Eric C. Beyer to Eye Proteins
This is a "connection" page, showing publications Eric C. Beyer has written about Eye Proteins.
Connection Strength
3.675
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The Cataract-linked Mutant Connexin50D47A Causes Endoplasmic Reticulum Stress in Mouse Lenses. J Biol Chem. 2016 08 19; 291(34):17569-78.
Score: 0.522
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Connexin50D47A decreases levels of fiber cell connexins and impairs lens fiber cell differentiation. Invest Ophthalmol Vis Sci. 2013 Nov 19; 54(12):7614-22.
Score: 0.437
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The GJA8 allele encoding CX50I247M is a rare polymorphism, not a cataract-causing mutation. Mol Vis. 2009 Sep 14; 15:1881-5.
Score: 0.327
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Cataracts are caused by alterations of a critical N-terminal positive charge in connexin50. Invest Ophthalmol Vis Sci. 2008 Jun; 49(6):2549-56.
Score: 0.294
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Transgenic overexpression of connexin50 induces cataracts. Exp Eye Res. 2007 Mar; 84(3):513-28.
Score: 0.271
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Loss of function and impaired degradation of a cataract-associated mutant connexin50. Eur J Cell Biol. 2003 May; 82(5):209-21.
Score: 0.210
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Heteromeric connexons formed by the lens connexins, connexin43 and connexin56. Eur J Cell Biol. 2001 Jan; 80(1):11-9.
Score: 0.179
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Cultured chicken embryo lens cells resemble differentiating fiber cells in vivo and contain two kinetic pools of connexin56. Exp Eye Res. 1999 Apr; 68(4):475-84.
Score: 0.158
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Distinct behavior of connexin56 and connexin46 gap junctional channels can be predicted from the behavior of their hemi-gap-junctional channels. Biophys J. 1995 May; 68(5):1796-803.
Score: 0.121
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Characterization of the gap junction protein connexin56 in the chicken lens by immunofluorescence and immunoblotting. Invest Ophthalmol Vis Sci. 1994 Nov; 35(12):4109-17.
Score: 0.117
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A connexin50 mutant, CX50fs, that causes cataracts is unstable, but is rescued by a proteasomal inhibitor. J Biol Chem. 2013 Jul 12; 288(28):20427-34.
Score: 0.105
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Chick connexin-56, a novel lens gap junction protein. Molecular cloning and functional expression. J Biol Chem. 1993 Jan 05; 268(1):706-12.
Score: 0.103
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An MIP/AQP0 mutation with impaired trafficking and function underlies an autosomal dominant congenital lamellar cataract. Exp Eye Res. 2013 May; 110:136-41.
Score: 0.101
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Autophagy: a pathway that contributes to connexin degradation. J Cell Sci. 2011 Mar 15; 124(Pt 6):910-20.
Score: 0.091
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Different consequences of cataract-associated mutations at adjacent positions in the first extracellular boundary of connexin50. Am J Physiol Cell Physiol. 2011 May; 300(5):C1055-64.
Score: 0.090
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A mutant connexin50 with enhanced hemichannel function leads to cell death. Invest Ophthalmol Vis Sci. 2009 Dec; 50(12):5837-45.
Score: 0.081
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The cytoplasmic accumulations of the cataract-associated mutant, Connexin50P88S, are long-lived and form in the endoplasmic reticulum. Exp Eye Res. 2009 Mar; 88(3):600-9.
Score: 0.077
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A novel connexin50 mutation associated with congenital nuclear pulverulent cataracts. J Med Genet. 2008 Mar; 45(3):155-60.
Score: 0.072
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A novel GJA8 mutation is associated with autosomal dominant lamellar pulverulent cataract: further evidence for gap junction dysfunction in human cataract. J Med Genet. 2006 Jan; 43(1):e2.
Score: 0.063
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Functional role of the carboxyl terminal domain of human connexin 50 in gap junctional channels. J Membr Biol. 2002 Mar 15; 186(2):101-12.
Score: 0.049
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Cataract-linked serine mutations in the gap junction protein connexin50 expose a sorting signal that promotes its lysosomal degradation. J Biol Chem. 2022 03; 298(3):101673.
Score: 0.048
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Molecular mechanisms underlying enhanced hemichannel function of a cataract-associated Cx50 mutant. Biophys J. 2021 12 21; 120(24):5644-5656.
Score: 0.047
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Molecular mechanism underlying a Cx50-linked congenital cataract. Am J Physiol. 1999 06; 276(6):C1443-6.
Score: 0.040
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The gap-junction protein connexin 56 is phosphorylated in the intracellular loop and the carboxy-terminal region. Eur J Biochem. 1997 Feb 15; 244(1):89-97.
Score: 0.034
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Differential expression of two gap junction proteins in corneal epithelium. Eur J Cell Biol. 1994 Jun; 64(1):95-100.
Score: 0.028
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Co-expression of lens fiber connexins modifies hemi-gap-junctional channel behavior. Biophys J. 1999 Jan; 76(1 Pt 1):198-206.
Score: 0.010