AinhoaArinaAinhoa Arina0.000000000000000.000000000000002797Arina, AinhoaResearch Associate Professorplugins:TwitterTwitterprns:coAuthorOfcoauthor ofprns:emailEncryptedemail addressFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:pluginSearchableDataProfilesRNS Plugin Searchable Dataprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 101266125050213Arina AOncoimmunologyRethinking the role of myeloid-derived suppressor cells in adoptive T-cell therapy for cancer. Oncoimmunology. 2014; 3:e28464.Oncoimmunology2014-04-15T00:00:002014Rethinking the role of myeloid-derived suppressor cells in adoptive T-cell therapy for cancer.Authorship 104653128445461Kammertoens T, Friese C, Arina A, Idel C, Briesemeister D, Rothe M, Ivanov A, Szymborska A, Patone G, Kunz S, Sommermeyer D, Engels B, Leisegang M, Textor A, Fehling HJ, Fruttiger M, Lohoff M, Herrmann A, Yu H, Weichselbaum R, Uckert W, Hübner N, Gerhardt H, Beule D, Schreiber H, Blankenstein TNatureTumour ischaemia by interferon-? resembles physiological blood vessel regression. Nature. 2017 05 04; 545(7652):98-102.Nature2017-04-26T00:00:002017Tumour ischaemia by interferon-? resembles physiological blood vessel regression.JeffreyHubbell3Wp8CaMQFeD5hHlsaUXv9Gq0+s+oJeffrey Hubbell41.7886000000000087.598699999999993473Hubbell, JeffreyBarry L. MacLean ProfessorRadiation and Cellular OncologyAuthorship 11677811Authorship 1212358Authorship 121836830482772Ranoa DRE, Widau RC, Mallon S, Parekh AD, Nicolae CM, Huang X, Bolt MJ, Arina A, Parry R, Kron SJ, Moldovan GL, Khodarev NN, Weichselbaum RRCancer researchSTING Promotes Homeostasis via Regulation of Cell Proliferation and Chromosomal Stability. Cancer Res. 2019 04 01; 79(7):1465-1479.Cancer Res2018-11-27T00:00:002018STING Promotes Homeostasis via Regulation of Cell Proliferation and Chromosomal Stability.29437535Luke JJ, Lemons JM, Karrison TG, Pitroda SP, Melotek JM, Zha Y, Al-Hallaq HA, Arina A, Khodarev NN, Janisch L, Chang P, Patel JD, Fleming GF, Moroney J, Sharma MR, White JR, Ratain MJ, Gajewski TF, Weichselbaum RR, Chmura SJJournal of clinical oncology : official journal of the American Society of Clinical OncologySafety and Clinical Activity of Pembrolizumab and Multisite Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors. J Clin Oncol. 2018 06 01; 36(16):1611-1618.J Clin Oncol2018-02-13T00:00:002018Safety and Clinical Activity of Pembrolizumab and Multisite Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors.30170810Hou Y, Liang H, Rao E, Zheng W, Huang X, Deng L, Zhang Y, Yu X, Xu M, Mauceri H, Arina A, Weichselbaum RR, Fu YXImmunityNon-canonical NF-?B Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy. Immunity. 2018 09 18; 49(3):490-503.e4.Immunity2018-08-28T00:00:002018Non-canonical NF-?B Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy.D007167Procedures1836270.665954ImmunotherapyAuthorship 132696131477729Arina A, Beckett M, Fernandez C, Zheng W, Pitroda S, Chmura SJ, Luke JJ, Forde M, Hou Y, Burnette B, Mauceri H, Lowy I, Sims T, Khodarev N, Fu YX, Weichselbaum RRNature communicationsTumor-reprogrammed resident T cells resist radiation to control tumors. Nat Commun. 