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research areas: Nucleosomes
research areas: DNA, Fungal
research areas: Lactase
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Reduced signal for polygenic adaptation of height in UK Biobank.
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author list: Berg JJ, Harpak A, Sinnott-Armstrong N, Joergensen AM, Mostafavi H, Field Y, Boyle EA, Zhang X, Racimo F, Pritchard JK, Coop G
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Rare penetrant mutations confer severe risk of common diseases.
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The landscape of tolerated genetic variation in humans and primates.
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published in: bioRxiv : the preprint server for biology
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Rare penetrant mutations confer severe risk of common diseases.
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The landscape of tolerated genetic variation in humans and primates.
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author list: Gao H, Hamp T, Ede J, Schraiber JG, McRae J, Singer-Berk M, Yang Y, Dietrich ASD, Fiziev PP, Kuderna LFK, Sundaram L, Wu Y, Adhikari A, Field Y, Chen C, Batzoglou S, Aguet F, Lemire G, Reimers R, Balick D, Janiak MC, Kuhlwilm M, Orkin JD, Manu S, Valenzuela A, Bergman J, Rousselle M, Silva FE, Agueda L, Blanc J, Gut M, de Vries D, Goodhead I, Harris RA, Raveendran M, Jensen A, Chuma IS, Horvath JE, Hvilsom C, Juan D, Frandsen P, de Melo FR, Bertuol F, Byrne H, Sampaio I, Farias I, do Amaral JV, Messias M, da Silva MNF, Trivedi M, Rossi R, Hrbek T, Andriaholinirina N, Rabarivola CJ, Zaramody A, Jolly CJ, Phillips-Conroy J, Wilkerson G, Abee C, Simmons JH, Fernandez-Duque E, Kanthaswamy S, Shiferaw F, Wu D, Zhou L, Shao Y, Zhang G, Keyyu JD, Knauf S, Le MD, Lizano E, Merker S, Navarro A, Bataillon T, Nadler T, Khor CC, Lee J, Tan P, Lim WK, Kitchener AC, Zinner D, Gut I, Melin A, Guschanski K, Schierup MH, Beck RMD, Umapathy G, Roos C, Boubli JP, Lek M, Sunyaev S, O'Donnell-Luria A, Rehm HL, Xu J, Rogers J, Marques-Bonet T, Farh KK
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Lactase
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linked information resource: Distinct modes of regulation by chromatin encoded through nucleosome positioning signals.

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linked information resource: The DNA-encoded nucleosome organization of a eukaryotic genome.

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linked information resource: Gene expression divergence in yeast is coupled to evolution of DNA-encoded nucleosome organization.

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linked information resource: Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells.

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linked information resource: A genomic code for nucleosome positioning.

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linked information resource: Systematic functional characterization of cis-regulatory motifs in human core promoters.

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linked information resource: How transcription factors identify regulatory sites in genomic sequence.

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linked information resource: p53 binds preferentially to genomic regions with high DNA-encoded nucleosome occupancy.

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linked information resource: Two DNA-encoded strategies for increasing expression with opposing effects on promoter dynamics and transcriptional noise.

