BenHallBen Hall0.000000000000000.000000000000002794Hall, BenA.plugins:TwitterTwitterprns:coAuthorOfcoauthor ofprns:emailEncryptedemail addressFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:middleNamemiddle name or initialvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD000230Disorders29111600.582251AdenocarcinomaAuthorship 101641224683369Wright DW, Hall BA, Kenway OA, Jha S, Coveney PVJournal of chemical theory and computationComputing Clinically Relevant Binding Free Energies of HIV-1 Protease Inhibitors. J Chem Theory Comput. 2014 Mar 11; 10(3):1228-1241.J Chem Theory Comput2014-01-27T00:00:002014Computing Clinically Relevant Binding Free Energies of HIV-1 Protease Inhibitors.Anesthesia and Critical CareBiochemistry and Molecular BiologyObstetrics and GynecologyRadiation and Cellular OncologyMedicine-Hematology/OncologyAuthorship 114775928954231Coats BR, Schoenfelt KQ, Barbosa-Lorenzi VC, Peris E, Cui C, Hoffman A, Zhou G, Fernandez S, Zhai L, Hall BA, Haka AS, Shah AM, Reardon CA, Brady MJ, Rhodes CJ, Maxfield FR, Becker LCell reportsMetabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity. Cell Rep. 2017 Sep 26; 20(13):3149-3161.Cell Rep2017-09-26T00:00:002017Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity.D009154Physiology70239520.442648MutationAuthorship 1320218Authorship 1321073Authorship 1320236Authorship 13212611Authorship 1320221031362624Hall MWJ, Jones PH, Hall BAJournal of the Royal Society, InterfaceRelating evolutionary selection and mutant clonal dynamics in normal epithelia. J R Soc Interface. 2019 07 26; 16(156):20190230.J R Soc Interface2019-07-26T00:00:002019Relating evolutionary selection and mutant clonal dynamics in normal epithelia.30269904Murai K, Skrupskelyte G, Piedrafita G, Hall M, Kostiou V, Ong SH, Nagy T, Cagan A, Goulding D, Klein AM, Hall BA, Jones PHCell stem cellEpidermal Tissue Adapts to Restrain Progenitors Carrying Clonal p53 Mutations. Cell Stem Cell. 2018 11 01; 23(5):687-699.e8.Cell Stem Cell2018-09-27T00:00:002018Epidermal Tissue Adapts to Restrain Progenitors Carrying Clonal p53 Mutations.30069015Shorthouse D, Riedel A, Kerr E, Pedro L, Bihary D, Samarajiwa S, Martins CP, Shields J, Hall BANature communicationsExploring the role of stromal osmoregulation in cancer and disease using executable modelling. Nat Commun. 2018 08 01; 9(1):3011.Nat Commun2018-08-01T00:00:002018Exploring the role of stromal osmoregulation in cancer and disease using executable modelling.28790158Turrell FK, Kerr EM, Gao M, Thorpe H, Doherty GJ, Cridge J, Shorthouse D, Speed A, Samarajiwa S, Hall BA, Griffiths M, Martins CPGenes & developmentLung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity. Genes Dev. 2017 07 01; 31(13):1339-1353.Genes Dev2017-07-01T00:00:002017Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity.29855020Paterson YZ, Shorthouse D, Pleijzier MW, Piterman N, Bendtsen C, Hall BA, Fisher JIntegrative biology : quantitative biosciences from nano to macroA toolbox for discrete modelling of cell signalling dynamics. Integr Biol (Camb). 2018 06 18; 10(6):370-382.Integr Biol (Camb)2018-06-18T00:00:002018A toolbox for discrete modelling of cell signalling dynamics.Authorship 134300231727818Nik-Zainal S, Hall BAScience (New York, N.Y.)Cellular survival over genomic perfection. Science. 2019 11 15; 366(6467):802-803.Science2019-11-15T00:00:002019Cellular survival over genomic perfection.D011506Chemicals & Drugs3127770.656392ProteinsAymanAl-HendyAyman Al-Hendy41.7886000000000087.598699999999993954Al-Hendy, AymanProfessorAuthorship 1399508Authorship 13990214Authorship 139949132188860Piedrafita G, Kostiou V, Wabik A, Colom B, Fernandez-Antoran D, Herms A, Murai K, Hall BA, Jones PHNature communicationsA single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice. Nat Commun. 