2019 09 02; 10(1):3959.Nat Commun2019-09-02T00:00:002019Tumor-reprogrammed resident T cells resist radiation to control tumors.Pritzker Institute for Molecular EngineeringAuthorship 135842132047000Arina A, Gutiontov SI, Weichselbaum RRClinical cancer research : an official journal of the American Association for Cancer ResearchRadiotherapy and Immunotherapy for Cancer: From "Systemic" to "Multisite". Clin Cancer Res. 2020 06 15; 26(12):2777-2782.Clin Cancer Res2020-02-11T00:00:002020Radiotherapy and Immunotherapy for Cancer: From "Systemic" to "Multisite".D011878Procedures1213260.839686RadiotherapyAuthorship 140168432819613Gutiontov SI, Pitroda SP, Chmura SJ, Arina A, Weichselbaum RRInternational journal of radiation oncology, biology, physicsCytoreduction and the Optimization Of Immune Checkpoint Inhibition with Radiation Therapy. Int J Radiat Oncol Biol Phys. 2020 09 01; 108(1):17-26.Int J Radiat Oncol Biol Phys2020-09-01T00:00:002020Cytoreduction and the Optimization Of Immune Checkpoint Inhibition with Radiation Therapy.MichaelGluthMichael Gluth0.000000000000000.000000000000002862Gluth, MichaelProfessorDaniel W.Golden02VmB6UQF8zMknJtY0fp/Cv/+94=Daniel W. Golden0.000000000000000.000000000000002892Golden, Daniel W.Associate ProfessorSurgery-Otolaryngology-Head and NeckAuthorship 1446281633627484Hou Y, Liang HL, Yu X, Liu Z, Cao X, Rao E, Huang X, Wang L, Li L, Bugno J, Fu Y, Chmura SJ, Wu W, Luo SZ, Zheng W, Arina A, Jutzy J, McCall AR, Vokes EE, Pitroda SP, Fu YX, Weichselbaum RRScience translational medicineRadiotherapy and immunotherapy converge on elimination of tumor-promoting erythroid progenitor cells through adaptive immunity. Sci Transl Med. 2021 02 24; 13(582).Sci Transl Med2021-02-24T00:00:002021Radiotherapy and immunotherapy converge on elimination of tumor-promoting erythroid progenitor cells through adaptive immunity.Authorship 144852833707466Voce DJ, Bernal GM, Cahill KE, Wu L, Mansour N, Crawley CD, Campbell PS, Arina A, Weichselbaum RR, Yamini BScientific reportsCDK1 is up-regulated by temozolomide in an NF-?B dependent manner in glioblastoma. Sci Rep. 2021 03 11; 11(1):5665.Sci Rep2021-03-11T00:00:002021CDK1 is up-regulated by temozolomide in an NF-?B dependent manner in glioblastoma.D016246Anatomy641230.898015Lymphocytes, Tumor-InfiltratingD009374Disorders1092690.859676Neoplasms, Experimental22374983Liu RB, Engels B, Arina A, Schreiber K, Hyjek E, Schietinger A, Binder DC, Butz E, Krausz T, Rowley DA, Jabri B, Schreiber HCancer researchDensely granulated murine NK cells eradicate large solid tumors. Cancer Res. 2012 Apr 15; 72(8):1964-74.Cancer Res2012-02-28T00:00:002012Densely granulated murine NK cells eradicate large solid tumors.21714479Wu TH, Schreiber K, Arina A, Khodarev NN, Efimova EV, Rowley DA, Weichselbaum RR, Schreiber HCancer immunityProgression of cancer from indolent to aggressive despite antigen retention and increased expression of interferon-gamma inducible genes. Cancer Immun. 2011 Jun 30; 11:2.Cancer Immun2011-06-30T00:00:002011Progression of cancer from indolent to aggressive despite antigen retention and increased expression of interferon-gamma inducible genes.22415314Schreiber K, Arina A, Engels B, Spiotto MT, Sidney J, Sette A, Karrison TG, Weichselbaum RR, Rowley DA, Schreiber HClinical cancer research : an official journal of the American Association for Cancer ResearchSpleen cells from young but not old immunized mice eradicate large established cancers. Clin Cancer Res. 2012 May 01; 18(9):2526-33.Clin Cancer Res2012-03-13T00:00:002012Spleen cells from young but not old immunized mice eradicate large established cancers.Authorship 150668534709030Guo N, Ni K, Luo T, Lan G, Arina A, Xu Z, Mao J, Weichselbaum RR, Spiotto M, Lin WACS nanoReprogramming of Neutrophils as Non-canonical Antigen Presenting Cells by Radiotherapy-Radiodynamic Therapy to Facilitate Immune-Mediated Tumor Regression. ACS Nano. 2021 11 23; 15(11):17515-17527.ACS Nano2021-10-28T00:00:002021Reprogramming of Neutrophils as Non-canonical