Regulatory defects in Cbl and mitogen-activated protein kinase (extracellular signal-related kinase) pathways cause persistent hyperexpression of CD40 ligand in human lupus T cells.

Regulatory defects in Cbl and mitogen-activated protein kinase (extracellular signal-related kinase) pathways cause persistent hyperexpression of CD40 ligand in human lupus T cells. J Immunol. 2000 Dec 01; 165(11):6627-34.

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subject areas

Abatacept
Adolescent
Adult
Antigens, CD
Antigens, Differentiation
Calcineurin
CD28 Antigens
CD40 Ligand
Cell Line
Clonal Anergy
CTLA-4 Antigen
DNA-Binding Proteins
Enzyme Activation
Female
Humans
Immunity, Innate
Immunoconjugates
Immunologic Memory
Interleukin-2
Lupus Erythematosus, Systemic
Male
MAP Kinase Signaling System
Middle Aged
Mitogen-Activated Protein Kinases
NFATC Transcription Factors
Nuclear Proteins
Phosphorylation
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-cbl
Receptors, Antigen, T-Cell
T-Lymphocytes
T-Lymphocytes, Helper-Inducer
Transcription Factors
Tyrosine
Ubiquitin-Protein Ligases

authors with profiles

Megan Mcnerney