15324815Lee YS, Bergson P, He WS, Mrksich M, Tang WJChemistry & biologyAdenylyl Cyclase Inhibitors; Adenylyl Cyclases; Calmodulin; Drug Evaluation, Preclinical; Sulfonamides; ThiazolesAnimals; Anthrax; Antigens, Bacterial; Bacillus anthracis; Bacterial Toxins; Cell Line; Cricetinae; Ligands; Mice; Models, Molecular; Protein Binding; Protein Conformation; Structure-Activity Relationship; Substrate Specificity; Surface Plasmon ResonanceDiscovery of a small molecule that inhibits the interaction of anthrax edema factor with its cellular activator, calmodulin. Chem Biol. 2004 Aug; 11(8):1139-46.Chem Biol2004-08-01T00:00:002004Discovery of a small molecule that inhibits the interaction of anthrax edema factor with its cellular activator, calmodulin.prns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkAnchorTextlink anchor textvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleURLLinkvivo:webpagewebpagerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD000262Chemicals & Drugs371000.951998Adenylyl CyclasesD000818Living Beings1457265180.249646AnimalsD002147Chemicals & Drugs26500.966434CalmodulinD000881Disorders12300.97921AnthraxD000942Chemicals & Drugs481340.931015Antigens, BacterialD001408Living Beings19730.93516Bacillus anthracisD001427Chemicals & Drugs471110.929796Bacterial ToxinsD004353Procedures831030.963851Drug Evaluation, PreclinicalD008958Concepts & Ideas24512840.706981Models, MolecularD006224Living Beings1465600.916018CricetinaeD008024Chemicals & Drugs2034330.884665LigandsD011485PhenomenaPhysiology42014540.739297Protein BindingD011487Concepts & Ideas1998810.794238Protein ConformationBen May Department of Cancer ResearchD051379Living Beings980113130.368427MiceD013329Concepts & Ideas1794080.910997Structure-Activity RelationshipD013449Chemicals & Drugs1502990.834203SulfonamidesD013379Concepts & Ideas1463470.916579Substrate SpecificityD013844Chemicals & Drugs681310.925773ThiazolesD020349Procedures27460.988316Surface Plasmon ResonanceD002460Anatomy54024660.697119Cell LineD0000679563100.99598Adenylyl Cyclase Inhibitorshttp://voices.uchicago.edu/wtang-lab/Wei-Jen Tang laboratory siteUniversity of ChicagoWei-JenTangWei-Jen Tang41.78927490000000-87.60125000000000957Tang, Wei-JenProfessortrue1ProfessorProfessorAuthorship 5547750.2560010.2560011authors10.2521has subject area