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One or more keywords matched the following properties of Karczmar, Gregory
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overview I have developed new approaches to functional and anatomic magnetic resonance imaging for over 30 years. I’ve applied these methods to improve detection and accurate diagnosis of cancer, and monitor cancer response to therapy. I am the Director of Magnetic Resonance Imaging Research at the University of Chicago, and Co-Director of the Advanced Imaging Program of the University of Chicago Comprehensive Cancer center. I’ve collaborated with our outstanding mammographic group and medical physics colleagues for many years to build internationally recognized research program in quantitative breast cancer MR imaging – which parallels and compliments a leading clinical program in breast cancer diagnosis and management. Similarly, I’ve collaborated with Dr. Oto and others to develop a leading translational research program focused on improving prostate cancer screening with MRI, and using MRI to guide therapye. With these collaborators, I’ve made pioneering contributions to MRI methods that improve prostate and breast cancer diagnosis and treatment. My research includes use of pre-clinical methods for breast and prostate cancer to improve understanding of cancer biology and guide the development of improved clinical methods.
One or more keywords matched the following items that are connected to Karczmar, Gregory
Item TypeName
Concept Computer Simulation
Concept Diagnosis, Computer-Assisted
Concept Image Interpretation, Computer-Assisted
Concept Image Processing, Computer-Assisted
Concept Radiographic Image Interpretation, Computer-Assisted
Concept Signal Processing, Computer-Assisted
Concept Diagnosis, Differential
Academic Article Uptake of a superparamagnetic contrast agent imaged by MR with high spectral and spatial resolution.
Academic Article Differentiation of nonmetastatic and metastatic rodent prostate tumors with high spectral and spatial resolution MRI.
Academic Article Imaging spin probe distribution in the tumor of a living mouse with 250 MHz EPR: correlation with BOLD MRI.
Academic Article Breast MR imaging with high spectral and spatial resolutions: preliminary experience.
Academic Article The effect of varying spectral resolution on the quality of high spectral and spatial resolution magnetic resonance images of the breast.
Academic Article Quantitative tumor oxymetric images from 4D electron paramagnetic resonance imaging (EPRI): methodology and comparison with blood oxygen level-dependent (BOLD) MRI.
Academic Article Effects of constant frequency noise in magnetic resonance imaging with nonuniform k-space sampling.
Academic Article Multi-slice DCE-MRI data using P760 distinguishes between metastatic and non-metastatic rodent prostate tumors.
Academic Article High spectral and spatial resolution MRI of breast lesions: preliminary clinical experience.
Academic Article Fat suppression with spectrally selective inversion vs. high spectral and spatial resolution MRI of breast lesions: qualitative and quantitative comparisons.
Academic Article Comparison and evaluation of mouse cardiac MRI acquired with open birdcage, single loop surface and volume birdcage coils.
Academic Article Three-dimensional shear in granular flow.
Academic Article Differentiation between benign and malignant breast lesions detected by bilateral dynamic contrast-enhanced MRI: a sensitivity and specificity study.
Academic Article Multiple reference tissue method for contrast agent arterial input function estimation.
Academic Article Quantitative analysis of water proton spectral lineshape: a novel source of contrast in MRI.
Academic Article A new approach to analysis of the impulse response function (IRF) in dynamic contrast-enhanced MRI (DCEMRI): a simulation study.
Academic Article Anatomical and functional brain imaging using high-resolution echo-planar spectroscopic imaging at 1.5 Tesla.
Academic Article Reproducibility assessment of a multiple reference tissue method for quantitative dynamic contrast enhanced-MRI analysis.
Academic Article Kinetic curves of malignant lesions are not consistent across MRI systems: need for improved standardization of breast dynamic contrast-enhanced MRI acquisition.
Academic Article Comparison of high-resolution echo-planar spectroscopic imaging with conventional MR imaging of prostate tumors in mice.
Academic Article Quantitative analysis of dynamic contrast enhanced MRI for assessment of bowel inflammation in Crohn's disease pilot study.
Academic Article Clinical implementation of a multislice high spectral and spatial resolution-based MRI sequence to achieve unilateral full-breast coverage.
Academic Article Computer simulation of MRS localization techniques: an analysis of ISIS.
Academic Article The influence of temporal resolution in determining pharmacokinetic parameters from DCE-MRI data.
Academic Article Fourier component imaging of water resonance in the human breast provides markers for malignancy.
Academic Article Prostate cancer: differentiation of central gland cancer from benign prostatic hyperplasia by using diffusion-weighted and dynamic contrast-enhanced MR imaging.
Academic Article High-resolution magnetic resonance colonography and dynamic contrast-enhanced magnetic resonance imaging in a murine model of colitis.
Academic Article Abnormalities of the liver evaluated by 31P MRS.
Academic Article Diagnosis of suspicious breast lesions using an empirical mathematical model for dynamic contrast-enhanced MRI.
Academic Article The diverse pathology and kinetics of mass, nonmass, and focus enhancement on MR imaging of the breast.
Academic Article Application of image-guided surface coil P-31 MR spectroscopy to human liver, heart, and kidney.
Academic Article Improvement of the rotating frame experiment by detection of residual Z magnetization: a 31P MRS study of metabolite levels in a Meth-A sarcoma.
Academic Article Magnetic resonance measurement of response to hyperoxia differentiates tumors from normal tissue and may be sensitive to oxygen consumption.
Academic Article Sensitivity to tumor microvasculature without contrast agents in high spectral and spatial resolution MR images.
Academic Article HiSStology: high spectral and spatial resolution magnetic resonance imaging detection of vasculature validated by histology and micro-computed tomography.
Academic Article MR imaging-guided focal laser ablation for prostate cancer: phase I trial.
