RicardoLastraRicardo Lastra0.000000000000000.000000000000003226Lastra, RicardoGestational Trophoblastic DiseaseR.Dr. Lastra is a surgical pathologist and cytopathologist with subspecialty focus in gynecologic pathology.Associate Professorprns:coAuthorOfcoauthor ofprns:emailEncryptedemail addressprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:trainingAtOrganizationeducational organizationprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipvivo:degreeEarneddegree earnedDepartmentvivo:educationalTrainingeducation and trainingEducational Trainingvivo:freetextKeywordkeywordsvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:majorFieldmajor field of degreevivo:middleNamemiddle name or initialvivo:overviewoverviewvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 1008583Authorship 100275527513075McGregor SM, Schoolmeester JK, Lastra RRInternational journal of gynecological pathology : official journal of the International Society of Gynecological PathologistsCollision Signet-Ring Stromal Tumor and Steroid Cell Tumor of the Ovary: Report of the First Case. Int J Gynecol Pathol. 2017 May; 36(3):261-264.Int J Gynecol Pathol2017-05-01T00:00:002017Collision Signet-Ring Stromal Tumor and Steroid Cell Tumor of the Ovary: Report of the First Case.28264838Chiyoda T, Hart PC, Eckert MA, McGregor SM, Lastra RR, Hamamoto R, Nakamura Y, Yamada SD, Olopade OI, Lengyel E, Romero ILCancer prevention research (Philadelphia, Pa.)Loss of BRCA1 in the Cells of Origin of Ovarian Cancer Induces Glycolysis: A Window of Opportunity for Ovarian Cancer Chemoprevention. Cancer Prev Res (Phila). 2017 Apr; 10(4):255-266.Cancer Prev Res (Phila)2017-03-06T00:00:002017Loss of BRCA1 in the Cells of Origin of Ovarian Cancer Induces Glycolysis: A Window of Opportunity for Ovarian Cancer Chemoprevention.Authorship 103101628428441Kach J, Long TM, Selman P, Tonsing-Carter EY, Bacalao MA, Lastra RR, de Wet L, Comiskey S, Gillard M, VanOpstall C, West DC, Chan WC, Griend DV, Conzen SD, Szmulewitz RZMolecular cancer therapeuticsSelective Glucocorticoid Receptor Modulators (SGRMs) Delay Castrate-Resistant Prostate Cancer Growth. Mol Cancer Ther. 2017 08; 16(8):1680-1692.Mol Cancer Ther2017-04-20T00:00:002017Selective Glucocorticoid Receptor Modulators (SGRMs) Delay Castrate-Resistant Prostate Cancer Growth.Authorship 105715628456378Veneris JT, Darcy KM, Mhawech-Fauceglia P, Tian C, Lengyel E, Lastra RR, Pejovic T, Conzen SD, Fleming GFGynecologic oncologyHigh glucocorticoid receptor expression predicts short progression-free survival in ovarian cancer. Gynecol Oncol. 2017 07; 146(1):153-160.Gynecol Oncol2017-04-26T00:00:002017High glucocorticoid receptor expression predicts short progression-free survival in ovarian cancer.D002583Disorders962740.791444Uterine Cervical NeoplasmsD005833Disorders541070.885519Genital Neoplasms, FemaleJenniferBennettJennifer Bennett41.7886000000000087.598699999999993688Bennett, JenniferAssociate ProfessorObstetrics and GynecologyMedicine-Hematology/Oncology30212867Johnson DN, Cavallo AB, Uraizee I, Tanager K, Lastra RR, Antic T, Cipriani NAAmerican journal of clinical pathologyA Proposal for Separation of Nuclear Atypia and Architectural Atypia in Bethesda Category III (AUS/FLUS) Based on Differing Rates of Thyroid Malignancy. Am J Clin Pathol. 2019 01 01; 151(1):86-94.Am J Clin Pathol2019-01-01T00:00:002019A Proposal for Separation of Nuclear Atypia and Architectural Atypia in Bethesda Category III (AUS/FLUS) Based on Differing Rates of Thyroid Malignancy.Authorship 109123529257039Tran L, Antic T, Lastra RRInternational journal of gynecological pathology : official journal of the International Society of Gynecological PathologistsIncidental Gynecologic Tract Neoplasms in Women Undergoing Anterior Pelvic Exenteration for Urothelial Carcinoma. Int J Gynecol Pathol. 2019 Jan; 38(1):97-102.Int J Gynecol Pathol2019-01-01T00:00:002019Incidental Gynecologic Tract Neoplasms in Women Undergoing Anterior Pelvic Exenteration for Urothelial Carcinoma.29105363Johnson DN, Barroeta JE, Antic T, Lastra RRDiagnostic cytopathologyCytomorphologic features of metastatic endometrioid carcinoma by fine needle aspiration. Diagn Cytopathol. 2018 Feb; 46(2):105-110.Diagn Cytopathol2017-11-04T00:00:002017Cytomorphologic features of metastatic endometrioid carcinoma by fine needle aspiration.Authorship 1096064Authorship 109605330014022Cowan M, Suntum T, Olivas AD, Perpich M, Applebaum MA, Lastra RR, Yamada SDGynecologic oncology reportsSecond primary rhabdomyosarcoma of the uterine cervix presenting with synchronous ovarian Sertoli-Leydig cell tumor: An illustrative case of DICER1 syndrome. Gynecol Oncol Rep. 2018 Aug; 25:94-97.Gynecol Oncol Rep2018-06-15T00:00:002018Second primary rhabdomyosarcoma of the uterine cervix presenting with synchronous ovarian Sertoli-Leydig cell tumor: An illustrative case of DICER1 syndrome.Authorship 1098796Authorship 11255513Authorship 1150574Authorship 1200618Authorship 1214845Authorship 1209554Authorship 1218834Authorship 1245056Authorship 125315530480644McGregor SM, Furtado LV, Montag AG, Brooks R, Lastra RRInternational journal of gynecological pathology : official journal of the International Society of Gynecological PathologistsEpithelioid Trophoblastic Tumor: Expanding the Clinicopathologic Spectrum of a Rare Malignancy. Int J Gynecol Pathol. 2020 Jan; 39(1):8-18.Int J Gynecol Pathol2020-01-01T00:00:002020Epithelioid Trophoblastic Tumor: Expanding the Clinicopathologic Spectrum of a Rare Malignancy.29687293Johnson MB, Hoffmann JN, You HM, Lastra RR, Fernandez S, Strober JW, Allaw AB, Brady MJ, Conzen SD, McClintock MKJournal of mammary gland biology and neoplasiaPsychosocial Stress Exposure Disrupts Mammary Gland Development. J Mammary Gland Biol Neoplasia. 2018 06; 23(1-2):59-73.J Mammary Gland Biol Neoplasia2018-04-23T00:00:002018Psychosocial Stress Exposure Disrupts Mammary Gland Development.28863071Chapel DB, Joseph NM, Krausz T, Lastra RRInternational journal of gynecological pathology : official journal of the International Society of Gynecological PathologistsAn Ovarian Adenocarcinoma With Combined Low-grade Serous and Mesonephric Morphologies Suggests a Müllerian Origin for Some Mesonephric Carcinomas. Int J Gynecol Pathol. 2018 Sep; 37(5):448-459.Int J Gynecol Pathol2018-09-01T00:00:002018An Ovarian Adenocarcinoma With Combined Low-grade Serous and Mesonephric Morphologies Suggests a Müllerian Origin for Some Mesonephric Carcinomas.29513076Lwanga A, Kamson DO, Wilkins TE, Sharma V, Schulte JJ, Miller J, Hassan I, Lastra RRThe neuroradiology journalOccult teratoma in a case of N-methyl-D-aspartate receptor encephalitis. Neuroradiol J. 2018 Aug; 31(4):415-419.Neuroradiol J2018-03-07T00:00:002018Occult teratoma in a case of N-methyl-D-aspartate receptor encephalitis.30174305Curtis M, Kenny HA, Ashcroft B, Mukherjee A, Johnson A, Zhang Y, Helou Y, Batlle R, Liu X, Gutierrez N, Gao X, Yamada SD, Lastra R, Montag A, Ahsan N, Locasale JW, Salomon AR, Nebreda AR, Lengyel ECell metabolismFibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis. Cell Metab. 2019 01 08; 29(1):141-155.e9.Cell Metab2018-08-30T00:00:002018Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis.29620587Chapel DB, Choy B, Pytel P, Husain AN, Lastra RRInternational journal of gynecological pathology : official journal of the International Society of Gynecological PathologistsMucolipidosis Type II Affecting 1 Fetus and Placental Disk of a Dichorionic-Diamnionic Twin Gestation: A Case Report and Review of the Literature. Int J Gynecol Pathol. 2019 Jul; 38(4):346-352.Int J Gynecol Pathol2019-07-01T00:00:002019Mucolipidosis Type II Affecting 1 Fetus and Placental Disk of a Dichorionic-Diamnionic Twin Gestation: A Case Report and Review of the Literature.29636357West DC, Kocherginsky M, Tonsing-Carter EY, Dolcen DN, Hosfield DJ, Lastra RR, Sinnwell JP, Thompson KJ, Bowie KR, Harkless RV, Skor MN, Pierce CF, Styke SC, Kim CR, de Wet L, Greene GL, Boughey JC, Goetz MP, Kalari KR, Wang L, Fleming GF, Györffy B, Conzen SDClinical cancer research : an official journal of the American Association for Cancer ResearchDiscovery of a Glucocorticoid Receptor (GR) Activity Signature Using Selective GR Antagonism in ER-Negative Breast Cancer. Clin Cancer Res. 2018 07 15; 24(14):3433-3446.Clin Cancer Res2018-04-10T00:00:002018Discovery of a Glucocorticoid Receptor (GR) Activity Signature Using Selective GR Antagonism in ER-Negative Breast Cancer.29656794Chapel DB, Yamada SD, Cowan M, Lastra RRGynecologic oncologyImmunohistochemistry for mismatch repair protein deficiency in endometrioid endometrial carcinoma yields equivalent results when performed on endometrial biopsy/curettage or hysterectomy specimens. Gynecol Oncol. 2018 06; 149(3):570-574.Gynecol Oncol2018-04-13T00:00:002018Immunohistochemistry for mismatch repair protein deficiency in endometrioid endometrial carcinoma yields equivalent results when performed on endometrial biopsy/curettage or hysterectomy specimens.Authorship 126649830655321Hart PC, Chiyoda T, Liu X, Weigert M, Curtis M, Chiang CY, Loth R, Lastra R, McGregor SM, Locasale JW, Lengyel E, Romero ILMolecular cancer research : MCRSPHK1 Is a Novel Target of Metformin in Ovarian Cancer. Mol Cancer Res. 2019 04; 17(4):870-881.Mol Cancer Res2019-01-17T00:00:002019SPHK1 Is a Novel Target of Metformin in Ovarian Cancer.2005Universidad Central de VenezuelaUniversidad Central de Venezuela, MD2012Pennsylvania HospitalPennsylvania Hospital, Anatomic and Clinical PathologyResidencyAnatomic and Clinical Pathology2013Hospital of the University of PennsylvaniaHospital of the University of Pennsylvania, Surgical Pathology FellowshipSurgical Pathology 2014Hospital of the University of PennsylvaniaHospital of the University of Pennsylvania, Cytopathology FellowshipCytopathology 2015The Johns Hopkins HospitalThe Johns Hopkins Hospital, Gynecologic PathologyAdvanced Specialty Training ProgramGynecologic PathologyAuthorship 1279834Authorship 1282154Authorship 128013530807370Chapel DB, Lengyel E, Ritterhouse LL, Lastra RRInternational journal of gynecological pathology : official journal of the International Society of Gynecological PathologistsInterpretation of Mismatch Repair Protein Immunohistochemistry in Endometrial Carcinoma Should Consider Both Lynch Syndrome Screening and Immunotherapy Susceptibility: An Illustrative Case Report. Int J Gynecol Pathol. 