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Storb, Ursula

One or more keywords matched the following items that are connected to Storb, Ursula

Item Type	Name
Concept	Genes, Immunoglobulin
Academic Article	The molecular basis of somatic hypermutation of immunoglobulin genes.
Academic Article	Influence of CpG methylation and target spacing on V(D)J recombination in a transgenic substrate.
Academic Article	The mechanism of somatic hypermutation studied with transgenic and transfected target genes.
Academic Article	Somatic hypermutation of immunoglobulin genes is linked to transcription initiation.
Academic Article	N region diversity of a transgenic substrate in fetal and adult lymphoid cells.
Academic Article	Progress in understanding the mechanism and consequences of somatic hypermutation.
Academic Article	Somatic hypermutation of an artificial test substrate within an Ig kappa transgene.
Academic Article	B lymphocytes of xeroderma pigmentosum or Cockayne syndrome patients with inherited defects in nucleotide excision repair are fully capable of somatic hypermutation of immunoglobulin genes.
Academic Article	The inactivation of the XP-C gene does not affect somatic hypermutation or class switch recombination of immunoglobulin genes.
Academic Article	Immunoglobulin transgenes as targets for somatic hypermutation.
Academic Article	The composition of coding joints formed in V(D)J recombination is strongly affected by the nucleotide sequence of the coding ends and their relationship to the recombination signal sequences.
Academic Article	Rearrangement and expression of immunoglobulin genes in transgenic mice.
Academic Article	Somatic hypermutation of immunoglobulin genes is linked to transcription.
Academic Article	Mef2 proteins, required for muscle differentiation, bind an essential site in the Ig lambda enhancer.
Academic Article	Cis-acting sequences that affect somatic hypermutation of Ig genes.
Academic Article	Somatic hypermutation of immunoglobulin and non-immunoglobulin genes.
Academic Article	Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes.
Academic Article	Hypomethylation is necessary but not sufficient for V(D)J recombination within a transgenic substrate.
Academic Article	The TATA binding protein, c-Myc and survivin genes are not somatically hypermutated, while Ig and BCL6 genes are hypermutated in human memory B cells.
Academic Article	The role of DNA repair in somatic hypermutation of immunoglobulin genes.
Academic Article	Insertion of phosphoglycerine kinase (PGK)-neo 5' of Jlambda1 dramatically enhances VJlambda1 rearrangement.
Academic Article	Signal joint formation is inhibited in murine scid preB cells and fibroblasts in substrates with homopolymeric coding ends.
Academic Article	Effects of sequence and structure on the hypermutability of immunoglobulin genes.
Academic Article	Analysis of a T cell receptor gene as a target of the somatic hypermutation mechanism.
Academic Article	A novel cytidine deaminase affects antibody diversity.
Academic Article	A point mutation in the constant region of Ig lambda1 prevents normal B cell development due to defective BCR signaling.
Academic Article	A novel cytidine deaminase AIDs in the delivery of error-prone polymerases to immunoglobulin genes.
Academic Article	Mutation pattern of immunoglobulin transgenes is compatible with a model of somatic hypermutation in which targeting of the mutator is linked to the direction of DNA replication.
Academic Article	Ig gene somatic hypermutation in mice defective for DNA polymerase delta proofreading.
Academic Article	Identification and localization of an enhancer for the human lambda L chain Ig gene complex.
Academic Article	Immunology. Autoreactive B cells migrate into T cell territory.
Academic Article	Delay of early B-lymphocyte development by gamma 2b immunoglobulin transgene: effect on differentiation-specific molecules.
Academic Article	The published data.
Academic Article	The contested role of uracil DNA glycosylase in immunoglobulin gene diversification.
Academic Article	A novel enhancer in the immunoglobulin lambda locus is duplicated and functionally independent of NF kappa B.
Academic Article	Brca1 in immunoglobulin gene conversion and somatic hypermutation.
Academic Article	Cloning of a gamma 2b gene encoding anti-Pseudomonas aeruginosa H chains and its introduction into the germ line of mice.
Academic Article	Elevated PC responsive B cells and anti-PC antibody production in transgenic mice harboring anti-PC immunoglobulin genes.
