31.
Score: 0.006
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Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study. J Hypertens. 2019 05; 37(5):1083-1095.
Score: 0.006
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Activation of guanine nucleotide-binding proteins and induction of endothelial tissue-type plasminogen activator gene transcription by alcohol. J Biol Chem. 1999 Apr 23; 274(17):12055-60.
Score: 0.006
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Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase. J Biol Chem. 1998 Sep 11; 273(37):24266-71.
Score: 0.006
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Inducible nitric oxide: an autoregulatory feedback inhibitor of vascular inflammation. J Immunol. 1998 Aug 15; 161(4):1970-6.
Score: 0.005
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Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase. Proc Natl Acad Sci U S A. 1998 Jul 21; 95(15):8880-5.
Score: 0.005
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The Rho Kinase Isoforms ROCK1 and ROCK2 Each Contribute to the Development of Experimental Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2018 04; 58(4):471-481.
Score: 0.005
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Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors. Circulation. 1998 Mar 31; 97(12):1129-35.
Score: 0.005
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Inhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated down-regulation of endothelial nitric oxide synthase. J Biol Chem. 1997 Dec 12; 272(50):31725-9.
Score: 0.005
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Inhibition of endothelial vascular cell adhesion molecule-1 expression by nitric oxide involves the induction and nuclear translocation of IkappaBalpha. J Biol Chem. 1997 Dec 05; 272(49):30969-74.
Score: 0.005
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Hydrogen peroxide-mediated transcriptional induction of macrophage colony-stimulating factor by TGF-beta1. J Immunol. 1997 Sep 01; 159(5):2418-23.
Score: 0.005
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Cardiology Consultation in the Emergency Department Reduces Re-hospitalizations for Low-Socioeconomic Patients with Acute Decompensated Heart Failure. Am J Med. 2017 09; 130(9):1112.e17-1112.e31.
Score: 0.005
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Unique fractal evaluation and therapeutic implications of mitochondrial morphology in malignant mesothelioma. Sci Rep. 2016 Apr 15; 6:24578.
Score: 0.005
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Peripheral plasma vitamin D and non-HDL cholesterol reflect the severity of cerebral cavernous malformation disease. Biomark Med. 2016; 10(3):255-64.
Score: 0.005
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Rho-associated kinase activity is an independent predictor of cardiovascular events in acute coronary syndrome. Hypertension. 2015 Oct; 66(4):892-9.
Score: 0.004
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ROCK insufficiency attenuates ozone-induced airway hyperresponsiveness in mice. Am J Physiol Lung Cell Mol Physiol. 2015 Oct 01; 309(7):L736-46.
Score: 0.004
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Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J Clin Invest. 1995 Jul; 96(1):60-8.
Score: 0.004
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MnTBAP stimulates angiogenic functions in endothelial cells through mitofusin-1. Vascul Pharmacol. 2015 Sep; 72:163-71.
Score: 0.004
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Exogenous nitric oxide inhibits Rho-associated kinase activity in patients with angina pectoris: a randomized controlled trial. Hypertens Res. 2015 Jul; 38(7):485-90.
Score: 0.004
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Effect of aldosterone-producing adenoma on endothelial function and Rho-associated kinase activity in patients with primary aldosteronism. Hypertension. 2015 Apr; 65(4):841-8.
Score: 0.004
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Two functional polymorphisms of ROCK2 enhance arterial stiffening through inhibiting its activity and expression. J Mol Cell Cardiol. 2015 Feb; 79:180-6.
Score: 0.004
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Critical role of exogenous nitric oxide in ROCK activity in vascular smooth muscle cells. PLoS One. 2014; 9(10):e109017.
Score: 0.004
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Rho-associated kinase activity is a predictor of cardiovascular outcomes. Hypertension. 2014 Apr; 63(4):856-64.
Score: 0.004
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Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation. Arterioscler Thromb Vasc Biol. 2013 Jul; 33(7):1591-600.
Score: 0.004
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Elevated rho-kinase activity as a marker indicating atherosclerosis and inflammation burden in polyvascular disease patients with concomitant coronary and peripheral arterial disease. Clin Cardiol. 2013 Jun; 36(6):347-51.
Score: 0.004
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Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion. PLoS One. 2012; 7(11):e47842.
Score: 0.004
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A combination of increased Rho kinase activity and N-terminal pro-B-type natriuretic peptide predicts worse cardiovascular outcome in patients with acute coronary syndrome. Int J Cardiol. 2013 Sep 10; 167(6):2813-9.
Score: 0.004
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Increased Rho kinase activity in congestive heart failure. Eur J Heart Fail. 2012 Sep; 14(9):965-73.
Score: 0.004
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Mineralocorticoid receptor blocker eplerenone improves endothelial function and inhibits Rho-associated kinase activity in patients with hypertension. Clin Pharmacol Ther. 2012 Feb; 91(2):289-97.
Score: 0.003
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Acute myocardial infarction after ergonovine administration for uterine bleeding. Am J Cardiol. 1991 Sep 15; 68(8):823-4.
