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Greene, Geoffrey
One or more keywords matched the following items that are connected to
Greene, Geoffrey
Item Type
Name
Concept
Crystallography
Concept
Crystallography, X-Ray
Academic Article
Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism.
Academic Article
Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands.
Academic Article
Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains.
Academic Article
NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses.
Academic Article
Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity.
Academic Article
Structural plasticity in the oestrogen receptor ligand-binding domain.
Academic Article
The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen.
Academic Article
Molecular basis of agonism and antagonism in the oestrogen receptor.
Academic Article
Stapled Peptides with ?-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction.
Academic Article
Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation.
Academic Article
Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer.
Academic Article
Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer.
Search Criteria
Crystallography