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Search Results to Richard Koya

This is a "connection" page, showing the details of why an item matched the keywords from your search.


One or more keywords matched the following items that are connected to Koya, Richard

Item TypeName
Concept Combined Modality Therapy
Concept Cytological Techniques
Concept Congresses as Topic
Concept T-Lymphocytes, Helper-Inducer
Concept Immune Tolerance
Concept Lymphocyte Culture Test, Mixed
Concept Mice, Transgenic
Concept Neoplasm Transplantation
Concept Radioactive Tracers
Concept Time Factors
Concept Tomography, X-Ray Computed
Concept Transcription, Genetic
Concept Tryptophan
Concept Tumor Necrosis Factor-alpha
Concept Ion Transport
Concept Testis
Concept Transduction, Genetic
Concept Hematopoietic Stem Cell Transplantation
Concept Th1 Cells
Concept Cell Culture Techniques
Concept Reverse Transcriptase Polymerase Chain Reaction
Concept Tumor Cells, Cultured
Concept Transforming Growth Factor beta
Concept CD4-Positive T-Lymphocytes
Concept Lymphocytes, Tumor-Infiltrating
Concept Stem Cell Transplantation
Concept T-Lymphocyte Subsets
Concept Protein Structure, Tertiary
Concept Receptors, Antigen, T-Cell, alpha-beta
Concept Treatment Outcome
Concept Gene Transfer Techniques
Concept CD8-Positive T-Lymphocytes
Concept Thapsigargin
Concept Th2 Cells
Concept Transgenes
Concept Receptor Protein-Tyrosine Kinases
Concept Genes, T-Cell Receptor
Concept Positron-Emission Tomography
Concept Tumor Escape
Concept Adoptive Transfer
Concept Tissue Distribution
Concept Molecular Targeted Therapy
Concept Natural Killer T-Cells
Concept Cell Engineering
Concept T-Lymphocytes, Cytotoxic
Concept Transfection
Concept Electrophoresis, Gel, Two-Dimensional
Concept Imaging, Three-Dimensional
Concept Genes, Transgenic, Suicide
Concept T-Lymphocytes, Regulatory
Concept TNF-Related Apoptosis-Inducing Ligand
Concept Tumor Microenvironment
Concept Lectins, C-Type
Concept Cell Line, Tumor
Concept ZAP-70 Protein-Tyrosine Kinase
Concept Clinical Trials as Topic
Concept Receptors, Antigen, T-Cell
Concept T-Lymphocytes
Concept Thymus Gland
Concept Transplantation, Autologous
Concept Signal Transduction
Concept Coculture Techniques
Academic Article A novel AKT1 mutant amplifies an adaptive melanoma response to BRAF inhibition.
Academic Article Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy.
Academic Article MHC-I-restricted melanoma antigen specific TCR-engineered human CD4+ T cells exhibit multifunctional effector and helper responses, in vitro.
Academic Article Active Immunotherapy of Cancer.
Academic Article CTLA4 blockade broadens the peripheral T-cell receptor repertoire.
Academic Article Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma.
Academic Article Exposure to a histone deacetylase inhibitor has detrimental effects on human lymphocyte viability and function.
Academic Article Efficient identification of neoantigen-specific T-cell responses in advanced human ovarian cancer.
Academic Article A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells.
Academic Article WHSC1/NSD2 regulates immune infiltration in prostate cancer.
Academic Article CTLA4 blockade increases Th17 cells in patients with metastatic melanoma.
Academic Article Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation.
Academic Article Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance.
Academic Article A rare population of tumor antigen-specific CD4+CD8+ double-positive aß T lymphocytes uniquely provide CD8-independent TCR genes for engineering therapeutic T cells.
Academic Article Multifunctional T-cell analyses to study response and progression in adoptive cell transfer immunotherapy.
Academic Article HSV-sr39TK positron emission tomography and suicide gene elimination of human hematopoietic stem cells and their progeny in humanized mice.
Academic Article Cellular Immunotherapy in the Treatment of Hematopoietic Malignancies.
Academic Article The impact of ex vivo clinical grade activation protocols on human T-cell phenotype and function for the generation of genetically modified cells for adoptive cell transfer therapy.
Academic Article Modulation of cell signaling networks after CTLA4 blockade in patients with metastatic melanoma.
Academic Article Rapid Construction of Antitumor T-cell Receptor Vectors from Frozen Tumors for Engineered T-cell Therapy.
Academic Article BRAF inhibitor vemurafenib improves the antitumor activity of adoptive cell immunotherapy.
Academic Article Mature neutrophils suppress T cell immunity in ovarian cancer microenvironment.
Academic Article Natural killer T cells in advanced melanoma patients treated with tremelimumab.
Academic Article Kinetic phases of distribution and tumor targeting by T cell receptor engineered lymphocytes inducing robust antitumor responses.
Academic Article Dendritic cell-based immunotherapy in prevention and treatment of renal cell carcinoma: efficacy, safety, and activity of Ad-GM·CAIX in immunocompetent mouse models.
Academic Article CTLA4 blockade induces frequent tumor infiltration by activated lymphocytes regardless of clinical responses in humans.
Academic Article Antitumor effects of the investigational selective MEK inhibitor TAK733 against cutaneous and uveal melanoma cell lines.
Academic Article Transduction of acute myeloid leukemia cells with third generation self-inactivating lentiviral vectors expressing CD80 and GM-CSF: effects on proliferation, differentiation, and stimulation of allogeneic and autologous anti-leukemia immune responses.
Academic Article Inhibition of CSF-1 receptor improves the antitumor efficacy of adoptive cell transfer immunotherapy.
Academic Article Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance.
