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Dignam, James J.
One or more keywords matched the following properties of Dignam, James J.
PropertyValue
keywords survival analysis
overview Dr. Dignam's primary research involves the design, conduct, and analysis of cancer clinical trials, including early development (phase I), pilot efficacy and safety (phase II), and definitive evaluation (phase III) trials. He is the Executive Director of the Statistics and Data Management Center for NRG Oncology, a National Cancer Institute sponsored multi-center clinical trials group with over 500 recruitment sites in North America and beyond and over 100 active clinical trials. Dr. Dignam's methodology interests include trial monitoring and early stopping rules, competing risks, hazard function estimation, and prognostic modeling. He also has engaged in and led investigations into sociodemographic factors such as race/ethnicity and BMI/obesity on cancer prognosis and treatment response. Courses taught include introductory biostatistics, clinical trials, survival analysis, and regression modeling methods.
One or more keywords matched the following items that are connected to Dignam, James J.
Item TypeName
Concept Survival Analysis
Academic Article Tamoxifen and chemotherapy for lymph node-negative, estrogen receptor-positive breast cancer.
Academic Article Methods for bounding the marginal survival distribution.
Academic Article Prognosis and treatment of patients with breast tumors of one centimeter or less and negative axillary lymph nodes.
Academic Article Prevention of invasive breast cancer in women with ductal carcinoma in situ: an update of the National Surgical Adjuvant Breast and Bowel Project experience.
Academic Article Outcomes among African-Americans and Caucasians in colon cancer adjuvant therapy trials: findings from the National Surgical Adjuvant Breast and Bowel Project.
Academic Article Benefits and costs of interventions to improve breast cancer outcomes in African American women.
Academic Article Toward optimal screening strategies for older women. Costs, benefits, and harms of breast cancer screening by age, biology, and health status.
Academic Article Obesity, tamoxifen use, and outcomes in women with estrogen receptor-positive early-stage breast cancer.
Academic Article Colorectal cancer and race: understanding the differences in outcomes between African Americans and whites.
Academic Article Effects of obesity and race on prognosis in lymph node-negative, estrogen receptor-negative breast cancer.
Academic Article Long-term outcomes of invasive ipsilateral breast tumor recurrences after lumpectomy in NSABP B-17 and B-24 randomized clinical trials for DCIS.
Academic Article Multiple imputation methods for inference on cumulative incidence with missing cause of failure.
Academic Article Conditional survival and the choice of conditioning set for patients with colon cancer: an analysis of NSABP trials C-03 through C-07.
Academic Article Diffusing capacity predicts long-term survival after lung resection for cancer.
Academic Article Estimating breast cancer-specific and other-cause mortality in clinical trial and population-based cancer registry cohorts.
Academic Article Tamoxifen, radiation therapy, or both for prevention of ipsilateral breast tumor recurrence after lumpectomy in women with invasive breast cancers of one centimeter or less.
Academic Article A randomized trial of bevacizumab for newly diagnosed glioblastoma.
Academic Article Bayesian approach for flexible modeling of semicompeting risks data.
Academic Article Flexible modeling of the hazard rate and treatment effects in long-term survival studies.
Academic Article Metastasis-Free Survival Is a Strong Surrogate of Overall Survival in Localized Prostate Cancer.
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  • Survival Analysis