Item Type | Name |
Concept
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Alleles
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Concept
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Amino Acid Sequence
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Concept
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Base Sequence
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Concept
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DNA, Recombinant
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Concept
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Genes, Regulator
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Concept
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Genes, Dominant
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Concept
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Genes
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Concept
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Genes, Bacterial
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Concept
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Multigene Family
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Concept
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Molecular Sequence Data
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Concept
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Repetitive Sequences, Nucleic Acid
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Concept
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Major Histocompatibility Complex
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Concept
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Pseudogenes
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Concept
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Sequence Homology, Nucleic Acid
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Concept
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Genes, ras
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Concept
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Regulatory Sequences, Nucleic Acid
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Concept
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Sequence Tagged Sites
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Concept
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Sequence Homology, Amino Acid
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Concept
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Gene Library
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Concept
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RNA Splice Sites
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Concept
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Genes, Tumor Suppressor
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Concept
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Genes, Wilms Tumor
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Concept
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Genomic Library
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Concept
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Sequence Alignment
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Concept
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Sequence Analysis, DNA
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Concept
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Genes, Reporter
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Concept
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Consensus Sequence
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Concept
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Sequence Deletion
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Concept
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Transgenes
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Concept
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AT Rich Sequence
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Concept
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Exome
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Concept
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Oligonucleotide Array Sequence Analysis
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Concept
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Regulatory Elements, Transcriptional
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Concept
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Genome, Human
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Concept
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Genes, src
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Concept
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Transcriptome
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Concept
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Epistasis, Genetic
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Concept
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Genes, Fungal
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Concept
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Conserved Sequence
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Concept
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Polymorphism, Single Nucleotide
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Concept
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Quantitative Trait Loci
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Concept
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Genetic Loci
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Academic Article
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Sequence and functional characterization of a third inositol trisphosphate receptor subtype, IP3R-3, expressed in pancreatic islets, kidney, gastrointestinal tract, and other tissues.
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Academic Article
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Human glucagon-like peptide-1 receptor gene. Localization to chromosome band 6p21 by fluorescence in situ hybridization and linkage of a highly polymorphic simple tandem repeat DNA polymorphism to other markers on chromosome 6.
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Academic Article
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Cloning and functional comparison of kappa and delta opioid receptors from mouse brain.
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Academic Article
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Hormonal/metabolic regulation of the human GLUT4/muscle-fat facilitative glucose transporter gene in transgenic mice.
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Academic Article
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Candidate gene studies in pedigrees with maturity-onset diabetes of the young not linked with glucokinase.
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Academic Article
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Human insulin receptor substrate-1 gene (IRS1): chromosomal localization to 2q35-q36.1 and identification of a simple tandem repeat DNA polymorphism.
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Academic Article
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cDNA sequence and localization of polymorphic human cytosolic phosphoenolpyruvate carboxykinase gene (PCK1) to chromosome 20, band q13.31: PCK1 is not tightly linked to maturity-onset diabetes of the young.
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Academic Article
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Identification of a simple tandem repeat DNA polymorphism in the human glycogen synthase gene and linkage to five markers on chromosome 19q.
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Academic Article
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Human GLUT4/muscle-fat glucose-transporter gene. Characterization and genetic variation.
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Academic Article
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Linkage and association studies in insulin-dependent diabetes with a new dinucleotide repeat polymorphism at the GAD65 locus.
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Academic Article
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Human hexokinase II gene: exon-intron organization, mutation screening in NIDDM, and its relationship to muscle hexokinase activity.
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Academic Article
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Sequence of human hexokinase III cDNA and assignment of the human hexokinase III gene (HK3) to chromosome band 5q35.2 by fluorescence in situ hybridization.
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Academic Article
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Chromosomal assignment and tissue distribution of novel expressed sequence tags from a human pancreatic islet cDNA library.
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Academic Article
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Characterization of a third simple tandem repeat polymorphism in the human glucokinase gene.
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Academic Article
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Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms.
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Academic Article
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Rat inwardly rectifying potassium channel Kir6.2: cloning electrophysiological characterization, and decreased expression in pancreatic islets of male Zucker diabetic fatty rats.
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Academic Article
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Exclusion of epidermal growth factor and high-resolution physical mapping across the Rieger syndrome locus.
