LuciaRothman-DenesLucia Rothman-Denes41.78927490000000-87.60125000000000996Rothman-Denes, LuciaProfessorprns:awardConferredByaward conferred byprns:coAuthorOfcoauthor ofprns:emailEncryptedemail addressprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:trainingAtOrganizationeducational organizationprns:trainingLocationtraining locationprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipvivo:awardOrHonorawards and honorsAward or Honor Receiptvivo:degreeEarneddegree earnedDepartmentvivo:educationalTrainingeducation and trainingEducational TrainingGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:majorFieldmajor field of degreevivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD003090Living Beings8590.987626ColiphagesBryanDickinson02tqa6gbCuPXsW9naE/t8mL1sc65/A==Bryan Dickinson41.7886000000000087.598699999999993482Dickinson, BryanProfessor Biochemistry and Molecular BiologyMolecular Genetics and Cell BiologyD004926Living Beings1715960.783578Escherichia coliAuthorship 107653Authorship 107645Authorship 11214Authorship 1212Authorship 128015Authorship 1332Authorship 132134Authorship 133764Authorship 159962Authorship 151352Authorship 161411Authorship 17094Authorship 1521031964School of Sciences, University of Buenos AiresBuenos Aires, ArgentinaSchool of Sciences, University of Buenos Aires, ChemistryLicenciadoChemistry1967School of Sciences, University of Buenos AiresBuenos Aires, ArgentinaSchool of Sciences, University of Buenos Aires, BiochemistryPhDBiochemistry1970NIAMD, NIHBethesda, MD, USANIAMD, NIH, Molecular BiologynoneMolecular Biology1974University of ChicagoChicago, IL, USAUniversity of Chicago, VirologynoneVirologyUniversity of Chicago1988Award for excellence in graduate teachingAmerican Academy of Microbiology1992elected fellowAmerican Association for the Advancement of Science2000elected fellowAmerican Academy of Arts and Sciences2001elected memberNational Academy of Sciences, USA2014elected memberAuthorship 241253Authorship 185857Authorship 229712Authorship 232454Authorship 310772Authorship 3343Authorship 3596Authorship 39802Authorship 34652Authorship 366272Authorship 319163Authorship 368373Authorship 39675Authorship 329111Authorship 439414Authorship 46255Authorship 346113Authorship 346595Authorship 34142Authorship 3792Authorship 345851Authorship 3782Authorship 49743Authorship 52294Authorship 55383Authorship 366414Authorship 39662D014771Living Beings23590.964463VirionAuthorship 61772Authorship 64571Authorship 65902Authorship 69291Authorship 74984Authorship 82073Authorship 92454Authorship 98063Authorship 47748Authorship 435572Authorship 52403D012321Chemicals & Drugs331020.920557DNA-Directed RNA PolymerasesAuthorship 67441Authorship 72753Authorship 64761Authorship 67721Authorship 63822Authorship 66051Authorship 73503Authorship 117014Authorship 211348Authorship 214778Authorship 2662842Authorship 3333Authorship 53725Authorship 55374Authorship 749921383090Markiewicz P, Malone C, Chase JW, Rothman-Denes LBGenes & developmentEscherichia coli single-stranded DNA-binding protein is a supercoiled template-dependent transcriptional activator of N4 virion RNA polymerase. Genes Dev. 1992 Oct; 6(10):2010-9.Genes Dev1992-10-01T00:00:001992Escherichia coli single-stranded DNA-binding protein is a supercoiled template-dependent transcriptional activator of N4 virion RNA polymerase.8548819Glucksmann-Kuis MA, Dai X, Markiewicz P, Rothman-Denes LBCellE. coli SSB activates N4 virion RNA polymerase promoters by stabilizing a DNA hairpin required for promoter recognition. Cell. 1996 Jan 12; 84(1):147-54.Cell1996-01-12T00:00:001996E. coli SSB activates N4 virion RNA polymerase promoters by stabilizing a DNA hairpin required for promoter recognition.166384Epstein W, Rothman-Denes LB, Hesse JProceedings of the National Academy of Sciences of the United States of AmericaAdenosine 3':5'-cyclic monophosphate as mediator of catabolite repression in Escherichia coli. Proc Natl Acad Sci U S A. 1975 Jun; 72(6):2300-4.Proc Natl Acad Sci U S A1975-06-01T00:00:001975Adenosine 3':5'-cyclic monophosphate as mediator of catabolite repression in Escherichia coli.8902792Miller A, Dai X, Choi M, Glucksmann-Kuis MA, Rothman-Denes LBMethods in enzymologySingle-stranded DNA-binding proteins as transcriptional activators. Methods Enzymol. 1996; 274:9-20.Methods Enzymol1996-01-01T00:00:001996Single-stranded DNA-binding proteins as transcriptional activators.171971Hesse JE, Rothman-Denes LB, Epstein WAnalytical biochemistryA convenient erythrocyte membrane cyclic AMP binding assay. Anal Biochem. 1975 Sep; 68(1):202-8.Anal Biochem1975-09-01T00:00:001975A convenient erythrocyte membrane cyclic AMP binding assay.9122167Dai X, Greizerstein MB, Nadas-Chinni K, Rothman-Denes LBProceedings of the National Academy of Sciences of the United States of AmericaSupercoil-induced extrusion of a regulatory DNA hairpin. Proc Natl Acad Sci U S A. 1997 Mar 18; 94(6):2174-9.Proc Natl Acad Sci U S A1997-03-18T00:00:001997Supercoil-induced extrusion of a regulatory DNA hairpin.9761672Dai X, Kloster M, Rothman-Denes LBJournal of molecular biologySequence-dependent extrusion of a small DNA hairpin at the N4 virion RNA polymerase promoters. J Mol Biol. 1998; 283(1):43-58.J Mol Biol1998-01-01T00:00:001998Sequence-dependent extrusion of a small DNA hairpin at the N4 virion RNA polymerase promoters.1643660Glucksmann MA, Markiewicz P, Malone C, Rothman-Denes LBCellSpecific sequences and a hairpin structure in the template strand are required for N4 virion RNA polymerase promoter recognition. Cell. 1992 Aug 07; 70(3):491-500.Cell1992-08-07T00:00:001992Specific sequences and a hairpin structure in the template strand are required for N4 virion RNA polymerase promoter recognition.9732275Dai X, Rothman-Denes LBGenes & developmentSequence and DNA structural determinants of N4 virion RNA polymerase-promoter recognition. Genes Dev. 1998 Sep 01; 12(17):2782-90.Genes Dev1998-09-01T00:00:001998Sequence and DNA structural determinants of N4 virion RNA polymerase-promoter recognition.10384271Rothman-Denes LB, Dai X, Davydova E, Carter R, Kazmierczak KCold Spring Harbor symposia on quantitative biologyTranscriptional regulation by DNA structural transitions and single-stranded DNA-binding proteins. Cold Spring Harb Symp Quant Biol. 1998; 63:63-73.Cold Spring Harb Symp Quant Biol1998-01-01T00:00:001998Transcriptional regulation by DNA structural transitions and single-stranded DNA-binding proteins.11226277Van Dyk TK, Wei Y, Hanafey MK, Dolan M, Reeve MJ, Rafalski JA, Rothman-Denes LB, LaRossa RAProceedings of the National Academy of Sciences of the United States of AmericaA genomic approach to gene fusion technology. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2555-60.Proc Natl Acad Sci U S A2001-02-13T00:00:002001A genomic approach to gene fusion technology.12193610Willis SH, Kazmierczak KM, Carter RH, Rothman-Denes LBJournal of bacteriologyN4 RNA polymerase II, a heterodimeric RNA polymerase with homology to the single-subunit family of RNA polymerases. J Bacteriol. 