2020 May; 39(3):233-237.Int J Gynecol Pathol2020-05-01T00:00:002020Interpretation of Mismatch Repair Protein Immunohistochemistry in Endometrial Carcinoma Should Consider Both Lynch Syndrome Screening and Immunotherapy Susceptibility: An Illustrative Case Report.30775324Fidai SS, Sharma AE, Johnson DN, Segal JP, Lastra RRAutopsy & case reportsDihydropyrimidine dehydrogenase deficiency as a cause of fatal 5-Fluorouracil toxicity. Autops Case Rep. 2018 Oct-Dec; 8(4):e2018049.Autops Case Rep2018-11-30T00:00:002018Dihydropyrimidine dehydrogenase deficiency as a cause of fatal 5-Fluorouracil toxicity.30794347Choy B, Venkataraman G, Biernacka A, Lastra RR, Mueller J, Setia N, Reeves W, Antic TDiagnostic cytopathologyCorrelation of cytopathology with flow cytometry and histopathology for the diagnosis of hematologic malignancies in young adults presenting with cervical lymphadenopathy. Diagn Cytopathol. 2019 Jun; 47(6):579-583.Diagn Cytopathol2019-02-22T00:00:002019Correlation of cytopathology with flow cytometry and histopathology for the diagnosis of hematologic malignancies in young adults presenting with cervical lymphadenopathy.Authorship 128543330889579Olivas AD, Barroeta JE, Lastra RRActa cytologicaRole of Ancillary Techniques in Gynecologic Cytopathology Specimens. Acta Cytol. 2020; 64(1-2):63-70.Acta Cytol2019-03-19T00:00:002019Role of Ancillary Techniques in Gynecologic Cytopathology Specimens.Authorship 12927210Authorship 129312131043256Lastra RR, Birdsong G, Hwang DH, Jorda M, Kerr DA, McGrath C, Odronic S, Rao R, VanderLaan PA, Walker JW, Antic TJournal of the American Society of CytopathologyPreoperative cytologic interpretation of noninvasive follicular thyroid neoplasm with papillary-like nuclear features: a 1-year multi-institutional experience. J Am Soc Cytopathol. 2018 Mar - Apr; 7(2):79-85.J Am Soc Cytopathol2017-12-21T00:00:002017Preoperative cytologic interpretation of noninvasive follicular thyroid neoplasm with papillary-like nuclear features: a 1-year multi-institutional experience.31043742Eckert MA, Coscia F, Chryplewicz A, Chang JW, Hernandez KM, Pan S, Tienda SM, Nahotko DA, Li G, Blaženovic I, Lastra RR, Curtis M, Yamada SD, Perets R, McGregor SM, Andrade J, Fiehn O, Moellering RE, Mann M, Lengyel ENatureProteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts. Nature. 2019 05; 569(7758):723-728.Nature2019-05-01T00:00:002019Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts.Authorship 129470331074865Brooks RA, Fleming GF, Lastra RR, Lee NK, Moroney JW, Son CH, Tatebe K, Veneris JLCA: a cancer journal for cliniciansCurrent recommendations and recent progress in endometrial cancer. CA Cancer J Clin. 2019 07; 69(4):258-279.CA Cancer J Clin2019-05-10T00:00:002019Current recommendations and recent progress in endometrial cancer.31186530Chapel DB, Patil SA, Plagov A, Puranik R, Mendybaeva A, Steinhardt G, Wanjari P, Lastra RR, Kadri S, Segal JP, Ritterhouse LLModern pathology : an official journal of the United States and Canadian Academy of Pathology, IncQuantitative next-generation sequencing-based analysis indicates progressive accumulation of microsatellite instability between atypical hyperplasia/endometrial intraepithelial neoplasia and paired endometrioid endometrial carcinoma. Mod Pathol. 2019 10; 32(10):1508-1520.Mod Pathol2019-06-11T00:00:002019Quantitative next-generation sequencing-based analysis indicates progressive accumulation of microsatellite instability between atypical hyperplasia/endometrial intraepithelial neoplasia and paired endometrioid endometrial carcinoma.Authorship 1300468Authorship 1318821031340854Tonsing-Carter E, Hernandez KM, Kim CR, Harkless RV, Oh A, Bowie KR, West-Szymanski DC, Betancourt-Ponce MA, Green BD, Lastra RR, Fleming GF, Chandarlapaty S, Conzen SDBreast cancer research : BCRGlucocorticoid receptor modulation decreases ER-positive breast cancer cell proliferation and suppresses wild-type and mutant ER chromatin association. Breast Cancer Res. 2019 07 24; 21(1):82.Breast Cancer Res2019-07-24T00:00:002019Glucocorticoid receptor modulation decreases ER-positive breast cancer cell proliferation and suppresses wild-type and mutant ER chromatin association.D010051Disorders1667380.613506Ovarian NeoplasmsAuthorship 133481431591497Bennett JA, Ritterhouse LL, Furtado LV, Lastra RR, Pesci A, Newell JM, Burandt E, Kooreman L, Van de Vijver K, Krausz T, Felix A, Zannoni GF, Young RH, Oliva EModern pathology : an official journal of the United States and Canadian Academy of Pathology, IncFemale adnexal tumors of probable Wolffian origin: morphological, immunohistochemical, and molecular analysis of 15 cases. Mod Pathol. 