Systematic functional characterization of cis-regulatory motifs in human core promoters.
PubMed Identifier: 18256240
author list: Sinha S, Adler AS, Field Y, Chang HY, Segal E
published in: Genome research
information resource reference: Systematic functional characterization of cis-regulatory motifs in human core promoters. Genome Res. 2008 Mar; 18(3):477-88.
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A genomic code for nucleosome positioning.
PubMed Identifier: 16862119
author list: Segal E, Fondufe-Mittendorf Y, Chen L, Thåström A, Field Y, Moore IK, Wang JP, Widom J
published in: Nature
information resource reference: A genomic code for nucleosome positioning. Nature. 2006 Aug 17; 442(7104):772-8.
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How transcription factors identify regulatory sites in genomic sequence.
PubMed Identifier: 21557084
author list: Field Y, Sharon E, Segal E
published in: Sub-cellular biochemistry
information resource reference: How transcription factors identify regulatory sites in genomic sequence. Subcell Biochem. 2011; 52:193-204.
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The DNA-encoded nucleosome organization of a eukaryotic genome.
PubMed Identifier: 19092803
author list: Kaplan N, Moore IK, Fondufe-Mittendorf Y, Gossett AJ, Tillo D, Field Y, LeProust EM, Hughes TR, Lieb JD, Widom J, Segal E
published in: Nature
information resource reference: The DNA-encoded nucleosome organization of a eukaryotic genome. Nature. 2009 Mar 19; 458(7236):362-6.
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High nucleosome occupancy is encoded at human regulatory sequences.
PubMed Identifier: 20161746
author list: Tillo D, Kaplan N, Moore IK, Fondufe-Mittendorf Y, Gossett AJ, Field Y, Lieb JD, Widom J, Segal E, Hughes TR
published in: PloS one
information resource reference: High nucleosome occupancy is encoded at human regulatory sequences. PLoS One. 2010 Feb 09; 5(2):e9129.
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Nucleosome sequence preferences influence in vivo nucleosome organization.
PubMed Identifier: 20683473
author list: Kaplan N, Moore I, Fondufe-Mittendorf Y, Gossett AJ, Tillo D, Field Y, Hughes TR, Lieb JD, Widom J, Segal E
published in: Nature structural & molecular biology
information resource reference: Nucleosome sequence preferences influence in vivo nucleosome organization. Nat Struct Mol Biol. 2010 Aug; 17(8):918-20.
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Gene expression divergence in yeast is coupled to evolution of DNA-encoded nucleosome organization.
PubMed Identifier: 19252487
author list: Field Y, Fondufe-Mittendorf Y, Moore IK, Mieczkowski P, Kaplan N, Lubling Y, Lieb JD, Widom J, Segal E
published in: Nature genetics
information resource reference: Gene expression divergence in yeast is coupled to evolution of DNA-encoded nucleosome organization. Nat Genet. 2009 Apr; 41(4):438-45.
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Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells.
PubMed Identifier: 18344985
author list: Minsky N, Shema E, Field Y, Schuster M, Segal E, Oren M
published in: Nature cell biology
information resource reference: Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells. Nat Cell Biol. 2008 Apr; 10(4):483-8.
journal title abbreviation: Nat Cell Biol
publication date: 2008-03-16T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

p53 binds preferentially to genomic regions with high DNA-encoded nucleosome occupancy.
PubMed Identifier: 20716666
author list: Lidor Nili E, Field Y, Lubling Y, Widom J, Oren M, Segal E
published in: Genome research
information resource reference: p53 binds preferentially to genomic regions with high DNA-encoded nucleosome occupancy. Genome Res. 2010 Oct; 20(10):1361-8.
journal title abbreviation: Genome Res
publication date: 2010-08-17T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Distinct modes of regulation by chromatin encoded through nucleosome positioning signals.
PubMed Identifier: 18989395
author list: Field Y, Kaplan N, Fondufe-Mittendorf Y, Moore IK, Sharon E, Lubling Y, Widom J, Segal E
published in: PLoS computational biology
information resource reference: Distinct modes of regulation by chromatin encoded through nucleosome positioning signals. PLoS Comput Biol. 2008 Nov; 4(11):e1000216.
journal title abbreviation: PLoS Comput Biol
publication date: 2008-11-07T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Two DNA-encoded strategies for increasing expression with opposing effects on promoter dynamics and transcriptional noise.
PubMed Identifier: 23403035
author list: Dadiani M, van Dijk D, Segal B, Field Y, Ben-Artzi G, Raveh-Sadka T, Levo M, Kaplow I, Weinberger A, Segal E
published in: Genome research
information resource reference: Two DNA-encoded strategies for increasing expression with opposing effects on promoter dynamics and transcriptional noise. Genome Res. 2013 Jun; 23(6):966-76.
journal title abbreviation: Genome Res
publication date: 2013-02-12T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 95490
type: Authorship
author rank in publication: 1
linked author: Field, Yair
linked information resource: Detection of human adaptation during the past 2000 years.

Detection of human adaptation during the past 2000 years.
PubMed Identifier: 27738015
author list: Field Y, Boyle EA, Telis N, Gao Z, Gaulton KJ, Golan D, Yengo L, Rocheleau G, Froguel P, McCarthy MI, Pritchard JK
published in: Science (New York, N.Y.)
information resource reference: Detection of human adaptation during the past 2000 years. Science. 2016 11 11; 354(6313):760-764.
journal title abbreviation: Science
publication date: 2016-10-13T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource