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Pearson, Alexander
One or more keywords matched the following properties of Pearson, Alexander
PropertyValue
keywords Statistical Models
keywords Mathematical Model
keywords Neural Network Models
keywords Models, Biologic
overview The Pearson Lab integrates clinical expertise, mathematical modeling, high dimensional statistics, and basic tumor biology methods to investigate and propose new treatments for head and neck cancer.
One or more keywords matched the following items that are connected to Pearson, Alexander
Item TypeName
Concept Models, Theoretical
Concept Proportional Hazards Models
Concept Models, Animal
Concept Logistic Models
Concept Xenograft Model Antitumor Assays
Concept Disease Models, Animal
Concept Models, Biological
Academic Article Capecitabine after Surgical Salvage in Recurrent Squamous Cell Carcinoma of Head and Neck.
Academic Article Therapeutic Inhibition of the MDM2-p53 Interaction Prevents Recurrence of Adenoid Cystic Carcinomas.
Academic Article 5T4-Targeted Therapy Ablates Cancer Stem Cells and Prevents Recurrence of Head and Neck Squamous Cell Carcinoma.
Academic Article A mathematical model for IL-6-mediated, stem cell driven tumor growth and targeted treatment.
Academic Article Anti-tumor effect of inhibition of IL-6 signaling in mucoepidermoid carcinoma.
Academic Article Modeling head and neck cancer stem cell-mediated tumorigenesis.
Academic Article Patient-derived xenograft (PDX) tumors increase growth rate with time.
Academic Article UM-HACC-2A: MYB-NFIB fusion-positive human adenoid cystic carcinoma cell line.
Academic Article Ablation of Cancer Stem Cells by Therapeutic Inhibition of the MDM2-p53 Interaction in Mucoepidermoid Carcinoma.
Academic Article The Endothelin-A Receptor Antagonist Zibotentan Induces Damage to the Nasal Olfactory Epithelium Possibly Mediated in Part through Type 2 Innate Lymphoid Cells.
Academic Article In Silico Models Accurately Predict In Vivo Response for IL6 Blockade in Head and Neck Cancer.
Academic Article Identifying predictors of HPV-related head and neck squamous cell carcinoma progression and survival through patient-derived models.
Academic Article Machine Learning-Guided Adjuvant Treatment of Head and Neck Cancer.
Academic Article Wnt-ß-catenin activation epigenetically reprograms Treg cells in inflammatory bowel disease and dysplastic progression.
Academic Article The impact of site-specific digital histology signatures on deep learning model accuracy and bias.
Academic Article The IL-6R and Bmi-1 axis controls self-renewal and chemoresistance of head and neck cancer stem cells.
Academic Article A validated mathematical model of FGFR3-mediated tumor growth reveals pathways to harness the benefits of combination targeted therapy and immunotherapy in bladder cancer.
Academic Article Classical mathematical models for prediction of response to chemotherapy and immunotherapy.
Academic Article Development and Validation of a Decision Analytical Model for Posttreatment Surveillance for Patients With Oropharyngeal Carcinoma.
Academic Article A global method for fast simulations of molecular dynamics in multiscale agent-based models of biological tissues.
Academic Article A nanoengineered topical transmucosal cisplatin delivery system induces anti-tumor response in animal models and patients with oral cancer.
Academic Article Uncertainty-informed deep learning models enable high-confidence predictions for digital histopathology.
Academic Article Author Correction: A nanoengineered topical transmucosal cisplatin delivery system induces anti-tumor response in animal models and patients with oral cancer.
Concept Patient-Specific Modeling
Grant Deep learning for oral premalignancy evaluation
Academic Article Single-Cell Dynamics Determines Response to CDK4/6 Inhibition in Triple-Negative Breast Cancer.
Academic Article ATR Inhibition Potentiates the Radiation-induced Inflammatory Tumor Microenvironment.
Academic Article FGFR signaling promotes the growth of triple-negative and basal-like breast cancer cell lines both in vitro and in vivo.
Academic Article Deep learning-based subtyping of gastric cancer histology predicts clinical outcome: a multi-institutional retrospective study.
Academic Article Mathematical model predicts tumor control patterns induced by fast and slow cytotoxic T lymphocyte killing mechanisms.
Academic Article External Evaluation of a Mammography-based Deep Learning Model for Predicting Breast Cancer in an Ethnically Diverse Population.
Academic Article Dysregulated FGFR3 signaling alters the immune landscape in bladder cancer and presents therapeutic possibilities in an agent-based model.
Academic Article Using histopathology latent diffusion models as privacy-preserving dataset augmenters improves downstream classification performance.
Academic Article Evaluation of large language models as a diagnostic aid for complex medical cases.
Academic Article Agent-Based Modeling of Virtual Tumors Reveals the Critical Influence of Microenvironmental Complexity on Immunotherapy Efficacy.
Academic Article Counterfactual Diffusion Models for Mechanistic Explainability of Artificial Intelligence Models in Pathology.
Academic Article PRMT5 inhibition has a potent anti-tumor activity against adenoid cystic carcinoma of salivary glands.
Academic Article End-to-end prediction of clinical outcomes in head and neck squamous cell carcinoma with foundation model-based multiple instance learning.
Academic Article Analysis of AI foundation model features decodes the histopathologic landscape of HPV-positive head and neck squamous cell carcinomas.
Search Criteria
  • Modeling