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Concept
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Mice, Inbred C3H
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Concept
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Mice, Inbred A
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Concept
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Mice, Inbred Strains
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Concept
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Mice, Inbred CBA
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Concept
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Mice, Inbred BALB C
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Concept
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Mice, Inbred C57BL
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Concept
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Mice, Inbred DBA
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Academic Article
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Differential function of intestinal intraepithelial lymphocyte subsets.
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Academic Article
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B7-1 but not B7-2 efficiently costimulates CD8+ T lymphocytes in the P815 tumor system in vitro.
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Academic Article
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Tumor rejection requires a CTLA4 ligand provided by the host or expressed on the tumor: superiority of B7-1 over B7-2 for active tumor immunization.
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Academic Article
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Liver of MRL/lpr mice contain interleukin-4-producing lymphocytes and accessory cells that support the proliferation of Th2 helper T lymphocyte clones.
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Academic Article
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Induction of a cytolytic T-cell response in mice with a recombinant adenovirus coding for tumor antigen P815A.
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Academic Article
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Endogenous IL-12 is necessary for rejection of P815 tumor variants in vivo.
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Academic Article
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Antigen-specific regression of established tumors induced by active immunization with irradiated IL-12- but not B7-1-transfected tumor cells.
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Academic Article
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Antigen recognition and allogeneic tumor rejection in CD8+ TCR transgenic/RAG(-/-) mice.
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Academic Article
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The expression of mouse gene P1A in testis does not prevent safe induction of cytolytic T cells against a P1A-encoded tumor antigen.
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Academic Article
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Interleukin-12-secreting human papillomavirus type 16-transformed cells provide a potent cancer vaccine that generates E7-directed immunity.
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Academic Article
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Cutting edge: differentiation of antitumor CTL in vivo requires host expression of Stat1.
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Academic Article
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Helper T cell differentiation is controlled by the cell cycle.
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Academic Article
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Antigen-specific blockade of T cells in vivo using dimeric MHC peptide.
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Academic Article
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Improved efficacy of dendritic cell vaccines and successful immunization with tumor antigen peptide-pulsed peripheral blood mononuclear cells by coadministration of recombinant murine interleukin-12.
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Academic Article
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Blockade of T cell activation using a surface-linked single-chain antibody to CTLA-4 (CD152).
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Academic Article
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Cutting edge: spontaneous rejection of poorly immunogenic P1.HTR tumors by Stat6-deficient mice.
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Academic Article
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B7DC/PDL2 promotes tumor immunity by a PD-1-independent mechanism.
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Academic Article
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T cell development and function in CrkL-deficient mice.
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Academic Article
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Death of peripheral CD8+ T cells in the absence of MHC class I is Fas-dependent and not blocked by Bcl-xL.
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Academic Article
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Absence of CTLA-4 lowers the activation threshold of primed CD8+ TCR-transgenic T cells: lack of correlation with Src homology domain 2-containing protein tyrosine phosphatase.
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Academic Article
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Epitope spreading upon P815 tumor rejection triggered by vaccination with the single class I MHC-restricted peptide P1A.
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Academic Article
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Absence of programmed death receptor 1 alters thymic development and enhances generation of CD4/CD8 double-negative TCR-transgenic T cells.
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Academic Article
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Evidence implicating utilization of different T cell receptor-associated signaling pathways by TH1 and TH2 clones.
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Academic Article
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Cutting edge: cytotoxic granule polarization and cytolysis can occur without central supramolecular activation cluster formation in CD8+ effector T cells.
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Academic Article
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Homeostatic proliferation plus regulatory T-cell depletion promotes potent rejection of B16 melanoma.
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Academic Article
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Cross-priming of T cells to intracranial tumor antigens elicits an immune response that fails in the effector phase but can be augmented with local immunotherapy.
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Academic Article
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Phenotypic and functional analysis of murine CD3+,CD4-,CD8- TCR-gamma delta-expressing peripheral T cells.
