The University of Chicago Header Logo

Connection

Yoav Gilad to Humans

This is a "connection" page, showing publications Yoav Gilad has written about Humans.
Connection Strength

1.091
  1. The Baboon as a Model to Study Human Health and Complex Disease. Am J Primatol. 2026 Sep; 88(9):e70207.
    View in: PubMed
    Score: 0.031
  2. Beyond the baseline: mapping the context-specific regulatory landscape of disease. Trends Genet. 2026 04; 42(4):324-338.
    View in: PubMed
    Score: 0.030
  3. Oxygen-induced stress reveals context-specific gene regulatory effects in human brain organoids. Genome Res. 2025 08 01; 35(8):1689-1700.
    View in: PubMed
    Score: 0.029
  4. Cell type and dynamic state govern genetic regulation of gene expression in heterogeneous differentiating cultures. Cell Genom. 2024 12 11; 4(12):100701.
    View in: PubMed
    Score: 0.028
  5. Induced Pluripotent Stem Cells in Disease Biology and the Evidence for Their In Vitro Utility. Annu Rev Genet. 2023 11 27; 57:341-360.
    View in: PubMed
    Score: 0.025
  6. The relationship between regulatory changes in cis and trans and the evolution of gene expression in humans and chimpanzees. Genome Biol. 2023 09 11; 24(1):207.
    View in: PubMed
    Score: 0.025
  7. Human embryoid bodies as a novel system for genomic studies of functionally diverse cell types. Elife. 2022 02 10; 11.
    View in: PubMed
    Score: 0.023
  8. Divergence in alternative polyadenylation contributes to gene regulatory differences between humans and chimpanzees. Elife. 2021 02 17; 10.
    View in: PubMed
    Score: 0.021
  9. Dynamic effects of genetic variation on gene expression revealed following hypoxic stress in cardiomyocytes. Elife. 2021 02 08; 10.
    View in: PubMed
    Score: 0.021
  10. A TAD Skeptic: Is 3D Genome Topology Conserved? Trends Genet. 2021 03; 37(3):216-223.
    View in: PubMed
    Score: 0.021
  11. Gene expression variability in human and chimpanzee populations share common determinants. Elife. 2020 10 21; 9.
    View in: PubMed
    Score: 0.021
  12. Where Are the Disease-Associated eQTLs? Trends Genet. 2021 02; 37(2):109-124.
    View in: PubMed
    Score: 0.021
  13. Effective study design for comparative functional genomics. Nat Rev Genet. 2020 07; 21(7):385-386.
    View in: PubMed
    Score: 0.020
  14. Prime time for primate functional genomics. Curr Opin Genet Dev. 2020 06; 62:1-7.
    View in: PubMed
    Score: 0.020
  15. Characterizing and inferring quantitative cell cycle phase in single-cell RNA-seq data analysis. Genome Res. 2020 04; 30(4):611-621.
    View in: PubMed
    Score: 0.020
  16. A comparison of gene expression and DNA methylation patterns across tissues and species. Genome Res. 2020 02; 30(2):250-262.
    View in: PubMed
    Score: 0.020
  17. Reorganization of 3D genome structure may contribute to gene regulatory evolution in primates. PLoS Genet. 2019 07; 15(7):e1008278.
    View in: PubMed
    Score: 0.019
  18. Dynamic genetic regulation of gene expression during cellular differentiation. Science. 2019 06 28; 364(6447):1287-1290.
    View in: PubMed
    Score: 0.019
  19. Discovery and characterization of variance QTLs in human induced pluripotent stem cells. PLoS Genet. 2019 04; 15(4):e1008045.
    View in: PubMed
    Score: 0.019
  20. A generally conserved response to hypoxia in iPSC-derived cardiomyocytes from humans and chimpanzees. Elife. 2019 04 08; 8.
    View in: PubMed
    Score: 0.019
  21. A Comparative Assessment of Human and Chimpanzee iPSC-derived Cardiomyocytes with Primary Heart Tissues. Sci Rep. 2018 10 17; 8(1):15312.
    View in: PubMed
    Score: 0.018
  22. A Methodological Assessment and Characterization of Genetically-Driven Variation in Three Human Phosphoproteomes. Sci Rep. 2018 08 14; 8(1):12106.
    View in: PubMed
    Score: 0.018
  23. Determining the genetic basis of anthracycline-cardiotoxicity by molecular response QTL mapping in induced cardiomyocytes. Elife. 2018 05 08; 7.
    View in: PubMed
    Score: 0.017
  24. Silencing of transposable elements may not be a major driver of regulatory evolution in primate iPSCs. Elife. 2018 04 12; 7.
