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Immunodominance and tumor escape.
Academic Article
Why?
A new paradigm for tumor immune escape: ß-catenin-driven immune exclusion.
Academic Article
Why?
Tumor Escape
Concept
Why?
Mechanisms of tumor escape in the context of the T-cell-inflamed and the non-T-cell-inflamed tumor microenvironment.
Academic Article
Why?
Gajewski, Thomas F.
Person
Why?
A tumor escape variant that has lost one major histocompatibility complex class I restriction element induces specific CD8+ T cells to an antigen that no longer serves as a target.
Academic Article
Why?
Elucidating the role of tumor cell-intrinsic hypoxia inducible factor (HIF)-1a and HIF-2a pathway activation in tumor immune evasion
Grant
Why?
Adoptively transferred immune T cells eradicate established tumors despite cancer-induced immune suppression.
Academic Article
Why?
Deficiency of GMDS leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling.
Academic Article
Why?
Identifying and overcoming immune resistance mechanisms in the melanoma tumor microenvironment.
Academic Article
Why?
Impact of oncogenic pathways on evasion of antitumour immune responses.
Academic Article
Why?
Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21.
Academic Article
Why?
Mechanisms of immune evasion by gliomas.
Academic Article
Why?
MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell-Suppressive Functions.
Academic Article
Why?
Molecular mechanism of MART-1+/A*0201+ human melanoma resistance to specific CTL-killing despite functional tumor-CTL interaction.
Academic Article
Why?
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