Antigen Presenting Cells by Radiotherapy-Radiodynamic Therapy to Facilitate Immune-Mediated Tumor Regression.Public Health Scienceshttps://voices.uchicago.edu/radioimmunotherapycenter/RadioImmunotherapyhttp://roecsg.uchicago.edu/Radiation Oncology Education Collaborative Study Group (ROECSG)d_golden@docace911@SeanPitrodaD009369Disorders55628890.33847NeoplasmsMedicinePathologyUniversity of ChicagoHansSchreiberHans Schreiber41.78927490000000-87.601250000000001921Schreiber, HansProfessorTheodoreKarrisonTheodore Karrison41.78927490000000-87.601250000000002356Karrison, TheodoreResearch ProfessorRalph R.WeichselbaumxXB+DqgWEf/5hHlsaUXv9Gq0+s+oRalph R. Weichselbaum41.78927490000000-87.601250000000002521Weichselbaum, Ralph R.ProfessorThomas F.GajewskiThomas F. Gajewski41.78927490000000-87.60125000000000355Gajewski, Thomas F.ProfessorStevenChmuraxGhqA6x1C+35hHlsaUXv9Gq0+s+oSteven Chmura41.78927490000000-87.60125000000000417Chmura, StevenProfessorYusukeNakamuraYusuke Nakamura41.78927490000000-87.60125000000000582Nakamura, YusukeEmeritus/Emerita, ProfessorAuthorship 1687971438099498Wang L, Si W, Yu X, Piffko A, Dou X, Ding X, Bugno J, Yang K, Wen C, Zhang L, Chen D, Huang X, Wang J, Arina A, Pitroda S, Chmura SJ, He C, Liang HL, Weichselbaum RThe Journal of clinical investigationEpitranscriptional regulation of TGF-ß pseudoreceptor BAMBI by m6A/YTHDF2 drives extrinsic radioresistance. J Clin Invest. 2023 Dec 15; 133(24).J Clin Invest2023-12-15T00:00:002023Epitranscriptional regulation of TGF-ß pseudoreceptor BAMBI by m6A/YTHDF2 drives extrinsic radioresistance.true1Emeritus/Emerita, ProfessorEmeritus/Emerita, Professortrue1Clinical AssociateClinical Associatetrue1ProfessorProfessortrue1ProfessorProfessortrue1Barry L. MacLean ProfessorBarry L. MacLean Professortrue1Research ProfessorResearch Professortrue1Associate ProfessorAssociate Professortrue1Associate ProfessorAssociate Professortrue1Research Associate ProfessorResearch Associate Professortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1ProfessorProfessorAuthorship 671286Authorship 722043Authorship 73742125517616Deng L, Liang H, Xu M, Yang X, Burnette B, Arina A, Li XD, Mauceri H, Beckett M, Darga T, Huang X, Gajewski TF, Chen ZJ, Fu YX, Weichselbaum RRImmunitySTING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors. Immunity. 2014 Nov 20; 41(5):843-52.Immunity2014-11-06T00:00:002014STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors.24367029Arina A, Schreiber K, Binder DC, Karrison TG, Liu RB, Schreiber HJournal of immunology (Baltimore, Md. : 1950)Adoptively transferred immune T cells eradicate established tumors despite cancer-induced immune suppression. J Immunol. 2014 Feb 01; 192(3):1286-93.J Immunol2013-12-23T00:00:002013Adoptively transferred immune T cells eradicate established tumors despite cancer-induced immune suppression.24455752Binder DC, Engels B, Arina A, Yu P, Slauch JM, Fu YX, Karrison T, Burnette B, Idel C, Zhao M, Hoffman RM, Munn DH, Rowley DA, Schreiber HCancer immunology researchAntigen-specific bacterial vaccine combined with anti-PD-L1 rescues dysfunctional endogenous T cells to reject long-established cancer. Cancer Immunol Res. 2013 Aug; 1(2):123-33.Cancer Immunol Res2013-08-01T00:00:002013Antigen-specific bacterial vaccine combined with anti-PD-L1 rescues dysfunctional endogenous T cells to reject long-established cancer.1010Authorship 80003125728992Arina A, Bronte VCurrent opinion in immunologyMyeloid-derived suppressor cell impact on endogenous and adoptively transferred T cells. Curr Opin Immunol. 