2020 04; 33(4):734-747.Mod Pathol2019-10-07T00:00:002019Female adnexal tumors of probable Wolffian origin: morphological, immunohistochemical, and molecular analysis of 15 cases.Authorship 134703731830290Kanabolo D, Rodriguez J, Waggoner D, Tucker S, Deplewski D, Kaumeyer B, Lastra RR, Gundeti MPediatric annalsA Phenotypic Female Adolescent with Primary Amenorrhea and Dysmorphic Features. Pediatr Ann. 2019 Dec 01; 48(12):e495-e500.Pediatr Ann2019-12-01T00:00:002019A Phenotypic Female Adolescent with Primary Amenorrhea and Dysmorphic Features.Authorship 135464631985579Sharma AE, Hamedani FS, Barroeta JE, Pytel P, Bennett JA, Lastra RRInternational journal of gynecological pathology : official journal of the International Society of Gynecological PathologistsClear Cell Papillary Cystadenoma of the Ovary Masquerading as Metastatic Clear Cell Renal Cell Carcinoma: A Case Report and Review of the Literature. Int J Gynecol Pathol. 2021 May 01; 40(3):290-295.Int J Gynecol Pathol2021-05-01T00:00:002021Clear Cell Papillary Cystadenoma of the Ovary Masquerading as Metastatic Clear Cell Renal Cell Carcinoma: A Case Report and Review of the Literature.Authorship 135793632054768Mukherjee A, Chiang CY, Daifotis HA, Nieman KM, Fahrmann JF, Lastra RR, Romero IL, Fiehn O, Lengyel ECancer researchAdipocyte-Induced FABP4 Expression in Ovarian Cancer Cells Promotes Metastasis and Mediates Carboplatin Resistance. Cancer Res. 2020 04 15; 80(8):1748-1761.Cancer Res2020-02-13T00:00:002020Adipocyte-Induced FABP4 Expression in Ovarian Cancer Cells Promotes Metastasis and Mediates Carboplatin Resistance.Authorship 139234232675660Bennett JA, Lastra RR, Barroeta JE, Parilla M, Galbo F, Wanjari P, Young RH, Krausz T, Oliva EThe American journal of surgical pathologyUterine Tumor Resembling Ovarian Sex Cord Stromal Tumor (UTROSCT): A Series of 3 Cases With Extensive Rhabdoid Differentiation, Malignant Behavior, and ESR1-NCOA2 Fusions. Am J Surg Pathol. 2020 11; 44(11):1563-1572.Am J Surg Pathol2020-11-01T00:00:002020Uterine Tumor Resembling Ovarian Sex Cord Stromal Tumor (UTROSCT): A Series of 3 Cases With Extensive Rhabdoid Differentiation, Malignant Behavior, and ESR1-NCOA2 Fusions.AymanAl-HendyAyman Al-Hendy41.7886000000000087.598699999999993954Al-Hendy, AymanProfessorAuthorship 140729432897960Bennett JA, Safdar N, Segal JP, Lastra RR, Oliva EInternational journal of gynecological pathology : official journal of the International Society of Gynecological PathologistsEvaluation of SWI/SNF Protein Expression by Immunohistochemistry in Ovarian Clear Cell Carcinoma. Int J Gynecol Pathol. 2021 Mar 01; 40(2):156-164.Int J Gynecol Pathol2021-03-01T00:00:002021Evaluation of SWI/SNF Protein Expression by Immunohistochemistry in Ovarian Clear Cell Carcinoma.KathleenBeavisKathleen Beavis0.000000000000000.000000000000002879Beavis, KathleenProfessorJeremySegalJeremy Segal0.000000000000000.000000000000002880Segal, JeremyProfessorElieRichaElie Richa0.000000000000000.000000000000003060Richa, ElieAsst Prof-Clinical DeptMedicine-Hematology and OncologyObstetrics and Gynecology-Gynecologic OncologyAuthorship 143979333535202Chen HI, Lapadat R, Lastra RR, Biernacka A, Reeves W, Mueller J, Pambuccian SE, Barkan GA, Wojcik EM, Antic TActa cytologicaAccuracy of Subclassification and Grading of Renal Tumors on Fine Needle Aspiration Cytology Alone. Acta Cytol. 2021; 65(2):140-149.Acta Cytol2021-02-03T00:00:002021Accuracy of Subclassification and Grading of Renal Tumors on Fine Needle Aspiration Cytology Alone.Authorship 145650233833085Jani I, Lastra RR, Brito KS, Liao C, Lazo I, Lee NK, Yamada SD, Kurnit KCInternational journal of gynecological cancer : official journal of the International Gynecological Cancer SocietyChemotherapy response score as a prognostic tool in patients with advanced stage endometrial carcinoma treated with neoadjuvant chemotherapy. Int J Gynecol Cancer. 2021 06; 31(6):852-858.Int J Gynecol Cancer2021-04-08T00:00:002021Chemotherapy response score as a prognostic tool in patients with advanced stage endometrial carcinoma treated with neoadjuvant chemotherapy.Authorship 145978533867311Johnson DN, Antic T, Reeves W, Mueller J, Lastra RR, Cipriani NA, Biernacka AJournal of the American Society of CytopathologyHistopathologic and clinical outcomes of Milan System categories "non-diagnostic" and "non-neoplastic" of salivary gland fine needle aspirations. J Am Soc Cytopathol. 