Reem Jan is a clinical Associate Professor at the University of Chicago, with extensive experience in the diagnosis and management of rheumatic diseases in a tertiary care setting. She graduated from St George's medical school in London UK, completed internal medicine residency and rheumatology fellowship at the University of Michigan in Ann Arbor before her academic appointment in Chicago in 2012. She has developed particular expertise in spondyloarthritis, with focus on ankylosing spondylitis and psoriatic arthritis. She provides specialist rheumatology care for patients followed at the University of Chicago Inflammatory Bowel Disease Center, which forms her primary research interest. She also has a senior administrative role within the Department of Medicine as Associate Chief of Clinical Affairs for the section of Rheumatology.
Approach to Patients with Suspected Rheumatic Disease. Prim Care. 2018 Jun; 45(2):169-180.
Approach to Patients with Suspected Rheumatic Disease.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
IgG-4-Related Hypophysitis Treated With Rituximab: Case Report. J Clin Rheumatol. 2021 Dec 01; 27(8S):S340-S341.
IgG-4-Related Hypophysitis Treated With Rituximab: Case Report.
Gourh P, Remmers EF, Boyden SE, Alexander T, Morgan ND, Shah AA, Mayes MD, Doumatey A, Bentley AR, Shriner D, Domsic RT, Medsger TA, Steen VD, Ramos PS, Silver RM, Korman B, Varga J, Schiopu E, Khanna D, Hsu V, Gordon JK, Saketkoo LA, Gladue H, Kron B, Criswell LA, Derk CT, Bridges SL, Shanmugam VK, Kolstad KD, Chung L, Jan R, Bernstein EJ, Goldberg A, Trojanowski M, Kafaja S, Maksimowicz-McKinnon KM, Mullikin JC, Adeyemo A, Rotimi C, Boin F, Kastner DL, Wigley FM
Arthritis & rheumatology (Hoboken, N.J.)
Brief Report: Whole-Exome Sequencing to Identify Rare Variants and Gene Networks That Increase Susceptibility to Scleroderma in African Americans. Arthritis Rheumatol. 2018 10; 70(10):1654-1660.
Brief Report: Whole-Exome Sequencing to Identify Rare Variants and Gene Networks That Increase Susceptibility to Scleroderma in African Americans.
Morgan ND, Shah AA, Mayes MD, Domsic RT, Medsger TA, Steen VD, Varga J, Carns M, Ramos PS, Silver RM, Schiopu E, Khanna D, Hsu V, Gordon JK, Gladue H, Saketkoo LA, Criswell LA, Derk CT, Trojanowski MA, Shanmugam VK, Chung L, Valenzuela A, Jan R, Goldberg A, Remmers EF, Kastner DL, Wigley FM, Gourh P, Boin F
Clinical and serological features of systemic sclerosis in a multicenter African American cohort: Analysis of the genome research in African American scleroderma patients clinical database. Medicine (Baltimore). 2017 Dec; 96(51):e8980.
Clinical and serological features of systemic sclerosis in a multicenter African American cohort: Analysis of the genome research in African American scleroderma patients clinical database.
Gourh P, Safran SA, Alexander T, Boyden SE, Morgan ND, Shah AA, Mayes MD, Doumatey A, Bentley AR, Shriner D, Domsic RT, Medsger TA, Ramos PS, Silver RM, Steen VD, Varga J, Hsu V, Saketkoo LA, Schiopu E, Khanna D, Gordon JK, Kron B, Criswell LA, Gladue H, Derk CT, Bernstein EJ, Bridges SL, Shanmugam VK, Kolstad KD, Chung L, Kafaja S, Jan R, Trojanowski M, Goldberg A, Korman BD, Steinbach PJ, Chandrasekharappa SC, Mullikin JC, Adeyemo A, Rotimi C, Wigley FM, Kastner DL, Boin F, Remmers EF
Proceedings of the National Academy of Sciences of the United States of America
HLA and autoantibodies define scleroderma subtypes and risk in African and European Americans and suggest a role for molecular mimicry. Proc Natl Acad Sci U S A. 2020 01 07; 117(1):552-562.
HLA and autoantibodies define scleroderma subtypes and risk in African and European Americans and suggest a role for molecular mimicry.
Psychiatry and Behavioral Neuroscience-Child Psychiatry
Psychiatry and Behavioral Neuroscience-Research
Jan RK, Alsheikh-Ali A, Mulla AA, Sulaiman K, Panduranga P, Al-Mahmeed W, Bazargani N, Al-Suwaidi J, Al-Jarallah M, Al-Motarreb A, Salam A, Al-Zakwani I
Outcomes of guideline-based medical therapy in patients with acute heart failure and reduced left ventricular ejection fraction: Observations from the Gulf acute heart failure registry (Gulf CARE). Medicine (Baltimore). 2022 Jun 10; 101(23):e29452.
Outcomes of guideline-based medical therapy in patients with acute heart failure and reduced left ventricular ejection fraction: Observations from the Gulf acute heart failure registry (Gulf CARE).
Ahmad F, Oyen F, Jan R, Budde U, Schneppenheim R, Saxena R
Haemophilia : the official journal of the World Federation of Hemophilia
Germline de novo mutations and linkage markers vs. DNA sequencing for carrier detection in von Willebrand disease. Haemophilia. 2014 Jul; 20(4):e311-7.
Germline de novo mutations and linkage markers vs. DNA sequencing for carrier detection in von Willebrand disease.