    View in: PubMed
    Score: 0.017
  25. Impact of regulatory variation across human iPSCs and differentiated cells. Genome Res. 2018 01; 28(1):122-131.
    View in: PubMed
    Score: 0.017
  26. Human genomics: Cracking the regulatory code. Nature. 2017 10 11; 550(7675):190-191.
    View in: PubMed
    Score: 0.017
  27. Batch effects and the effective design of single-cell gene expression studies. Sci Rep. 2017 01 03; 7:39921.
    View in: PubMed
    Score: 0.016
  28. Genetic Variation, Not Cell Type of Origin, Underlies the Majority of Identifiable Regulatory Differences in iPSCs. PLoS Genet. 2016 Jan; 12(1):e1005793.
    View in: PubMed
    Score: 0.015
  29. Synthesis, biological studies and molecular dynamics of new anticancer RGD-based peptide conjugates for targeted drug delivery. Bioorg Med Chem. 2016 Jan 15; 24(2):294-303.
    View in: PubMed
    Score: 0.015
  30. Genome-Wide Association Studies of the Human Gut Microbiota. PLoS One. 2015; 10(11):e0140301.
    View in: PubMed
    Score: 0.015
  31. Reprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression Signature. PLoS Genet. 2015 May; 11(5):e1005216.
    View in: PubMed
    Score: 0.014
  32. The genetic and mechanistic basis for variation in gene regulation. PLoS Genet. 2015 Jan; 11(1):e1004857.
    View in: PubMed
    Score: 0.014
  33. Genomic variation. Impact of regulatory variation from RNA to protein. Science. 2015 Feb 06; 347(6222):664-7.
    View in: PubMed
    Score: 0.014
  34. Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels. PLoS Genet. 2014 Sep; 10(9):e1004663.
    View in: PubMed
    Score: 0.014
  35. Comparative studies of gene regulatory mechanisms. Curr Opin Genet Dev. 2014 Dec; 29:68-74.
    View in: PubMed
    Score: 0.014
  36. Comparative metabolomics in primates reveals the effects of diet and gene regulatory variation on metabolic divergence. Sci Rep. 2014 Jul 28; 4:5809.
    View in: PubMed
    Score: 0.013
  37. RNA-seq: impact of RNA degradation on transcript quantification. BMC Biol. 2014 May 30; 12:42.
    View in: PubMed
    Score: 0.013
  38. Seasonal variation in human gut microbiome composition. PLoS One. 2014; 9(3):e90731.
    View in: PubMed
    Score: 0.013
  39. The functional consequences of variation in transcription factor binding. PLoS Genet. 2014 Mar; 10(3):e1004226.
    View in: PubMed
    Score: 0.013
  40. Does a unique olfactory genome imply a unique olfactory world? Nat Neurosci. 2014 Jan; 17(1):6-8.
    View in: PubMed
    Score: 0.013
  41. Epigenetic modifications are associated with inter-species gene expression variation in primates. Genome Biol. 2014; 15(12):547.
    View in: PubMed
    Score: 0.013
  42. Primate transcript and protein expression levels evolve under compensatory selection pressures. Science. 2013 Nov 29; 342(6162):1100-4.
    View in: PubMed
    Score: 0.013
  43. Social environmental effects on gene regulation. Cell Mol Life Sci. 2013 Nov; 70(22):4323-39.
    View in: PubMed
    Score: 0.012
  44. The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels. PLoS Genet. 2012; 8(10):e1003000.
    View in: PubMed
    Score: 0.012
  45. The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes. Hum Mol Genet. 2012 May 01; 21(9):2111-23.
    View in: PubMed
    Score: 0.011
  46. Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection. Proc Natl Acad Sci U S A. 2012 Jan 24; 109(4):1204-9.
    View in: PubMed
    Score: 0.011
  47. Using genomic tools to study regulatory evolution. Methods Mol Biol. 2012; 856:335-61.
    View in: PubMed
    Score: 0.011
  48. A genome-wide study of DNA methylation patterns and gene expression levels in multiple human and chimpanzee tissues. PLoS Genet. 2011 Feb; 7(2):e1001316.
    View in: PubMed
    Score: 0.011
  49. Gene expression differences among primates are associated with changes in a histone epigenetic modification. Genetics. 2011 Apr; 187(4):1225-34.
    View in: PubMed
    Score: 0.011
  50. The effects of EBV transformation on gene expression levels and methylation profiles. Hum Mol Genet. 2011 Apr 15; 20(8):1643-52.