2021 Jul-Aug; 10(4):349-356.J Am Soc Cytopathol2021-03-19T00:00:002021Histopathologic and clinical outcomes of Milan System categories "non-diagnostic" and "non-neoplastic" of salivary gland fine needle aspirations.D016889Disorders641910.802339Endometrial NeoplasmsD018269Disorders23430.94136Carcinoma, EndometrioidAuthorship 150142234570968Turashvili G, Lastra RJournal of pathology and translational medicineWhat's new in gynecologic pathology 2021: ovary and fallopian tube. J Pathol Transl Med. 2021 Sep; 55(5):366-367.J Pathol Transl Med2021-09-15T00:00:002021What's new in gynecologic pathology 2021: ovary and fallopian tube.Authorship 1509061234737212Javellana M, Eckert MA, Heide J, Zawieracz K, Weigert M, Ashley S, Stock E, Chapel D, Huang L, Yamada SD, Ahmed AA, Lastra RR, Chen M, Lengyel ECancer researchNeoadjuvant Chemotherapy Induces Genomic and Transcriptomic Changes in Ovarian Cancer. Cancer Res. 2022 01 01; 82(1):169-176.Cancer Res2021-11-04T00:00:002021Neoadjuvant Chemotherapy Induces Genomic and Transcriptomic Changes in Ovarian Cancer.Authorship 152277235059489Asom AS, Lastra RR, Hasan Y, Weinberg L, Fleming GF, Kurnit KCGynecologic oncology reportsSmall cell carcinoma of the ovary, pulmonary type: A role for adjuvant radiotherapy after carboplatin and etoposide? Gynecol Oncol Rep. 2022 Feb; 39:100925.Gynecol Oncol Rep2022-01-07T00:00:002022Small cell carcinoma of the ovary, pulmonary type: A role for adjuvant radiotherapy after carboplatin and etoposide?Authorship 1525623Authorship 152591535121810Chapel DB, Sharma A, Lastra RR, Maccio L, Bragantini E, Zannoni GF, George S, Quade BJ, Parra-Herran C, Nucci MRModern pathology : an official journal of the United States and Canadian Academy of Pathology, IncA novel morphology-based risk stratification model for stage I uterine leiomyosarcoma: an analysis of 203 cases. Mod Pathol. 2022 06; 35(6):794-807.Mod Pathol2022-02-04T00:00:002022A novel morphology-based risk stratification model for stage I uterine leiomyosarcoma: an analysis of 203 cases.35125405Sharma AE, Moran A, Somasegar S, Steinhardt G, Chapel DB, Lastra RR, Lee NK, Ritterhouse LL, Bennett JAInternational journal of gynecological pathology : official journal of the International Society of Gynecological PathologistsClinicopathologic Evaluation and Molecular Profiling of Recurrent Stage IA Endometrial Endometrioid Carcinoma: A Case-control Study. Int J Gynecol Pathol. 2022 Feb 04.Int J Gynecol Pathol2022-02-04T00:00:002022Clinicopathologic Evaluation and Molecular Profiling of Recurrent Stage IA Endometrial Endometrioid Carcinoma: A Case-control Study.Authorship 153164435195717Carll T, Fuja C, Antic T, Lastra R, Pytel PAmerican journal of clinical pathologyTissue Contamination During Transportation of Formalin-Fixed, Paraffin-Embedded Blocks. Am J Clin Pathol. 2022 07 01; 158(1):96-104.Am J Clin Pathol2022-07-01T00:00:002022Tissue Contamination During Transportation of Formalin-Fixed, Paraffin-Embedded Blocks.Authorship 154534335519002Kurnit KC, Steiner M, Lastra RR, Weroha SJ, Cursio J, Lengyel E, Fleming GF, Conzen SDGynecologic oncology reportsHigh glucocorticoid receptor expression in the sarcomatous versus carcinomatous elements of Mullerian carcinosarcomas. Gynecol Oncol Rep. 2022 Jun; 41:100987.Gynecol Oncol Rep2022-04-27T00:00:002022High glucocorticoid receptor expression in the sarcomatous versus carcinomatous elements of Mullerian carcinosarcomas.Authorship 156377535883603Yang Q, Bariani MV, Falahati A, Khosh A, Lastra RR, Siblini H, Boyer TG, Al-Hendy ACellsThe Functional Role and Regulatory Mechanism of Bromodomain-Containing Protein 9 in Human Uterine Leiomyosarcoma. Cells. 2022 07 10; 11(14).Cells2022-07-10T00:00:002022The Functional Role and Regulatory Mechanism of Bromodomain-Containing Protein 9 in Human Uterine Leiomyosarcoma.AndreaOlivasAndrea Olivas41.7886000000000087.598699999999994258Olivas, AndreaAssistant ProfessorAuthorship 1587919Authorship 15898714Authorship 1593842Authorship 1591423Authorship 159159236044323Tran L, Christensen P, Barroeta JE, Hunter K, Sookram J, McGregor SM, Wilkinson N, Orsi NM, Lastra RRInternational journal of gynecological pathology : official journal of the International Society of Gynecological PathologistsPrognostic Significance of Size, Location, and Number of Lymph Node Metastases in Endometrial Carcinoma. Int J Gynecol Pathol. 2023 Jul 01; 42(4):376-389.Int J Gynecol Pathol2022-08-09T00:00:002022Prognostic Significance of Size, Location, and Number of Lymph Node Metastases in Endometrial Carcinoma.36572015Mendoza RP, Lastra RRActa cytologicaPractical Approach to the Evaluation of Malignant Peritoneal Fluids in the Setting of Gynecologic Neoplasms. Acta Cytol. 2023; 67(2):143-175.Acta Cytol2022-12-26T00:00:002022Practical Approach to the Evaluation of Malignant Peritoneal Fluids in the Setting of Gynecologic Neoplasms.36599328Olivas AD, Barroeta JE, Lastra RRActa cytologicaOverview of Ancillary Techniques in Cervical Cytology. Acta Cytol. 2023; 67(2):119-128.Acta Cytol2023-01-04T00:00:002023Overview of Ancillary Techniques in Cervical Cytology.36603562Barroeta JE, Lastra RRActa cytologicaCytopathology in Gynecology and Gynecologic Oncology: Updates, Recent Advances, and Practical Considerations. Acta Cytol. 