Parent-Child Interaction Therapy (PCIT) Program
Checkpoint Inhibitor-Associated Scleroderma and Scleroderma Mimics. Pharmaceuticals (Basel). 2023 Feb 08; 16(2).
Checkpoint Inhibitor-Associated Scleroderma and Scleroderma Mimics.
Jan RK, Lin JC, Lee H, Sheridan JL, Kydd RR, Kirk IJ, Russell BR
Determining the subjective effects of TFMPP in human males. Psychopharmacology (Berl). 2010 Aug; 211(3):347-53.
Determining the subjective effects of TFMPP in human males.
Investigating the microstructural and neurochemical environment within the basal ganglia of current methamphetamine abusers. Drug Alcohol Depend. 2015 Apr 01; 149:122-7.
Investigating the microstructural and neurochemical environment within the basal ganglia of current methamphetamine abusers.
Lin JC, Jan RK, Lee H, Jensen MA, Kydd RR, Russell BR
Determining the subjective and physiological effects of BZP combined with TFMPP in human males. Psychopharmacology (Berl). 2011 Apr; 214(3):761-8.
Determining the subjective and physiological effects of BZP combined with TFMPP in human males.
Sheridan J, Kelly F, Basheer M, Jan R, Lee A
The International journal of pharmacy practice
Can I help you? A qualitative study of pharmacist and pharmacy assistant views on the role of pharmacy assistants in New Zealand. Int J Pharm Pract. 2011 Aug; 19(4):228-35.
Can I help you? A qualitative study of pharmacist and pharmacy assistant views on the role of pharmacy assistants in New Zealand.
Jan RK, Lin JC, McLaren DG, Kirk IJ, Kydd RR, Russell BR
The effects of methylphenidate on cognitive control in active methamphetamine dependence using functional magnetic resonance imaging. Front Psychiatry. 2014; 5:20.
The effects of methylphenidate on cognitive control in active methamphetamine dependence using functional magnetic resonance imaging.
Functional and structural brain changes associated with methamphetamine abuse. Brain Sci. 2012 Oct 01; 2(4):434-82.
Functional and structural brain changes associated with methamphetamine abuse.
Jan RK, Lin JC, Miles SW, Kydd RR, Russell BR
Striatal volume increases in active methamphetamine-dependent individuals and correlation with cognitive performance. Brain Sci. 2012 Oct 30; 2(4):553-72.
Striatal volume increases in active methamphetamine-dependent individuals and correlation with cognitive performance.
Subjective effects in humans following administration of party pill drugs BZP and TFMPP alone and in combination. Drug Test Anal. 2011 Sep; 3(9):582-5.
Subjective effects in humans following administration of party pill drugs BZP and TFMPP alone and in combination.
Hong SJ, Dalal RS, Kuhn KA, Stahly A, Scott FI, Click BH, Way A, Malik F, Davis JM, Shmais M, Raffals LE, Silfen A, Rubin DT, Dharia I, Bhattacharya A, Moghaddam B, Mains T, Kurland J, Patel S, Weisman MH, Ermann J, Jan R
The American journal of gastroenterology
Prevalence and Risk Factors of Spondyloarthritis Symptoms in a US-Based Multicenter Cohort of Patients With Inflammatory Bowel Disease. Am J Gastroenterol. 2025 Oct 01; 120(10):2330-2338.
Prevalence and Risk Factors of Spondyloarthritis Symptoms in a US-Based Multicenter Cohort of Patients With Inflammatory Bowel Disease.
Ghelani H, Adrian TE, Ho SB, Akhras J, Azar AJ, Jan RK
Contemporary clinical trials communications
Study protocol for a pilot randomized, double-blind, placebo-controlled trial to investigate the anti-inflammatory effects of Frondanol in adults with inflammatory bowel disease. Contemp Clin Trials Commun. 2023 Feb; 31:101046.
Study protocol for a pilot randomized, double-blind, placebo-controlled trial to investigate the anti-inflammatory effects of Frondanol in adults with inflammatory bowel disease.
Kaddoura R, Ghelani H, Alqutami F, Altaher H, Hachim M, Jan RK
Identification of Specific Biomarkers and Pathways in the Treatment Response of Infliximab for Inflammatory Bowel Disease: In-Silico Analysis. Life (Basel). 2023 Mar 02; 13(3).
Identification of Specific Biomarkers and Pathways in the Treatment Response of Infliximab for Inflammatory Bowel Disease: In-Silico Analysis.
Screening for Spondyloarthritis in Patients with Inflammatory Bowel Disease - SPARTAN 2024 Annual Meeting Proceedings. Curr Rheumatol Rep. 2025 Feb 01; 27(1):17.
Screening for Spondyloarthritis in Patients with Inflammatory Bowel Disease - SPARTAN 2024 Annual Meeting Proceedings.
Ermann J, Hong SJ, Stahly A, Dalal RS, Malik F, Scott FI, Click B, Way A, Davis JM, Shmais M, Raffals LE, Jan R, Silfen A, Rubin DT, Dharia I, Bhattacharya A, Moghaddam B, Mains T, Kurland JE, Patel S, Kuhn KA, Weisman MH
Frequency of Spondyloarthritis Symptoms Among US Patients With Inflammatory Bowel Disease: A Cross-Sectional Multi-Center Study. Arthritis Care Res (Hoboken). 2025 Jun; 77(6):777-784.
Frequency of Spondyloarthritis Symptoms Among US Patients With Inflammatory Bowel Disease: A Cross-Sectional Multi-Center Study.