2002 Sep; 184(18):4952-61.J Bacteriol2002-09-01T00:00:002002N4 RNA polymerase II, a heterodimeric RNA polymerase with homology to the single-subunit family of RNA polymerases.12411499Kazmierczak KM, Davydova EK, Mustaev AA, Rothman-Denes LBThe EMBO journalThe phage N4 virion RNA polymerase catalytic domain is related to single-subunit RNA polymerases. EMBO J. 2002 Nov 01; 21(21):5815-23.EMBO J2002-11-01T00:00:002002The phage N4 virion RNA polymerase catalytic domain is related to single-subunit RNA polymerases.12876194Davydova EK, Rothman-Denes LBProceedings of the National Academy of Sciences of the United States of AmericaEscherichia coli single-stranded DNA-binding protein mediates template recycling during transcription by bacteriophage N4 virion RNA polymerase. Proc Natl Acad Sci U S A. 2003 Aug 05; 100(16):9250-5.Proc Natl Acad Sci U S A2003-07-22T00:00:002003Escherichia coli single-stranded DNA-binding protein mediates template recycling during transcription by bacteriophage N4 virion RNA polymerase.D025522Living Beings3240.972695Bacteriophage N417790464Rothman-Denes LScience (New York, N.Y.)Transposons. Science. 1982 Jan 01; 215(4528):52-3.Science1982-01-01T00:00:001982Transposons.18358764Rothman-Denes LB, Parsot CCurrent opinion in microbiologyCell regulation. Curr Opin Microbiol. 2008 Apr; 11(2):75-7.Curr Opin Microbiol2008-03-21T00:00:002008Cell regulation.17174325Stojkovic EA, Rothman-Denes LBJournal of molecular biologyColiphage N4 N-acetylmuramidase defines a new family of murein hydrolases. J Mol Biol. 2007 Feb 16; 366(2):406-19.J Mol Biol2006-11-11T00:00:002006Coliphage N4 N-acetylmuramidase defines a new family of murein hydrolases.14712636Davydova EK, Kazmierczak KM, Rothman-Denes LBMethods in enzymologyBacteriophage N4-coded, virion-encapsulated DNA-dependent RNA polymerase. Methods Enzymol. 2003; 370:83-94.Methods Enzymol2003-01-01T00:00:002003Bacteriophage N4-coded, virion-encapsulated DNA-dependent RNA polymerase.19011026McPartland J, Rothman-Denes LBJournal of bacteriologyThe tail sheath of bacteriophage N4 interacts with the Escherichia coli receptor. J Bacteriol. 2009 Jan; 191(2):525-32.J Bacteriol2008-11-14T00:00:002008The tail sheath of bacteriophage N4 interacts with the Escherichia coli receptor.19015264Davydova EK, Kaganman I, Kazmierczak KM, Rothman-Denes LBThe Journal of biological chemistryIdentification of bacteriophage N4 virion RNA polymerase-nucleic acid interactions in transcription complexes. J Biol Chem. 2009 Jan 23; 284(4):1962-70.J Biol Chem2008-11-17T00:00:002008Identification of bacteriophage N4 virion RNA polymerase-nucleic acid interactions in transcription complexes.2407852Abravaya K, Rothman-Denes LBJournal of molecular biologyN4 RNA polymerase II sites of transcription initiation. J Mol Biol. 1990 Jan 20; 211(2):359-72.J Mol Biol1990-01-20T00:00:001990N4 RNA polymerase II sites of transcription initiation.18362338Murakami KS, Davydova EK, Rothman-Denes LBProceedings of the National Academy of Sciences of the United States of AmericaX-ray crystal structure of the polymerase domain of the bacteriophage N4 virion RNA polymerase. Proc Natl Acad Sci U S A. 2008 Apr 01; 105(13):5046-51.Proc Natl Acad Sci U S A2008-03-24T00:00:002008X-ray crystal structure of the polymerase domain of the bacteriophage N4 virion RNA polymerase.322130Falco SC, Laan KV, Rothman-Denes LBProceedings of the National Academy of Sciences of the United States of AmericaVirion-associated RNA polymerase required for bacteriophage N4 development. Proc Natl Acad Sci U S A. 1977 Feb; 74(2):520-3.Proc Natl Acad Sci U S A1977-02-01T00:00:001977Virion-associated RNA polymerase required for bacteriophage N4 development.320753vander Laan K, Falco SC, Rothman-Denes LBVirologyThe program of RNA synthesis in N4-infected Escherichia coli. Virology. 