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One or more keywords matched the following properties of Drummond, D. Allan
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overview Dr. Drummond is an Associate Professor of Biochemistry & Molecular Biology and Human Genetics. His group studies how cells respond to stress at the molecular level, focusing on formation and dissolution of large assemblies of proteins and RNA during and after stresses such as heat shock. Drummond's lab uses a wide range of techniques, including in vivo imaging, in vitro reconstitution and mechanistic biochemistry, quantitative proteomics, and molecular evolutionary analyses. Because many features of stress-triggered assembly processes are shared across eukaryotes, including humans, the group employs budding yeast, Saccharomyces cerevisiae, as a model organism.
One or more keywords matched the following items that are connected to Drummond, D. Allan
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Concept Saccharomyces cerevisiae Proteins
Concept Saccharomyces cerevisiae
Academic Article Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast.
Academic Article Contact density affects protein evolutionary rate from bacteria to animals.
Academic Article A single determinant dominates the rate of yeast protein evolution.
Academic Article Why highly expressed proteins evolve slowly.
Academic Article Mistranslation-induced protein misfolding as a dominant constraint on coding-sequence evolution.
Academic Article Structural determinants of the rate of protein evolution in yeast.
Academic Article Dying mRNA Tells a Story of Its Life.
Academic Article Reversible, Specific, Active Aggregates of Endogenous Proteins Assemble upon Heat Stress.
Academic Article Stress-Triggered Phase Separation Is an Adaptive, Evolutionarily Tuned Response.
Academic Article Accounting for experimental noise reveals that mRNA levels, amplified by post-transcriptional processes, largely determine steady-state protein levels in yeast.
Academic Article Transient intracellular acidification regulates the core transcriptional heat shock response.
Academic Article Reversible amyloids of pyruvate kinase couple cell metabolism and stress granule disassembly.
Academic Article Chaperones directly and efficiently disperse stress-triggered biomolecular condensates.
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  • Saccharomyces