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Academic Article
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Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)
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Academic Article
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Identification of microsatellite markers near the human genes encoding the beta-cell ATP-sensitive K+ channel and linkage studies with NIDDM in Japanese.
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Academic Article
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Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)
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Academic Article
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Detection of a polymorphism within the pepsinogen C gene with PCR: construction of a linkage map around PGC from 6p11-6p21.3.
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Academic Article
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Mutations in the hepatocyte nuclear factor-1alpha gene in MODY and early-onset NIDDM: evidence for a mutational hotspot in exon 4.
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Academic Article
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Searching for NIDDM susceptibility genes: studies of genes with triplet repeats expressed in skeletal muscle.
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Academic Article
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Cloning and characterization of exodus, a novel beta-chemokine.
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Academic Article
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Hepatic function in a family with a nonsense mutation (R154X) in the hepatocyte nuclear factor-4alpha/MODY1 gene.
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Academic Article
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Molecular analysis of the fructose transporter gene (GLUT5) in isolated fructose malabsorption.
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Academic Article
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Increased expression of endothelin B receptor mRNA following subarachnoid hemorrhage in monkeys.
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Academic Article
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Human Oct3 gene family: cDNA sequences, alternative splicing, gene organization, chromosomal location, and expression at low levels in adult tissues.
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Academic Article
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Mutations in the hepatocyte nuclear factor-1alpha/MODY3 gene in Japanese subjects with early- and late-onset NIDDM.
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Academic Article
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Genetic variation in the hepatocyte nuclear factor-1 alpha gene in Danish Caucasians with late-onset NIDDM.
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Academic Article
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An approach for identifying simple sequence repeat DNA polymorphisms near cloned cDNAs and genes. Linkage studies of the islet amyloid polypeptide/amylin and liver glycogen synthase genes and NIDDM.
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Academic Article
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Linkage studies in NIDDM with markers near the sulphonylurea receptor gene.
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Academic Article
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Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus.
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Academic Article
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Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus.
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Academic Article
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Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom.
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Academic Article
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Mutations in the coding region of the neurogenin 3 gene (NEUROG3) are not a common cause of maturity-onset diabetes of the young in Japanese subjects.
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Academic Article
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Abnormal nephron development associated with a frameshift mutation in the transcription factor hepatocyte nuclear factor-1 beta.
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Academic Article
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Linkage analysis of maturity-onset diabetes of the young with microsatellite polymorphisms. No linkage to ADA or GLUT2 genes in two families.
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Academic Article
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Expression and regulation of the human GLUT4/muscle-fat facilitative glucose transporter gene in transgenic mice.
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Academic Article
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A simple test for the high-frequency P291fsinsC mutation in the HNF1 alpha/MODY3 gene.
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Academic Article
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Relationship of insulin receptor substrate-1 and -2 genotypes to phenotypic features of polycystic ovary syndrome.
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Academic Article
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Functional properties of the R154X HNF-4alpha protein generated by a mutation associated with maturity-onset diabetes of the young, type 1.
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Academic Article
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No diabetes-associated mutations in the coding region of the hepatocyte nuclear factor-4gamma gene (HNF4G) in Japanese patients with MODY.
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Academic Article
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Nuclear translocation of SHP and visualization of interaction with HNF-4alpha in living cells.
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Academic Article
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Control of pancreas and liver gene expression by HNF transcription factors.
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Academic Article
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Structure and transcription of the human m3 muscarinic receptor gene.
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Academic Article
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Dual promoter structure of ZFP106: regulation by myogenin and nuclear respiratory factor-1.
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Academic Article
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Anti-diabetic effect of ginsenoside Re in ob/ob mice.
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Academic Article
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Insulin gene mutations as a cause of permanent neonatal diabetes.
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Academic Article
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Association of the (AU)AT-rich element polymorphism in PPP1R3 with hormonal and metabolic features of polycystic ovary syndrome.
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Academic Article
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Characterization of Japanese families with early-onset type 2 (non-insulin dependent) diabetes mellitus and screening for mutations in the glucokinase and mitochondrial tRNA(Leu(UUR)) genes.
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Academic Article
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Identification of microsatellite markers near the human ob gene and linkage studies in NIDDM-affected sib pairs.
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Academic Article
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Identification of two novel amino acid polymorphisms in beta-cell/liver (GLUT2) glucose transporter in Japanese subjects.