1977 Feb; 76(2):596-601.Virology1977-02-01T00:00:001977The program of RNA synthesis in N4-infected Escherichia coli.356050Falco SC, Zivin R, Rothman-Denes LBProceedings of the National Academy of Sciences of the United States of AmericaNovel template requirements of N4 virion RNA polymerase. Proc Natl Acad Sci U S A. 1978 Jul; 75(7):3220-4.Proc Natl Acad Sci U S A1978-07-01T00:00:001978Novel template requirements of N4 virion RNA polymerase.2670887Kiino DR, Rothman-Denes LBJournal of bacteriologyGenetic analysis of bacteriophage N4 adsorption. J Bacteriol. 1989 Sep; 171(9):4595-602.J Bacteriol1989-09-01T00:00:001989Genetic analysis of bacteriophage N4 adsorption.19061645Gleghorn ML, Davydova EK, Rothman-Denes LB, Murakami KSMolecular cellStructural basis for DNA-hairpin promoter recognition by the bacteriophage N4 virion RNA polymerase. Mol Cell. 2008 Dec 05; 32(5):707-17.Mol Cell2008-12-05T00:00:002008Structural basis for DNA-hairpin promoter recognition by the bacteriophage N4 virion RNA polymerase.18374942Choi KH, McPartland J, Kaganman I, Bowman VD, Rothman-Denes LB, Rossmann MGJournal of molecular biologyInsight into DNA and protein transport in double-stranded DNA viruses: the structure of bacteriophage N4. J Mol Biol. 2008 May 02; 378(3):726-36.J Mol Biol2008-03-04T00:00:002008Insight into DNA and protein transport in double-stranded DNA viruses: the structure of bacteriophage N4.15746409Altman S, Bassler BL, Beckwith J, Belfort M, Berg HC, Bloom B, Brenchley JE, Campbell A, Collier RJ, Connell N, Cozzarelli NR, Craig NL, Darst S, Ebright RH, Elledge SJ, Falkow S, Galan JE, Gottesman M, Gourse R, Grindley ND, Gross CA, Grossman A, Hochschild A, Howe M, Hurwitz J, Isberg RR, Kaplan S, Kornberg A, Kustu SG, Landick RC, Landy A, Levy SB, Losick R, Long SR, Maloy SR, Mekalanos JJ, Neidhardt FC, Pace NR, Ptashne M, Roberts JW, Roth JR, Rothman-Denes LB, Salyers A, Schaechter M, Shapiro L, Silhavy TJ, Simon MI, Walker G, Yanofsky C, Zinder NScience (New York, N.Y.)An open letter to Elias Zerhouni. Science. 2005 Mar 04; 307(5714):1409-10.Science2005-03-04T00:00:002005An open letter to Elias Zerhouni.4343116Rothman-Denes LB, Haselkorn R, Schito GCVirologySelective shutoff of catabolite-sensitive host syntheses by bacroxyurea pharmaco mutation genes coliphages growth l virus replication escherichia coli growth l lysogeny crosses genetic coliteriophage N4. Virology. 1972 Oct; 50(1):95-102.Virology1972-10-01T00:00:001972Selective shutoff of catabolite-sensitive host syntheses by bacroxyurea pharmaco mutation genes coliphages growth l virus replication escherichia coli growth l lysogeny crosses genetic coliteriophage N4.4581230Haselkorn R, Rothman-Denes LBAnnual review of biochemistryProtein synthesis. Annu Rev Biochem. 1973; 42:397-438.Annu Rev Biochem1973-01-01T00:00:001973Protein synthesis.4601458Rothman-Denes LB, Schito GCVirologyNovel transcribing activities in N4-infected Escherichia coli. Virology. 1974 Jul; 60(1):65-72.Virology1974-07-01T00:00:001974Novel transcribing activities in N4-infected Escherichia coli.8226648Kiino DR, Licudine R, Wilt K, Yang DH, Rothman-Denes LBJournal of bacteriologyA cytoplasmic protein, NfrC, is required for bacteriophage N4 adsorption. J Bacteriol. 1993 Nov; 175(21):7074-80.J Bacteriol1993-11-01T00:00:001993A cytoplasmic protein, NfrC, is required for bacteriophage N4 adsorption.4928009Rothman-Denes L, Martin RGJournal of bacteriologyTwo mutations in the first gene of the histidine operon of Salmonella typhimurium affecting control. J Bacteriol. 1971 Apr; 106(1):227-37.J Bacteriol1971-04-01T00:00:001971Two mutations in the first gene of the histidine operon of Salmonella typhimurium affecting control.380137Falco SC, Rothman-Denes LBVirologyBacteriophage N4-induced transcribing activities in Escherichia coli. I. Detection and characterization in cell extracts. Virology. 