2015 Apr; 33:120-5.Curr Opin Immunol2015-02-27T00:00:002015Myeloid-derived suppressor cell impact on endogenous and adoptively transferred T cells.Authorship 89729126872631Arina A, Corrales L, Bronte VSeminars in immunologyEnhancing T cell therapy by overcoming the immunosuppressive tumor microenvironment. Semin Immunol. 2016 02; 28(1):54-63.Semin Immunol2016-02-10T00:00:002016Enhancing T cell therapy by overcoming the immunosuppressive tumor microenvironment.Authorship 90315626667491Leisegang M, Engels B, Schreiber K, Yew PY, Kiyotani K, Idel C, Arina A, Duraiswamy J, Weichselbaum RR, Uckert W, Nakamura Y, Schreiber HClinical cancer research : an official journal of the American Association for Cancer ResearchEradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation. Clin Cancer Res. 2016 06 01; 22(11):2734-43.Clin Cancer Res2015-12-14T00:00:002015Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation.Authorship 91360127317748Arina A, Idel C, Hyjek EM, Alegre ML, Wang Y, Bindokas VP, Weichselbaum RR, Schreiber HProceedings of the National Academy of Sciences of the United States of AmericaTumor-associated fibroblasts predominantly come from local and not circulating precursors. Proc Natl Acad Sci U S A. 2016 07 05; 113(27):7551-6.Proc Natl Acad Sci U S A2016-06-17T00:00:002016Tumor-associated fibroblasts predominantly come from local and not circulating precursors.SeanPitrodaSean Pitroda0.000000000000000.000000000000003299Pitroda, SeanAssociate ProfessorAuthorship 92568227471609Binder DC, Arina A, Wen F, Tu T, Zhao M, Hoffman RM, Wainwright DA, Schreiber HOncoimmunologyTumor relapse prevented by combining adoptive T cell therapy with Salmonella typhimurium. Oncoimmunology. 2016 Jun; 5(6):e1130207.Oncoimmunology2016-02-18T00:00:002016Tumor relapse prevented by combining adoptive T cell therapy with Salmonella typhimurium.ChristinaSonChristina Son0.000000000000000.000000000000003362Son, ChristinaAssociate ProfessorChicago60637ILJosephAsburyJoseph Asbury0.000000000000000.000000000000002793Asbury, JosephClinical Associate2.295140.0092931290research areas3.298750.027055427coauthor of91.39238.2275860similar to1152selected publicationsAuthorship 563245Authorship 543673Authorship 577201Authorship 581622Authorship 556981Authorship 546326Authorship 560492Authorship 548254Authorship 542675Authorship 550612Authorship 550643Authorship 563415Authorship 551441Authorship 556215Authorship 568698Authorship 5689111Authorship 562363Authorship 571555Authorship 5730012Authorship 570854Authorship 553141Authorship 557494Authorship 557923Authorship 592853Authorship 597613Authorship 597832Authorship 563291Authorship 582913Authorship 61074611916305Tirapu I, Mazzolini G, Rodriguez-Calvillo M, Arina A, Palencia B, Gabari I, Melero IArchivum immunologiae et therapiae experimentalisEffective tumor immunotherapy: start the engine, release the brakes, step on the gas pedal,...and get ready to face autoimmunity. Arch Immunol Ther Exp (Warsz). 2002; 50(1):13-8.Arch Immunol Ther Exp (Warsz)2002-01-01T00:00:002002Effective tumor immunotherapy: start the engine, release the brakes, step on the gas pedal,...and get ready to face autoimmunity.12482496Arina A, Tirapu I, Alfaro C, Rodríguez-Calvillo M, Mazzolini G, Inogés S, López A, Feijoo E, Bendandi M, Melero IExperimental hematologyClinical implications of antigen transfer mechanisms from malignant to dendritic cells. exploiting cross-priming. Exp Hematol. 