The University of Chicago Header Logo

Connection

Issam Awad to Cerebral Hemorrhage

Back to Details
This is a "connection" page, showing publications Issam Awad has written about Cerebral Hemorrhage.
Issam Awad
Connection Strength
14.939
Cerebral Hemorrhage
  1. Identifying features of prior hemorrhage in cerebral cavernous malformations on quantitative susceptibility maps: a machine learning pilot study. J Neurosurg. 2025 Dec 01; 143(6):1567-1574.
    View in: PubMed
    Score: 0.722
  2. A Systematic Review of MicroRNAs in Hemorrhagic Neurovascular Disease: Cerebral Cavernous Malformations as a Paradigm. Int J Mol Sci. 2025 Apr 17; 26(8).
    View in: PubMed
    Score: 0.712
  3. Safety and efficacy of atorvastatin for rebleeding in cerebral cavernous malformations (AT CASH EPOC): a phase 1/2a, randomised placebo-controlled trial. Lancet Neurol. 2025 Apr; 24(4):295-304.
    View in: PubMed
    Score: 0.709
  4. Circulating molecules reflect imaging biomarkers of hemorrhage in cerebral cavernous malformations. J Cereb Blood Flow Metab. 2025 Jun; 45(6):1153-1165.
    View in: PubMed
    Score: 0.700
  5. Intracerebral Hemorrhage: Keep It Simple. Stroke. 2024 12; 55(12):2942-2945.
    View in: PubMed
    Score: 0.689
  6. In Reply: Intracerebral Hemorrhage Volume Reduction and Timing of Intervention Versus Functional Benefit and Survival in the MISTIE III and STICH Trials. Neurosurgery. 2021 09 15; 89(4):E247-E248.
    View in: PubMed
    Score: 0.555
  7. Post-Trial Enhanced Deployment and Technical Performance with the MISTIE Procedure per Lessons Learned. J Stroke Cerebrovasc Dis. 2021 Sep; 30(9):105996.
    View in: PubMed
    Score: 0.549
  8. A Roadmap for Developing Plasma Diagnostic and Prognostic Biomarkers of Cerebral Cavernous Angioma With Symptomatic Hemorrhage (CASH). Neurosurgery. 2021 02 16; 88(3):686-697.
    View in: PubMed
    Score: 0.533
  9. In Reply: Surgical Performance Determines Functional Outcome Benefit in the Minimally Invasive Surgery Plus Recombinant Tissue Plasminogen Activator for Intracerebral Hemorrhage Evacuation (MISTIE) Procedure. Neurosurgery. 2020 04 01; 86(4):E411.
    View in: PubMed
    Score: 0.502
  10. Surgery for intracerebral haemorrhage - Authors' reply. Lancet. 2019 08 24; 394(10199):e22-e23.
    View in: PubMed
    Score: 0.481
  11. Surgical Performance in Minimally Invasive Surgery Plus Recombinant Tissue Plasminogen Activator for Intracerebral Hemorrhage Evacuation Phase III Clinical Trial. Neurosurgery. 2017 Nov 01; 81(5):860-866.
    View in: PubMed
    Score: 0.424
  12. Plasma Biomarkers of Inflammation Reflect Seizures and Hemorrhagic Activity of Cerebral Cavernous Malformations. Transl Stroke Res. 2018 02; 9(1):34-43.
    View in: PubMed
    Score: 0.418
  13. Quantitative susceptibility mapping as a monitoring biomarker in cerebral cavernous malformations with recent hemorrhage. J Magn Reson Imaging. 2018 04; 47(4):1133-1138.
    View in: PubMed
    Score: 0.418
  14. Spontaneous intracerebral and intraventricular hemorrhage: advances in minimally invasive surgery and thrombolytic evacuation, and lessons learned in recent trials. Neurosurgery. 2014 Feb; 74 Suppl 1:S142-50.
    View in: PubMed
    Score: 0.327
  15. Thrombolytic evacuation of intracerebral and intraventricular hemorrhage. Curr Cardiol Rep. 2012 Dec; 14(6):754-60.
    View in: PubMed
    Score: 0.302
  16. Ventricular catheter location and the clearance of intraventricular hemorrhage. Neurosurgery. 2012 May; 70(5):1258-63; discussion 1263-4.