2023; 67(2):109-110.Acta Cytol2023-01-05T00:00:002023Cytopathology in Gynecology and Gynecologic Oncology: Updates, Recent Advances, and Practical Considerations.36543131Lengyel E, Li Y, Weigert M, Zhu L, Eckart H, Javellana M, Ackroyd S, Xiao J, Olalekan S, Glass D, Iyer S, Krishnan R, Bilecz AJ, Lastra R, Chen M, Basu ACell reportsA molecular atlas of the human postmenopausal fallopian tube and ovary from single-cell RNA and ATAC sequencing. Cell Rep. 2022 12 20; 41(12):111838.Cell Rep2022-12-20T00:00:002022A molecular atlas of the human postmenopausal fallopian tube and ovary from single-cell RNA and ATAC sequencing.Authorship 161027436795484Bajwa P, Kordylewicz K, Bilecz A, Lastra RR, Wroblewski K, Rinkevich Y, Lengyel E, Kenny HAJCI insightCancer-associated mesothelial cell-derived ANGPTL4 and STC1 promote the early steps of ovarian cancer metastasis. JCI Insight. 2023 03 22; 8(6).JCI Insight2023-03-22T00:00:002023Cancer-associated mesothelial cell-derived ANGPTL4 and STC1 promote the early steps of ovarian cancer metastasis.Authorship 161180636819804Laberiano-Fernández C, Luján JM, de Carvalho Dornelas B, Benites MF, Quispe PG, Vásquez VA, Espinoza AG, Guerra EG, Álvarez GG, Astigueta-Pérez J, de Dávila MTG, Zambrano SC, Rojas TV, Mariños A, González ES, Lazcano R, Lastra RR, Alvarado-Cabrero I, Miller HG, Bardales RH, Abad-Licham MEcancermedicalscienceHighlights from the 7th Oncological Pathology Conference 'Pathological Anatomy in the context of the National Cancer Law: An overview of the Latin American experience', 15, 22 and 23 July 2022, Trujillo, Peru. Ecancermedicalscience. 2022; 16:1462.Ecancermedicalscience2022-11-02T00:00:002022Highlights from the 7th Oncological Pathology Conference 'Pathological Anatomy in the context of the National Cancer Law: An overview of the Latin American experience', 15, 22 and 23 July 2022, Trujillo, Peru.https://obgyn.uchicago.edu/page/section-gynecologic-oncologyGynecologic Oncology Section - Univ. of Chicagohttps://obgyn.uchicago.edu/Univ. of Chicago OB&GYNhttp://obg.bsd.uchicago.edu/FacultyResearch/lengyellab.htmOvarian Cancer Laboratory in Chicagohttps://www.uchicagomedicine.org/find-a-physician/physician/ernst-lengyelClinical Profilehttps://www.uchicagomedicine.org/conditions-services/obgyn/specialtyOB&GYN Clinical Patient information37046379Elmuti L, Amundson J, Oberman E, Kamat A, Sedig L, Lastra RR, Aldape K, Quezado M, Pratt DW, Cimino PJ, Abdullaev Z, Pytel P, Applebaum MA, Bennett JAInternational journal of gynecological pathology : official journal of the International Society of Gynecological PathologistsDiffuse Pediatric-type High-grade Glioma Arising in an Ovarian Mature Cystic Teratoma. Int J Gynecol Pathol. 2024 Jan 01; 43(1):90-96.Int J Gynecol Pathol2023-04-13T00:00:002023Diffuse Pediatric-type High-grade Glioma Arising in an Ovarian Mature Cystic Teratoma.Authorship 1619266MedicinePathologyUniversity of Chicago37702216Stolnicu S, Allison D, Praiss AM, Tessier-Cloutier B, Momeni Boroujeni A, Flynn J, Iasonos A, Serrette R, Hoang L, Patrichi A, Terinte C, Pesci A, Mateoiu C, Lastra RR, Kiyokawa T, Ali-Fehmi R, Kheil M, Oliva E, Devins KM, Abu-Rustum NR, Soslow RAThe American journal of surgical pathologyIncidence and Clinicopathologic Characteristics of Human Papillomavirus-independent Invasive Squamous Cell Carcinomas of the Cervix: A Morphologic, Immunohistochemical, and Human Papilloma-Virologic Study of 670 Cases. Am J Surg Pathol. 2023 12 01; 47(12):1376-1389.Am J Surg Pathol2023-09-13T00:00:002023Incidence and Clinicopathologic Characteristics of Human Papillomavirus-independent Invasive Squamous Cell Carcinomas of the Cervix: A Morphologic, Immunohistochemical, and Human Papilloma-Virologic Study of 670 Cases.37541128Praiss AM, Allison D, Tessier-Cloutier B, Flynn J, Iasonos A, Hoang L, Patrichi A, Terinte C, Pesci A, Mateoiu C, Lastra RR, Puscasiu L, Kiyokawa T, Ali-Fehmi R, Kheil M, Oliva E, Devins KM, Abu-Rustum NR, Soslow RA, Stolnicu SGynecologic oncologyExtensive versus focal lymphovascular invasion in squamous cell carcinoma of the cervix: A comprehensive international, multicenter, retrospective clinicopathologic study. Gynecol Oncol. 2023 09; 176:147-154.Gynecol Oncol2023-08-02T00:00:002023Extensive versus focal lymphovascular invasion in squamous cell carcinoma of the cervix: A comprehensive international, multicenter, retrospective clinicopathologic study.Authorship 16599711Authorship 16625914TatjanaAnticTatjana Antic41.78927490000000-87.601250000000001672Antic, TatjanaProfessorGiniFleming0GRlDqwcF+v5hHlsaUXv9Gq0+s+oGini Fleming41.78927490000000-87.601250000000001804Fleming, GiniProfessorErnst RobertLengyel0m5sBaYMHOD5hHlsaUXv9Gq0+s+oErnst Robert Lengyel41.78927490000000-87.601250000000001942Lengyel, Ernst RobertProfessorYusukeNakamuraYusuke Nakamura41.78927490000000-87.60125000000000582Nakamura, YusukeEmeritus/Emerita, ProfessorSuzanneConzenSuzanne D. Conzen41.78927490000000-87.60125000000000599Conzen, SuzanneProfessorAuthorship 16836621Authorship 168512938014221Schweizer L, Krishnan R, Shimizu A, Metousis A, Kenny H, Mendoza R, Nordmann TM, Rauch S, Kelliher L, Heide J, Rosenberger FA, Bilecz A, Borrego SN, Strauss MT, Thielert M, Rodriguez E, Müller-Reif JB, Chen M, Yamada SD, Mund A, Lastra RR, Mann M, Lengyel EmedRxiv : the preprint server for health sciencesSpatial proteo-transcriptomic profiling reveals the molecular landscape of borderline ovarian tumors and their invasive progression. medRxiv. 