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Dignam, James J.
One or more keywords matched the following properties of Dignam, James J.
PropertyValue
keywords modeling
overview Dr. Dignam's primary research involves the design, conduct, and analysis of cancer clinical trials, including early development (phase I), pilot efficacy and safety (phase II), and definitive evaluation (phase III) trials. He is the Executive Director of the Statistics and Data Management Center for NRG Oncology, a National Cancer Institute sponsored multi-center clinical trials group with over 500 recruitment sites in North America and beyond and over 100 active clinical trials. Dr. Dignam's methodology interests include trial monitoring and early stopping rules, competing risks, hazard function estimation, and prognostic modeling. He also has engaged in and led investigations into sociodemographic factors such as race/ethnicity and BMI/obesity on cancer prognosis and treatment response. Courses taught include introductory biostatistics, clinical trials, survival analysis, and regression modeling methods.
One or more keywords matched the following items that are connected to Dignam, James J.
Item TypeName
Concept Models, Theoretical
Concept Proportional Hazards Models
Concept Models, Econometric
Concept Models, Statistical
Concept Logistic Models
Concept Disease Models, Animal
Academic Article Methods for bounding the marginal survival distribution.
Academic Article Pathologic findings from the National Surgical Adjuvant Breast Project (NSABP) eight-year update of Protocol B-17: intraductal carcinoma.
Academic Article Benefits and costs of interventions to improve breast cancer outcomes in African American women.
Academic Article Is patient travel distance associated with survival on phase II clinical trials in oncology?
Academic Article Statistical considerations in assessing molecular markers for cancer prognosis and treatment efficacy.
Academic Article Mammographic density and breast cancer after ductal carcinoma in situ.
Academic Article Toward optimal screening strategies for older women. Costs, benefits, and harms of breast cancer screening by age, biology, and health status.
Academic Article Effects of obesity and race on prognosis in lymph node-negative, estrogen receptor-negative breast cancer.
Academic Article Comments on: Yin W, Di G, Zhou L, Lu J, Liu G, Wu J, Shen K, Han Q, Shen Z, Shao Z. Time-varying pattern of recurrence risk for Chinese breast cancer patients.
Academic Article A missing data approach to semi-competing risks problems.
Academic Article Conditional survival and the choice of conditioning set for patients with colon cancer: an analysis of NSABP trials C-03 through C-07.
Academic Article Outcomes among black patients with stage II and III colon cancer receiving chemotherapy: an analysis of ACCENT adjuvant trials.
Academic Article Colorectal cancer model of health disparities: understanding mortality differences in minority populations.
Academic Article The use and interpretation of competing risks regression models.
Academic Article Tamoxifen, radiation therapy, or both for prevention of ipsilateral breast tumor recurrence after lumpectomy in women with invasive breast cancers of one centimeter or less.
Academic Article Semiparametric models for cumulative incidence functions.
Academic Article Glioma-associated oncogene family zinc finger 1 expression and metastasis in patients with head and neck squamous cell carcinoma treated with radiation therapy (RTOG 9003).
Academic Article Race and the prognostic influence of p53 in women with breast cancer.
Academic Article NCI-RTOG translational program strategic guidelines for the early-stage development of radiosensitizers.
Academic Article Multiple imputation methods for nonparametric inference on cumulative incidence with missing cause of failure.
Academic Article A randomized trial of bevacizumab for newly diagnosed glioblastoma.
Academic Article Bayesian Hierarchical Multiresolution Hazard Model for the Study of Time-Dependent Failure Patterns in Early Stage Breast Cancer.
Academic Article Bayesian approach for flexible modeling of semicompeting risks data.
Academic Article Hormone replacement therapy and breast cancer: heterogeneous risks by race, weight, and breast density.
Academic Article A tissue biomarker-based model that identifies patients with a high risk of distant metastasis and differential survival by length of androgen deprivation therapy in RTOG protocol 92-02.
Academic Article Variation over time and interdependence between disease progression and death among patients with glioblastoma on RTOG 0525.
Academic Article Joint modelling of longitudinal and multi-state processes: application to clinical progressions in prostate cancer.
Academic Article A Multiresolution Hazard Model for Multicenter Survival Studies: Application to Tamoxifen Treatment in Early Stage Breast Cancer.
Academic Article Flexible modeling of the hazard rate and treatment effects in long-term survival studies.
Academic Article Investigating the Effect of Reirradiation or Systemic Therapy in Patients With Glioblastoma After Tumor Progression: A Secondary Analysis of NRG Oncology/Radiation Therapy Oncology Group Trial 0525.
Academic Article Characteristics of Participation in Patient-Reported Outcomes and Electronic Data Capture Components of NRG Oncology Clinical Trials.
Search Criteria
  • prognostic
  • modeling