Christopher Weber to Humans
This is a "connection" page, showing publications Christopher Weber has written about Humans.
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0.453
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Histopathologic Evaluation and Single-cell Spatial Transcriptomics of the Colon Reveal Cellular and Molecular Abnormalities Linked to J-Pouch Failure in Patients With Inflammatory Bowel Disease. Cell Mol Gastroenterol Hepatol. 2025; 19(10):101563.
Score: 0.030
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Transcriptional factors in calcium mishandling and atrial fibrillation development. Pflugers Arch. 2021 08; 473(8):1177-1197.
Score: 0.023
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ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction. Circ Res. 2020 07 03; 127(2):e28-e43.
Score: 0.021
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Idiopathic pulmonary fibrosis is associated with tight junction protein alterations. Biochim Biophys Acta Biomembr. 2020 05 01; 1862(5):183205.
Score: 0.021
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Claudin-2-dependent paracellular channels are dynamically gated. Elife. 2015 Nov 14; 4:e09906.
Score: 0.015
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Molecular aspects of tight junction barrier function. Curr Opin Pharmacol. 2014 Dec; 19:84-9.
Score: 0.014
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Chronic pouchitis versus recurrent Crohn's disease: a diagnostic challenge. Dig Dis Sci. 2013 Oct; 58(10):2748-50.
Score: 0.013
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Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux. Mol Biol Cell. 2013 Oct; 24(19):3056-68.
Score: 0.013
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Dynamic properties of the tight junction barrier. Ann N Y Acad Sci. 2012 Jun; 1257:77-84.
Score: 0.012
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Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity. J Biol Chem. 2010 Apr 16; 285(16):12037-46.
Score: 0.010
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Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation. Lab Invest. 2008 Oct; 88(10):1110-20.
Score: 0.009
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Inflammatory bowel disease: is it really just another break in the wall? Gut. 2007 Jan; 56(1):6-8.
Score: 0.008
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Deployment of an Artificial Intelligence Histology Tool to Aid Qualitative Assessment of Histopathology Using the Nancy Histopathology Index in Ulcerative Colitis. Inflamm Bowel Dis. 2025 Jun 13; 31(6):1630-1636.
Score: 0.008
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Multiomic analysis reveals cellular, transcriptomic and epigenetic changes in intestinal pouches of ulcerative colitis patients. Nat Commun. 2025 Jan 21; 16(1):904.
Score: 0.007
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Decentralized clinical trials for medications to reduce the risk of dementia: Consensus report and guidance. Alzheimers Dement. 2024 07; 20(7):4625-4634.
Score: 0.007
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Ozanimod-exposed Patients with Ulcerative Colitis Undergoing Total Colectomy Exhibit Unique Lymph Node Histological Changes. J Crohns Colitis. 2024 Apr 23; 18(4):638-641.
Score: 0.007
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A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network. Circulation. 2024 04 09; 149(15):1205-1230.
Score: 0.007
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Potential Dietary and Therapeutic Strategies Involving Indole-3-Carbinole in Preclinical Models of Intestinal Inflammation. Nutrients. 2023 Nov 30; 15(23).
Score: 0.007
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A novel triptolide analog downregulates NF-?B and induces mitochondrial apoptosis pathways in human pancreatic cancer. Elife. 2023 10 25; 12.
Score: 0.007
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Dynamic regulation of sodium/calcium exchange function in human heart failure. Circulation. 2003 Nov 04; 108(18):2224-9.
Score: 0.007
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Antigen-driven colonic inflammation is associated with development of dysplasia in primary sclerosing cholangitis. Nat Med. 2023 06; 29(6):1520-1529.
Score: 0.007
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Calcium influx via I(NCX) is favored in failing human ventricular myocytes. Ann N Y Acad Sci. 2002 Nov; 976:478-9.
Score: 0.006
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Na/Ca exchange function in intact ventricular myocytes. Ann N Y Acad Sci. 2002 Nov; 976:500-12.
Score: 0.006
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AL101, a gamma-secretase inhibitor, has potent antitumor activity against adenoid cystic carcinoma with activated NOTCH signaling. Cell Death Dis. 2022 08 05; 13(8):678.
Score: 0.006
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Histopathology of Colectomy Specimens Predicts Endoscopic Pouch Phenotype in Patients with Ulcerative Colitis. Dig Dis Sci. 2022 08; 67(8):4020-4031.
Score: 0.006
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T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling. J Clin Invest. 2021 09 01; 131(17).
