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Al-Hendy, Ayman
One or more keywords matched the following items that are connected to Al-Hendy, Ayman
Item TypeName
Concept Leiomyoma
Academic Article Role of vitamin D in uterine fibroid biology.
Academic Article Vitamin D3 Inhibits Wnt/ß-Catenin and mTOR Signaling Pathways in Human Uterine Fibroid Cells.
Academic Article Vitamin D and uterine fibroids: preclinical evidence is in; time for an overdue clinical study!
Academic Article Can vitamin D reduce the risk of uterine fibroids?
Academic Article Serum vitamin D3 level inversely correlates with uterine fibroid volume in different ethnic groups: a cross-sectional observational study.
Academic Article Elagolix Treatment for Up to 12 Months in Women With Heavy Menstrual Bleeding and Uterine Leiomyomas.
Academic Article Towards non-surgical therapy for uterine fibroids: catechol-O-methyl transferase inhibitor shrinks uterine fibroid lesions in the Eker rat model.
Academic Article Gene therapy and uterine leiomyoma: a review.
Academic Article The Polycomb Group Protein EZH2 Impairs DNA Damage Repair Gene Expression in Human Uterine Fibroids.
Academic Article Uterine Fibroids: Burden and Unmet Medical Need.
Academic Article Expanding upon the Human Myometrial Stem Cell Hypothesis and the Role of Race, Hormones, Age, and Parity in a Profibroid Environment.
Academic Article Adenovirus-mediated delivery of a dominant-negative estrogen receptor gene in uterine leiomyoma cells abrogates estrogen- and progesterone-regulated gene expression.
Academic Article Berberine Inhibits Uterine Leiomyoma Cell Proliferation via Downregulation of Cyclooxygenase 2 and Pituitary Tumor-Transforming Gene 1.
Academic Article Adipocytes enhance the proliferation of human leiomyoma cells via TNF-a proinflammatory cytokine.
Academic Article 1,25-dihydroxyvitamin D3 regulates expression of sex steroid receptors in human uterine fibroid cells.
Academic Article Racial and ethnic differences in the pathogenesis and clinical manifestations of uterine leiomyoma.
Academic Article Identification of Polycomb Group Protein EZH2-Mediated DNA Mismatch Repair Gene MSH2 in Human Uterine Fibroids.
Academic Article Elagolix Alone or With Add-Back Therapy in Women With Heavy Menstrual Bleeding and Uterine Leiomyomas: A Randomized Controlled Trial.
Academic Article Ethnic distribution of estrogen receptor-alpha polymorphism is associated with a higher prevalence of uterine leiomyomas in black Americans.
Academic Article Elagolix for Heavy Menstrual Bleeding in Women with Uterine Fibroids.
Academic Article Uterine fibroids in menopause and perimenopause.
Academic Article Defective expression of ATG4D abrogates autophagy and promotes growth in human uterine fibroids.
Academic Article Silencing Med12 Gene Reduces Proliferation of Human Leiomyoma Cells Mediated via Wnt/ß-Catenin Signaling Pathway.
Academic Article Uterine fibroids are characterized by an impaired antioxidant cellular system: potential role of hypoxia in the pathophysiology of uterine fibroids.
Academic Article Memy I: a novel murine model for uterine leiomyoma using adenovirus-enhanced human fibroid explants in severe combined immune deficiency mice.
Academic Article Nicotinamide adenine dinucleotide phosphate oxidase is differentially regulated in normal myometrium versus leiomyoma.
Academic Article Stro-1/CD44 as putative human myometrial and fibroid stem cell markers.
Academic Article Myometrial progesterone hyper-responsiveness associated with increased risk of human uterine fibroids.
Academic Article Selective progesterone receptor modulators for fertility preservation in women with symptomatic uterine fibroids.
Academic Article The Selective Progesterone Receptor Modulator Ulipristal Acetate Inhibits the Activity of the Glucocorticoid Receptor.
Academic Article Molecular genetics and racial disparities of uterine leiomyomas.