    View in: PubMed
    Score: 0.011
  51. Functional comparison of innate immune signaling pathways in primates. PLoS Genet. 2010 Dec 16; 6(12):e1001249.
    View in: PubMed
    Score: 0.010
  52. Sex-specific and lineage-specific alternative splicing in primates. Genome Res. 2010 Feb; 20(2):180-9.
    View in: PubMed
    Score: 0.010
  53. Characterizing natural variation using next-generation sequencing technologies. Trends Genet. 2009 Oct; 25(10):463-71.
    View in: PubMed
    Score: 0.010
  54. Expression quantitative trait loci detected in cell lines are often present in primary tissues. Hum Mol Genet. 2009 Nov 15; 18(22):4296-303.
    View in: PubMed
    Score: 0.010
  55. Sex-specific genetic architecture of human disease. Nat Rev Genet. 2008 Dec; 9(12):911-22.
    View in: PubMed
    Score: 0.009
  56. Gene regulation in primates evolves under tissue-specific selection pressures. PLoS Genet. 2008 Nov; 4(11):e1000271.
    View in: PubMed
    Score: 0.009
  57. Revealing the architecture of gene regulation: the promise of eQTL studies. Trends Genet. 2008 Aug; 24(8):408-15.
    View in: PubMed
    Score: 0.009
  58. Generation of an induced pluripotent stem cell line CGOi001-A from a patient with hereditary thrombocytopenia and a germline ANKRD26 mutation. Stem Cell Res. 2026 Mar; 91:103919.
    View in: PubMed
    Score: 0.007
  59. Single-cell sequencing reveals lineage-specific dynamic genetic regulation of gene expression during human cardiomyocyte differentiation. PLoS Genet. 2022 01; 18(1):e1009666.
    View in: PubMed
    Score: 0.006
  60. Benchmarking sequencing methods and tools that facilitate the study of alternative polyadenylation. Genome Biol. 2021 10 14; 22(1):291.
    View in: PubMed
    Score: 0.006
  61. Functional dynamic genetic effects on gene regulation are specific to particular cell types and environmental conditions. Elife. 2021 05 14; 10.
    View in: PubMed
    Score: 0.005
  62. Alternative polyadenylation mediates genetic regulation of gene expression. Elife. 2020 06 25; 9.
    View in: PubMed
    Score: 0.005
  63. Systematic Comparison of High-throughput Single-Cell and Single-Nucleus Transcriptomes during Cardiomyocyte Differentiation. Sci Rep. 2020 01 30; 10(1):1535.
    View in: PubMed
    Score: 0.005
  64. A comparative study of endoderm differentiation in humans and chimpanzees. Genome Biol. 2018 10 15; 19(1):162.
    View in: PubMed
    Score: 0.005
  65. Predicting susceptibility to tuberculosis based on gene expression profiling in dendritic cells. Sci Rep. 2017 07 18; 7(1):5702.
    View in: PubMed
    Score: 0.004
  66. Reducing mitochondrial reads in ATAC-seq using CRISPR/Cas9. Sci Rep. 2017 05 26; 7(1):2451.
    View in: PubMed
    Score: 0.004
  67. Host genetic variation in mucosal immunity pathways influences the upper airway microbiome. Microbiome. 2017 02 01; 5(1):16.
    View in: PubMed
    Score: 0.004
  68. Gene expression in local stroma reflects breast tumor states and predicts patient outcome. Sci Rep. 2016 12 16; 6:39240.
    View in: PubMed
    Score: 0.004
  69. DNA methylation in lung cells is associated with asthma endotypes and genetic risk. JCI Insight. 2016 12 08; 1(20):e90151.
    View in: PubMed
    Score: 0.004
  70. The human olfactory transcriptome. BMC Genomics. 2016 08 11; 17(1):619.
    View in: PubMed
    Score: 0.004
  71. Thousands of novel translated open reading frames in humans inferred by ribosome footprint profiling. Elife. 2016 05 27; 5.
    View in: PubMed
    Score: 0.004
  72. RNA splicing is a primary link between genetic variation and disease. Science. 2016 Apr 29; 352(6285):600-4.
    View in: PubMed
    Score: 0.004
  73. Integrated analyses of gene expression and genetic association studies in a founder population. Hum Mol Genet. 2016 05 15; 25(10):2104-2112.
    View in: PubMed
    Score: 0.004
  74. Mycobacterial infection induces a specific human innate immune response. Sci Rep. 2015 Nov 20; 5:16882.
    View in: PubMed
    Score: 0.004
  75. msCentipede: Modeling Heterogeneity across Genomic Sites and Replicates Improves Accuracy in the Inference of Transcription Factor Binding. PLoS One. 2015; 10(9):e0138030.
    View in: PubMed
    Score: 0.004
  76. Bacterial infection remodels the DNA methylation landscape of human dendritic cells. Genome Res. 2015 Dec; 25(12):1801-11.
