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Search Results to David Pincus

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overview David Pincus is an Assistant Professor in the Dept. of Molecular Genetics and Cell Biology. The Pincus lab is located in the Center for Physics of Evolving Systems on the 5th floor of GCIS. The Pincus Lab studies "System Mechanics of Cellular Stress Responses", defined as quantitative control processes cells employ to sense and respond to environmental and endogenous perturbations. David is trained in approaches in biochemistry, biophysics, genetics, and molecular, cell, computational, systems and synthetic biology. The lab uses budding yeast and cultured human cells as experimental models, and applies this toolkit to investigate three interconnected areas: 1) Hsf1, chaperones, and proteostasis networks 2) Stress responsive kinase signaling 3) Stress responsive gene expression The goal of the research program is to understand the establishment and maintenance of cell-level homeostasis.

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