    View in: PubMed
    Score: 0.290
  17. External ventricular drainage for intraventricular hemorrhage. Curr Neurol Neurosci Rep. 2012 Feb; 12(1):24-33.
    View in: PubMed
    Score: 0.285
  18. Outcome predictors and spectrum of treatment eligibility with prospective protocolized management of intracerebral hemorrhage. Neurosurgery. 2009 Mar; 64(3):436-45; discussion 445-6.
    View in: PubMed
    Score: 0.233
  19. Intracerebral haemorrhage laterality and associations with mood and pain: a MISTIE III substudy. Stroke Vasc Neurol. 2025 Dec 23; 10(6):734-742.
    View in: PubMed
    Score: 0.187
  20. Impact of Minimally Invasive Surgery on Midline Shift and Outcomes in Large Supratentorial Spontaneous Intracerebral Hemorrhage: Post Hoc Analysis of MISTIE III. Neurocrit Care. 2026 Feb; 44(1):261-272.
    View in: PubMed
    Score: 0.183
  21. Does stereotactic thrombolysis with alteplase for intracerebral haemorrhage alter intraventricular haematoma volume? A secondary analysis of the MISTIE-III trial. J Neurol Neurosurg Psychiatry. 2024 Sep 17; 95(10):892-898.
    View in: PubMed
    Score: 0.171
  22. Cerebral small vessel disease modifies outcomes after minimally invasive surgery for intracerebral haemorrhage. Stroke Vasc Neurol. 2024 08 27; 9(4):446-456.
    View in: PubMed
    Score: 0.170
  23. Trial Readiness of Cavernous Malformations With Symptomatic Hemorrhage, Part II: Biomarkers and Trial Modeling. Stroke. 2024 01; 55(1):31-39.
    View in: PubMed
    Score: 0.162
  24. Mechanistic Evaluation of Diffusion Weighted Hyperintense Lesions After Large Spontaneous Intracerebral Hemorrhage: A Subgroup Analysis of MISTIE III. Neurocrit Care. 2024 Jun; 40(3):1140-1150.
    View in: PubMed
    Score: 0.162
  25. Minimally Invasive Surgery With Thrombolysis for Intracerebral Hemorrhage Evacuation: Bayesian Reanalysis of a Randomized Controlled Trial. Neurology. 2023 10 17; 101(16):e1614-e1622.
    View in: PubMed
    Score: 0.159
  26. Intraventricular Hemorrhage Expansion in the CLEAR III Trial: A Post Hoc Exploratory Analysis. Stroke. 2022 06; 53(6):1847-1853.
    View in: PubMed
    Score: 0.142
  27. Association Between Intraventricular Alteplase Use and Parenchymal Hematoma Volume in Patients With Spontaneous Intracerebral Hemorrhage and Intraventricular Hemorrhage. JAMA Netw Open. 2021 12 01; 4(12):e2135773.
    View in: PubMed
    Score: 0.141
  28. Baseline Characteristics of Patients With Cavernous Angiomas With Symptomatic Hemorrhage in Multisite Trial Readiness Project. Stroke. 2021 12; 52(12):3829-3838.
    View in: PubMed
    Score: 0.139
  29. Post-Stroke Depression in Patients with Large Spontaneous Intracerebral Hemorrhage. J Stroke Cerebrovasc Dis. 2021 Nov; 30(11):106082.
    View in: PubMed
    Score: 0.139
  30. CSF and serum inflammatory response and association with outcomes in spontaneous intracerebral hemorrhage with intraventricular extension: an analysis of the CLEAR-III Trial. J Neuroinflammation. 2021 Aug 21; 18(1):179.
    View in: PubMed
    Score: 0.138
  31. Intracerebral Hemorrhage Volume Reduction and Timing of Intervention Versus Functional Benefit and Survival in the MISTIE III and STICH Trials. Neurosurgery. 2021 04 15; 88(5):961-970.
    View in: PubMed
    Score: 0.135
  32. Leukocyte dynamics after intracerebral hemorrhage in a living patient reveal rapid adaptations to tissue milieu. JCI Insight. 2021 03 22; 6(6).
    View in: PubMed
    Score: 0.134
  33. Longitudinal transcriptomics define the stages of myeloid activation in the living human brain after intracerebral hemorrhage. Sci Immunol. 2021 02 19; 6(56).
    View in: PubMed
    Score: 0.133
  34. Temporal Evolution and Outcomes of Non-Traumatic Intracerebral Hemorrhage in Hospitalized Patients. J Stroke Cerebrovasc Dis. 2021 Mar; 30(3):105584.
