| Item Type | Name |
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Concept
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Models, Molecular
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Concept
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Models, Genetic
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Concept
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Models, Theoretical
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Concept
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Linear Models
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Concept
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Proportional Hazards Models
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Concept
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Logistic Models
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Concept
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Xenograft Model Antitumor Assays
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Concept
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Disease Models, Animal
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Concept
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Models, Biological
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Academic Article
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Activation of hematopoietic growth factor signal transduction pathways by the human oncogene BCR/ABL.
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Academic Article
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Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition.
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Academic Article
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Molecular alterations in lung cancer. Impact on prognosis.
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Academic Article
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c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention.
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Academic Article
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A selective small molecule inhibitor of c-Met, PHA665752, inhibits tumorigenicity and angiogenesis in mouse lung cancer xenografts.
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Academic Article
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Epidermal growth factor receptor - mediated signal transduction in the development and therapy of gliomas.
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Academic Article
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The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma.
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Academic Article
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Role of c-Met in cancer: emphasis on lung cancer.
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Academic Article
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Ethnic differences and functional analysis of MET mutations in lung cancer.
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Academic Article
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c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion.
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Academic Article
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The clinical presentation and prognostic factors for intrahepatic and extrahepatic cholangiocarcinoma in a tertiary care centre.
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Academic Article
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The novel role of the mu opioid receptor in lung cancer progression: a laboratory investigation.
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Academic Article
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Lysophosphatidic acid modulates c-Met redistribution and hepatocyte growth factor/c-Met signaling in human bronchial epithelial cells through PKC delta and E-cadherin.
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Academic Article
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Fyn is downstream of the HGF/MET signaling axis and affects cellular shape and tropism in PC3 cells.
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Academic Article
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Prognostic value of metabolic tumor burden on 18F-FDG PET in nonsurgical patients with non-small cell lung cancer.
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Academic Article
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Overexpression of the µ-opioid receptor in human non-small cell lung cancer promotes Akt and mTOR activation, tumor growth, and metastasis.
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Academic Article
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MET, HGF, EGFR, and PXN gene copy number in lung cancer using DNA extracts from FFPE archival samples and prognostic significance.
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Academic Article
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Role of protein kinase C ß and vascular endothelial growth factor receptor in malignant pleural mesothelioma: Therapeutic implications and the usefulness of Caenorhabditis elegans model organism.
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Academic Article
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Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancer.
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Academic Article
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Prognostic significance of angiogenesis and angiogenic growth factors in nonsmall cell lung cancer.
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Academic Article
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Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis.
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Academic Article
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Targeting ALK: a promising strategy for the treatment of non-small cell lung cancer, non-Hodgkin's lymphoma, and neuroblastoma.
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Academic Article
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CD44 regulates hepatocyte growth factor-mediated vascular integrity. Role of c-Met, Tiam1/Rac1, dynamin 2, and cortactin.
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Academic Article
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C. elegans as a model organism for in vivo screening in cancer: effects of human c-Met in lung cancer affect C. elegans vulva phenotypes.
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Academic Article
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RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma.
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Academic Article
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Degradation and regurgitation of extracellular proteins by cultured mouse peritoneal macrophages and baby hamster kidney fibroblasts. Kinetic evidence that the transfer of proteins to lysosomes is not irreversible.
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Academic Article
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Critical role for the receptor tyrosine kinase EPHB4 in esophageal cancers.
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Academic Article
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The EphB4 receptor tyrosine kinase promotes lung cancer growth: a potential novel therapeutic target.
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Academic Article
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Critical role of S1PR1 and integrin ß4 in HGF/c-Met-mediated increases in vascular integrity.
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Academic Article
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EphB4 as a therapeutic target in mesothelioma.
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Academic Article
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MET and PI3K/mTOR as a potential combinatorial therapeutic target in malignant pleural mesothelioma.
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Academic Article
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Dramatic antitumor effects of the dual MET/RON small-molecule inhibitor LY2801653 in non-small cell lung cancer.
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Academic Article
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Geographic variation in radiologist capacity and widespread implementation of lung cancer CT screening.
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Academic Article
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AXL mediates resistance to cetuximab therapy.
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Academic Article
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Overcoming acquired resistance to cetuximab by dual targeting HER family receptors with antibody-based therapy.
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Academic Article
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Nuclear epidermal growth factor receptor is a functional molecular target in triple-negative breast cancer.
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Academic Article
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AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma.
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Academic Article
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A new PET/CT volumetric prognostic index for non-small cell lung cancer.
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Academic Article
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Novel EPHB4 Receptor Tyrosine Kinase Mutations and Kinomic Pathway Analysis in Lung Cancer.