2002 Dec; 30(12):1355-64.Exp Hematol2002-12-01T00:00:002002Clinical implications of antigen transfer mechanisms from malignant to dendritic cells. exploiting cross-priming.12808437Mazzolini G, Narvaiza I, Martinez-Cruz LA, Arina A, Barajas M, Galofré JC, Qian C, Mato JM, Prieto J, Melero IGene therapyPancreatic cancer escape variants that evade immunogene therapy through loss of sensitivity to IFNgamma-induced apoptosis. Gene Ther. 2003 Jul; 10(13):1067-78.Gene Ther2003-07-01T00:00:002003Pancreatic cancer escape variants that evade immunogene therapy through loss of sensitivity to IFNgamma-induced apoptosis.14512536Sarobe P, Lasarte JJ, Zabaleta A, Arribillaga L, Arina A, Melero I, Borrás-Cuesta F, Prieto JJournal of virologyHepatitis C virus structural proteins impair dendritic cell maturation and inhibit in vivo induction of cellular immune responses. J Virol. 2003 Oct; 77(20):10862-71.J Virol2003-10-01T00:00:002003Hepatitis C virus structural proteins impair dendritic cell maturation and inhibit in vivo induction of cellular immune responses.15709906Huarte E, Tirapu I, Arina A, Vera M, Alfaro C, Murillo O, Palencia B, Busto V, Marín V, Mazzolini G, Melero IExpert opinion on biological therapyIntratumoural administration of dendritic cells: hostile environment and help by gene therapy. Expert Opin Biol Ther. 2005 Jan; 5(1):7-22.Expert Opin Biol Ther2005-01-01T00:00:002005Intratumoural administration of dendritic cells: hostile environment and help by gene therapy.15800914Feijoó E, Alfaro C, Mazzolini G, Serra P, Peñuelas I, Arina A, Huarte E, Tirapu I, Palencia B, Murillo O, Ruiz J, Sangro B, Richter JA, Prieto J, Melero IInternational journal of cancerDendritic cells delivered inside human carcinomas are sequestered by interleukin-8. Int J Cancer. 2005 Aug 20; 116(2):275-81.Int J Cancer2005-08-20T00:00:002005Dendritic cells delivered inside human carcinomas are sequestered by interleukin-8.16670731Alfaro C, Murillo O, Tirapu I, Azpilicueta A, Huarte E, Arina A, Arribillaga L, Pérez-Gracia JL, Bendandi M, Prieto J, Lasarte JJ, Melero IAnales del sistema sanitario de Navarra[The immunotherapy potential of agonistic anti-CD137 (4-1BB) monoclonal antibodies for malignancies and chronic viral diseases]. An Sist Sanit Navar. 2006 Jan-Apr; 29(1):77-96.An Sist Sanit Navar2006-01-01T00:00:002006[The immunotherapy potential of agonistic anti-CD137 (4-1BB) monoclonal antibodies for malignancies and chronic viral diseases].17990348Mazzolini G, Murillo O, Atorrasagasti C, Dubrot J, Tirapu I, Rizzo M, Arina A, Alfaro C, Azpilicueta A, Berasain C, Perez-Gracia JL, Gonzalez A, Melero IWorld journal of gastroenterologyImmunotherapy and immunoescape in colorectal cancer. World J Gastroenterol. 2007 Nov 28; 13(44):5822-31.World J Gastroenterol2007-11-28T00:00:002007Immunotherapy and immunoescape in colorectal cancer.11763169Rivas AL, Quimby FW, Coksaygan O, Alba A, Arina A, Arrobas MJ, González RN, Mohammed HO, Lein DHAmerican journal of veterinary researchExpression of CD3 and CD11b antigens on blood and mammary gland leukocytes and bacterial survival in milk of cows with experimentally induced Staphylococcus aureus mastitis. Am J Vet Res. 2001 Dec; 62(12):1840-51.Am J Vet Res2001-12-01T00:00:002001Expression of CD3 and CD11b antigens on blood and mammary gland leukocytes and bacterial survival in milk of cows with experimentally induced Staphylococcus aureus mastitis.16234580Melero I, Arina A, Chen LImmunologic researchThe many sounds of T lymphocyte silence. Immunol Res. 2005; 33(2):135-47.Immunol Res2005-01-01T00:00:002005The many sounds of T lymphocyte silence.14506140Melero I, Gabari I, Tirapu I, Arina A, Mazzolini G, Baixeras E, Feijoo E, Alfaro C, Qian C, Prieto JClinical cancer research : an