    View in: PubMed
    Score: 0.132
  35. A Pooled Analysis of Diffusion-Weighted Imaging Lesions in Patients With Acute Intracerebral Hemorrhage. JAMA Neurol. 2020 Nov 01; 77(11):1390-1397.
    View in: PubMed
    Score: 0.131
  36. 3D Deep Neural Network Segmentation of Intracerebral Hemorrhage: Development and Validation for Clinical Trials. Neuroinformatics. 2021 07; 19(3):403-415.
    View in: PubMed
    Score: 0.130
  37. Role of Temporal Sequence in Treating Intracerebral Hemorrhage. Ann Neurol. 2020 08; 88(2):237-238.
    View in: PubMed
    Score: 0.128
  38. Stereotactic computed tomographic-guided aspiration and thrombolysis of intracerebral hematoma : protocol and preliminary experience. Stroke. 2000 Apr; 31(4):834-40.
    View in: PubMed
    Score: 0.125
  39. Atorvastatin Treatment of Cavernous Angiomas with Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) Trial. Neurosurgery. 2019 12 01; 85(6):843-853.
    View in: PubMed
    Score: 0.123
  40. A randomized 500-subject open-label phase 3 clinical trial of minimally invasive surgery plus alteplase in intracerebral hemorrhage evacuation (MISTIE III). Int J Stroke. 2019 07; 14(5):548-554.
    View in: PubMed
    Score: 0.117
  41. Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial. Lancet. 2019 Mar 09; 393(10175):1021-1032.
    View in: PubMed
    Score: 0.116
  42. Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice. Blood. 2019 01 17; 133(3):193-204.
    View in: PubMed
    Score: 0.114
  43. Surgery for intracerebral hemorrhage. Neurology. 1998 Sep; 51(3 Suppl 3):S69-73.
    View in: PubMed
    Score: 0.112
  44. The Incidence of Catheter Tract Hemorrhage and Catheter Placement Accuracy in the CLEAR III Trial. Neurocrit Care. 2018 08; 29(1):23-32.
    View in: PubMed
    Score: 0.112
  45. CSF inflammatory response after intraventricular hemorrhage. Neurology. 2017 Oct 10; 89(15):1553-1560.
    View in: PubMed
    Score: 0.105
  46. Permanent CSF shunting after intraventricular hemorrhage in the CLEAR III trial. Neurology. 2017 Jul 25; 89(4):355-362.
    View in: PubMed
    Score: 0.104
  47. Safety and efficacy of minimally invasive surgery plus alteplase in intracerebral haemorrhage evacuation (MISTIE): a randomised, controlled, open-label, phase 2 trial. Lancet Neurol. 2016 Nov; 15(12):1228-1237.
    View in: PubMed
    Score: 0.099
  48. Accuracy of the ABC/2 Score for Intracerebral Hemorrhage: Systematic Review and Analysis of MISTIE, CLEAR-IVH, and CLEAR III. Stroke. 2015 Sep; 46(9):2470-6.
    View in: PubMed
    Score: 0.091
  49. Bleeding and infection with external ventricular drainage: a systematic review in comparison with adjudicated adverse events in the ongoing Clot Lysis Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III (CLEAR-III IHV) trial. Neurosurgery. 2015 Mar; 76(3):291-300; discussion 301.
    View in: PubMed
    Score: 0.088
  50. Determinants of external ventricular drain placement and associated outcomes in patients with spontaneous intraventricular hemorrhage. Neurocrit Care. 2014 Dec; 21(3):426-34.
    View in: PubMed
    Score: 0.087
  51. A multicenter, randomized, double-blinded, placebo-controlled phase III study of Clot Lysis Evaluation of Accelerated Resolution of Intraventricular Hemorrhage (CLEAR III). Int J Stroke. 2014 Jun; 9(4):536-42.
    View in: PubMed
    Score: 0.079
  52. Hemorrhagic stroke: introduction. Stroke. 2013 Jun; 44(6 Suppl 1):S65-6.
    View in: PubMed
    Score: 0.078
  53. Surgical trials in intracerebral hemorrhage. Stroke. 2013 Jun; 44(6 Suppl 1):S79-82.
    View in: PubMed
    Score: 0.078
  54. Comparison of the clinical presentation of symptomatic arteriovenous malformations (angiographically visualized) and occult vascular malformations. Neurosurgery. 1993 May; 32(5):876-8.