2020 03 18; 11(1):1429.Nat Commun2020-03-18T00:00:002020A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice.32424351Colom B, Alcolea MP, Piedrafita G, Hall MWJ, Wabik A, Dentro SC, Fowler JC, Herms A, King C, Ong SH, Sood RK, Gerstung M, Martincorena I, Hall BA, Jones PHNature geneticsSpatial competition shapes the dynamic mutational landscape of normal esophageal epithelium. Nat Genet. 2020 06; 52(6):604-614.Nat Genet2020-05-18T00:00:002020Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium.32078258Hall BA, Fisher JCurrent protocols in bioinformaticsConstructing and Analyzing Computational Models of Cell Signaling with BioModelAnalyzer. Curr Protoc Bioinformatics. 2020 03; 69(1):e95.Curr Protoc Bioinformatics2020-03-01T00:00:002020Constructing and Analyzing Computational Models of Cell Signaling with BioModelAnalyzer.DemetArac-OzkanDemet Arac-Ozkan0.000000000000000.000000000000002885Arac-Ozkan, DemetAssociate ProfessorAuthorship 1416131933087317Fowler JC, King C, Bryant C, Hall MWJ, Sood R, Ong SH, Earp E, Fernandez-Antoran D, Koeppel J, Dentro SC, Shorthouse D, Durrani A, Fife K, Rytina E, Milne D, Roshan A, Mahububani K, Saeb-Parsy K, Hall BA, Gerstung M, Jones PHCancer discoverySelection of Oncogenic Mutant Clones in Normal Human Skin Varies with Body Site. Cancer Discov. 2021 02; 11(2):340-361.Cancer Discov2020-10-21T00:00:002020Selection of Oncogenic Mutant Clones in Normal Human Skin Varies with Body Site.Ben May Department of Cancer ResearchObstetrics and Gynecology-Family PlanningObstetrics and Gynecology-Gynecology and Minimally Invasive SurgeryAuthorship 145932333848143Shorthouse D, Hall MWJ, Hall BAJournal of chemical information and modelingComputational Saturation Screen Reveals the Landscape of Mutations in Human Fumarate Hydratase. J Chem Inf Model. 2021 04 26; 61(4):1970-1980.J Chem Inf Model2021-04-13T00:00:002021Computational Saturation Screen Reveals the Landscape of Mutations in Human Fumarate Hydratase.Authorship 146452433978741Lee M, Shorthouse D, Mahen R, Hall BA, Venkitaraman ARNucleic acids researchCancer-causing BRCA2 missense mutations disrupt an intracellular protein assembly mechanism to disable genome maintenance. Nucleic Acids Res. 2021 06 04; 49(10):5588-5604.Nucleic Acids Res2021-06-04T00:00:002021Cancer-causing BRCA2 missense mutations disrupt an intracellular protein assembly mechanism to disable genome maintenance.Authorship 146723534035949Kostiou V, Zhang H, Hall MWJ, Jones PH, Hall BARoyal Society open scienceMethods for analysing lineage tracing datasets. R Soc Open Sci. 2021 May 05; 8(5):202231.R Soc Open Sci2021-05-05T00:00:002021Methods for analysing lineage tracing datasets.22745242Gregg BE, Moore PC, Demozay D, Hall BA, Li M, Husain A, Wright AJ, Atkinson MA, Rhodes CJThe Journal of clinical endocrinology and metabolismFormation of a human ß-cell population within pancreatic islets is set early in life. J Clin Endocrinol Metab. 2012 Sep; 97(9):3197-206.J Clin Endocrinol Metab2012-06-28T00:00:002012Formation of a human ß-cell population within pancreatic islets is set early in life.Authorship 149561234472347Shorthouse D, Hall BAJournal of chemical information and modelingSARS-CoV-2 Variants Are Selecting for Spike Protein Mutations That Increase Protein Stability. J Chem Inf Model. 