25143596Fanning SW, Walter R, Horn JRProtein engineering, design & selection : PEDSBinding Sites, Antibody; Models, Molecular; Protein Engineering; Recombinant Fusion Proteins; Single-Domain AntibodiesCell Surface Display Techniques; Crystallization; Mutation; Protein Binding; Protein Conformation; ThermodynamicsStructural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site. Protein Eng Des Sel. 2014 Oct; 27(10):391-7.Protein Eng Des Sel2014-08-20T00:00:002014Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site.prns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAuthorshipvivo:hasSubjectAreahas subject areaInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkedInformationResourcelinked information resourcerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptD001666Chemicals & Drugs23490.991187Binding Sites, AntibodyD008958Concepts & Ideas24512840.706947Models, MolecularD009154Physiology70239520.442648MutationD011485PhenomenaPhysiology42014540.739266Protein BindingD011487Concepts & Ideas1998810.79421Protein ConformationD013816Occupations953080.906268ThermodynamicsD015202Procedures691400.899155Protein EngineeringD061505Procedures7160.984846Cell Surface Display TechniquesD061905Chemicals & Drugs440.993279Single-Domain AntibodiesD003460Chemicals & DrugsPhenomena492060.938392CrystallizationD011993Chemicals & Drugs2485550.847892Recombinant Fusion ProteinsAuthorship 663590.256950.256951authors10.2511has subject area