official journal of the American Association for Cancer ResearchAnti-ICAM-2 monoclonal antibody synergizes with intratumor gene transfer of interleukin-12 inhibiting activation-induced T-cell death. Clin Cancer Res. 2003 Sep 01; 9(10 Pt 1):3546-54.Clin Cancer Res2003-09-01T00:00:002003Anti-ICAM-2 monoclonal antibody synergizes with intratumor gene transfer of interleukin-12 inhibiting activation-induced T-cell death.15054868Tirapu I, Arina A, Mazzolini G, Duarte M, Alfaro C, Feijoo E, Qian C, Chen L, Prieto J, Melero IInternational journal of cancerImproving efficacy of interleukin-12-transfected dendritic cells injected into murine colon cancer with anti-CD137 monoclonal antibodies and alloantigens. Int J Cancer. 2004 May 20; 110(1):51-60.Int J Cancer2004-05-20T00:00:002004Improving efficacy of interleukin-12-transfected dendritic cells injected into murine colon cancer with anti-CD137 monoclonal antibodies and alloantigens.16638842Melero I, Arina A, Murillo O, Dubrot J, Alfaro C, Pérez-Gracia JL, Bendandi M, Hervás-Stubbs SClinical cancer research : an official journal of the American Association for Cancer ResearchImmunogenic cell death and cross-priming are reaching the clinical immunotherapy arena. Clin Cancer Res. 2006 Apr 15; 12(8):2385-9.Clin Cancer Res2006-04-15T00:00:002006Immunogenic cell death and cross-priming are reaching the clinical immunotherapy arena.17897835Rodriguez M, Alvarez-Erviti L, Blesa FJ, Rodríguez-Oroz MC, Arina A, Melero I, Ramos LI, Obeso JANeurobiology of diseaseBone-marrow-derived cell differentiation into microglia: a study in a progressive mouse model of Parkinson's disease. Neurobiol Dis. 2007 Dec; 28(3):316-25.Neurobiol Dis2007-08-07T00:00:002007Bone-marrow-derived cell differentiation into microglia: a study in a progressive mouse model of Parkinson's disease.19865177Murillo O, Ochoa MC, Arina A, Gabari I, Dubrot J, Hervas-Stubbs S, Melero IGene therapyProliferating NK cells in response to IL-15 do not upregulate surface B220 in vivo. Gene Ther. 2010 May; 17(5):687-9.Gene Ther2009-10-29T00:00:002009Proliferating NK cells in response to IL-15 do not upregulate surface B220 in vivo.18273053Arina A, Murillo O, Dubrot J, Azpilikueta A, Gabari I, Perez-Gracia JL, Alfaro C, Berasain C, Prieto J, Ferrini S, Hervas-Stubbs S, Melero IGene therapyInterleukin-15 liver gene transfer increases the number and function of IKDCs and NK cells. Gene Ther. 2008 Apr; 15(7):473-83.Gene Ther2008-02-14T00:00:002008Interleukin-15 liver gene transfer increases the number and function of IKDCs and NK cells.14654524Murillo O, Arina A, Tirapu I, Alfaro C, Mazzolini G, Palencia B, López-Diaz De Cerio A, Prieto J, Bendandi M, Melero IClinical cancer research : an official journal of the American Association for Cancer ResearchPotentiation of therapeutic immune responses against malignancies with monoclonal antibodies. Clin Cancer Res. 2003 Nov 15; 9(15):5454-64.Clin Cancer Res2003-11-15T00:00:002003Potentiation of therapeutic immune responses against malignancies with monoclonal antibodies.15855007Arribillaga L, Sarobe P, Arina A, Gorraiz M, Borrás-Cuesta F, Ruiz J, Prieto J, Chen L, Melero I, Lasarte JJVaccineEnhancement of CD4 and CD8 immunity by anti-CD137 (4-1BB) monoclonal antibodies during hepatitis C vaccination with recombinant adenovirus. Vaccine. 