    View in: PubMed
    Score: 0.004
  77. WASP: allele-specific software for robust molecular quantitative trait locus discovery. Nat Methods. 2015 Nov; 12(11):1061-3.
    View in: PubMed
    Score: 0.004
  78. Metastasis Suppressors Regulate the Tumor Microenvironment by Blocking Recruitment of Prometastatic Tumor-Associated Macrophages. Cancer Res. 2015 Oct 01; 75(19):4063-73.
    View in: PubMed
    Score: 0.004
  79. A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics. Elife. 2015 Jun 23; 4:e07103.
    View in: PubMed
    Score: 0.004
  80. Host genetic variation influences gene expression response to rhinovirus infection. PLoS Genet. 2015 Apr; 11(4):e1005111.
    View in: PubMed
    Score: 0.004
  81. The effect of freeze-thaw cycles on gene expression levels in lymphoblastoid cell lines. PLoS One. 2014; 9(9):e107166.
    View in: PubMed
    Score: 0.003
  82. Co-binding by YY1 identifies the transcriptionally active, highly conserved set of CTCF-bound regions in primate genomes. Genome Biol. 2013 Dec 31; 14(12):R148.
    View in: PubMed
    Score: 0.003
  83. Identification of genetic variants that affect histone modifications in human cells. Science. 2013 Nov 08; 342(6159):747-9.
    View in: PubMed
    Score: 0.003
  84. Controls of nucleosome positioning in the human genome. PLoS Genet. 2012; 8(11):e1003036.
    View in: PubMed
    Score: 0.003
  85. General olfactory sensitivity database (GOSdb): candidate genes and their genomic variations. Hum Mutat. 2013 Jan; 34(1):32-41.
    View in: PubMed
    Score: 0.003
  86. Genomics: ENCODE explained. Nature. 2012 Sep 06; 489(7414):52-5.
    View in: PubMed
    Score: 0.003
  87. Regulatory element copy number differences shape primate expression profiles. Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31):12656-61.
    View in: PubMed
    Score: 0.003
  88. Comment on "Widespread RNA and DNA sequence differences in the human transcriptome". Science. 2012 Mar 16; 335(6074):1302; author reply 1302.
    View in: PubMed
    Score: 0.003
  89. Time-dependent transcriptional profiling links gene expression to mitogen-activated protein kinase kinase 4 (MKK4)-mediated suppression of omental metastatic colonization. Clin Exp Metastasis. 2012 Jun; 29(5):397-408.
    View in: PubMed
    Score: 0.003
  90. Exon-specific QTLs skew the inferred distribution of expression QTLs detected using gene expression array data. PLoS One. 2012; 7(2):e30629.
    View in: PubMed
    Score: 0.003
  91. DNase?I sensitivity QTLs are a major determinant of human expression variation. Nature. 2012 Feb 05; 482(7385):390-4.
    View in: PubMed
    Score: 0.003
  92. Dissecting the regulatory architecture of gene expression QTLs. Genome Biol. 2012 Jan 31; 13(1):R7.
    View in: PubMed
    Score: 0.003
  93. Comparative RNA sequencing reveals substantial genetic variation in endangered primates. Genome Res. 2012 Apr; 22(4):602-10.
    View in: PubMed
    Score: 0.003
  94. A genome sequence resource for the aye-aye (Daubentonia madagascariensis), a nocturnal lemur from Madagascar. Genome Biol Evol. 2012; 4(2):126-35.
    View in: PubMed
    Score: 0.003
  95. False positive peaks in ChIP-seq and other sequencing-based functional assays caused by unannotated high copy number regions. Bioinformatics. 2011 Aug 01; 27(15):2144-6.
    View in: PubMed
    Score: 0.003
  96. DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines. Genome Biol. 2011; 12(1):R10.
    View in: PubMed
    Score: 0.003
  97. Noisy splicing drives mRNA isoform diversity in human cells. PLoS Genet. 2010 Dec 09; 6(12):e1001236.
    View in: PubMed
    Score: 0.003
  98. Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data. Genome Res. 2011 Mar; 21(3):447-55.
    View in: PubMed
    Score: 0.003
  99. Understanding mechanisms underlying human gene expression variation with RNA sequencing. Nature. 2010 Apr 01; 464(7289):768-72.
    View in: PubMed
    Score: 0.002
  100. Effect of read-mapping biases on detecting allele-specific expression from RNA-sequencing data. Bioinformatics. 2009 Dec 15; 25(24):3207-12.
    View in: PubMed
    Score: 0.002
  101. High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet. 2008 Oct; 4(10):e1000214.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.