2021 09 27; 61(9):4152-4155.J Chem Inf Model2021-09-02T00:00:002021SARS-CoV-2 Variants Are Selecting for Spike Protein Mutations That Increase Protein Stability.22842983Hall BA, Kim TY, Skor MN, Conzen SDBreast cancer research and treatmentSerum and glucocorticoid-regulated kinase 1 (SGK1) activation in breast cancer: requirement for mTORC1 activity associates with ER-alpha expression. Breast Cancer Res Treat. 2012 Sep; 135(2):469-79.Breast Cancer Res Treat2012-07-29T00:00:002012Serum and glucocorticoid-regulated kinase 1 (SGK1) activation in breast cancer: requirement for mTORC1 activity associates with ER-alpha expression.Authorship 1503214Authorship 1504021534646013Colom B, Herms A, Hall MWJ, Dentro SC, King C, Sood RK, Alcolea MP, Piedrafita G, Fernandez-Antoran D, Ong SH, Fowler JC, Mahbubani KT, Saeb-Parsy K, Gerstung M, Hall BA, Jones PHNatureMutant clones in normal epithelium outcompete and eliminate emerging tumours. Nature. 2021 10; 598(7881):510-514.Nature2021-10-13T00:00:002021Mutant clones in normal epithelium outcompete and eliminate emerging tumours.34637643Kostiou V, Hall MWJ, Jones PH, Hall BAJournal of the Royal Society, InterfaceSimulations reveal that different responses to cell crowding determine the expansion of p53 and Notch mutant clones in squamous epithelia. J R Soc Interface. 2021 10; 18(183):20210607.J R Soc Interface2021-10-13T00:00:002021Simulations reveal that different responses to cell crowding determine the expansion of p53 and Notch mutant clones in squamous epithelia.Authorship 153845835362044Riedel A, Helal M, Pedro L, Swietlik JJ, Shorthouse D, Schmitz W, Haas L, Young T, da Costa ASH, Davidson S, Bhandare P, Wolf E, Hall BA, Frezza C, Oskarsson T, Shields JDCancer immunology researchTumor-Derived Lactic Acid Modulates Activation and Metabolic Status of Draining Lymph Node Stroma. Cancer Immunol Res. 2022 04 01; 10(4):482-497.Cancer Immunol Res2022-04-01T00:00:002022Tumor-Derived Lactic Acid Modulates Activation and Metabolic Status of Draining Lymph Node Stroma.Julia C.RosebushJulia C. Rosebush0.000000000000000.000000000000003081Rosebush, Julia C.Associate ProfessorAllisonDaltonAllison Dalton0.000000000000000.000000000000003114Dalton, AllisonAssociate ProfessorAuthorship 15961115Authorship 1599745Authorship 1588797Authorship 1592399Authorship 1600011236192425Talarmain L, Clarke MA, Shorthouse D, Cabrera-Cosme L, Kent DG, Fisher J, Hall BANature communicationsHOXA9 has the hallmarks of a biological switch with implications in blood cancers. Nat Commun. 2022 10 03; 13(1):5829.Nat Commun2022-10-03T00:00:002022HOXA9 has the hallmarks of a biological switch with implications in blood cancers.36175792Rahrmann EP, Shorthouse D, Jassim A, Hu LP, Ortiz M, Mahler-Araujo B, Vogel P, Paez-Ribes M, Fatemi A, Hannon GJ, Iyer R, Blundon JA, Lourenço FC, Kay J, Nazarian RM, Hall BA, Zakharenko SS, Winton DJ, Zhu L, Gilbertson RJNature geneticsThe NALCN channel regulates metastasis and nonmalignant cell dissemination. Nat Genet. 2022 12; 54(12):1827-1838.Nat Genet2022-09-29T00:00:002022The NALCN channel regulates metastasis and nonmalignant cell dissemination.36321551Shorthouse D, Bradley J, Critchlow SE, Bendtsen C, Hall BAMolecular systems biologyHeterogeneity of the cancer cell line metabolic landscape. Mol Syst Biol. 2022 11; 18(11):e11006.Mol Syst Biol2022-11-01T00:00:002022Heterogeneity of the cancer cell line metabolic landscape.36266286Murai K, Dentro S, Ong SH, Sood R, Fernandez-Antoran D, Herms A, Kostiou V, Abnizova I, Hall BA, Gerstung M, Jones PHNature communicationsp53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition. Nat Commun. 