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Storb, Ursula

One or more keywords matched the following items that are connected to Storb, Ursula

Item Type	Name
Concept	Mutation
Concept	Point Mutation
Academic Article	The molecular basis of somatic hypermutation of immunoglobulin genes.
Academic Article	The mechanism of somatic hypermutation studied with transgenic and transfected target genes.
Academic Article	Somatic hypermutation of immunoglobulin genes is linked to transcription initiation.
Academic Article	Somatic hypermutation of a lambda 2 transgene under the control of the lambda enhancer or the heavy chain intron enhancer.
Academic Article	Progress in understanding the mechanism and consequences of somatic hypermutation.
Academic Article	B lymphocytes of xeroderma pigmentosum or Cockayne syndrome patients with inherited defects in nucleotide excision repair are fully capable of somatic hypermutation of immunoglobulin genes.
Academic Article	The inactivation of the XP-C gene does not affect somatic hypermutation or class switch recombination of immunoglobulin genes.
Academic Article	Somatic hypermutation of immunoglobulin genes is linked to transcription.
Academic Article	Somatic hypermutation of immunoglobulin and non-immunoglobulin genes.
Academic Article	Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes.
Academic Article	A hypermutable insert in an immunoglobulin transgene contains hotspots of somatic mutation and sequences predicting highly stable structures in the RNA transcript.
Academic Article	The TATA binding protein, c-Myc and survivin genes are not somatically hypermutated, while Ig and BCL6 genes are hypermutated in human memory B cells.
Academic Article	The role of DNA repair in somatic hypermutation of immunoglobulin genes.
Academic Article	Analysis of a T cell receptor gene as a target of the somatic hypermutation mechanism.
Academic Article	A novel cytidine deaminase affects antibody diversity.
Academic Article	A point mutation in the constant region of Ig lambda1 prevents normal B cell development due to defective BCR signaling.
Academic Article	Two conserved essential motifs of the murine immunoglobulin lambda enhancers bind B-cell-specific factors.
Academic Article	A novel cytidine deaminase AIDs in the delivery of error-prone polymerases to immunoglobulin genes.
Academic Article	Mutation pattern of immunoglobulin transgenes is compatible with a model of somatic hypermutation in which targeting of the mutator is linked to the direction of DNA replication.
Academic Article	Scarcity of lambda 1 B cells in mice with a single point mutation in C lambda 1 is due to a low BCR signal caused by misfolded lambda 1 light chain.
Academic Article	Targeting of the activation-induced cytosine deaminase is strongly influenced by the sequence and structure of the targeted DNA.
Academic Article	Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidney.
Academic Article	Alkyladenine DNA glycosylase (Aag) in somatic hypermutation and class switch recombination.
Academic Article	Somatic hypermutation: processivity of the cytosine deaminase AID and error-free repair of the resulting uracils.
Academic Article	Brca1 in immunoglobulin gene conversion and somatic hypermutation.
Academic Article	Somatic hypermutation of an immunoglobulin transgene in kappa transgenic mice.
Academic Article	Analysis of somatic mutations in kappa transgenes.
Academic Article	Somatic mutation of immunoglobulin light-chain variable-region genes.
Academic Article	Expression, allelic exclusion and somatic mutation of mouse immunoglobulin kappa genes.
Academic Article	Attracting AID to targets of somatic hypermutation.
Academic Article	Crossing the SJL lambda locus into kappa-knockout mice reveals a dysfunction of the lambda 1-containing immunoglobulin receptor in B cell differentiation.
Academic Article	Molecular aspects of somatic hypermutation of immunoglobulin genes.
Academic Article	The 3' Igkappa enhancer contains RNA polymerase II promoters: implications for endogenous and transgenic kappa gene expression.
Academic Article	DNA polymerases in immunity: profiting from errors.
Academic Article	The very 5' end and the constant region of Ig genes are spared from somatic mutation because AID does not access these regions.
Academic Article	Why does somatic hypermutation by AID require transcription of its target genes?
Grant	CONTROL OF IMMUNOGLOBULIN SYNTHESIS
Grant	MUTATION OF IG GENES
Grant	Mechanism of Immunoglobulin Hypermutation
Grant	AID in somatic mutation of immunoglobulin genes
Grant	Mechanism of Immunoglobulin Hypermutation
Grant	Immunoglobulin Somatic Mutation
Grant	EXPRESSION OF IMMUNOGLOBULIN GENES

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