    View in: PubMed
    Score: 0.078
  55. Minimally invasive surgery plus recombinant tissue-type plasminogen activator for intracerebral hemorrhage evacuation decreases perihematomal edema. Stroke. 2013 Mar; 44(3):627-34.
    View in: PubMed
    Score: 0.076
  56. The Modified Graeb Score: an enhanced tool for intraventricular hemorrhage measurement and prediction of functional outcome. Stroke. 2013 Mar; 44(3):635-41.
    View in: PubMed
    Score: 0.076
  57. Intensive care management of acute hemorrhagic leukoencephalitis with favorable neurologic outcome. Cleve Clin J Med. 1992 Sep-Oct; 59(5):549-52.
    View in: PubMed
    Score: 0.074
  58. Drainage efficiency with dual versus single catheters in severe intraventricular hemorrhage. Neurocrit Care. 2012 Jun; 16(3):399-405.
    View in: PubMed
    Score: 0.073
  59. Occurrence and impact of intracranial pressure elevation during treatment of severe intraventricular hemorrhage. Crit Care Med. 2012 May; 40(5):1601-8.
    View in: PubMed
    Score: 0.072
  60. Resolution of intraventricular hemorrhage varies by ventricular region and dose of intraventricular thrombolytic: the Clot Lysis: Evaluating Accelerated Resolution of IVH (CLEAR IVH) program. Stroke. 2012 Jun; 43(6):1666-8.
    View in: PubMed
    Score: 0.072
  61. Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation disease. Stroke. 2012 Feb; 43(2):571-4.
    View in: PubMed
    Score: 0.070
  62. Low-dose recombinant tissue-type plasminogen activator enhances clot resolution in brain hemorrhage: the intraventricular hemorrhage thrombolysis trial. Stroke. 2011 Nov; 42(11):3009-16.
    View in: PubMed
    Score: 0.069
  63. Intraventricular hemorrhage secondary to intranidal aneurysm rupture-successful management by arteriovenous malformation embolization followed by intraventricular tissue plasminogen activator: case report. Neurosurgery. 2011 Feb; 68(2):E581-6; discussion E586.
    View in: PubMed
    Score: 0.066
  64. Hemorrhage from cavernous malformations of the brain: definition and reporting standards. Angioma Alliance Scientific Advisory Board. Stroke. 2008 Dec; 39(12):3222-30.
    View in: PubMed
    Score: 0.057
  65. Preliminary report of the clot lysis evaluating accelerated resolution of intraventricular hemorrhage (CLEAR-IVH) clinical trial. Acta Neurochir Suppl. 2008; 105:217-20.
    View in: PubMed
    Score: 0.054
  66. Current updates in perioperative management of intracerebral hemorrhage. Neurol Clin. 2006 Nov; 24(4):745-64.
    View in: PubMed
    Score: 0.049
  67. Cerebral cavernous malformations and epilepsy. Neurosurg Focus. 2006 Jul 15; 21(1):e7.
    View in: PubMed
    Score: 0.048
  68. [Etiologic spectrum of intracerebral hemorrhage in young patients]. Neurochirurgie. 2006 Jun; 52(2-3 Pt 1):105-9.
    View in: PubMed
    Score: 0.048
  69. Pathologic features of brain hemorrhage after radiation treatment: case series with somatic mutation analysis. J Stroke Cerebrovasc Dis. 2024 Jul; 33(7):107699.
    View in: PubMed
    Score: 0.041
  70. Association Between Hematoma Volume and Risk of Subsequent Ischemic Stroke: A MISTIE III and ATACH-2 Analysis. Stroke. 2024 03; 55(3):541-547.
    View in: PubMed
    Score: 0.041
  71. Catheter Tract Hemorrhages and Intracerebral Hemorrhage Outcomes in the Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Trial. Neurosurgery. 2024 02 01; 94(2):334-339.
    View in: PubMed
    Score: 0.040
  72. One-Year Outcome Trajectories and Factors Associated with Functional Recovery Among Survivors of Intracerebral and Intraventricular Hemorrhage With Initial Severe Disability. JAMA Neurol. 2022 09 01; 79(9):856-868.
    View in: PubMed
    Score: 0.037
  73. Association of Intraventricular Fibrinolysis With Clinical Outcomes in Intracerebral Hemorrhage: An Individual Participant Data Meta-Analysis. Stroke. 2022 09; 53(9):2876-2886.
