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Gilad, Yoav
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overview The Gilad lab focuses on studying genetic and regulatory differences between humans and our close evolutionary relatives. Our long term goal is to identify the genetic basis of human-specific traits, including genetic variation that underlies higher susceptibility to certain diseases and disorders in humans than in other primates.
One or more keywords matched the following items that are connected to Gilad, Yoav
Item TypeName
Concept Genetic Complementation Test
Concept Models, Genetic
Concept Selection, Genetic
Concept Polymorphism, Genetic
Concept Transcription, Genetic
Concept Transformation, Genetic
Concept Terminator Regions, Genetic
Concept Genetic Variation
Concept Genetic Association Studies
Concept Genetic Speciation
Concept Databases, Genetic
Concept Promoter Regions, Genetic
Concept Epigenomics
Concept Enhancer Elements, Genetic
Concept Genetic Predisposition to Disease
Concept Epigenesis, Genetic
Concept Genetic Loci
Academic Article Sex-specific genetic architecture of human disease.
Academic Article Sex-specific and lineage-specific alternative splicing in primates.
Academic Article Understanding mechanisms underlying human gene expression variation with RNA sequencing.
Academic Article Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data.
Academic Article Noisy splicing drives mRNA isoform diversity in human cells.
Academic Article The effects of EBV transformation on gene expression levels and methylation profiles.
Academic Article Exon-specific QTLs skew the inferred distribution of expression QTLs detected using gene expression array data.
Academic Article Characterizing natural variation using next-generation sequencing technologies.
Academic Article Dissecting the regulatory architecture of gene expression QTLs.
Academic Article The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels.
Academic Article Revealing the architecture of gene regulation: the promise of eQTL studies.
Academic Article The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes.
Academic Article DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines.
Academic Article Comment on "Widespread RNA and DNA sequence differences in the human transcriptome".
Academic Article Comparative studies of gene expression and the evolution of gene regulation.
Academic Article Gene expression differences among primates are associated with changes in a histone epigenetic modification.
Academic Article A genome sequence resource for the aye-aye (Daubentonia madagascariensis), a nocturnal lemur from Madagascar.
Academic Article Comparative RNA sequencing reveals substantial genetic variation in endangered primates.
Academic Article DNase?I sensitivity QTLs are a major determinant of human expression variation.
Academic Article High-resolution mapping of expression-QTLs yields insight into human gene regulation.
Academic Article Gene regulation in primates evolves under tissue-specific selection pressures.
Academic Article Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection.
Academic Article Controls of nucleosome positioning in the human genome.
Academic Article General olfactory sensitivity database (GOSdb): candidate genes and their genomic variations.
Academic Article Comparative studies of gene regulatory mechanisms.
Academic Article The effect of freeze-thaw cycles on gene expression levels in lymphoblastoid cell lines.
Academic Article Social environmental effects on gene regulation.
Academic Article Epigenetic modifications are associated with inter-species gene expression variation in primates.
Academic Article Reprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression Signature.
Academic Article The genetic and mechanistic basis for variation in gene regulation.
Academic Article Genomic variation. Impact of regulatory variation from RNA to protein.
Academic Article Identification of genetic variants that affect histone modifications in human cells.
Academic Article The genetic architecture of gene expression levels in wild baboons.
Academic Article Primate transcript and protein expression levels evolve under compensatory selection pressures.
Academic Article Does a unique olfactory genome imply a unique olfactory world?
Academic Article The functional consequences of variation in transcription factor binding.
Academic Article Host genetic variation influences gene expression response to rhinovirus infection.
Academic Article msCentipede: Modeling Heterogeneity across Genomic Sites and Replicates Improves Accuracy in the Inference of Transcription Factor Binding.
Academic Article Mycobacterial infection induces a specific human innate immune response.
Academic Article Bacterial infection remodels the DNA methylation landscape of human dendritic cells.
Academic Article Genetic Variation, Not Cell Type of Origin, Underlies the Majority of Identifiable Regulatory Differences in iPSCs.
Academic Article RNA splicing is a primary link between genetic variation and disease.
Academic Article Integrated analyses of gene expression and genetic association studies in a founder population.
Academic Article DNA methylation in lung cells is associated with asthma endotypes and genetic risk.
Academic Article Host genetic variation in mucosal immunity pathways influences the upper airway microbiome.
Academic Article Impact of regulatory variation across human iPSCs and differentiated cells.
Academic Article Silencing of transposable elements may not be a major driver of regulatory evolution in primate iPSCs.
Academic Article A Methodological Assessment and Characterization of Genetically-Driven Variation in Three Human Phosphoproteomes.
Academic Article Predicting susceptibility to tuberculosis based on gene expression profiling in dendritic cells.
Academic Article Determining the genetic basis of anthracycline-cardiotoxicity by molecular response QTL mapping in induced cardiomyocytes.
Academic Article Discovery and characterization of variance QTLs in human induced pluripotent stem cells.
Academic Article Dynamic genetic regulation of gene expression during cellular differentiation.
Academic Article A comparison of gene expression and DNA methylation patterns across tissues and species.
Academic Article Prime time for primate functional genomics.
Academic Article Alternative polyadenylation mediates genetic regulation of gene expression.
Academic Article Where Are the Disease-Associated eQTLs?
Academic Article Gene expression variability in human and chimpanzee populations share common determinants.
Academic Article Dynamic effects of genetic variation on gene expression revealed following hypoxic stress in cardiomyocytes.
Academic Article Divergence in alternative polyadenylation contributes to gene regulatory differences between humans and chimpanzees.
Academic Article Functional dynamic genetic effects on gene regulation are specific to particular cell types and environmental conditions.
Academic Article Single-cell sequencing reveals lineage-specific dynamic genetic regulation of gene expression during human cardiomyocyte differentiation.
Grant Analysis and interpretation of noncoding regulatory variation
Grant Mapping eQTLs that affect susceptibility to Tuberculosis
Grant A National iPS Cell Network with Deep Phenotyping for Translational Research
Grant eQTL mapping in iPSC-derived differentiated cardiomyocytes
Grant Mapping QTLs Associated with Variation in RNA Decay Rates
Grant Characterizing and mapping gene regulatory robustness in cardiomyoctes
Grant Characterizing and Understanding Variation in Gene Regulatory Mechanisms Within and Between Species'
Grant The evolution of human specific regulatory pathways
Grant Using single cell RNA-seq to study regulatory noise and robustness
Grant Natural Selection on Gene Regulation in Humans
Grant Genes, genomes, and genotoxicity: in vivo epigenetic toxicology of 1,3-butadiene
Academic Article Genetic regulatory effects in response to a high cholesterol, high fat diet in baboons.
Academic Article Genetic regulatory effects in response to a high-cholesterol, high-fat diet in baboons.
Search Criteria
  • Genetic
  • Epigenetic