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CD47 AntigenConcept Why?
"Velcro" engineering of high affinity CD47 ectodomain as signal regulatory protein a (SIRPa) antagonists that enhance antibody-dependent cellular phagocytosis.Academic Article Why?
CD47 blockade triggers T cell-mediated destruction of immunogenic tumors.Academic Article Why?
Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells.Academic Article Why?
Engineered SIRPa variants as immunotherapeutic adjuvants to anticancer antibodies.Academic Article Why?
Intratumoral accumulation of gut microbiota facilitates CD47-based immunotherapy via STING signaling.Academic Article Why?
The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors.Academic Article Why?
Impact of Novel Monoclonal Antibody Therapeutics on Blood Bank Pretransfusion Testing.Academic Article Why?
MYC - a thorn in the side of cancer immunity.Academic Article Why?
Weichselbaum, Ralph R.Person Why?
Ozkan, EnginPerson Why?
Kline, Justin P.Person Why?
Impaired cell adhesion, apoptosis, and signaling in WASP gene-disrupted Nalm-6 pre-B cells and recovery of cell adhesion using a transducible form of WASp.Academic Article Why?
Phase 1 study of anti-CD47 monoclonal antibody CC-90002 in patients with relapsed/refractory acute myeloid leukemia and high-risk myelodysplastic syndromes.Academic Article Why?
Preemptive Tolerogenic Delivery of Donor Antigens for Permanent Allogeneic Islet Graft Protection.Academic Article Why?
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