Wei-Jen Tang to Bacterial Toxins
This is a "connection" page, showing publications Wei-Jen Tang has written about Bacterial Toxins.
Connection Strength
2.967
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Rapid Discovery and Characterization of Synthetic Neutralizing Antibodies against Anthrax Edema Toxin. Biochemistry. 2019 07 09; 58(27):2996-3004.
Score: 0.629
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Different Roles of N-Terminal and C-Terminal Domains in Calmodulin for Activation of Bacillus anthracis Edema Factor. Toxins (Basel). 2015 Jul 13; 7(7):2598-614.
Score: 0.479
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The adenylyl cyclase activity of anthrax edema factor. Mol Aspects Med. 2009 Dec; 30(6):423-30.
Score: 0.315
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An extended conformation of calmodulin induces interactions between the structural domains of adenylyl cyclase from Bacillus anthracis to promote catalysis. J Biol Chem. 2000 Nov 17; 275(46):36334-40.
Score: 0.174
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Inhibition of the adenylyl cyclase toxin, edema factor, from Bacillus anthracis by a series of 18 mono- and bis-(M)ANT-substituted nucleoside 5'-triphosphates. Naunyn Schmiedebergs Arch Pharmacol. 2012 Jan; 385(1):57-68.
Score: 0.092
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Noninvasive imaging technologies reveal edema toxin as a key virulence factor in anthrax. Am J Pathol. 2011 Jun; 178(6):2523-35.
Score: 0.090
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Distinct interactions of 2'- and 3'-O-(N-methyl)anthraniloyl-isomers of ATP and GTP with the adenylyl cyclase toxin of Bacillus anthracis, edema factor. Biochem Pharmacol. 2009 Aug 01; 78(3):224-30.
Score: 0.079
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Cellular functions and X-ray structure of anthrolysin O, a cholesterol-dependent cytolysin secreted by Bacillus anthracis. J Biol Chem. 2009 May 22; 284(21):14645-56.
Score: 0.077
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Molecular analysis of the interaction of anthrax adenylyl cyclase toxin, edema factor, with 2'(3')-O-(N-(methyl)anthraniloyl)-substituted purine and pyrimidine nucleotides. Mol Pharmacol. 2009 Mar; 75(3):693-703.
Score: 0.076
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Protein-protein docking and analysis reveal that two homologous bacterial adenylyl cyclase toxins interact with calmodulin differently. J Biol Chem. 2008 Aug 29; 283(35):23836-45.
Score: 0.074
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Anthrax toxin-induced shock in rats is associated with pulmonary edema and hemorrhage. Microb Pathog. 2008 Jun; 44(6):467-72.
Score: 0.071
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Anthrax toxins induce shock in rats by depressed cardiac ventricular function. PLoS One. 2007 May 23; 2(5):e466.
Score: 0.068
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Lethal and edema toxins of anthrax induce distinct hemodynamic dysfunction. Front Biosci. 2007 May 01; 12:4670-5.
Score: 0.068
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Anthrax edema toxin sensitizes DBA/2J mice to lethal toxin. Infect Immun. 2007 May; 75(5):2120-5.
Score: 0.067
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Bacillus anthracis edema toxin causes extensive tissue lesions and rapid lethality in mice. Am J Pathol. 2005 Nov; 167(5):1309-20.
Score: 0.061
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Anthrax edema toxin cooperates with lethal toxin to impair cytokine secretion during infection of dendritic cells. J Immunol. 2005 Apr 15; 174(8):4934-41.
Score: 0.059
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Anthrax toxins suppress T lymphocyte activation by disrupting antigen receptor signaling. J Exp Med. 2005 Feb 07; 201(3):325-31.
Score: 0.058
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Discovery of a small molecule that inhibits the interaction of anthrax edema factor with its cellular activator, calmodulin. Chem Biol. 2004 Aug; 11(8):1139-46.
Score: 0.056
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Chemical screening by mass spectrometry to identify inhibitors of anthrax lethal factor. Nat Biotechnol. 2004 Jun; 22(6):717-23.
Score: 0.055
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Structural and kinetic analyses of the interaction of anthrax adenylyl cyclase toxin with reaction products cAMP and pyrophosphate. J Biol Chem. 2004 Jul 09; 279(28):29427-35.
Score: 0.055
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Structure of anthrax edema factor-calmodulin-adenosine 5'-(alpha,beta-methylene)-triphosphate complex reveals an alternative mode of ATP binding to the catalytic site. Biochem Biophys Res Commun. 2004 Apr 30; 317(2):309-14.
Score: 0.055
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Selective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infection. Proc Natl Acad Sci U S A. 2004 Mar 02; 101(9):3242-7.
Score: 0.054
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Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin. Nature. 2002 Jan 24; 415(6870):396-402.
Score: 0.047
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Crystallization and preliminary X-ray study of the edema factor exotoxin adenylyl cyclase domain from Bacillus anthracis in the presence of its activator, calmodulin. Acta Crystallogr D Biol Crystallogr. 2001 Dec; 57(Pt 12):1881-4.
Score: 0.047
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Anthrax edema toxin inhibits endothelial cell chemotaxis via Epac and Rap1. J Biol Chem. 2007 Jul 06; 282(27):19781-7.
Score: 0.017
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Anthrax edema factor potency depends on mode of cell entry. Biochem Biophys Res Commun. 2005 Sep 30; 335(3):850-7.
Score: 0.015
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Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor. EMBO J. 2005 Mar 09; 24(5):929-41.
Score: 0.015
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Calcium dependence of the interaction between calmodulin and anthrax edema factor. J Biol Chem. 2003 Aug 01; 278(31):29261-6.
Score: 0.013