Academic Article	Quantitation of immunoglobulin genes by nucleic acid hybridization with RNA from myeloma and spleen microsomes.
Academic Article	Misalignment of V and J gene segments resulting in a nonfunctional immunoglobulin gene.
Academic Article	Comparison of different rearranged immunoglobulin kappa genes of a myeloma by electronmicroscopy and restriction mapping of cloned DNA: implications for "allelic exclusion".
Academic Article	Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in kappa transgenic mice.
Academic Article	Rearrangement of immunoglobulin genes.
Academic Article	Ig lambda-producing B cells do not show feedback inhibition of gene rearrangement.
Academic Article	Analysis of immunoglobulin genes: DNA/RNA hybridization with immunoglobulin kappa-chain mRNA and isolation and translation of hybridized RNA.
Academic Article	Immunoglobulin genes in DNA restriction fragments.
Academic Article	Immunoglobulin gene 'remnant' DNA--implications for antibody gene recombination.
Academic Article	Nucleosome stability dramatically impacts the targeting of somatic hypermutation.
Academic Article	Association of two different repetitive DNA elements near immunoglobulin light chain genes.
Academic Article	lambda 5, but not mu, is required for B cell maturation in a unique gamma 2b transgenic mouse line.
Academic Article	Transgenic mice with immunoglobulin genes.
Academic Article	The order and orientation of mouse lambda-genes explain lambda-rearrangement patterns.
Academic Article	Fusion of a scid pre-B cells with a wild type (myeloma) B cell results in correct rearrangement of a V(D)J recombination substrate.
Academic Article	Myeloma with multiple rearranged immunoglobulin kappa genes: only one kappa gene codes for kappa chains.
Academic Article	Expression of a microinjected immunoglobulin gene in the spleen of transgenic mice.
Academic Article	Sequences of immunoglobulin lambda 1 genes in a lambda 1 defective mouse strain.
Academic Article	Evolution of mouse immunoglobulin lambda genes.
Academic Article	Immunoglobulin gamma 2b transgenes inhibit heavy chain gene rearrangement, but cannot promote B cell development.
Academic Article	Attracting AID to targets of somatic hypermutation.
Academic Article	Methylation patterns of immunoglobulin genes in lymphoid cells: correlation of expression and differentiation with undermethylation.
Academic Article	Molecular aspects of somatic hypermutation of immunoglobulin genes.
Academic Article	The 3' Igkappa enhancer contains RNA polymerase II promoters: implications for endogenous and transgenic kappa gene expression.
Academic Article	DNA polymerases in immunity: profiting from errors.
Academic Article	Immunoglobulin genes: generating diversity with AID and UNG.
Academic Article	Precursors of both conventional and Ly-1 B cells can escape feedback inhibition of Ig gene rearrangement.
Academic Article	The very 5' end and the constant region of Ig genes are spared from somatic mutation because AID does not access these regions.
Academic Article	Targeting of AID to immunoglobulin genes.
Academic Article	Inhibition of immunoglobulin gene rearrangement by the expression of a lambda 2 transgene.
Academic Article	The pattern of somatic hypermutation of Ig genes is altered when p53 is inactivated.
Academic Article	Expression of immunoglobulin genes in transgenic mice and transfected cells.
Academic Article	Feedback inhibition of immunoglobulin gene rearrangement by membrane mu, but not by secreted mu heavy chains.
Academic Article	B cells expressing Ig transgenes respond to a T-dependent antigen only in the presence of Ia-compatible T cells.
Academic Article	Immunoglobulin gene rearrangements in hybridoma cells.
Academic Article	Mapping of immunoglobulin variable region genes: relationship to the 'deletion' model of immunoglobulin gene rearrangement.
Academic Article	Evidence for multiple immunoglobulin genes.
Grant	CONTROL OF IMMUNOGLOBULIN SYNTHESIS
Grant	CONTROL OF IMMUNOGLOBULIN SYNTHESIS
Grant	EXPRESSION OF IMMUNOGLOBULIN GENES IN TRANSGENIC MICE
Grant	CONTROL OF IMMUNOGLOBULIN SYNTHESIS
Grant	EXPRESSION OF IMMUNOGLOBULIN GENES
Grant	MUTATION OF IG GENES
Grant	Mechanism of Immunoglobulin Hypermutation
Grant	AID in somatic mutation of immunoglobulin genes
Grant	Mechanism of Immunoglobulin Hypermutation
Grant	Immunoglobulin Somatic Mutation
Grant	EXPRESSION OF IMMUNOGLOBULIN GENES

Search Criteria

Genes Immunoglobulin