Score: 0.003
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Rho-associated kinase activity, endothelial function, and cardiovascular risk factors. Arterioscler Thromb Vasc Biol. 2011 Oct; 31(10):2353-9.
Score: 0.003
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Differential impairment of vasodilator responsiveness of peripheral resistance and conduit vessels in humans with atherosclerosis. Circ Res. 1991 Apr; 68(4):1027-34.
Score: 0.003
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Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis. Hum Mol Genet. 2011 Jun 15; 20(12):2344-55.
Score: 0.003
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Pitavastatin-induced angiogenesis and arteriogenesis is mediated by Notch1 in a murine hindlimb ischemia model without induction of VEGF. Lab Invest. 2011 May; 91(5):691-703.
Score: 0.003
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Calcium channel blocker and Rho-associated kinase activity in patients with hypertension. J Hypertens. 2011 Feb; 29(2):373-9.
Score: 0.003
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Elevated homocysteine and C-reactive protein levels independently predict worsening prognosis after stroke in Chinese patients. J Huazhong Univ Sci Technolog Med Sci. 2010 Oct; 30(5):643-7.
Score: 0.003
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Measurement of Rho-associated kinase (ROCK) activity in humans: validity of leukocyte p-MBS/t-MBS in comparison with vascular response to fasudil. Atherosclerosis. 2011 Jan; 214(1):117-21.
Score: 0.003
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Rho-kinase inhibition: a novel therapeutic target for the treatment of cardiovascular diseases. Drug Discov Today. 2010 Aug; 15(15-16):622-9.
Score: 0.003
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RhoA/ROCK signaling is essential for multiple aspects of VEGF-mediated angiogenesis. FASEB J. 2010 Sep; 24(9):3186-95.
Score: 0.003
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Increased leukocyte rho kinase (ROCK) activity and endothelial dysfunction in cigarette smokers. Hypertens Res. 2010 Apr; 33(4):354-9.
Score: 0.003
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Statins inhibit Rho kinase activity in patients with atherosclerosis. Atherosclerosis. 2009 Aug; 205(2):517-21.
Score: 0.003
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Identification of ROCK1 as an upstream activator of the JIP-3 to JNK signaling axis in response to UVB damage. Sci Signal. 2008 Nov 25; 1(47):ra14.
Score: 0.003
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Tumor necrosis factor-alpha downregulates endothelial nitric oxide synthase mRNA stability via translation elongation factor 1-alpha 1. Circ Res. 2008 Sep 12; 103(6):591-7.
Score: 0.003
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Linking Notch signaling to ischemic stroke. Proc Natl Acad Sci U S A. 2008 Mar 25; 105(12):4856-61.
Score: 0.003
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Roles of rho-associated kinase and oxidative stress in the pathogenesis of aortic stiffness. J Am Coll Cardiol. 2007 Feb 13; 49(6):698-705.
Score: 0.002
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Rho kinase inhibition improves endothelial function in human subjects with coronary artery disease. Circ Res. 2006 Dec 08; 99(12):1426-32.
Score: 0.002
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Simvastatin decreases IL-6 and IL-8 production in epithelial cells. J Dent Res. 2006 Jun; 85(6):520-3.
Score: 0.002
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Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2. Circulation. 2004 Oct 12; 110(15):2132-6.
Score: 0.002
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Atorvastatin restores endothelial function in normocholesterolemic smokers independent of changes in low-density lipoprotein. Circ Res. 2004 Jul 23; 95(2):217-23.
Score: 0.002
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Statin therapy is associated with improved patency of autogenous infrainguinal bypass grafts. J Vasc Surg. 2004 Jun; 39(6):1178-85.
Score: 0.002
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Targeting eNOS for stroke protection. Trends Neurosci. 2004 May; 27(5):283-9.
Score: 0.002
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Long-term statin use and psychological well-being. J Am Coll Cardiol. 2003 Aug 20; 42(4):690-7.
Score: 0.002
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Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids. J Clin Invest. 2002 Dec; 110(11):1729-38.
Score: 0.002
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Estrogens and glucocorticoids inhibit endothelial vascular cell adhesion molecule-1 expression by different transcriptional mechanisms. Circ Res. 2000 Jul 07; 87(1):19-25.
Score: 0.002
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VEGF increases retinal vascular ICAM-1 expression in vivo. Invest Ophthalmol Vis Sci. 1999 Jul; 40(8):1808-12.
Score: 0.001
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Inflammatory cytokines and oxidized low density lipoproteins increase endothelial cell expression of membrane type 1-matrix metalloproteinase. J Biol Chem. 1999 Apr 23; 274(17):11924-9.
Score: 0.001
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[Regulation of endothelial NO production by Rho GTPase]. Med Klin (Munich). 1999 Apr 15; 94(4):211-8.
Score: 0.001
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Differential regulation of endothelial cell adhesion molecule expression by nitric oxide donors and antioxidants. J Leukoc Biol. 1998 Jun; 63(6):732-9.
Score: 0.001
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[New findings on the action of HMG-CoA-reductase inhibitors]. Dtsch Med Wochenschr. 1997 Oct 10; 122(41):1255-9.
Score: 0.001