2022 10 20; 13(1):6206.Nat Commun2022-10-20T00:00:002022p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition.36658434Abby E, Dentro SC, Hall MWJ, Fowler JC, Ong SH, Sood R, Herms A, Piedrafita G, Abnizova I, Siebel CW, Gerstung M, Hall BA, Jones PHNature geneticsNotch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth. Nat Genet. 2023 02; 55(2):232-245.Nat Genet2023-01-19T00:00:002023Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth.http://care2prevent.comCare2Prevent: Pediatric/Adolescent HIV Programhttp://womanlab.orgWomanLab Chief Menopause Editor, Co-Investigatorhttps://neuroscience.uchicago.edu/Neuroscience Institutehttp://bmb.uchospitals.edu/Department of Biochemistry and Molecular Biologyhttp://arac.uchicago.eduArac Labhttp://sosnick.uchicago.edu/Sosnick lab websitehttps://www.uchicago-ccbandme.org/current-ccb-mentorsCCB recruitment sitehttps://www.thebeckerlaboratory.com/My Lab Sitehttps://arac.uchicago.edu/page/publicationsArac Lab Publications@demet_arac@drmonicaxmasD016159Chemicals & Drugs1783800.816799Tumor Suppressor Protein p5337468606Hall MWJ, Shorthouse D, Alcraft R, Jones PH, Hall BACommunications biologyMutations observed in somatic evolution reveal underlying gene mechanisms. Commun Biol. 2023 07 19; 6(1):753.Commun Biol2023-07-19T00:00:002023Mutations observed in somatic evolution reveal underlying gene mechanisms.Authorship 1644425D056004Activities & Behaviors682440.832982Molecular Dynamics SimulationMedicinePathologyUniversity of ChicagoMatthew J.Brady2mB7CqUMSMzMknJtY0fp/Cv/+94=Matthew J. Brady41.78927490000000-87.601250000000001226Brady, Matthew J.Associate Professor37626225King C, Fowler JC, Abnizova I, Sood RK, Hall MWJ, Szeverényi I, Tham M, Huang J, Young SM, Hall BA, Birgitte Lane E, Jones PHNature geneticsAuthor Correction: Somatic mutations in facial skin from countries of contrasting skin cancer risk. Nat Genet. 2023 Sep; 55(9):1608.Nat Genet2023-09-01T00:00:002023Author Correction: Somatic mutations in facial skin from countries of contrasting skin cancer risk.37648039Foley K, Shorthouse D, Rahrmann E, Zhuang L, Devonshire G, Gilbertson RJ, OCCAMS consortium, Fitzgerald RC, Hall BABiochimica et biophysica acta. Molecular basis of diseaseSMAD4 and KCNQ3 alterations are associated with lymph node metastases in oesophageal adenocarcinoma. Biochim Biophys Acta Mol Basis Dis. 2024 01; 1870(1):166867.Biochim Biophys Acta Mol Basis Dis2023-08-28T00:00:002023SMAD4 and KCNQ3 alterations are associated with lymph node metastases in oesophageal adenocarcinoma.37537257King C, Fowler JC, Abnizova I, Sood RK, Hall MWJ, Szeverényi I, Tham M, Huang J, Young SM, Hall BA, Birgitte Lane E, Jones PHNature geneticsSomatic mutations in facial skin from countries of contrasting skin cancer risk. Nat Genet. 2023 09; 55(9):1440-1447.Nat Genet2023-08-03T00:00:002023Somatic mutations in facial skin from countries of contrasting skin cancer risk.Authorship 16587410Authorship 16571210Authorship 166164937748809Shorthouse D, Zhuang L, Rahrmann EP, Kosmidou C, Wickham Rahrmann K, Hall M, Greenwood B, Devonshire G, Gilbertson RJ, Fitzgerald RC, Hall BALife science allianceKCNQ potassium channels modulate Wnt activity in gastro-oesophageal adenocarcinomas. Life Sci Alliance. 