Academic Article Early Life Adverse Environmental Exposures Increase the Risk of Uterine Fibroid Development: Role of Epigenetic Regulation.
Academic Article Converting of Myometrial Stem Cells to Tumor-Initiating Cells: Mechanism of Uterine Fibroid Development.
Academic Article Antiproliferative and proapoptotic effects of epigallocatechin gallate on human leiomyoma cells.
Academic Article 1,25-dihydroxyvitamin D3 treatment shrinks uterine leiomyoma tumors in the Eker rat model.
Academic Article Gene therapy of benign gynecological diseases.
Academic Article Estrogen metabolite 2-methoxyestradiol induces apoptosis and inhibits cell proliferation and collagen production in rat and human leiomyoma cells: a potential medicinal treatment for uterine fibroids.
Academic Article Mediator Kinase Disruption in MED12-Mutant Uterine Fibroids From Hispanic Women of South Texas.
Academic Article A Preliminary Study: Human Fibroid Stro-1+/CD44+ Stem Cells Isolated From Uterine Fibroids Demonstrate Decreased DNA Repair and Genomic Integrity Compared to Adjacent Myometrial Stro-1+/CD44+ Cells.
Academic Article The Evolving Role of Natural Compounds in the Medical Treatment of Uterine Fibroids.
Academic Article Vitamin D, a promising natural compound with anti-uterine fibroid characteristics.
Academic Article 1,25-dihydroxyvitamin d3 reduces extracellular matrix-associated protein expression in human uterine fibroid cells.
Academic Article Burden, Prevalence, and Treatment of Uterine Fibroids: A Survey of U.S. Women.
Academic Article Molecular Bio-Imaging Probe for Non-Invasive Differentiation Between Human Leiomyoma Versus Leiomyosarcoma.
Academic Article Gene therapy of uterine leiomyomas: adenovirus-mediated expression of dominant negative estrogen receptor inhibits tumor growth in nude mice.
Academic Article Oxidative stress: a key regulator of leiomyoma cell survival.
Academic Article Vitamin D3 inhibits expression and activities of matrix metalloproteinase-2 and -9 in human uterine fibroid cells.
Academic Article Introduction of Somatic Mutation in MED12 Induces Wnt4/ß-Catenin and Disrupts Autophagy in Human Uterine Myometrial Cell.
Academic Article Signaling Pathways in Leiomyoma: Understanding Pathobiology and Implications for Therapy.
Academic Article Successes and failures of uterine leiomyoma drug discovery.
Academic Article Simvastatin and uterine fibroids: opportunity for a novel therapeutic option.
Academic Article 1,25 Dihydroxyvitamin D3 Enhances the Antifibroid Effects of Ulipristal Acetate in Human Uterine Fibroids.
Academic Article Targeted Adenoviral Vector Demonstrates Enhanced Efficacy for In Vivo Gene Therapy of Uterine Leiomyoma.
Academic Article Uterine Leiomyoma: New Perspectives on an Old Disease.
Academic Article Origin of Uterine Fibroids: Conversion of Myometrial Stem Cells to Tumor-Initiating Cells.
Academic Article Uterine Fibroids: Bridging Genomic Defects and Chronic Inflammation.
Academic Article Novel MED12 gene somatic mutations in women from the Southern United States with symptomatic uterine fibroids.
Academic Article Hypovitaminosis D and high serum transforming growth factor beta-3: important biomarkers for uterine fibroids risk.
Academic Article Vitamin D3 Ameliorates DNA Damage Caused by Developmental Exposure to Endocrine Disruptors in the Uterine Myometrial Stem Cells of Eker Rats.
Academic Article Treatment of symptomatic uterine fibroids with green tea extract: a pilot randomized controlled clinical study.
Academic Article Potential nonhormonal therapeutics for medical treatment of leiomyomas.
Academic Article Simvastatin potently induces calcium-dependent apoptosis of human leiomyoma cells.