1979 Jun; 95(2):454-65.Virology1979-06-01T00:00:001979Bacteriophage N4-induced transcribing activities in Escherichia coli. I. Detection and characterization in cell extracts.3525547Rist JK, Pearle M, Sugino A, Rothman-Denes LBThe Journal of biological chemistryDevelopment of an in vitro bacteriophage N4 DNA replication system. J Biol Chem. 1986 Aug 15; 261(23):10506-10.J Biol Chem1986-08-15T00:00:001986Development of an in vitro bacteriophage N4 DNA replication system.3006344Guinta D, Stambouly J, Falco SC, Rist JK, Rothman-Denes LBVirologyHost and phage-coded functions required for coliphage N4 DNA replication. Virology. 1986 Apr 15; 150(1):33-44.Virology1986-04-15T00:00:001986Host and phage-coded functions required for coliphage N4 DNA replication.21205014Yano ST, Rothman-Denes LBMolecular microbiologyA phage-encoded inhibitor of Escherichia coli DNA replication targets the DNA polymerase clamp loader. Mol Microbiol. 2011 Mar; 79(5):1325-38.Mol Microbiol2011-01-18T00:00:002011A phage-encoded inhibitor of Escherichia coli DNA replication targets the DNA polymerase clamp loader.21321236Gleghorn ML, Davydova EK, Basu R, Rothman-Denes LB, Murakami KSProceedings of the National Academy of Sciences of the United States of AmericaX-ray crystal structures elucidate the nucleotidyl transfer reaction of transcript initiation using two nucleotides. Proc Natl Acad Sci U S A. 2011 Mar 01; 108(9):3566-71.Proc Natl Acad Sci U S A2011-02-14T00:00:002011X-ray crystal structures elucidate the nucleotidyl transfer reaction of transcript initiation using two nucleotides.380138Falco SC, Rothman-Denes LBVirologyBacteriophage N4-induced transcribing activities in Escherichia coli. II. Association of the N4 transcriptional apparatus with the cytoplasmic membrane. Virology. 1979 Jun; 95(2):466-75.Virology1979-06-01T00:00:001979Bacteriophage N4-induced transcribing activities in Escherichia coli. II. Association of the N4 transcriptional apparatus with the cytoplasmic membrane.5553327Rothman-Denes LB, Cabib EBiochemistryGlucose 6-phosphate dependent and independent forms of yeast glycogen synthetase. Their properties and interconversions. Biochemistry. 1971 Mar 30; 10(7):1236-42.Biochemistry1971-03-30T00:00:001971Glucose 6-phosphate dependent and independent forms of yeast glycogen synthetase. Their properties and interconversions.3341115Malone C, Spellman S, Hyman D, Rothman-Denes LBVirologyCloning and generation of a genetic map of bacteriophage N4 DNA. Virology. 1988 Feb; 162(2):328-36.Virology1988-02-01T00:00:001988Cloning and generation of a genetic map of bacteriophage N4 DNA.3525553Guinta D, Lindberg G, Rothman-Denes LBThe Journal of biological chemistryBacteriophage N4-coded 5'----3' exonuclease. Purification and characterization. J Biol Chem. 1986 Aug 15; 261(23):10736-43.J Biol Chem1986-08-15T00:00:001986Bacteriophage N4-coded 5'----3' exonuclease. Purification and characterization.3986911Haynes LL, Rothman-Denes LBCellN4 virion RNA polymerase sites of transcription initiation. Cell. 1985 Jun; 41(2):597-605.Cell1985-06-01T00:00:001985N4 virion RNA polymerase sites of transcription initiation.6249023Zivin R, Malone C, Rothman-Denes LBVirologyPhysical map of coliphage N4 DNA. Virology. 1980 Jul 15; 104(1):205-18.Virology1980-07-15T00:00:001980Physical map of coliphage N4 DNA.4270090Cabib E, Rothman-Denes LB, Huang KAnnals of the New York Academy of SciencesThe regulation of glycogen synthesis in yeast. Ann N Y Acad Sci. 1973 Feb 09; 210:192-206.Ann N Y Acad Sci1973-02-09T00:00:001973The regulation of glycogen synthesis in yeast.4351384Rothman-Denes LB, Hesse JE, Epstein WJournal of bacteriologyRole of cyclic adenosine 3',5'-monophosphate in the in vivo expression of the galactose operon of Escherichia coli. J Bacteriol. 