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Search Results to Gokhan M. Mutlu

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One or more keywords matched the following properties of Mutlu, Gokhan M.

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keywords Pulmonary Fibrosis
overview Dr. Mutlu is Professor of Medicine and Chief of the Section of Pulmonary and Critical Care Medicine at the University of Chicago. He is also the principal investigator/director of the NIH T32 Research training in respiratory biology. Dr. Mutlu's research focuses on the mechanisms of acute lung injury, and pulmonary fibrosis. Specifically, his laboratory is interested in understanding the role of macrophage and fibroblast metabolism including mitochondria in the pathogenesis of acute lung injury and pulmonary fibrosis. Dr. Mutlu's laboratory has extensive expertise with in vitro cell based methods including bioenergetics and in vivo models of acute lung injury (influenza, LPS, bacterial pneumonia and particulate matter) and pulmonary fibrosis (bleomycin).

One or more keywords matched the following items that are connected to Mutlu, Gokhan M.

Item TypeName
Concept Idiopathic Pulmonary Fibrosis
Academic Article Proteasomal regulation of pulmonary fibrosis.
Academic Article Wnt coreceptor Lrp5 is a driver of idiopathic pulmonary fibrosis.
Academic Article Proapoptotic Bid is required for pulmonary fibrosis.
Academic Article Nuclear ß-catenin is increased in systemic sclerosis pulmonary fibrosis and promotes lung fibroblast migration and proliferation.
Academic Article Proteasomal inhibition after injury prevents fibrosis by modulating TGF-ß(1) signalling.
Academic Article Lung-specific loss of a3 laminin worsens bleomycin-induced pulmonary fibrosis.
Academic Article Asbestos-induced pulmonary fibrosis is augmented in 8-oxoguanine DNA glycosylase knockout mice.
Academic Article Flow cytometric analysis of macrophages and dendritic cell subsets in the mouse lung.
Academic Article Regulation of myofibroblast differentiation by cardiac glycosides.
Academic Article SIRT3 blocks myofibroblast differentiation and pulmonary fibrosis by preventing mitochondrial DNA damage.
Academic Article Transforming Growth Factor (TGF)-ß Promotes de Novo Serine Synthesis for Collagen Production.
Academic Article Inhibition of Phosphoglycerate Dehydrogenase Attenuates Bleomycin-induced Pulmonary Fibrosis.
Academic Article P311 Promotes Lung Fibrosis via Stimulation of Transforming Growth Factor-ß1, -ß2, and -ß3 Translation.
Academic Article Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis.
Academic Article Metabolic requirements of pulmonary fibrosis: role of fibroblast metabolism.

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  • Pulmonary Fibrosis