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One or more keywords matched the following properties of Gurbuxani, Sandeep
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overview As an attending hematopathologist I am involved in diagnostic work up and follow up after therapy of patients diagnosed with hematologic malignancies including AML, ALL, MDS and MDS/MPN. I am interested in understanding the pathogenesis of hematopoietic tumors and how specific events required for leukemic transformation can be targeted for therapy. In addition, as part of collaborative research projects I have been involved in the analyses of mice in models of normal and malignant hematopoiesis.
One or more keywords matched the following items that are connected to Gurbuxani, Sandeep
Item TypeName
Concept Myelodysplastic Syndromes
Academic Article WT1 expression in myelodysplastic syndrome.
Academic Article miR-9 is an essential oncogenic microRNA specifically overexpressed in mixed lineage leukemia-rearranged leukemia.
Academic Article A novel clofarabine bridge strategy facilitates allogeneic transplantation in patients with relapsed/refractory leukemia and high-risk myelodysplastic syndromes.
Academic Article miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia.
Academic Article Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS.
Academic Article Loss of Function of DOCK4 in Myelodysplastic Syndromes Stem Cells is Restored by Inhibitors of DOCK4 Signaling Networks.
Academic Article Lymphoblastic leukemia following MDS or MDS/MPN: clinical evidence for stem cell origins of these disorders.
Academic Article Comparison of myeloid neoplasms with nonclassic 3q26.2/MECOM versus classic inv(3)/t(3;3) rearrangements reveals diverse clinicopathologic features, genetic profiles, and molecular mechanisms of MECOM activation.
Academic Article Therapy-related myeloid neoplasms with normal karyotype show distinct genomic and clinical characteristics compared to their counterparts with abnormal karyotype.
Concept MDS1 and EVI1 Complex Locus Protein
Academic Article The Times, They Are A-Changing: The Impact of Next-Generation Sequencing on Diagnosis, Classification, and Prognostication of Myeloid Malignancies With Focus on Myelodysplastic Syndrome, AML, and Germline Predisposition.
Search Criteria
  • Myelodysplastic syndromes
  • MDS