1973 Jun; 114(3):1040-4.J Bacteriol1973-06-01T00:00:001973Role of cyclic adenosine 3',5'-monophosphate in the in vivo expression of the galactose operon of Escherichia coli.6344415Zehring WA, Falco SC, Malone C, Rothman-Denes LBVirologyBacteriophage N4-induced transcribing activities in E. coli. III. A third cistron required for N4 RNA polymerase II activity. Virology. 1983 Apr 30; 126(2):678-87.Virology1983-04-30T00:00:001983Bacteriophage N4-induced transcribing activities in E. coli. III. A third cistron required for N4 RNA polymerase II activity.6345539Zehring WA, Rothman-Denes LBThe Journal of biological chemistryPurification and characterization of coliphage N4 RNA polymerase II activity from infected cell extracts. J Biol Chem. 1983 Jul 10; 258(13):8074-80.J Biol Chem1983-07-10T00:00:001983Purification and characterization of coliphage N4 RNA polymerase II activity from infected cell extracts.6276570Zivin R, Zehring W, Rothman-Denes LBJournal of molecular biologyTranscriptional map of bacteriophage N4. Location and polarity of N4 RNAs. J Mol Biol. 1981 Oct 25; 152(2):335-56.J Mol Biol1981-10-25T00:00:001981Transcriptional map of bacteriophage N4. Location and polarity of N4 RNAs.3172206Ohmori H, Haynes LL, Rothman-Denes LBJournal of molecular biologyStructure of the ends of the coliphage N4 genome. J Mol Biol. 1988 Jul 05; 202(1):1-10.J Mol Biol1988-07-05T00:00:001988Structure of the ends of the coliphage N4 genome.3344199Markiewicz P, Glucksmann A, Rothman-Denes LBNucleic acids researchN4 virion DNA dependent-RNA polymerase: initiation sequences utilized by the enzyme on heterologous templates. Nucleic Acids Res. 1988 Feb 11; 16(3):1011-26.Nucleic Acids Res1988-02-11T00:00:001988N4 virion DNA dependent-RNA polymerase: initiation sequences utilized by the enzyme on heterologous templates.17438270Davydova EK, Santangelo TJ, Rothman-Denes LBProceedings of the National Academy of Sciences of the United States of AmericaBacteriophage N4 virion RNA polymerase interaction with its promoter DNA hairpin. Proc Natl Acad Sci U S A. 2007 Apr 24; 104(17):7033-8.Proc Natl Acad Sci U S A2007-04-16T00:00:002007Bacteriophage N4 virion RNA polymerase interaction with its promoter DNA hairpin.7673246Choi M, Miller A, Cho NY, Rothman-Denes LBThe Journal of biological chemistryIdentification, cloning, and characterization of the bacteriophage N4 gene encoding the single-stranded DNA-binding protein. A protein required for phage replication, recombination, and late transcription. J Biol Chem. 1995 Sep 22; 270(38):22541-7.J Biol Chem1995-09-22T00:00:001995Identification, cloning, and characterization of the bacteriophage N4 gene encoding the single-stranded DNA-binding protein. A protein required for phage replication, recombination, and late transcription.4987630Rothman-Denes LB, Cabib EProceedings of the National Academy of Sciences of the United States of AmericaTwo forms of yeast glycogen synthetase and their role in glycogen accumulation. Proc Natl Acad Sci U S A. 1970 Jul; 66(3):967-74.Proc Natl Acad Sci U S A1970-07-01T00:00:001970Two forms of yeast glycogen synthetase and their role in glycogen accumulation.2429314Muglia L, Rothman-Denes LBProceedings of the National Academy of Sciences of the United States of AmericaCell type-specific negative regulatory element in the control region of the rat alpha-fetoprotein gene. Proc Natl Acad Sci U S A. 1986 Oct; 83(20):7653-7.Proc Natl Acad Sci U S A1986-10-01T00:00:001986Cell type-specific negative regulatory element