    View in: PubMed
    Score: 0.036
  74. Bayesian deep learning outperforms clinical trial estimators of intracerebral and intraventricular hemorrhage volume. J Neuroimaging. 2022 09; 32(5):968-976.
    View in: PubMed
    Score: 0.036
  75. Cerebral Hemorrhage: Pathophysiology, Treatment, and Future Directions. Circ Res. 2022 04 15; 130(8):1204-1229.
    View in: PubMed
    Score: 0.036
  76. Cerebral Microbleeds and Acute Hematoma Characteristics in the ATACH-2 and MISTIE III Trials. Neurology. 2022 03 08; 98(10):e1013-e1020.
    View in: PubMed
    Score: 0.035
  77. A quality-of-life instrument for young hemorrhagic stroke patients. Stroke. 2001 Mar; 32(3):687-95.
    View in: PubMed
    Score: 0.033
  78. Thrombolysis for Evacuation of Intracerebral and Intraventricular Hemorrhage: A Guide to Surgical Protocols With Practical Lessons Learned From the MISTIE and CLEAR Trials. Oper Neurosurg (Hagerstown). 2020 12 15; 20(1):98-108.
    View in: PubMed
    Score: 0.033
  79. Relationship of White Matter Lesions with Intracerebral Hemorrhage Expansion and Functional Outcome: MISTIE II and CLEAR III. Neurocrit Care. 2020 10; 33(2):516-524.
    View in: PubMed
    Score: 0.032
  80. Primary intraventricular hemorrhage outcomes in the CLEAR III trial. Int J Stroke. 2020 10; 15(8):872-880.
    View in: PubMed
    Score: 0.031
  81. Hemorrhagic lesion at the tentorial incisura in a patient with facial nevus. Neurosurgery. 1999 Nov; 45(5):1216-21.
    View in: PubMed
    Score: 0.030
  82. A comparison of the clinical profile of cavernous malformations with and without associated venous malformations. Neurosurgery. 1999 Jan; 44(1):41-6; discussion 46-7.
    View in: PubMed
    Score: 0.029
  83. Protocols and critical pathways for stroke care. Clin Neurosurg. 1999; 45:86-100.
    View in: PubMed
    Score: 0.029
  84. Plasma Biomarkers of Inflammation and Angiogenesis Predict Cerebral Cavernous Malformation Symptomatic Hemorrhage or Lesional Growth. Circ Res. 2018 06 08; 122(12):1716-1721.
    View in: PubMed
    Score: 0.027
  85. Intracranial cavernous malformations: lesion behavior and management strategies. Neurosurgery. 1995 Oct; 37(4):591-605.
    View in: PubMed
    Score: 0.023
  86. Radiosurgery and venous malformations. J Neurosurg. 1994 Jan; 80(1):171-3; author reply 174-5.
    View in: PubMed
    Score: 0.020
  87. Mixed vascular malformations of the brain: clinical and pathogenetic considerations. Neurosurgery. 1993 Aug; 33(2):179-88; discussion 188.
    View in: PubMed
    Score: 0.020
  88. Intracranial dural arteriovenous malformations: factors predisposing to an aggressive neurological course. J Neurosurg. 1990 Jun; 72(6):839-50.
    View in: PubMed
    Score: 0.016
  89. Reporting terminology for brain arteriovenous malformation clinical and radiographic features for use in clinical trials. Stroke. 2001 Jun; 32(6):1430-42.
    View in: PubMed
    Score: 0.008
  90. Advances in the genetics of cerebrovascular disease and stroke. Neurology. 2001 Apr 24; 56(8):997-1008.
    View in: PubMed
    Score: 0.008
  91. Parenchymal perianeurysmal cystic changes in the brain: report of five cases. Radiology. 2000 Apr; 215(1):229-33.
    View in: PubMed
    Score: 0.008
  92. Factors predisposing to clinical disability in patients with cavernous malformations of the brain. Neurosurgery. 1993 May; 32(5):730-5; discussion 735-6.
    View in: PubMed
    Score: 0.005
  93. Natural history of the cavernous angioma. J Neurosurg. 1991 Nov; 75(5):709-14.
    View in: PubMed
    Score: 0.004
  94. Proton magnetic resonance imaging in ischemic cerebrovascular disease. Ann Neurol. 1986 Oct; 20(4):502-7.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.