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Academic Article
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Homeostatic proliferation of naïve CD8+ T cells depends on CD62L/L-selectin-mediated homing to peripheral LN.
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Academic Article
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Glucose availability regulates IFN-gamma production and p70S6 kinase activation in CD8+ effector T cells.
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Academic Article
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Evidence implicating I region-restricted antigen presentation in alloantigen and nominal antigen recognition by a dual-reactive helper T lymphocyte clone.
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Academic Article
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Murine hepatic accessory cells support the proliferation of Th1 but not Th2 helper T lymphocyte clones.
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Academic Article
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Costimulation with B7-1, IL-6, and IL-12 is sufficient for primary generation of murine antitumor cytolytic T lymphocytes in vitro.
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Academic Article
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Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones.
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Academic Article
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Differential activation of Th1 and Th2 CD4+ cells by murine brain microvessel endothelial cells and smooth muscle/pericytes.
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Academic Article
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Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells.
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Academic Article
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Induction of the increased Fyn kinase activity in anergic T helper type 1 clones requires calcium and protein synthesis and is sensitive to cyclosporin A.
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Academic Article
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Differential requirement for protein tyrosine kinase Fyn in the functional activation of antigen-specific T lymphocyte clones through the TCR or Thy-1.
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Academic Article
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Anergic T-lymphocyte clones have altered inositol phosphate, calcium, and tyrosine kinase signaling pathways.
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Academic Article
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Targeting the primary tumor to generate CTL for the effective eradication of spontaneous metastases.
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Academic Article
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"Anergy" of TH0 helper T lymphocytes induces downregulation of TH1 characteristics and a transition to a TH2-like phenotype.
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Academic Article
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Beta-catenin inhibits T cell activation by selective interference with linker for activation of T cells-phospholipase C-?1 phosphorylation.
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Academic Article
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Cellular and molecular requirements for rejection of B16 melanoma in the setting of regulatory T cell depletion and homeostatic proliferation.
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Academic Article
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Anti-proliferative effect of IFN-gamma in immune regulation. II. IFN-gamma inhibits the proliferation of murine bone marrow cells stimulated with IL-3, IL-4, or granulocyte-macrophage colony-stimulating factor.
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Academic Article
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Interleukin 2 and concanavalin A stimulate interferon-gamma production in a murine cytolytic T cell clone by different pathways.
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Academic Article
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Expression and function of CTLA-4 in Th1 and Th2 cells.
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Academic Article
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Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells.
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Academic Article
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PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model.
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Academic Article
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Antiproliferative effect of IFN-gamma in immune regulation. III. Differential selection of TH1 and TH2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-gamma.
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Academic Article
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Beta-catenin does not regulate memory T cell phenotype.
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Academic Article
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CD40 ligation reverses T cell tolerance in acute myeloid leukemia.
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Academic Article
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Targeting the tumor microenvironment with interferon-ß bridges innate and adaptive immune responses.
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Academic Article
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Therapeutic activity of high-dose intratumoral IFN-ß requires direct effect on the tumor vasculature.
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Academic Article
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Conditional deletion of PTEN in peripheral T cells augments TCR-mediated activation but does not abrogate CD28 dependency or prevent anergy induction.
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Academic Article
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STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors.
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Academic Article
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STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.
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Academic Article
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Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity.
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Academic Article
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Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy.
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Academic Article
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The composition of the microbiota modulates allograft rejection.
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Academic Article
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NK Cells Restrain Spontaneous Antitumor CD8+ T Cell Priming through PD-1/PD-L1 Interactions with Dendritic Cells.
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Academic Article
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Lymphatic vessels regulate immune microenvironments in human and murine melanoma.
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Academic Article
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The EGR2 targets LAG-3 and 4-1BB describe and regulate dysfunctional antigen-specific CD8+ T cells in the tumor microenvironment.
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Academic Article
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Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity.
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Academic Article
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Tumor heterogeneity and clonal cooperation influence the immune selection of IFN-?-signaling mutant cancer cells.
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