in the control region of the rat alpha-fetoprotein gene.2663865Abravaya K, Rothman-Denes LBThe Journal of biological chemistryIn vitro requirements for N4 RNA polymerase II-specific initiation. J Biol Chem. 1989 Jul 25; 264(21):12695-9.J Biol Chem1989-07-25T00:00:001989In vitro requirements for N4 RNA polymerase II-specific initiation.2663866Lindberg G, Kowalczykowski SC, Rist JK, Sugino A, Rothman-Denes LBThe Journal of biological chemistryPurification and characterization of the coliphage N4-coded single-stranded DNA binding protein. J Biol Chem. 1989 Jul 25; 264(21):12700-8.J Biol Chem1989-07-25T00:00:001989Purification and characterization of the coliphage N4-coded single-stranded DNA binding protein.3403528Lindberg GK, Rist JK, Kunkel TA, Sugino A, Rothman-Denes LBThe Journal of biological chemistryPurification and characterization of bacteriophage N4-induced DNA polymerase. J Biol Chem. 1988 Aug 15; 263(23):11319-26.J Biol Chem1988-08-15T00:00:001988Purification and characterization of bacteriophage N4-induced DNA polymerase.9054361Miller A, Wood D, Ebright RH, Rothman-Denes LBScience (New York, N.Y.)RNA polymerase beta' subunit: a target of DNA binding-independent activation. Science. 1997 Mar 14; 275(5306):1655-7.Science1997-03-14T00:00:001997RNA polymerase beta' subunit: a target of DNA binding-independent activation.10322174Dai X, Rothman-Denes LBCurrent opinion in microbiologyDNA structure and transcription. Curr Opin Microbiol. 1999 Apr; 2(2):126-30.Curr Opin Microbiol1999-04-01T00:00:001999DNA structure and transcription.12975320Carter RH, Demidenko AA, Hattingh-Willis S, Rothman-Denes LBGenes & developmentPhage N4 RNA polymerase II recruitment to DNA by a single-stranded DNA-binding protein. Genes Dev. 2003 Sep 15; 17(18):2334-45.Genes Dev2003-09-15T00:00:002003Phage N4 RNA polymerase II recruitment to DNA by a single-stranded DNA-binding protein.3067733Hartmann GR, Biebricher C, Glaser SJ, Grosse F, Katzameyer MJ, Lindner AJ, Mosig H, Nasheuer HP, Rothman-Denes LB, Schäffner ARBiological chemistry Hoppe-SeylerTwelfth Fritz Lipmann lecture. Initiation of transcription--a general tool for affinity labeling of RNA polymerases by autocatalysis. Biol Chem Hoppe Seyler. 1988 Sep; 369(9):775-88.Biol Chem Hoppe Seyler1988-09-01T00:00:001988Twelfth Fritz Lipmann lecture. Initiation of transcription--a general tool for affinity labeling of RNA polymerases by autocatalysis.6989837Falco SC, Zehring W, Rothman-Denes LBThe Journal of biological chemistryDNA-dependent RNA polymerase from bacteriophage N4 virions. Purification and characterization. J Biol Chem. 1980 May 10; 255(9):4339-47.J Biol Chem1980-05-10T00:00:001980DNA-dependent RNA polymerase from bacteriophage N4 virions. Purification and characterization.7877167Cho NY, Choi M, Rothman-Denes LBJournal of molecular biologyThe bacteriophage N4-coded single-stranded DNA-binding protein (N4SSB) is the transcriptional activator of Escherichia coli RNA polymerase at N4 late promoters. J Mol Biol. 1995 Mar 03; 246(4):461-71.J Mol Biol1995-03-03T00:00:001995The bacteriophage N4-coded single-stranded DNA-binding protein (N4SSB) is the transcriptional activator of Escherichia coli RNA polymerase at N4 late promoters.8226649Kiino DR, Singer MS, Rothman-Denes LBJournal of bacteriologyTwo overlapping genes encoding membrane proteins required for bacteriophage N4 adsorption. J Bacteriol. 