Academic Article Toward gene therapy of uterine fibroids: targeting modified adenovirus to human leiomyoma cells.
Academic Article Neurotrimin: a novel neural cell adhesion molecule correlating with uterine fibroid phenotype.
Academic Article Innovative oral treatments of uterine leiomyoma.
Academic Article Berberine inhibits the proliferation of human uterine leiomyoma cells.
Academic Article Hormonal regulation of catechol-O-methyl transferase activity in women with uterine leiomyomas.
Academic Article Vitamin D inhibits proliferation of human uterine leiomyoma cells via catechol-O-methyltransferase.
Academic Article Predictors of response for elagolix with add-back therapy in women with heavy menstrual bleeding associated with uterine fibroids.
Academic Article Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19.
Academic Article Activation of ß-Catenin Signaling and its Crosstalk With Estrogen and Histone Deacetylases in Human Uterine Fibroids.
Academic Article Novel effects of simvastatin on uterine fibroid tumors: in vitro and patient-derived xenograft mouse model study.
Academic Article Alcohol Consumption and Risk of Uterine Fibroids.
Academic Article Non-coding RNAs: an important regulatory mechanism in pathogenesis of uterine fibroids.
Academic Article Endocrine disruptor exposure during development increases incidence of uterine fibroids by altering DNA repair in myometrial stem cells.
Academic Article Green tea extract inhibits proliferation of uterine leiomyoma cells in vitro and in nude mice.
Academic Article Targeting the transforming growth factor-ß pathway: a novel mechanism of ulipristal acetate action against uterine fibroids.
Academic Article Catechol-O-methyltransferase polymorphism is associated with increased uterine leiomyoma risk in different ethnic groups.
Academic Article 1,25-Dihydroxyvitamin D3 reduces TGF-beta3-induced fibrosis-related gene expression in human uterine leiomyoma cells.
Academic Article Paricalcitol, a vitamin d receptor activator, inhibits tumor formation in a murine model of uterine fibroids.
Academic Article Green tea extract inhibition of human leiomyoma cell proliferation is mediated via catechol-O-methyltransferase.
Academic Article Medical treatment of uterine leiomyoma.
Academic Article Identification and potential role of telocytes in human uterine leiomyoma.
Academic Article Gene therapy targeting leiomyoma: adenovirus-mediated delivery of dominant-negative estrogen receptor gene shrinks uterine tumors in Eker rat model.
Academic Article Targeting adenoviral vectors for enhanced gene therapy of uterine leiomyomas.
Academic Article Estrogen Receptors and Signaling in Fibroids: Role in Pathobiology and Therapeutic Implications.
Academic Article Evolving role of microRNAs in uterine fibroid pathogenesis: filling the gap!
Academic Article Gene therapy of uterine leiomyoma: adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir treatment inhibits growth of human and rat leiomyoma cells in vitro and in a nude mouse model.
Academic Article Magnetic nanoparticles as a new approach to improve the efficacy of gene therapy against differentiated human uterine fibroid cells and tumor-initiating stem cells.
Academic Article Burden of Uterine Fibroids: An African Perspective, A Call for Action and Opportunity for Intervention.
Academic Article Hypovitaminosis D exacerbates the DNA damage load in human uterine fibroids, which is ameliorated by vitamin D3 treatment.
Academic Article Endocrine-disrupting chemicals and uterine fibroids.
Academic Article Ulipristal Acetate for Treatment of Symptomatic Uterine Leiomyomas: A Randomized Controlled Trial.
Academic Article Uterine fibroid therapy: the pharmacokinetic considerations.
Academic Article The Mechanism and Function of Epigenetics in Uterine Leiomyoma Development.
Academic Article H19 lncRNA identified as a master regulator of genes that drive uterine leiomyomas.
Academic Article Towards fibroid gene therapy: adenovirus-mediated delivery of herpes simplex virus 1 thymidine kinase gene/ganciclovir shrinks uterine leiomyoma in the Eker rat model.
