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A novel thyroid hormone receptor-beta mutation that fails to bind nuclear receptor corepressor in a patient as an apparent cause of severe, predominantly pituitary resistance to thyroid hormone.
PropertyValue
has minor subject area list Amino Acid Sequence; Child; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Fibroblasts; Genes, Reporter; Histone Acetyltransferases; Humans; Infant, Newborn; Male; Molecular Sequence Data; Nuclear Receptor Co-Repressor 1; Nuclear Receptor Co-Repressor 2; Nuclear Receptor Coactivator 1; Plasmids; Transcription Factors; Transfection
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  • Nuclear Receptor Co Repressor 1