1993 Nov; 175(21):7081-5.J Bacteriol1993-11-01T00:00:001993Two overlapping genes encoding membrane proteins required for bacteriophage N4 adsorption.ChuanHe1Gp8Cq8dHMzMknJtY0fp/Cv/+94=Chuan He0.000000000000000.000000000000003123He, ChuanProfessorhttps://voices.uchicago.edu/jocelynmalamylab/Malamy Lab websitehttps://openwetware.org/wiki/Pan_LabPan Lab sitehttp://shb-lab.orgHorne-Badovinac Lab Websitehttp://he-group.uchicago.eduMy Lab Sitehttp://sosnick.uchicago.edu/Sosnick lab websitehttp://glotzerlab.uchicago.eduGlotzer Labhttps://staley.uchicago.eduStaley Lab Websitehttps://voices.uchicago.edu/kovarlab/Kovar Lab Website2016-06-30NIHROTHMAN-DENES, LUCIA B. B1978-05-01Transcribing Activities in N4 Infected E. ColiR01AI0125752026-06-30NIHNOVEMBRE, JOHN ;ROTHMAN-DENES, LUCIA B. B;RUTHENBURG, ALEXANDER JACKSON;THORNTON, JOSEPH W2021-07-01Genetic Mechanisms and EvolutionT32GM1397822001-04-30NIHROTHMAN-DENES, LUCIA B. B1996-05-01ACTIVATION OF RNA POLYMERASE BY SSDNA BINDING PROTEINR01GM0544311992-03-31NIHROTHMAN-DENES, LUCIA B. B1987-04-01REGULATION OF EUKAROYTIC GENE EXPRESSIONR01GM0384161996-06-30NIHROTHMAN-DENES, LUCIA B. B1985-07-01MECHANISM OF REPLICATION OF LINEAR DNAR01GM0351701995-09-30NIHROTHMAN-DENES, LUCIA B. B1990-07-01BIOTECHNOLOGYT32GM0083691992-05-31NIHROTHMAN-DENES, LUCIA B. B1991-06-01CONFERENCE ON BIOLOGICAL REGULATORY MECHANISMSR13GM0466402021-06-30NIHROTHMAN-DENES, LUCIA B. B1975-07-01Genetics and RegulationT32GM007197Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorCo-Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorShoYanoSho Yano41.7886000000000087.598699999999994372Yano, ShoAssistant ProfessorChemistryBSD MicrobiologyMol Gen/Cell BioUniversity of ChicagoBernardRoizman1Wd7BaAHHaLLnnN+bUfg02fp+4Wo6r1Xc3h9eaOOFmI=Bernard Roizman41.78927490000000-87.601250000000001112Roizman, BernardEmeritus/Emerita, ProfessorJonathan P.Staley3XF9Cq0QeczMknJtY0fp/Cv/+94=Jonathan P. Staley41.78927490000000-87.601250000000001221Staley, Jonathan P.ProfessorTaoPanw2NmG6AbOfnamXNnYUHhvWD+6g==Tao Pan41.78927490000000-87.601250000000001308Pan, TaoProfessorRobertHaselkornRobert Haselkorn41.78927490000000-87.601250000000001490Haselkorn, RobertProfessor EmeritusSallyHorne-BadovinacSally Horne-Badovinac41.78927490000000-87.601250000000002252Horne-Badovinac, SallyProfessorMichael A.GlotzerMichael A. Glotzer41.78927490000000-87.601250000000002437Glotzer, Michael A.ProfessorDavid R.Kovar02lmHaAHOe7KlTRxY07n8GT98IW47aA=David R. Kovar41.78927490000000-87.60125000000000402Kovar, David R.ProfessorElenaDavydovaElena K. Davydova41.78927490000000-87.60125000000000454Davydova, ElenaJocelynMalamyJocelyn Malamy41.78927490000000-87.60125000000000735Malamy, JocelynAssociate ProfessorTobin R.Sosnickw3B6BLIbEO/5hHlsaUXv9Gq0+s+oTobin R. Sosnick41.78927490000000-87.60125000000000744Sosnick, Tobin R.Professor4.356350.00165404262research areas1.34780.0357243coauthor of40.78364.3241560similar to1168selected publicationstrue1true1ProfessorProfessortrue1ProfessorProfessortrue1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professortrue1ProfessorProfessortrue1Professor Professor true1Professor EmeritusProfessor Emeritustrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Assistant ProfessorAssistant ProfessorAuthorship 71334124272941Rothman-Denes LBProceedings of the National Academy of Sciences of the United States of AmericaStructure of Escherichia coli RNA polymerase holoenzyme at last. Proc Natl Acad Sci U S A. 2013 Dec 03; 110(49):19662-3.Proc Natl Acad Sci U S A2013-11-22T00:00:002013Structure of Escherichia coli RNA polymerase holoenzyme at last.1010Authorship 80143225924224Lenneman BR, Rothman-Denes LBBiomoleculesStructural and biochemical investigation of bacteriophage N4-encoded RNA polymerases. Biomolecules. 2015 Apr 27; 5(2):647-67.Biomolecules2015-04-27T00:00:002015Structural and biochemical investigation of bacteriophage N4-encoded RNA polymerases.Pediatrics-NeurologyChicago60637IL