Academic Article Developmental Exposure to Endocrine Disruptors Expands Murine Myometrial Stem Cell Compartment as a Prerequisite to Leiomyoma Tumorigenesis.
Academic Article Vitamins and Uterine Fibroids: Current Data on Pathophysiology and Possible Clinical Relevance.
Academic Article Non-hormonal mediators of uterine fibroid growth.
Academic Article The role of endocrine-disrupting chemicals in uterine fibroid pathogenesis.
Academic Article The Significance of Measuring Vitamin D Serum Levels in Women with Uterine Fibroids.
Academic Article Targeting Hedgehog Pathway and DNA Methyltransferases in Uterine Leiomyosarcoma Cells.
Academic Article Treatment of Uterine Fibroid Symptoms with Relugolix Combination Therapy.
Academic Article Proteogenomic landscape of uterine leiomyomas from hereditary leiomyomatosis and renal cell cancer patients.
Academic Article Understanding the Impact of Uterine Fibroids on Human Endometrium Function.
Academic Article Summary of the Proceedings of the Basic Science of Uterine Fibroids Meeting: New Developments February 28, 2020.
Academic Article Simvastatin modulates estrogen signaling in uterine leiomyoma via regulating receptor palmitoylation, trafficking and degradation.
Academic Article Reduction of Heavy Menstrual Bleeding in Women Not Designated as Responders to Elagolix Plus Add Back Therapy for Uterine Fibroids.
Academic Article Current approaches to overcome the side effects of GnRH analogs in the treatment of patients with uterine fibroids.
Academic Article Endocrine-Disrupting Chemicals and Vitamin D Deficiency in the Pathogenesis of Uterine Fibroids.
Academic Article Comprehensive Review of Uterine Fibroids: Developmental Origin, Pathogenesis, and Treatment.
Academic Article An evaluation of relugolix/estradiol/norethindrone acetate for the treatment of heavy menstrual bleeding associated with uterine fibroids in premenopausal women.
Academic Article Simvastatin inhibits stem cell proliferation in human leiomyoma via TGF-ß3 and Wnt/ß-Catenin pathways.
Academic Article A Call-to-Action for Clinicians to Implement Evidence-Based Best Practices When Caring for Women with Uterine Fibroids.
Academic Article Epigenetic Regulation in Uterine Fibroids-The Role of Ten-Eleven Translocation Enzymes and Their Potential Therapeutic Application.
Academic Article Adverse childhood experiences and health-related quality of life among women undergoing hysterectomy for uterine leiomyoma.
Academic Article Human Myometrial and Uterine Fibroid Stem Cell-Derived Organoids for Intervening the Pathophysiology of Uterine Fibroid.
Academic Article Report of Exosomes Isolated from a Human Uterine Leiomyoma Cell Line and Their Impact on Endometrial Vascular Endothelial Cells.
Academic Article Relugolix Combination Therapy for Uterine Leiomyoma-Associated Pain in the LIBERTY Randomized Trials.
Academic Article The Functional Role and Regulatory Mechanism of Bromodomain-Containing Protein 9 in Human Uterine Leiomyosarcoma.
Academic Article Assessing the Hepatic Safety of Epigallocatechin Gallate (EGCG) in Reproductive-Aged Women.
Academic Article Uterine fibroids - Causes, impact, treatment, and lens to the African perspective.
Academic Article Linzagolix with and without hormonal add-back therapy for the treatment of symptomatic uterine fibroids: two randomised, placebo-controlled, phase 3 trials.
Academic Article Long-term Relugolix Combination Therapy for Symptomatic Uterine Leiomyomas.
Academic Article Quality of life with relugolix combination therapy for uterine fibroids: LIBERTY randomized trials.
Academic Article Gene Expression Profile of Uterine Leiomyoma from Women Exposed to Different Air Pollution Levels in Metropolitan Cities of Sao Paulo, Brazil.