Academic Article Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells.
Academic Article A cloning method for caspase substrates that uses the yeast two-hybrid system: cloning of the antiapoptotic gene gelsolin.
Academic Article Gelsolin inhibits apoptosis by blocking mitochondrial membrane potential loss and cytochrome c release.
Academic Article Human antigen-specific regulatory T cells generated by T cell receptor gene transfer.
Academic Article Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines.
Academic Article Lentiviral vectors with CMV or MHCII promoters administered in vivo: immune reactivity versus persistence of expression.
Academic Article Measurement and Quantitative Characterization of Whole-Body Pharmacokinetics of Exogenously Administered T Cells in Mice.
Academic Article Distinct immunological mechanisms of CTLA-4 and PD-1 blockade revealed by analyzing TCR usage in blood lymphocytes.
Academic Article Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF(V600E) melanoma.
Academic Article Chromosomal assignment of a novel human gene D40.
Academic Article A novel series of conferences tackling the hurdles confronting the translation of novel cancer immunotherapies.
Academic Article Human gelsolin prevents apoptosis by inhibiting apoptotic mitochondrial changes via closing VDAC.
Academic Article CD4+CD25- T cells transduced to express MHC class I-restricted epitope-specific TCR synthesize Th1 cytokines and exhibit MHC class I-restricted cytolytic effector function in a human melanoma model.
Academic Article The TLR-7 agonist, imiquimod, enhances dendritic cell survival and promotes tumor antigen-specific T cell priming: relation to central nervous system antitumor immunity.
Academic Article Gelsolin functions as a metastasis suppressor in B16-BL6 mouse melanoma cells and requirement of the carboxyl-terminus for its effect.
Academic Article Potent maturation of monocyte-derived dendritic cells after CD40L lentiviral gene delivery.
Academic Article siRNA knockdown of ribonucleotide reductase inhibits melanoma cell line proliferation alone or synergistically with temozolomide.
Academic Article Decitabine immunosensitizes human gliomas to NY-ESO-1 specific T lymphocyte targeting through the Fas/Fas ligand pathway.
Academic Article The use of lentiviral vectors in gene therapy of leukemia: combinatorial gene delivery of immunomodulators into leukemia cells by state-of-the-art vectors.
Academic Article Analysis of the value of empiric vancomycin administration in febrile neutropenia occurring after autologous peripheral blood stem cell transplants.
Academic Article Preexisting MEK1 exon 3 mutations in V600E/KBRAF melanomas do not confer resistance to BRAF inhibitors.
Academic Article RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors.
Academic Article Monocytes transduced with lentiviral vectors expressing hepatitis C virus non-structural proteins and differentiated into dendritic cells stimulate multi-antigenic CD8(+) T cell responses.
Academic Article Synthesis, Tumor Specificity, and Photosensitizing Efficacy of Erlotinib-Conjugated Chlorins and Bacteriochlorins: Identification of a Highly Effective Candidate for Photodynamic Therapy of Cancer.
Academic Article T cell receptor (TCR)-transgenic CD8 lymphocytes rendered insensitive to transforming growth factor beta (TGFß) signaling mediate superior tumor regression in an animal model of adoptive cell therapy.
Academic Article Immune rejection in a humanized model of murine prostate cancer.
Academic Article Molecular mechanism of MART-1+/A*0201+ human melanoma resistance to specific CTL-killing despite functional tumor-CTL interaction.
Academic Article Host immunity contributes to the anti-melanoma activity of BRAF inhibitors.
Academic Article Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032.
Academic Article Immunosensitization with a Bcl-2 small molecule inhibitor.
Academic Article Isolation of cDNAs that cover the entire coding region of a novel human protein D40.
Academic Article Neoantigens retention in patient derived xenograft models mediates autologous T cells activation in ovarian cancer.
Academic Article Tunable-combinatorial mechanisms of acquired resistance limit the efficacy of BRAF/MEK cotargeting but result in melanoma drug addiction.
Academic Article Inhibition of Alzheimer's amyloid-beta peptide-induced reduction of mitochondrial membrane potential and neurotoxicity by gelsolin.
Academic Article Adoptive cell transfer of T-cell receptor-engineered lymphocytes: lessons from recent modeling.
Academic Article Inhibition of colony stimulating factor-1 receptor improves antitumor efficacy of BRAF inhibition.
Academic Article Host immunity contributes to the anti-melanoma activity of BRAF inhibitors.
Academic Article Modular nucleic acid assembled p/MHC microarrays for multiplexed sorting of antigen-specific T cells.
Academic Article Frequent expression of new cancer/testis gene D40/AF15q14 in lung cancers of smokers.
Academic Article Making dendritic cells from the inside out: lentiviral vector-mediated gene delivery of granulocyte-macrophage colony-stimulating factor and interleukin 4 into CD14+ monocytes generates dendritic cells in vitro.
Academic Article Engineered microenvironment for the study of myofibroblast mechanobiology.
Academic Article CXCR6 by increasing retention of memory CD8+ T cells in the ovarian tumor microenvironment promotes immunosurveillance and control of ovarian cancer.
Academic Article Engineering tumor stromal mechanics for improved T cell therapy.
Academic Article Metabolic adaptation of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses.
Academic Article Tcf-1 protects anti-tumor TCR-engineered CD8+ T-cells from GzmB mediated self-destruction.

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