2023 12; 6(12).Life Sci Alliance2023-09-25T00:00:002023KCNQ potassium channels modulate Wnt activity in gastro-oesophageal adenocarcinomas.Authorship 16659311AliyaHusainAliya Husain41.78927490000000-87.601250000000001655Husain, AliyaProfessorRaviSalgiaRavi Salgia41.78927490000000-87.601250000000001937Salgia, RaviEmeritus/Emerita, ProfessorLevBecker22d/CYF1GuTQkntjbwjr93A=Lev Becker41.78927490000000-87.601250000000002508Becker, LevAssociate ProfessorRalph R.WeichselbaumxXB+DqgWEf/5hHlsaUXv9Gq0+s+oRalph R. Weichselbaum41.78927490000000-87.601250000000002521Weichselbaum, Ralph R.ProfessorYusukeNakamuraYusuke Nakamura41.78927490000000-87.60125000000000582Nakamura, YusukeEmeritus/Emerita, ProfessorSuzanneConzenSuzanne D. Conzen41.78927490000000-87.60125000000000599Conzen, SuzanneProfessorTobin R.Sosnickw3B6BLIbEO/5hHlsaUXv9Gq0+s+oTobin R. Sosnick41.78927490000000-87.60125000000000744Sosnick, Tobin R.ProfessorChristopherRhodesChristopher J. Rhodes41.78927490000000-87.60125000000000926Rhodes, ChristopherEmeritus/Emerita, Professor38185227Jamshidi Parvar S, Hall BA, Shorthouse DMethods (San Diego, Calif.)Interpreting the effect of mutations to protein binding sites from large-scale genomic screens. Methods. 2024 Feb; 222:122-132.Methods2024-01-05T00:00:002024Interpreting the effect of mutations to protein binding sites from large-scale genomic screens.Authorship 1694492Authorship 169659338272919Zerrouk N, Alcraft R, Hall BA, Augé F, Niarakis ANPJ systems biology and applicationsLarge-scale computational modelling of the M1 and M2 synovial macrophages in rheumatoid arthritis. NPJ Syst Biol Appl. 2024 Jan 26; 10(1):10.NPJ Syst Biol Appl2024-01-26T00:00:002024Large-scale computational modelling of the M1 and M2 synovial macrophages in rheumatoid arthritis.true1true1Associate ProfessorAssociate Professortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professortrue1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professortrue1Associate ProfessorAssociate Professortrue1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessorAuthorship 657584Authorship 659525Authorship 695192Authorship 697134Authorship 712051Authorship 729542Authorship 74849225644994Chuang R, Hall BA, Benque D, Cook B, Ishtiaq S, Piterman N, Taylor A, Vardi M, Koschmieder S, Gottgens B, Fisher JScientific reportsDrug target optimization in chronic myeloid leukemia using innovative computational platform. Sci Rep. 2015 Feb 03; 5:8190.Sci Rep2015-02-03T00:00:002015Drug target optimization in chronic myeloid leukemia using innovative computational platform.24016618Skor MN, Wonder EL, Kocherginsky M, Goyal A, Hall BA, Cai Y, Conzen SDClinical cancer research : an official journal of the American Association for Cancer ResearchGlucocorticoid receptor antagonism as a novel therapy for triple-negative breast cancer. Clin Cancer Res. 2013 Nov 15; 19(22):6163-72.Clin Cancer Res2013-09-09T00:00:002013Glucocorticoid receptor antagonism as a novel therapy for triple-negative breast cancer.24051986Bagnéris C, Decaen PG, Hall BA, Naylor CE, Clapham DE, Kay CW, Wallace BANature communicationsRole of the C-terminal domain in the structure and function of tetrameric sodium channels. Nat Commun. 2013; 4:2465.Nat Commun2013-01-01T00:00:002013Role of the C-terminal domain in the structure and function of tetrameric sodium channels.24397339Reddy T, Manrique S, Buyan A, Hall BA, Chetwynd A, Sansom MSBiochemistryPrimary and secondary dimer interfaces of the fibroblast growth factor receptor 3 transmembrane domain: characterization via multiscale molecular dynamics simulations. Biochemistry. 2014 Jan 21; 53(2):323-32.Biochemistry2014-01-08T00:00:002014Primary and secondary dimer interfaces of the fibroblast growth factor receptor 3 transmembrane domain: characterization via multiscale molecular dynamics simulations.24966232Hall BA, Jackson E, Hajnal A, Fisher JJournal of the Royal Society, InterfaceLogic programming to predict cell fate patterns and retrodict genotypes in organogenesis. J R Soc Interface. 