2005 May 20; 23(27):3493-9.Vaccine2005-05-20T00:00:002005Enhancement of CD4 and CD8 immunity by anti-CD137 (4-1BB) monoclonal antibodies during hepatitis C vaccination with recombinant adenovirus.18980984Murillo O, Arina A, Hervas-Stubbs S, Gupta A, McCluskey B, Dubrot J, Palazón A, Azpilikueta A, Ochoa MC, Alfaro C, Solano S, Pérez-Gracia JL, Oyajobi BO, Melero IClinical cancer research : an official journal of the American Association for Cancer ResearchTherapeutic antitumor efficacy of anti-CD137 agonistic monoclonal antibody in mouse models of myeloma. Clin Cancer Res. 2008 Nov 01; 14(21):6895-906.Clin Cancer Res2008-11-01T00:00:002008Therapeutic antitumor efficacy of anti-CD137 agonistic monoclonal antibody in mouse models of myeloma.23285013Ochoa MC, Fioravanti J, Duitman EH, Medina-Echeverz J, Palazon A, Arina A, Dubrot J, Alfaro C, Morales-Kastresana A, Murillo O, Hervas-Stubbs S, Prieto J, Berraondo P, Melero IPloS oneLiver gene transfer of interkeukin-15 constructs that become part of circulating high density lipoproteins for immunotherapy. PLoS One. 2012; 7(12):e52370.PLoS One2012-12-21T00:00:002012Liver gene transfer of interkeukin-15 constructs that become part of circulating high density lipoproteins for immunotherapy.16627004Huarte E, Larrea E, Hernández-Alcoceba R, Alfaro C, Murillo O, Arina A, Tirapu I, Azpilicueta A, Hervás-Stubbs S, Bortolanza S, Pérez-Gracia JL, Civeira MP, Prieto J, Riezu-Boj JI, Melero IMolecular therapy : the journal of the American Society of Gene TherapyRecombinant adenoviral vectors turn on the type I interferon system without inhibition of transgene expression and viral replication. Mol Ther. 2006 Jul; 14(1):129-38.Mol Ther2006-04-19T00:00:002006Recombinant adenoviral vectors turn on the type I interferon system without inhibition of transgene expression and viral replication.16489051Tirapu I, Huarte E, Guiducci C, Arina A, Zaratiegui M, Murillo O, Gonzalez A, Berasain C, Berraondo P, Fortes P, Prieto J, Colombo MP, Chen L, Melero ICancer researchLow surface expression of B7-1 (CD80) is an immunoescape mechanism of colon carcinoma. Cancer Res. 2006 Feb 15; 66(4):2442-50.Cancer Res2006-02-15T00:00:002006Low surface expression of B7-1 (CD80) is an immunoescape mechanism of colon carcinoma.15598979Mazzolini G, Alfaro C, Sangro B, Feijoó E, Ruiz J, Benito A, Tirapu I, Arina A, Sola J, Herraiz M, Lucena F, Olagüe C, Subtil J, Quiroga J, Herrero I, Sádaba B, Bendandi M, Qian C, Prieto J, Melero IJournal of clinical oncology : official journal of the American Society of Clinical OncologyIntratumoral injection of dendritic cells engineered to secrete interleukin-12 by recombinant adenovirus in patients with metastatic gastrointestinal carcinomas. J Clin Oncol. 2005 Feb 10; 23(5):999-1010.J Clin Oncol2004-12-14T00:00:002004Intratumoral injection of dendritic cells engineered to secrete interleukin-12 by recombinant adenovirus in patients with metastatic gastrointestinal carcinomas.17477799Arina A, Murillo O, Dubrot J, Azpilikueta A, Alfaro C, Pérez-Gracia JL, Bendandi M, Palencia B, Hervás-Stubbs S, Melero IExpert opinion on biological therapyCellular liaisons of natural killer lymphocytes in immunology and immunotherapy of cancer. Expert Opin Biol Ther. 2007 May; 7(5):599-615.Expert Opin Biol Ther2007-05-01T00:00:002007Cellular liaisons of natural killer lymphocytes in immunology and immunotherapy of cancer.17520674Arina A, Murillo O, Hervás-Stubbs S, Azpilikueta A, Dubrot J, Tirapu I, Huarte E, Alfaro C, Pérez-Gracia JL, González-Aseguinolaza G, Sarobe P, Lasarte JJ, Jamieson A, Prieto J, Raulet DH, Melero IInternational journal of cancerThe combined actions of NK and T lymphocytes are necessary to reject an EGFP+ mesenchymal tumor through mechanisms dependent on NKG2D and IFN gamma. 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