Grant Targeting Adenovirus for Gene Therapy of Uterine Leiomyoma
Grant Gene X Environment Interactions in the Pathogenesis of Uterine Fibroids
Grant Hypovitaminosis D promotes MED12-associated genomic instability in uterine fibroids
Grant Pathological reprogramming of the m6A epitranscriptome in uterine fibroids
Grant 3/4, University of Illinois at Chicago Clinical Site- Reproductive Medicine Collaborative Consortium: A randomized placebo-controlled trial of EGCG to improve fertility in women with uterine fibroids
Academic Article A plain language summary of the safety of relugolix combination therapy and improvement in symptoms in women with uterine fibroids from the LIBERTY 1 and LIBERTY 2 studies.
Academic Article Update on the Role and Regulatory Mechanism of Extracellular Matrix in the Pathogenesis of Uterine Fibroids.
Academic Article EZH2 activates Wnt/ß-catenin signaling in human uterine fibroids, which is inhibited by the natural compound methyl jasmonate.
Academic Article Progesterone Signaling and Uterine Fibroid Pathogenesis; Molecular Mechanisms and Potential Therapeutics.
Academic Article GnRH analogs for the treatment of heavy menstrual bleeding associated with uterine fibroids.
Academic Article Efficacy and safety of vilaprisan in women with uterine fibroids: data from the ASTEROID 3 randomized controlled trial.
Academic Article A plain language summary of the long-term relugolix combination therapy study for uterine fibroids.
Academic Article Epigenetic Modulation of Inflammatory Pathways in Myometrial Stem Cells and Risk of Uterine Fibroids.
Academic Article Prevention of Uterine Fibroids: molecular mechanisms and potential clinical application.
Academic Article TGFß signaling links early life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells.
Academic Article Uterine Fibroids: A Podcast on Patient and Physician Perspectives on Medical Management and a New Medical Therapy (Relugolix Combination Therapy).
Academic Article GnRH agonists and antagonists in therapy of symptomatic uterine fibroids - current roles and future perspectives.
Academic Article Developmental reprogramming of myometrial stem cells by endocrine disruptor linking to risk of uterine fibroids.
Academic Article LIBERTY randomized withdrawal study: relugolix combination therapy for heavy menstrual bleeding associated with uterine fibroids.
Academic Article The combination of natural compounds Crila and epigallocatechin gallate showed enhanced antiproliferative effects on human uterine fibroid cells compared with single treatments.
Academic Article Relugolix combination therapy in Black/African American women with symptomatic uterine fibroids: LIBERTY Long-Term Extension study.
Academic Article Current and Emerging Treatment Options for Uterine Fibroids.
Academic Article Evidence-Based Approach for Secondary Prevention of Uterine Fibroids (The ESCAPE Approach).
Academic Article Survivin-Sodium Iodide Symporter Reporter as a Non-Invasive Diagnostic Marker to Differentiate Uterine Leiomyosarcoma from Leiomyoma.
Academic Article Endocrine-disrupting chemicals and epigenetic reprogramming in developmental origin of uterine fibroids.
Academic Article Fibroids and unexplained infertility treatment with epigallocatechin gallate: a natural compound in green tea (FRIEND) - protocol for a randomised placebo-controlled US multicentre clinical trial of EGCG to improve fertility in women with uterine fibroids.
Academic Article Bromodomain-Containing Protein 9 Regulates Signaling Pathways and Reprograms the Epigenome in Immortalized Human Uterine Fibroid Cells.
Academic Article Management of Uterine Fibroids and Sarcomas: The Palermo Position Paper.
Academic Article Epigallocatechin Gallate for the Treatment of Benign and Malignant Gynecological Diseases-Focus on Epigenetic Mechanisms.
Academic Article Empowering Strategies for Lifestyle Interventions, Diet Modifications, and Environmental Practices for Uterine Fibroid Prevention; Unveiling the LIFE UP Awareness.
Academic Article Quality of life improvements in women with uterine fibroids treated with relugolix combination therapy during the LIBERTY long-term extension study: A descriptive subgroup analysis in women with anemia at baseline.
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