2014 Sep 06; 11(98):20140245.J R Soc Interface2014-09-06T00:00:002014Logic programming to predict cell fate patterns and retrodict genotypes in organogenesis.24832224Wright DW, Hall BA, Kellam P, Coveney PVBiologyGlobal Conformational Dynamics of HIV-1 Reverse Transcriptase Bound to Non-Nucleoside Inhibitors. Biology (Basel). 2012 Jul 26; 1(2):222-44.Biology (Basel)2012-07-26T00:00:002012Global Conformational Dynamics of HIV-1 Reverse Transcriptase Bound to Non-Nucleoside Inhibitors.24043625Brickley DR, Agyeman AS, Kopp RF, Hall BA, Harbeck MC, Belova L, Volden PA, Wu W, Roe MW, Conzen SDThe Journal of biological chemistrySerum- and glucocorticoid-induced protein kinase 1 (SGK1) is regulated by store-operated Ca2+ entry and mediates cytoprotection against necrotic cell death. J Biol Chem. 2013 Nov 08; 288(45):32708-32719.J Biol Chem2013-09-16T00:00:002013Serum- and glucocorticoid-induced protein kinase 1 (SGK1) is regulated by store-operated Ca2+ entry and mediates cytoprotection against necrotic cell death.1010Authorship 80558825979343Bagnéris C, Rogala KB, Baratchian M, Zamfir V, Kunze MB, Dagless S, Pirker KF, Collins MK, Hall BA, Barrett TE, Kay CWThe Journal of biological chemistryProbing the Solution Structure of I?B Kinase (IKK) Subunit ? and Its Interaction with Kaposi Sarcoma-associated Herpes Virus Flice-interacting Protein and IKK Subunit ß by EPR Spectroscopy. J Biol Chem. 2015 Jul 03; 290(27):16539-49.J Biol Chem2015-05-14T00:00:002015Probing the Solution Structure of I?B Kinase (IKK) Subunit ? and Its Interaction with Kaposi Sarcoma-associated Herpes Virus Flice-interacting Protein and IKK Subunit ß by EPR Spectroscopy.Authorship 80788126200879Hall BA, Piterman N, Hajnal A, Fisher JBiophysical journalEmergent stem cell homeostasis in the C. elegans germline is revealed by hybrid modeling. Biophys J. 2015 Jul 21; 109(2):428-38.Biophys J2015-07-21T00:00:002015Emergent stem cell homeostasis in the C. elegans germline is revealed by hybrid modeling.Medicine-EndocrinologyMonicaChristmasMonica Christmas0.000000000000000.000000000000003234Christmas, MonicaAssociate ProfessorAuthorship 82658826386046Bagnéris C, Rogala KB, Baratchian M, Zamfir V, Kunze MB, Dagless S, Pirker KF, Collins MK, Hall BA, Barrett TE, Kay CWThe Journal of biological chemistryProbing the solution structure of I?B kinase (IKK) subunit ? and its interaction with Kaposi sarcoma-associated herpes virus Flice-interacting protein and IKK subunit ß by EPR spectroscopy. J Biol Chem. 2015 Sep 18; 290(38):23024.J Biol Chem2015-09-18T00:00:002015Probing the solution structure of I?B kinase (IKK) subunit ? and its interaction with Kaposi sarcoma-associated herpes virus Flice-interacting protein and IKK subunit ß by EPR spectroscopy.Pediatrics-Infectious DiseasesAuthorship 845141Authorship 84726126616626Hall BA, Sansom MSJournal of chemical theory and computationCoarse-Grained MD Simulations and Protein-Protein Interactions: The Cohesin-Dockerin System. J Chem Theory Comput. 2009 Sep 08; 5(9):2465-71.J Chem Theory Comput2009-09-08T00:00:002009Coarse-Grained MD Simulations and Protein-Protein Interactions: The Cohesin-Dockerin System.26580541Hall BA, Halim KB, Buyan A, Emmanouil B, Sansom MSJournal of chemical theory and computationSidekick for Membrane Simulations: Automated Ensemble Molecular Dynamics Simulations of Transmembrane Helices. J Chem Theory Comput. 