2023 Nov 13.medRxiv2023-11-13T00:00:002023Spatial proteo-transcriptomic profiling reveals the molecular landscape of borderline ovarian tumors and their invasive progression.38030378Bennett L, Jaiswal PK, Harkless RV, Long TM, Gao N, Vandenburg B, Selman P, Durdana I, Lastra RR, Vander Griend D, Adelaiye-Ogala R, Szmulewitz RZ, Conzen SDMolecular cancer therapeuticsGlucocorticoid receptor (GR) activation is associated with increased cAMP/PKA signaling in castrate-resistant prostate cancer. Mol Cancer Ther. 2023 Nov 30.Mol Cancer Ther2023-11-30T00:00:002023Glucocorticoid receptor (GR) activation is associated with increased cAMP/PKA signaling in castrate-resistant prostate cancer.Authorship 1690291138085957Stolnicu S, Praiss AM, Allison D, Tessier-Cloutier B, Flynn J, Iasonos A, Hoang L, Terinte C, Pesci A, Mateoiu C, Lastra RR, Kiyokawa T, Ali-Fehmi R, Kheil M, Oliva E, Devins K, Abu-Rustum N, Soslow RAInternational journal of gynecological pathology : official journal of the International Society of Gynecological PathologistsProposal of Novel Binary Grading Systems for Cervical Squamous Cell Carcinoma. Int J Gynecol Pathol. 2023 Nov 09.Int J Gynecol Pathol2023-11-09T00:00:002023Proposal of Novel Binary Grading Systems for Cervical Squamous Cell Carcinoma.Authorship 1709173Authorship 170949838462794Rau TT, Cross W, Lastra RR, Lo RC, Matoso A, Herrington CSThe journal of pathology. Clinical researchClosing the loop - the role of pathologists in digital and computational pathology research. J Pathol Clin Res. 2024 Mar; 10(2):e12366.J Pathol Clin Res2024-03-01T00:00:002024Closing the loop - the role of pathologists in digital and computational pathology research.38484495Mendoza RP, Doytcheva K, Ud Dean M, Jorgenson KM, Choi D, Segal J, Wang P, Lastra RRPlacentaWhole exome sequencing of placental chorangioma. Placenta. 2024 Mar 08; 149:13-17.Placenta2024-03-08T00:00:002024Whole exome sequencing of placental chorangioma.true1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Associate ProfessorAssociate Professortrue1Asst Prof-Clinical DeptAsst Prof-Clinical Depttrue1Assistant ProfessorAssistant Professortrue1Associate ProfessorAssociate Professor1010Chicago60637ILNamrataSetiaNamrata Setia0.000000000000000.000000000000003201Setia, NamrataAssociate Professor4.083480.0190584329research areas1.665970.03723643coauthor of92.556214.837760similar to1175selected publicationsAuthorship 823771Authorship 824272Authorship 818691Authorship 823092Authorship 818271Authorship 819701Authorship 819981Authorship 820071Authorship 824725Authorship 82531124793239Motz GT, Santoro SP, Wang LP, Garrabrant T, Lastra RR, Hagemann IS, Lal P, Feldman MD, Benencia F, Coukos GNature medicineTumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors. Nat Med. 2014 Jun; 20(6):607-15.Nat Med2014-05-04T00:00:002014Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors.23904388Lastra RR, Ou JJ, Reilly ME, Lawrence WD, Baloch ZW, Brooks JS, Barroeta JEDiagnostic cytopathologyUtility of ProExC and IMP3 immunocytochemical staining in atypical glandular cells of undetermined significance in liquid-based cervical cytology. Diagn Cytopathol. 2014 May; 42(5):375-9.Diagn Cytopathol2013-08-01T00:00:002013Utility of ProExC and IMP3 immunocytochemical staining in atypical glandular cells of undetermined significance in liquid-based cervical cytology.21903680Ferenczi K, Lastra RR, Farkas T, Elenitsas R, Xu X, Roberts S, Brooks JS, Zhang PJInternational journal of surgical pathologyMUM-1 expression differentiates tumors in the PEComa family from clear cell sarcoma and melanoma. Int J Surg Pathol. 2012 Feb; 20(1):29-36.Int J Surg Pathol2011-09-08T00:00:002011MUM-1 expression differentiates tumors in the PEComa family from clear cell sarcoma and melanoma.26009539Schoolmeester JK, Lastra RRHuman pathologyGranular cell tumors overexpress TFE3 without corollary gene rearrangement. Hum Pathol. 2015 Aug; 46(8):1242-3.Hum Pathol2015-04-21T00:00:002015Granular cell tumors overexpress TFE3 without corollary gene rearrangement.25123499Lastra RR, Pramick MR, Crammer CJ, LiVolsi VA, Baloch ZWCancer cytopathologyImplications of a suspicious afirma test result in thyroid fine-needle aspiration cytology: an institutional experience. Cancer Cytopathol. 2014 Oct; 122(10):737-44.Cancer Cytopathol2014-08-13T00:00:002014Implications of a suspicious afirma test result in thyroid fine-needle aspiration cytology: an institutional experience.22317879Lastra RR, Bavuso N, Randall TC, Brooks JS, Barroeta JEInternational journal of gynecological pathology : official journal of the International Society of Gynecological PathologistsNeurofibroma of the cervix presenting as cervical stenosis in a patient with neurofibromatosis type 1: a case report. Int J Gynecol Pathol. 