Louis Philipson to Islets of Langerhans
This is a "connection" page, showing publications Louis Philipson has written about Islets of Langerhans.
Connection Strength
5.158
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Pancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational Analysis. PLoS One. 2016; 11(5):e0152869.
Score: 0.432
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Glucose sensing in the pancreatic beta cell: a computational systems analysis. Theor Biol Med Model. 2010 May 24; 7:15.
Score: 0.286
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Action potentials and insulin secretion: new insights into the role of Kv channels. Diabetes Obes Metab. 2007 Nov; 9 Suppl 2:89-98.
Score: 0.240
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Modulation of the pancreatic islet beta-cell-delayed rectifier potassium channel Kv2.1 by the polyunsaturated fatty acid arachidonate. J Biol Chem. 2007 Mar 09; 282(10):7442-9.
Score: 0.226
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Downstream regulatory element antagonistic modulator regulates islet prodynorphin expression. Am J Physiol Endocrinol Metab. 2006 Sep; 291(3):E587-95.
Score: 0.215
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Inositol (1,4,5)-trisphosphate dynamics and intracellular calcium oscillations in pancreatic beta-cells. Diabetes. 2005 Nov; 54(11):3073-81.
Score: 0.209
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Delayed-rectifier (KV2.1) regulation of pancreatic beta-cell calcium responses to glucose: inhibitor specificity and modeling. Am J Physiol Endocrinol Metab. 2005 Oct; 289(4):E578-85.
Score: 0.204
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5-amino-imidazole carboxamide riboside acutely potentiates glucose-stimulated insulin secretion from mouse pancreatic islets by KATP channel-dependent and -independent pathways. Biochem Biophys Res Commun. 2005 May 20; 330(4):1073-9.
Score: 0.202
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FRET-based voltage probes for confocal imaging: membrane potential oscillations throughout pancreatic islets. Am J Physiol Cell Physiol. 2005 Jul; 289(1):C224-9.
Score: 0.199
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Does the glucose-dependent insulin secretion mechanism itself cause oxidative stress in pancreatic beta-cells? Diabetes. 2004 Aug; 53(8):1942-8.
Score: 0.191
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Direct imaging shows that insulin granule exocytosis occurs by complete vesicle fusion. Proc Natl Acad Sci U S A. 2004 Jun 22; 101(25):9266-71.
Score: 0.190
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Small-conductance calcium-activated K+ channels are expressed in pancreatic islets and regulate glucose responses. Diabetes. 2003 Aug; 52(8):2000-6.
Score: 0.178
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Modeling of Ca2+ flux in pancreatic beta-cells: role of the plasma membrane and intracellular stores. Am J Physiol Endocrinol Metab. 2003 Jul; 285(1):E138-54.
Score: 0.174
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Visualizing superoxide production in normal and diabetic rat islets of Langerhans. J Biol Chem. 2003 Mar 14; 278(11):9796-801.
Score: 0.172
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TRP genes: candidates for nonselective cation channels and store-operated channels in insulin-secreting cells. Diabetes. 2002 Feb; 51 Suppl 1:S183-9.
Score: 0.161
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Baculovirus-mediated gene transfer into pancreatic islet cells. Diabetes. 2000 Dec; 49(12):1986-91.
Score: 0.148
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Integrated Pancreatic Blood Flow: Bidirectional Microcirculation Between Endocrine and Exocrine Pancreas. Diabetes. 2020 07; 69(7):1439-1450.
Score: 0.141
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Beta-cell ion channels: keys to endodermal excitability. Horm Metab Res. 1999 Aug; 31(8):455-61.
Score: 0.135
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Comparative evaluation of simple indices using a single fasting blood sample to estimate beta cell function after islet transplantation. Am J Transplant. 2018 04; 18(4):990-997.
Score: 0.122
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Expression and function of pancreatic beta-cell delayed rectifier K+ channels. Role in stimulus-secretion coupling. J Biol Chem. 1996 Dec 13; 271(50):32241-6.
