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Antibodies, Monoclonal, Humanized
MHC-I-restricted melanoma antigen specific TCR-engineered human CD4+ T cells exhibit multifunctional effector and helper responses, in vitro.
Active Immunotherapy of Cancer.
CTLA4 blockade broadens the peripheral T-cell receptor repertoire.
CTLA4 blockade increases Th17 cells in patients with metastatic melanoma.
A rare population of tumor antigen-specific CD4+CD8+ double-positive a? T lymphocytes uniquely provide CD8-independent TCR genes for engineering therapeutic T cells.
Modulation of cell signaling networks after CTLA4 blockade in patients with metastatic melanoma.
Rapid Construction of Antitumor T-cell Receptor Vectors from Frozen Tumors for Engineered T-cell Therapy.
Natural killer T cells in advanced melanoma patients treated with tremelimumab.
Kinetic phases of distribution and tumor targeting by T cell receptor engineered lymphocytes inducing robust antitumor responses.
Dendritic cell-based immunotherapy in prevention and treatment of renal cell carcinoma: efficacy, safety, and activity of Ad-GM?CAIX in immunocompetent mouse models.
CTLA4 blockade induces frequent tumor infiltration by activated lymphocytes regardless of clinical responses in humans.
Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells.
Potent maturation of monocyte-derived dendritic cells after CD40L lentiviral gene delivery.
Host immunity contributes to the anti-melanoma activity of BRAF inhibitors.
Adoptive cell transfer of T-cell receptor-engineered lymphocytes: lessons from recent modeling.
Engineering tumor stromal mechanics for improved T cell therapy.