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Academic Article
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Splice variant of the somatostatin receptor 2 subtype, somatostatin receptor 2B, couples to adenylyl cyclase.
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Academic Article
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Dinucleotide repeat polymorphism at D9S328E (EST hbc220).
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Academic Article
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Human G-protein-coupled inwardly rectifying potassium channel (GIRK1) gene (KCNJ3): localization to chromosome 2 and identification of a simple tandem repeat polymorphism.
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Academic Article
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Compensation in pancreatic beta-cell function in subjects with glucokinase mutations.
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Academic Article
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Localization of the kappa opioid receptor gene to human chromosome band 8q11.2.
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Academic Article
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Human thyroxine-binding globulin gene: complete sequence and transcriptional regulation.
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Academic Article
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Human hexokinase II: localization of the polymorphic gene to chromosome 2.
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Academic Article
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Assignment of the gastric inhibitory polypeptide receptor gene (GIPR) to chromosome bands 19q13.2-q13.3 by fluorescence in situ hybridization.
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Academic Article
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Human type I pituitary adenylate cyclase activating polypeptide receptor (ADCYAP1R): localization to chromosome band 7p14 and integration into the cytogenetic, physical, and genetic map of chromosome 7.
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Academic Article
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Localization of inositol trisphosphate receptor subtype 3 to insulin and somatostatin secretory granules and regulation of expression in islets and insulinoma cells.
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Academic Article
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Mutation of an aspartate at residue 89 in somatostatin receptor subtype 2 prevents Na+ regulation of agonist binding but does not alter receptor-G protein association.
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Academic Article
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Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency.
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Academic Article
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Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat.
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Academic Article
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A molecular inventory of human pancreatic islets: sequence analysis of 1000 cDNA clones.
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Academic Article
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Localization of the gene encoding a neutral amino acid transporter-like protein to human chromosome band 19q13.3 and characterization of a simple sequence repeat DNA polymorphism.
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Academic Article
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G protein-activated inwardly rectifying potassium channel (GIRK1/KGA) mRNA in adult rat heart and brain by in situ hybridization histochemistry.
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Academic Article
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Mutations in the glucokinase gene are not a major cause of late-onset type 2 (non-insulin-dependent) diabetes mellitus in Japanese subjects.
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Academic Article
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Stimulation of tyrosine phosphatase and inhibition of cell proliferation by somatostatin analogues: mediation by human somatostatin receptor subtypes SSTR1 and SSTR2.
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Academic Article
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Agonists and antagonists bind to different domains of the cloned kappa opioid receptor.
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Academic Article
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Immunological detection of isoforms of the somatostatin receptor subtype, SSTR2.
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Academic Article
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Dinucleotide repeat polymorphism in the NEC2 gene.
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Academic Article
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Expression of calcium channel mRNAs in rat pancreatic islets and downregulation after glucose infusion.
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Academic Article
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Structure and function of ASP, the human homolog of the mouse agouti gene.
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Academic Article
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Linkage of Rieger syndrome to the region of the epidermal growth factor gene on chromosome 4.
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Academic Article
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Assignment of the gene encoding the alpha 1 subunit of the neuroendocrine/brain-type calcium channel (CACNL1A2) to human chromosome 3, band p14.3.
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Academic Article
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Alternative splicing of human inwardly rectifying K+ channel ROMK1 mRNA.
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Academic Article
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Somatostatin receptors, an expanding gene family: cloning and functional characterization of human SSTR3, a protein coupled to adenylyl cyclase.
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Academic Article
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The population association of glucokinase gene with type 2 (noninsulin-dependent) diabetes mellitus in Chinese.
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Academic Article
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Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1.
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Academic Article
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A single residue, aspartic acid 95, in the delta opioid receptor specifies selective high affinity agonist binding.
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Academic Article
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Organization of the human GLUT2 (pancreatic beta-cell and hepatocyte) glucose transporter gene.
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Academic Article
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Differential effects of overexpressed glucokinase and hexokinase I in isolated islets. Evidence for functional segregation of the high and low Km enzymes.
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Academic Article
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A yeast artificial chromosome-based map of the region of chromosome 20 containing the diabetes-susceptibility gene, MODY1, and a myeloid leukemia related gene.