2014 May 13; 10(5):2165-75.J Chem Theory Comput2014-05-13T00:00:002014Sidekick for Membrane Simulations: Automated Ensemble Molecular Dynamics Simulations of Transmembrane Helices.Authorship 93340427400148Riedel A, Shorthouse D, Haas L, Hall BA, Shields JNature immunologyTumor-induced stromal reprogramming drives lymph node transformation. Nat Immunol. 2016 09; 17(9):1118-27.Nat Immunol2016-07-11T00:00:002016Tumor-induced stromal reprogramming drives lymph node transformation.Chicago60637ILJulieChorJulie Chor0.000000000000000.000000000000002724Chor, JulieAssociate Professor1.495710.0110884318research areas0.6863810.02768385coauthor of46.64039.5014760similar to1163selected publicationsAuthorship 557233Authorship 566072Authorship 585402Authorship 570141Authorship 594802Authorship 589632Authorship 601451Authorship 594981Authorship 603802Authorship 600414Authorship 588563Authorship 591893Authorship 603791Authorship 556072Authorship 591451Authorship 601221Authorship 603222Authorship 603512Authorship 60474215572782Barrett CP, Hall BA, Noble MEActa crystallographica. Section D, Biological crystallographyDynamite: a simple way to gain insight into protein motions. Acta Crystallogr D Biol Crystallogr. 2004 Dec; 60(Pt 12 Pt 1):2280-7.Acta Crystallogr D Biol Crystallogr2004-11-26T00:00:002004Dynamite: a simple way to gain insight into protein motions.17715919Hall BA, Kaye SL, Pang A, Perera R, Biggin PCJournal of the American Chemical SocietyCharacterization of protein conformational states by normal-mode frequencies. J Am Chem Soc. 2007 Sep 19; 129(37):11394-401.J Am Chem Soc2007-08-23T00:00:002007Characterization of protein conformational states by normal-mode frequencies.15749783Haider S, Grottesi A, Hall BA, Ashcroft FM, Sansom MSBiophysical journalConformational dynamics of the ligand-binding domain of inward rectifier K channels as revealed by molecular dynamics simulations: toward an understanding of Kir channel gating. Biophys J. 2005 May; 88(5):3310-20.Biophys J2005-03-04T00:00:002005Conformational dynamics of the ligand-binding domain of inward rectifier K channels as revealed by molecular dynamics simulations: toward an understanding of Kir channel gating.17059218Haider S, Hall BA, Sansom MSBiochemistrySimulations of a protein translocation pore: SecY. Biochemistry. 2006 Oct 31; 45(43):13018-24.Biochemistry2006-10-31T00:00:002006Simulations of a protein translocation pore: SecY.23030363Vostrikov VV, Hall BA, Sansom MS, Koeppe REThe journal of physical chemistry. BAccommodation of a central arginine in a transmembrane peptide by changing the placement of anchor residues. J Phys Chem B. 2012 Nov 01; 116(43):12980-90.J Phys Chem B2012-10-17T00:00:002012Accommodation of a central arginine in a transmembrane peptide by changing the placement of anchor residues.23028283Hall BA, Armitage JP, Sansom MSPLoS computational biologyMechanism of bacterial signal transduction revealed by molecular dynamics of Tsr dimers and trimers of dimers in lipid vesicles. PLoS Comput Biol. 2012; 8(9):e1002685.PLoS Comput Biol2012-09-20T00:00:002012Mechanism of bacterial signal transduction revealed by molecular dynamics of Tsr dimers and trimers of dimers in lipid vesicles.21504730Hall BA, Chetwynd AP, Sansom MSBiophysical journalExploring peptide-membrane interactions with coarse-grained MD simulations. Biophys J. 2011 Apr 20; 100(8):1940-8.Biophys J2011-04-20T00:00:002011Exploring peptide-membrane interactions with coarse-grained MD simulations.22866962Hall BA, Wright DW, Jha S, Coveney PVBiochemistryQuantized water access to the HIV-1 protease active site as a proposed mechanism for cooperative mutations in drug affinity. Biochemistry. 