Score: 0.006
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Objective Visual Analog Scale for Biopsy Diagnosis of Helicobacter pylori Infection in Clinical Practice. Am J Surg Pathol. 2021 05 01; 45(5):672-679.
Score: 0.006
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Wnt-ß-catenin activation epigenetically reprograms Treg cells in inflammatory bowel disease and dysplastic progression. Nat Immunol. 2021 04; 22(4):471-484.
Score: 0.006
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Automated microfluidic platform for dynamic and combinatorial drug screening of tumor organoids. Nat Commun. 2020 10 19; 11(1):5271.
Score: 0.005
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Serum Serotonin Differentiates Between Disease Activity States in Crohn's Patients. Inflamm Bowel Dis. 2020 09 18; 26(10):1607-1618.
Score: 0.005
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Histologic changes caused by injection of a novel submucosal lifting agent for endoscopic resection in GI lesions. Gastrointest Endosc. 2021 02; 93(2):470-476.
Score: 0.005
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Cerebral Cavernous Malformation Proteins in Barrier Maintenance and Regulation. Int J Mol Sci. 2020 Jan 20; 21(2).
Score: 0.005
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Atrial fibrillation risk loci interact to modulate Ca2+-dependent atrial rhythm homeostasis. J Clin Invest. 2019 11 01; 129(11):4937-4950.
Score: 0.005
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Targeted mutational analysis of inflammatory bowel disease-associated colorectal cancers. Hum Pathol. 2019 07; 89:44-50.
Score: 0.005
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The cerebral cavernous malformation disease causing gene KRIT1 participates in intestinal epithelial barrier maintenance and regulation. FASEB J. 2019 02; 33(2):2132-2143.
Score: 0.005
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Human Organoids Share Structural and Genetic Features with Primary Pancreatic Adenocarcinoma Tumors. Mol Cancer Res. 2019 01; 17(1):70-83.
Score: 0.005
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Tryptophan Metabolism through the Kynurenine Pathway is Associated with Endoscopic Inflammation in Ulcerative Colitis. Inflamm Bowel Dis. 2018 06 08; 24(7):1471-1480.
Score: 0.005
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Safety and Efficacy of Combination Treatment With Calcineurin Inhibitors and Vedolizumab in Patients With Refractory Inflammatory Bowel Disease. Clin Gastroenterol Hepatol. 2019 02; 17(3):486-493.
Score: 0.005
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Vedolizumab as Induction and Maintenance for Inflammatory Bowel Disease: 12-month Effectiveness and Safety. Inflamm Bowel Dis. 2018 03 19; 24(4):849-860.
Score: 0.005
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Unusual gastric subepithelial tumor: primary mixed acinar-endocrine neoplasm in an anemic woman. Gastrointest Endosc. 2018 May; 87(5):1355-1356.
Score: 0.004
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Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis Frequently Have Subclinical Inflammation in the Proximal Colon. Clin Gastroenterol Hepatol. 2018 Jan; 16(1):68-74.
Score: 0.004
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Early Transcriptomic Changes in the Ileal Pouch Provide Insight into the Molecular Pathogenesis of Pouchitis and Ulcerative Colitis. Inflamm Bowel Dis. 2017 03; 23(3):366-378.
Score: 0.004
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Interleukin-15 promotes intestinal dysbiosis with butyrate deficiency associated with increased susceptibility to colitis. ISME J. 2017 01; 11(1):15-30.
Score: 0.004
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Pitx2 modulates a Tbx5-dependent gene regulatory network to maintain atrial rhythm. Sci Transl Med. 2016 08 31; 8(354):354ra115.
Score: 0.004
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Higher Order Chromatin Modulator Cohesin SA1 Is an Early Biomarker for Colon Carcinogenesis: Race-Specific Implications. Cancer Prev Res (Phila). 2016 Nov; 9(11):844-854.
Score: 0.004
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New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections. Sci Rep. 2016 07 14; 6:29179.
Score: 0.004
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Insights into the pathogenesis of ulcerative colitis from a murine model of stasis-induced dysbiosis, colonic metaplasia, and genetic susceptibility. Am J Physiol Gastrointest Liver Physiol. 2016 06 01; 310(11):G973-88.
Score: 0.004
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Spectral biomarkers for chemoprevention of colonic neoplasia: a placebo-controlled double-blinded trial with aspirin. Gut. 2017 02; 66(2):285-292.
Score: 0.004
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S&R Foundation 15th Anniversary. Physiologist. 2015 Sep; 58(5):241-2.