Academic Article Monitoring anti-angiogenic therapy in colorectal cancer murine model using dynamic contrast-enhanced MRI: comparing pixel-by-pixel with region of interest analysis.
Academic Article High resolution 3D MRI of mouse mammary glands with intra-ductal injection of contrast media.
Academic Article Mammary cancer initiation and progression studied with magnetic resonance imaging.
Academic Article Hybrid multidimensional T(2) and diffusion-weighted MRI for prostate cancer detection.
Academic Article Potential of computer-aided diagnosis of high spectral and spatial resolution (HiSS) MRI in the classification of breast lesions.
Academic Article Comparison of dynamic contrast-enhanced MRI parameters of breast lesions at 1.5 and 3.0?T: a pilot study.
Academic Article High-resolution diffusion-weighted imaging of the prostate.
Academic Article Preliminary assessment of dispersion versus absorption analysis of high spectral and spatial resolution magnetic resonance images in the diagnosis of breast cancer.
Academic Article Short-term reproducibility of apparent diffusion coefficient estimated from diffusion-weighted MRI of the prostate.
Academic Article Arterial input functions (AIFs) measured directly from arteries with low and standard doses of contrast agent, and AIFs derived from reference tissues.
Academic Article B1 and T1 mapping of the breast with a reference tissue method.
Academic Article Ultrafast Bilateral DCE-MRI of the Breast with Conventional Fourier Sampling: Preliminary Evaluation of Semi-quantitative Analysis.
Academic Article Pilot Study of the Use of Hybrid Multidimensional T2-Weighted Imaging-DWI for the Diagnosis of Prostate Cancer and Evaluation of Gleason Score.
Academic Article Kinetic Analysis of Benign and Malignant Breast Lesions With Ultrafast Dynamic Contrast-Enhanced MRI: Comparison With Standard Kinetic Assessment.
Academic Article Fast bilateral breast coverage with high spectral and spatial resolution (HiSS) MRI at 3T.
Academic Article Multiparametric MRI Features and Pathologic Outcome of Wedge-Shaped Lesions in the Peripheral Zone on T2-Weighted Images of the Prostate.
Academic Article Performance of T2 Maps in the Detection of Prostate Cancer.
Academic Article Diagnosis of Prostate Cancer with Noninvasive Estimation of Prostate Tissue Composition by Using Hybrid Multidimensional MR Imaging: A Feasibility Study.
Academic Article Performance of Ultrafast DCE-MRI for Diagnosis of Prostate Cancer.
Academic Article Feasibility of Dynamic Contrast-Enhanced Magnetic Resonance Imaging Using Low-Dose Gadolinium: Comparative Performance With Standard Dose in Prostate Cancer Diagnosis.
Academic Article Ultrafast Dynamic Contrast-Enhanced Breast MRI: Kinetic Curve Assessment Using Empirical Mathematical Model Validated with Histological Microvessel Density.
Academic Article Quantitative analysis of vascular properties derived from ultrafast DCE-MRI to discriminate malignant and benign breast tumors.
Academic Article Comparison of arterial input functions measured from ultra-fast dynamic contrast enhanced MRI and dynamic contrast enhanced computed tomography in prostate cancer patients.
Academic Article Comparison of region-of-interest-averaged and pixel-averaged analysis of DCE-MRI data based on simulations and pre-clinical experiments.
Academic Article Fast Temporal Resolution Dynamic Contrast-Enhanced MRI: Histogram Analysis Versus Visual Analysis for Differentiating Benign and Malignant Breast Lesions.
Academic Article Evaluation of Focal Laser Ablation of Prostate Cancer Using High Spectral and Spatial Resolution Imaging: A Pilot Study.
Academic Article Revisiting quantitative multi-parametric MRI of benign prostatic hyperplasia and its differentiation from transition zone cancer.
Academic Article Diagnosis of Prostate Cancer by Use of MRI-Derived Quantitative Risk Maps: A Feasibility Study.
Academic Article Use of Indicator Dilution Principle to Evaluate Accuracy of Arterial Input Function Measured With Low-Dose Ultrafast Prostate Dynamic Contrast-Enhanced MRI.
Academic Article Discrimination of benign from malignant breast lesions in dense breasts with model-based analysis of regions-of-interest using directional diffusion-weighted images.
Academic Article Signal intensity form of the Tofts model for quantitative analysis of prostate dynamic contrast enhanced MRI data.
Grant MR Virtual Pathology of the Prostate
Academic Article An in silico validation framework for quantitative DCE-MRI techniques based on a dynamic digital phantom.
Academic Article Enhancement-constrained acceleration: A robust reconstruction framework in breast DCE-MRI.
Academic Article Validation of Prostate Tissue Composition by Using Hybrid Multidimensional MRI: Correlation with Histologic Findings.
Academic Article Directional and inter-acquisition variability in diffusion-weighted imaging and editing for restricted diffusion.
Academic Article Safely reducing unnecessary benign breast biopsies by applying non-mass and DWI directional variance filters to ADC thresholding.
Academic Article Parametric maps of spatial two-tissue compartment model for prostate dynamic contrast enhanced MRI - comparison with the standard Tofts model in the diagnosis of prostate cancer.
Grant Assessment of Breast Cancer Risk with High Spectral and Spatial Resolution MRI
Grant High Spectral &Spatial Resolution MRI of Rodent Tumors
Grant Quantitative DCEMRI of Prostate Cancer Correlation with Gold Standards
Academic Article Parametric maps of spatial two-tissue compartment model for prostate dynamic contrast enhanced MRI - comparison with the standard tofts model in the diagnosis of prostate cancer.
Academic Article Four-quadrant vector mapping of hybrid multidimensional MRI data for the diagnosis of prostate cancer.
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  • diagnosis