2012 Mar; 31(2):192-194.Int J Gynecol Pathol2012-03-01T00:00:002012Neurofibroma of the cervix presenting as cervical stenosis in a patient with neurofibromatosis type 1: a case report.20229119Lastra RR, Saldanha V, Balasubramanian M, Handal JEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research SocietyFatal fat embolism in isolated vertebral compression fracture. Eur Spine J. 2010 Jul; 19 Suppl 2:S200-2.Eur Spine J2010-03-13T00:00:002010Fatal fat embolism in isolated vertebral compression fracture.24932821Lastra RR, Newman JG, Brooks JS, Huang JHEar, nose, & throat journalOssifying fibromyxoid tumor metastatic to the thyroid: a case report and review of the literature. Ear Nose Throat J. 2014 Jun; 93(6):221-3.Ear Nose Throat J2014-06-01T00:00:002014Ossifying fibromyxoid tumor metastatic to the thyroid: a case report and review of the literature.24403949Lastra RR, Pramick MR, Nakashima MO, Weinstein GS, Montone KT, Livolsi VA, Baloch ZWCytoJournalAdequacy of fine-needle aspiration specimens for human papillomavirus infection molecular testing in head and neck squamous cell carcinoma. Cytojournal. 2013; 10:21.Cytojournal2013-10-29T00:00:002013Adequacy of fine-needle aspiration specimens for human papillomavirus infection molecular testing in head and neck squamous cell carcinoma.24664970Lastra RR, LiVolsi VA, Baloch ZWCancer cytopathologyAggressive variants of follicular cell-derived thyroid carcinomas: a cytopathologist's perspective. Cancer Cytopathol. 2014 Jul; 122(7):484-503.Cancer Cytopathol2014-03-24T00:00:002014Aggressive variants of follicular cell-derived thyroid carcinomas: a cytopathologist's perspective.Authorship 857223Authorship 85413126523540Lastra RR, Park KJ, Schoolmeester JKThe American journal of surgical pathologyInvasive Stratified Mucin-producing Carcinoma and Stratified Mucin-producing Intraepithelial Lesion (SMILE): 15 Cases Presenting a Spectrum of Cervical Neoplasia With Description of a Distinctive Variant of Invasive Adenocarcinoma. Am J Surg Pathol. 2016 Feb; 40(2):262-9.Am J Surg Pathol2016-02-01T00:00:002016Invasive Stratified Mucin-producing Carcinoma and Stratified Mucin-producing Intraepithelial Lesion (SMILE): 15 Cases Presenting a Spectrum of Cervical Neoplasia With Description of a Distinctive Variant of Invasive Adenocarcinoma.25123326Lastra RR, Meykler SE, Baloch ZW, Barroeta JECytopathology : official journal of the British Society for Clinical CytologyIncreasing the sensitivity of endocervical curettings by performing ThinPrep® Pap on transport container fluid: is diagnostic material going down the drain? Cytopathology. 2015 Dec; 26(6):368-72.Cytopathology2014-08-13T00:00:002014Increasing the sensitivity of endocervical curettings by performing ThinPrep® Pap on transport container fluid: is diagnostic material going down the drain?Authorship 92509727174588Parra-Herran C, Taljaard M, Djordjevic B, Reyes MC, Schwartz L, Schoolmeester JK, Lastra RR, Quick CM, Laury A, Rasty G, Nucci MR, Howitt BEModern pathology : an official journal of the United States and Canadian Academy of Pathology, IncPattern-based classification of invasive endocervical adenocarcinoma, depth of invasion measurement and distinction from adenocarcinoma in situ: interobserver variation among gynecologic pathologists. Mod Pathol. 2016 08; 29(8):879-92.Mod Pathol2016-05-13T00:00:002016Pattern-based classification of invasive endocervical adenocarcinoma, depth of invasion measurement and distinction from adenocarcinoma in situ: interobserver variation among gynecologic pathologists.27561551Coscia F, Watters KM, Curtis M, Eckert MA, Chiang CY, Tyanova S, Montag A, Lastra RR, Lengyel E, Mann MNature communicationsIntegrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status. Nat Commun. 2016 08 26; 7:12645.Nat Commun2016-08-26T00:00:002016Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status.Authorship 93666718416647Alvarez-Busto I, Alcedo J, Vera J, Borderias L, Ligorred L, Quiles D, Lastra R, Martínez Moya LRevista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva[Intestinal obstruction as early clinic manifestation of lung adenocarcinoma]. Rev Esp Enferm Dig. 2008 Mar; 100(3):180-2.Rev Esp Enferm Dig2008-03-01T00:00:002008[Intestinal obstruction as early clinic manifestation of lung adenocarcinoma].Jason X.Cheng3WN6BK9bGuTcn31EdUXm/Hbq9t+85aYQdX1vJason X. Cheng0.000000000000000.000000000000002798Cheng, Jason X.Associate ProfessorAuthorship 967619Authorship 97015827856443Eckert MA, Pan S, Hernandez KM, Loth RM, Andrade J, Volchenboum SL, Faber P, Montag A, Lastra R, Peter ME, Yamada SD, Lengyel ECancer discoveryGenomics of Ovarian Cancer Progression Reveals Diverse Metastatic Trajectories Including Intraepithelial Metastasis to the Fallopian Tube. Cancer Discov. 2016 12; 6(12):1342-1351.Cancer Discov2016-10-07T00:00:002016Genomics of Ovarian Cancer Progression Reveals Diverse Metastatic Trajectories Including Intraepithelial Metastasis to the Fallopian Tube.Authorship 97719227578056Schulte JJ, Lastra RRDiagnostic cytopathologyAbdominopelvic washings in gynecologic pathology: A comprehensive review. Diagn Cytopathol. 2016 Dec; 44(12):1039-1057.Diagn Cytopathol2016-08-30T00:00:002016Abdominopelvic washings in gynecologic pathology: A comprehensive review.