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E2F Transcription Factors
Concept
Why?
E2F proteins are posttranslationally modified concomitantly with a reduction in nuclear binding activity in cells infected with herpes simplex virus 1.
Academic Article
Why?
Du, Wei
Person
Why?
BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy.
Academic Article
Why?
Rb family-independent activating E2F increases genome stability, promotes homologous recombination, and decreases non-homologous end joining.
Academic Article
Why?
Cell cycle regulation.
Academic Article
Why?
Critical role of active repression by E2F and Rb proteins in endoreplication during Drosophila development.
Academic Article
Why?
E2F is required to prevent inappropriate S-phase entry of mammalian cells.
Academic Article
Why?
Endocycle and E2F-dependent transcriptional activation and repression.
Academic Article
Why?
RB deletion disrupts coordination between DNA replication licensing and mitotic entry in vivo.
Academic Article
Why?
Macleod, Kay
Person
Why?
Ectopic expression of dE2F and dDP induces cell proliferation and death in the Drosophila eye.
Academic Article
Why?
Regulation of apoptosis of rbf mutant cells during Drosophila development.
Academic Article
Why?
Requirements for dE2F function in proliferating cells and in post-mitotic differentiating cells.
Academic Article
Why?
An integrated view of cyclin E function and regulation.
Academic Article
Why?
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