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One or more keywords matched the following properties of Mukherjee, Sampriti
keywords Bacterial genetics
keywords Bacterial sensory signal transduction
overview Our overarching goal is to understand how bacteria decode and integrate self-generated and environmentally-derived stimuli to control transitions between individual and collective behaviors. Bacterial responses to self-generated and exogenous stimuli influence their survival, persistence in particular niches, and lifestyle transitions, such as alterations between being free-swimming (individual behavior) or existing in structured antibiotic-resistant communities called biofilms (collective behavior). How the information encoded in multiple sensory inputs is extracted and integrated to drive transitions between individual and collective behaviors is largely mysterious. We use bacterial genetics, molecular biology, biochemistry, microfluidics, fluorescence microscopy, and genome-scale studies to study fundamental questions about bacterial signal detection, signal relay, signal integration, and the consequences to collective behaviors. Ultimately, understanding how information encoded in diverse sensory inputs drives collective behaviors will be foundational for designing successful synthetic strategies to enhance or to inhibit biofilms and for developing novel therapeutic interventions.
One or more keywords matched the following items that are connected to Mukherjee, Sampriti
Item TypeName
Concept Bacterial Adhesion
Concept Bacterial Proteins
Concept RNA, Bacterial
Concept Bacterial Secretion Systems
Concept Anti-Bacterial Agents
Concept Signal Transduction
Concept Gene Expression Regulation, Bacterial
Concept Bacterial Physiological Phenomena
Academic Article Bacterial quorum sensing in complex and dynamically changing environments.
Academic Article Bacterial Biofilm Material Properties Enable Removal and Transfer by Capillary Peeling.
Academic Article Adaptor-mediated Lon proteolysis restricts Bacillus subtilis hyperflagellation.
Academic Article CsrA-FliW interaction governs flagellin homeostasis and a checkpoint on flagellar morphogenesis in Bacillus subtilis.
Academic Article Photosensing and quorum sensing are integrated to control Pseudomonas aeruginosa collective behaviors.
Academic Article The RhlR quorum-sensing receptor controls Pseudomonas aeruginosa pathogenesis and biofilm development independently of its canonical homoserine lactone autoinducer.
Academic Article Flavonoids Suppress Pseudomonas aeruginosa Virulence through Allosteric Inhibition of Quorum-sensing Receptors.
Academic Article FliW antagonizes CsrA RNA binding by a noncompetitive allosteric mechanism.
Academic Article csrT Represents a New Class of csrA-Like Regulatory Genes Associated with Integrative Conjugative Elements of Legionella pneumophila.
Academic Article The canonical twin-arginine translocase components are not required for secretion of folded green fluorescent protein from the ancestral strain of Bacillus subtilis.
Academic Article Functional characterization of core components of the Bacillus subtilis cyclic-di-GMP signaling pathway.
Academic Article FliW and FliS function independently to control cytoplasmic flagellin levels in Bacillus subtilis.
Academic Article Bacterial Biofilm Material Properties Enable Removal and Transfer by Capillary Peeling.
Academic Article The PqsE and RhlR proteins are an autoinducer synthase-receptor pair that control virulence and biofilm development in Pseudomonas aeruginosa.
Academic Article FliS/flagellin/FliW heterotrimer couples type III secretion and flagellin homeostasis.
Academic Article The structure and regulation of flagella in Bacillus subtilis.
Academic Article Another battle won in the phage-host arms race: Pseudomonas phage blocks quorum sensing regulator LasR.
Grant A new quorum-sensing autoinducer acts with the RhlR receptor to control virulence and biofilms in Pseudomonas aeruginosa
Grant A New Quorum-Sensing Autoinducer Acts with the RhlR Receptor to Control Virulence and Biofilms in Pseudomonas Aeruginosa
Grant Probing the role of sensory cues in the regulation of bacterial biofilm development
Search Criteria
  • Bacterial
  • sensory
  • signal transduction