2012 Aug 21; 51(33):6487-9.Biochemistry2012-08-08T00:00:002012Quantized water access to the HIV-1 protease active site as a proposed mechanism for cooperative mutations in drug affinity.22000516Kalli AC, Hall BA, Campbell ID, Sansom MSStructure (London, England : 1993)A helix heterodimer in a lipid bilayer: prediction of the structure of an integrin transmembrane domain via multiscale simulations. Structure. 2011 Oct 12; 19(10):1477-84.Structure2011-10-12T00:00:002011A helix heterodimer in a lipid bilayer: prediction of the structure of an integrin transmembrane domain via multiscale simulations.21566123Watson AA, Lebedev AA, Hall BA, Fenton-May AE, Vagin AA, Dejnirattisai W, Felce J, Mongkolsapaya J, Palma AS, Liu Y, Feizi T, Screaton GR, Murshudov GN, O'Callaghan CAThe Journal of biological chemistryStructural flexibility of the macrophage dengue virus receptor CLEC5A: implications for ligand binding and signaling. J Biol Chem. 2011 Jul 08; 286(27):24208-18.J Biol Chem2011-05-12T00:00:002011Structural flexibility of the macrophage dengue virus receptor CLEC5A: implications for ligand binding and signaling.20959094Chetwynd A, Wee CL, Hall BA, Sansom MSBiophysical journalThe energetics of transmembrane helix insertion into a lipid bilayer. Biophys J. 2010 Oct 20; 99(8):2534-40.Biophys J2010-10-20T00:00:002010The energetics of transmembrane helix insertion into a lipid bilayer.21169341Vohra S, Hall BA, Holdbrook DA, Khalid S, Biggin PCDatabase : the journal of biological databases and curationBookshelf: a simple curation system for the storage of biomolecular simulation data. Database (Oxford). 2010; 2010:baq033.Database (Oxford)2010-12-17T00:00:002010Bookshelf: a simple curation system for the storage of biomolecular simulation data.23009845Lindau M, Hall BA, Chetwynd A, Beckstein O, Sansom MSBiophysical journalCoarse-grain simulations reveal movement of the synaptobrevin C-terminus in response to piconewton forces. Biophys J. 2012 Sep 05; 103(5):959-69.Biophys J2012-09-05T00:00:002012Coarse-grain simulations reveal movement of the synaptobrevin C-terminus in response to piconewton forces.23094791Crowet JM, Parton DL, Hall BA, Steinhauer S, Brasseur R, Lins L, Sansom MSThe journal of physical chemistry. BMulti-scale simulation of the simian immunodeficiency virus fusion peptide. J Phys Chem B. 2012 Nov 26; 116(46):13713-21.J Phys Chem B2012-11-09T00:00:002012Multi-scale simulation of the simian immunodeficiency virus fusion peptide.22028633Hall BA, Armitage JP, Sansom MSPLoS computational biologyTransmembrane helix dynamics of bacterial chemoreceptors supports a piston model of signalling. PLoS Comput Biol. 2011 Oct; 7(10):e1002204.PLoS Comput Biol2011-10-20T00:00:002011Transmembrane helix dynamics of bacterial chemoreceptors supports a piston model of signalling.22995497Doux JP, Hall BA, Killian JABiophysical journalHow lipid headgroups sense the membrane environment: an application of ¹4N NMR. Biophys J. 2012 Sep 19; 103(6):1245-53.Biophys J2012-09-19T00:00:002012How lipid headgroups sense the membrane environment: an application of ¹4N NMR.20373735Vostrikov VV, Hall BA, Greathouse DV, Koeppe RE, Sansom MSJournal of the American Chemical SocietyChanges in transmembrane helix alignment by arginine residues revealed by solid-state NMR experiments and coarse-grained MD simulations. J Am Chem Soc. 2010 Apr 28; 132(16):5803-11.J Am Chem Soc2010-04-28T00:00:002010Changes in transmembrane helix alignment by arginine residues revealed by solid-state NMR experiments and coarse-grained MD simulations.