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Academic Article
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A randomized phase II study of ganetespib, a heat shock protein 90 inhibitor, in combination with docetaxel in second-line therapy of advanced non-small cell lung cancer (GALAXY-1).
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Academic Article
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Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.
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Academic Article
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Lung cancer-a fractal viewpoint.
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Academic Article
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C. elegans and mutants with chronic nicotine exposure as a novel model of cancer phenotype.
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Academic Article
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Prognostic and Predictive Value in KRAS in Non-Small-Cell Lung Cancer: A Review.
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Academic Article
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FAK and paxillin, two potential targets in pancreatic cancer.
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Academic Article
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Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment.
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Academic Article
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Targeting the HER Family with Pan-HER Effectively Overcomes Resistance to Cetuximab.
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Academic Article
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PI3 Kinase Pathway and MET Inhibition is Efficacious in Malignant Pleural Mesothelioma.
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Academic Article
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Development of response criteria for mesothelioma based on a mathematical model.
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Academic Article
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A randomized phase II study of LY2510924 and carboplatin/etoposide versus carboplatin/etoposide in extensive-disease small cell lung cancer.
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Academic Article
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Prognostic and predictive value of circulating tumor cells and CXCR4 expression as biomarkers for a CXCR4 peptide antagonist in combination with carboplatin-etoposide in small cell lung cancer: exploratory analysis of a phase II study.
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Academic Article
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Differential responsiveness of MET inhibition in non-small-cell lung cancer with altered CBL.
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Academic Article
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Modeling small cell lung cancer (SCLC) biology through deterministic and stochastic mathematical models.
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Academic Article
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2'-Hydroxyflavanone inhibits in vitro and in vivo growth of breast cancer cells by targeting RLIP76.
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Academic Article
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Metastasis of breast tumor cells to brain is suppressed by targeting RLIP alone and in combination with 2'-Hydroxyflavanone.
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Academic Article
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RLIP inhibition suppresses breast-to-lung metastasis.
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Academic Article
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Synergistic efficacy of RLIP inhibition and 2'-hydroxyflavanone against DMBA-induced mammary carcinogenesis in SENCAR mice.
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Academic Article
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Ubiquitin-specific protease 22 is critical to in vivo angiogenesis, growth and metastasis of non-small cell lung cancer.
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Academic Article
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Presence and structure-activity relationship of intrinsically disordered regions across mucins.
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Academic Article
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Precision medicine and actionable alterations in lung cancer: A single institution experience.
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Academic Article
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The promise of selective MET inhibitors in non-small cell lung cancer with MET exon 14 skipping.
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Academic Article
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Targeting RLIP with CRISPR/Cas9 controls tumor growth.
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Academic Article
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AXL Mediates Cetuximab and Radiation Resistance Through Tyrosine 821 and the c-ABL Kinase Pathway in Head and Neck Cancer.
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Academic Article
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Complex Oncological Decision-Making Utilizing Fast-and-Frugal Trees in a Community Setting-Role of Academic and Hybrid Modeling.
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Academic Article
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Inhibitors of the Transcription Factor STAT3 Decrease Growth and Induce Immune Response Genes in Models of Malignant Pleural Mesothelioma (MPM).
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Academic Article
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RLIP depletion induces apoptosis associated with inhibition of JAK2/STAT3 signaling in melanoma cells.
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Academic Article
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Quantifying Cancer: More Than Just a Numbers Game.
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Academic Article
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Essential role of the histone lysine demethylase KDM4A in the biology of malignant pleural mesothelioma (MPM).
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Academic Article
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Dynamic Phenotypic Switching and Group Behavior Help Non-Small Cell Lung Cancer Cells Evade Chemotherapy.
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Academic Article
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Machine learning to refine prognostic and predictive nodal burden thresholds for post-operative radiotherapy in completely resected stage III-N2 non-small cell lung cancer.
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Academic Article
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Utilization of model-agnostic explainable artificial intelligence frameworks in oncology: a narrative review.
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Academic Article
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Prognostic significance of natural products against multidrug tumor resistance.
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Academic Article
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Prognostic Role of Biologically Active Volume of Disease in Patients With Metastatic Lung Adenocarcinoma.
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Grant
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MINIMAL RESIDUAL TUMOR IN SMALL CELL LUNG CANCER
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Grant
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Role of c-Met in SCLC and Potential for Novel Therapy
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Grant
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Studies of a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC)
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Grant
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PAXILLIN--AN ONCOGENE ACTIVATED PROTEIN
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Academic Article
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Recent Advancement in Breast Cancer Research: Insights from Model Organisms-Mouse Models to Zebrafish.
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Academic Article
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Radiation Sensitivity: The Rise of Predictive Patient-Derived Cancer Models.
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