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Academic Article
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Clinical and molecular genetics of neonatal diabetes due to mutations in the insulin gene.
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Academic Article
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Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism.
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Academic Article
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Exome sequencing and genetic testing for MODY.
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Academic Article
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Localization of human homeodomain transcription factor insulin promoter factor 1 (IPF1) to chromosome band 13q12.1.
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Academic Article
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Cloning of rat KATP-2 channel and decreased expression in pancreatic islets of male Zucker diabetic fatty rats.
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Academic Article
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The 31-cM region of chromosome 11 including the obesity gene tubby and ATP-sensitive potassium channel genes, SUR1 and Kir6.2, does not contain a major susceptibility locus for NIDDM in 127 non-Hispanic white affected sibships.
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Academic Article
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Missense glucokinase mutation in maturity-onset diabetes of the young and mutation screening in late-onset diabetes.
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Academic Article
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Cloning of rat and mouse P2Y purinoceptors.
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Academic Article
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Creation of an inositol 1,4,5-trisphosphate-sensitive Ca2+ store in secretory granules of insulin-producing cells.
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Academic Article
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Regulation of expression of the human fructose transporter (GLUT5) by cyclic AMP.
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Academic Article
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Molecular model of human beta-cell glucokinase built by analogy to the crystal structure of yeast hexokinase B.
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Academic Article
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Type 2 (non-insulin-dependent) diabetes mellitus associated with a mutation of the glucokinase gene in a Japanese family.
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Academic Article
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Sequence, tissue distribution, and functional characterization of the rat fructose transporter GLUT5.
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Academic Article
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Cloning of a novel somatostatin receptor, SSTR3, coupled to adenylylcyclase.
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Academic Article
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Dinucleotide repeat polymorphism in the human thyroid hormone receptor alpha gene (THRA1) on chromosome 17.
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Academic Article
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Microsatellite polymorphism in the human platelet glycoprotein IIIa gene (GP3A) on chromosome 17.
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Academic Article
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Human pancreatic beta-cell glucokinase: cDNA sequence and localization of the polymorphic gene to chromosome 7, band p 13.
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Academic Article
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Dinucleotide repeat polymorphism at the human ribophorin II locus (RPN2) on chromosome 20q.
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Academic Article
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Molecular biology of opioid receptors.
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Academic Article
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Localization of the glucagon receptor gene to human chromosome band 17q25.
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Academic Article
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Classification and nomenclature of somatostatin receptors.
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Academic Article
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Inhibition of cell proliferation by the somatostatin analogue RC-160 is mediated by somatostatin receptor subtypes SSTR2 and SSTR5 through different mechanisms.
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Academic Article
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Molecular biology of somatostatin receptors.
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Academic Article
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Characterization of cloned somatostatin receptors SSTR4 and SSTR5.
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Academic Article
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Structure and function of mammalian facilitative sugar transporters.
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Academic Article
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Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides.
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Academic Article
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Molecular biology of somatostatin receptors.
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Academic Article
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Evolution of simple sequence repeats.
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Academic Article
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Gi alpha 1 selectively couples somatostatin receptor subtype 3 to adenylyl cyclase: identification of the functional domains of this alpha subunit necessary for mediating the inhibition by somatostatin of cAMP formation.
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Academic Article
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Altered hepatic gene expression of enzymes involved in energy metabolism in the growth-retarded fetal rat.
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Academic Article
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The length distribution of perfect dimer repetitive DNA is consistent with its evolution by an unbiased single-step mutation process.
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Academic Article
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Identification of gestationally regulated genes in rat myometrium by use of messenger ribonucleic acid differential display.
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Academic Article
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Molecular biology of somatostatin receptors.
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Academic Article
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Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.
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Academic Article
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Association of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population.
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Academic Article
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Continued lessons from the INS gene: an intronic mutation causing diabetes through a novel mechanism.
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Academic Article
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Genome-Wide Association Study of Staphylococcus aureus Carriage in a Community-Based Sample of Mexican-Americans in Starr County, Texas.
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Academic Article
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The genetic architecture of type 2 diabetes.
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Academic Article
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Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees.
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Academic Article
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Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
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Academic Article
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Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
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Academic Article
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Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
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Concept
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Whole Genome Sequencing
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Grant
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GENES RESPONSIBLE IN INSULIN-DEPENDENT DIABETES MELLITUS
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