Score: 0.004
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The Thr300Ala variant in ATG16L1 is associated with improved survival in human colorectal cancer and enhanced production of type I interferon. Gut. 2016 Mar; 65(3):456-64.
Score: 0.004
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Rectal leiomyosarcoma in association with ulcerative colitis: a rare condition with an unusual presentation. Int J Colorectal Dis. 2014 Jul; 29(7):887-8.
Score: 0.003
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ß-Catenin promotes colitis and colon cancer through imprinting of proinflammatory properties in T cells. Sci Transl Med. 2014 Feb 26; 6(225):225ra28.
Score: 0.003
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FOXO3 growth inhibition of colonic cells is dependent on intraepithelial lipid droplet density. J Biol Chem. 2013 Jun 07; 288(23):16274-16281.
Score: 0.003
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Bifidobacteria stabilize claudins at tight junctions and prevent intestinal barrier dysfunction in mouse necrotizing enterocolitis. Am J Pathol. 2013 May; 182(5):1595-606.
Score: 0.003
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Capsaicin induces NKCC1 internalization and inhibits chloride secretion in colonic epithelial cells independently of TRPV1. Am J Physiol Gastrointest Liver Physiol. 2013 Jan 15; 304(2):G142-56.
Score: 0.003
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Topical polyethylene glycol as a novel chemopreventive agent for oral cancer via targeting of epidermal growth factor response. PLoS One. 2012; 7(6):e38047.
Score: 0.003
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Targeted deletion of MyD88 in intestinal epithelial cells results in compromised antibacterial immunity associated with downregulation of polymeric immunoglobulin receptor, mucin-2, and antibacterial peptides. Mucosal Immunol. 2012 Sep; 5(5):501-12.
Score: 0.003
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Polyethylene glycol diminishes pathological effects of Citrobacter rodentium infection by blocking bacterial attachment to the colonic epithelia. Gut Microbes. 2011 Sep 01; 2(5):267-73.
Score: 0.003
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Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity. BMC Cancer. 2011 Jun 03; 11:219.
Score: 0.003
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Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function. J Cell Biol. 2011 May 02; 193(3):565-82.
Score: 0.003
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Tight junction pore and leak pathways: a dynamic duo. Annu Rev Physiol. 2011; 73:283-309.
Score: 0.003
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Tumor suppressor FOXO3 mediates signals from the EGF receptor to regulate proliferation of colonic cells. Am J Physiol Gastrointest Liver Physiol. 2011 Feb; 300(2):G264-72.
Score: 0.003
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Phosphoinositide 3-kinase signaling mediates beta-catenin activation in intestinal epithelial stem and progenitor cells in colitis. Gastroenterology. 2010 Sep; 139(3):869-81, 881.e1-9.
Score: 0.003
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MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function. Proc Natl Acad Sci U S A. 2010 May 04; 107(18):8237-41.
Score: 0.003
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Tumor suppressor FOXO3 participates in the regulation of intestinal inflammation. Lab Invest. 2009 Sep; 89(9):1053-62.
Score: 0.003
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Retinoic acid-induced gene-1 (RIG-I) associates with the actin cytoskeleton via caspase activation and recruitment domain-dependent interactions. J Biol Chem. 2009 Mar 06; 284(10):6486-94.
Score: 0.002
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Tumor suppressor Foxo3a is involved in the regulation of lipopolysaccharide-induced interleukin-8 in intestinal HT-29 cells. Infect Immun. 2008 Oct; 76(10):4677-85.
Score: 0.002
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The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state. J Cell Biol. 2008 May 19; 181(4):683-95.
Score: 0.002
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MMP25 (MT6-MMP) is highly expressed in human colon cancer, promotes tumor growth, and exhibits unique biochemical properties. J Biol Chem. 2007 Jul 27; 282(30):21998-2010.
Score: 0.002
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Modulation of the pancreatic islet beta-cell-delayed rectifier potassium channel Kv2.1 by the polyunsaturated fatty acid arachidonate. J Biol Chem. 2007 Mar 09; 282(10):7442-9.
Score: 0.002
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Cellular basis of abnormal calcium transients of failing human ventricular myocytes. Circ Res. 2003 Apr 04; 92(6):651-8.
Score: 0.002
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Modulation of contractility in failing human myocytes by reverse-mode Na/Ca exchange. Ann N Y Acad Sci. 2002 Nov; 976:466-71.
Score: 0.002