Score: 0.113
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K+ channels: generating excitement in pancreatic beta-cells. Diabetes. 1996 Jul; 45(7):845-53.
Score: 0.109
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The Brain-to-Pancreatic Islet Neuronal Map Reveals Differential Glucose Regulation From Distinct Hypothalamic Regions. Diabetes. 2016 09; 65(9):2711-23.
Score: 0.108
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Pas de deux or more: the sulfonylurea receptor and K+ channels. Science. 1995 Apr 21; 268(5209):372-3.
Score: 0.101
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Delayed rectifier K+ channel overexpression in transgenic islets and beta-cells associated with impaired glucose responsiveness. J Biol Chem. 1994 Nov 11; 269(45):27787-90.
Score: 0.098
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Human, rodent, and canine pancreatic beta-cells express a sodium channel alpha 1-subunit related to a fetal brain isoform. Diabetes. 1993 Sep; 42(9):1372-7.
Score: 0.090
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Sequence and functional expression in Xenopus oocytes of a human insulinoma and islet potassium channel. Proc Natl Acad Sci U S A. 1991 Jan 01; 88(1):53-7.
Score: 0.075
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Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature. 2010 Jul 29; 466(7306):627-31.
Score: 0.072
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Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice. Am J Physiol Endocrinol Metab. 2008 Feb; 294(2):E217-29.
Score: 0.059
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Kv2.1 ablation alters glucose-induced islet electrical activity, enhancing insulin secretion. Cell Metab. 2007 Sep; 6(3):229-35.
Score: 0.059
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Improved outcomes in islet isolation and transplantation by the use of a novel hemoglobin-based O2 carrier. Am J Transplant. 2006 Dec; 6(12):2861-70.
Score: 0.056
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Intragranular targeting of syncollin, but not a syncollinGFP chimera, inhibits regulated insulin exocytosis in pancreatic beta-cells. J Endocrinol. 2005 Apr; 185(1):57-67.
Score: 0.050
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Islet isolation under cGMP conditions: replacing the coil. Transplant Proc. 2004 May; 36(4):1031-3.
Score: 0.047
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Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism. Diabetes. 2001 Nov; 50(11):2472-80.
Score: 0.040
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Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion. Am J Physiol Endocrinol Metab. 2000 Feb; 278(2):E340-51.
Score: 0.035
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Defective pancreatic beta-cell glycolytic signaling in hepatocyte nuclear factor-1alpha-deficient mice. J Biol Chem. 1998 Sep 18; 273(38):24457-64.
Score: 0.032
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Characterization of a Ca2+ release-activated nonselective cation current regulating membrane potential and [Ca2+]i oscillations in transgenically derived beta-cells. J Biol Chem. 1998 Apr 24; 273(17):10402-10.
Score: 0.031
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Apoptosis in insulin-secreting cells. Evidence for the role of intracellular Ca2+ stores and arachidonic acid metabolism. J Clin Invest. 1998 Apr 15; 101(8):1623-32.
Score: 0.031
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NIDDM is associated with loss of pancreatic beta-cell L-type Ca2+ channel activity. Am J Physiol. 1996 Jan; 270(1 Pt 1):E133-40.
Score: 0.026
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TCF1 links GIPR signaling to the control of beta cell function and survival. Nat Med. 2016 Jan; 22(1):84-90.
Score: 0.026
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Defective glucose-dependent endoplasmic reticulum Ca2+ sequestration in diabetic mouse islets of Langerhans. J Biol Chem. 1994 Jul 15; 269(28):18279-82.
Score: 0.024
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Dependence on NADH produced during glycolysis for beta-cell glucose signaling. J Biol Chem. 1994 Apr 15; 269(15):10979-82.
Score: 0.023
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The chemistrode: a droplet-based microfluidic device for stimulation and recording with high temporal, spatial, and chemical resolution. Proc Natl Acad Sci U S A. 2008 Nov 04; 105(44):16843-8.
Score: 0.016
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Insulin secretory deficiency and glucose intolerance in Rab3A null mice. J Biol Chem. 2003 Mar 14; 278(11):9715-21.
Score: 0.011