Item Type | Name |
Concept
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Amino Acid Sequence
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Concept
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Base Sequence
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Concept
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Genes, Regulator
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Concept
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Gene Expression Regulation
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Concept
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Genes, Bacterial
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Concept
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Oncogenes
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Concept
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Molecular Sequence Data
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Concept
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Repetitive Sequences, Nucleic Acid
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Concept
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Nucleic Acid Conformation
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Concept
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Operon
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Concept
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Genome
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Concept
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Sequence Homology, Amino Acid
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Concept
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Gene Rearrangement
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Concept
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Gene Library
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Concept
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RNA Splice Sites
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Concept
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Up-Regulation
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Concept
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Genes, Tumor Suppressor
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Concept
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Genome, Bacterial
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Concept
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Gene Expression
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Concept
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Genes, Reporter
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Concept
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Consensus Sequence
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Concept
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Gene Deletion
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Concept
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Gene Expression Regulation, Developmental
|
Concept
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Histone Code
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Concept
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Catalytic Domain
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Concept
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Gene Expression Profiling
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Concept
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Regulatory Elements, Transcriptional
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Concept
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Down-Regulation
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Concept
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Molecular Structure
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Concept
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Genome, Human
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Concept
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Gene Expression Regulation, Enzymologic
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Concept
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Gene Expression Regulation, Leukemic
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Concept
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Gene Expression Regulation, Plant
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Concept
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Gene Knockdown Techniques
|
Concept
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Gene Dosage
|
Concept
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Structural Homology, Protein
|
Concept
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Gene Fusion
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Concept
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Transcriptome
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Concept
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Epistasis, Genetic
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Concept
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Gene Expression Regulation, Bacterial
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Concept
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Gene Expression Regulation, Neoplastic
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Concept
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Conserved Sequence
|
Concept
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Regulon
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Concept
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Polymorphism, Single Nucleotide
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Concept
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Quantitative Trait Loci
|
Concept
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Cystine Knot Motifs
|
Concept
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Nucleotide Motifs
|
Academic Article
|
The oxidation-sensing regulator (MosR) is a new redox-dependent transcription factor in Mycobacterium tuberculosis.
|
Academic Article
|
Golden pigment production and virulence gene expression are affected by metabolisms in Staphylococcus aureus.
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Academic Article
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A new oxidative sensing and regulation pathway mediated by the MgrA homologue SarZ in Staphylococcus aureus.
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Academic Article
|
Crystal structures of the reduced, sulfenic acid, and mixed disulfide forms of SarZ, a redox active global regulator in Staphylococcus aureus.
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Academic Article
|
Expression of multidrug resistance efflux pump gene norA is iron responsive in Staphylococcus aureus.
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Academic Article
|
Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia.
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Academic Article
|
HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis.
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Academic Article
|
TET1 plays an essential oncogenic role in MLL-rearranged leukemia.
|
Academic Article
|
Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR.
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Academic Article
|
Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis.
|
Academic Article
|
Unique features of the m6A methylome in Arabidopsis thaliana.
|
Academic Article
|
N6-methyladenosine-dependent regulation of messenger RNA stability.
|
Academic Article
|
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility.
|
Academic Article
|
Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome.
|
Academic Article
|
Gene expression regulation mediated through reversible m6A RNA methylation.
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Academic Article
|
Molecular mechanisms of two-component system RhpRS regulating type III secretion system in Pseudomonas syringae.
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Academic Article
|
Dynamic RNA modifications in posttranscriptional regulation.
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Academic Article
|
Aureusimines in Staphylococcus aureus are not involved in virulence.
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Academic Article
|
N6-methyldeoxyadenosine marks active transcription start sites in Chlamydomonas.
|
Academic Article
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The Pseudomonas aeruginosa global regulator VqsR directly inhibits QscR to control quorum-sensing and virulence gene expression.
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Academic Article
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A highly sensitive and genetically encoded fluorescent reporter for ratiometric monitoring of quinones in living cells.
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Academic Article
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Quorum-sensing agr mediates bacterial oxidation response via an intramolecular disulfide redox switch in the response regulator AgrA.
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Academic Article
|
Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance.
|
Academic Article
|
Reversible RNA adenosine methylation in biological regulation.
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Academic Article
|
Pseudomonas aeruginosa OspR is an oxidative stress sensing regulator that affects pigment production, antibiotic resistance and dissemination during infection.
|
Academic Article
|
Steady-state hydrogen peroxide induces glycolysis in Staphylococcus aureus and Pseudomonas aeruginosa.
|
Academic Article
|
Reading RNA methylation codes through methyl-specific binding proteins.
|
Academic Article
|
Targeting MgrA-mediated virulence regulation in Staphylococcus aureus.
|
Academic Article
|
N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency.
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Academic Article
|
RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation.
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Academic Article
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Efficient and quantitative high-throughput tRNA sequencing.
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Academic Article
|
Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation.
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Academic Article
|
RNA epigenetics--chemical messages for posttranscriptional gene regulation.
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Academic Article
|
Nucleic Acid Modifications in Regulation of Gene Expression.
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Academic Article
|
Identification of MLL-fusion/MYC?miR-26?TET1 signaling circuit in MLL-rearranged leukemia.
|
Academic Article
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Structure and mechanism of the essential two-component signal-transduction system WalKR in Staphylococcus aureus.
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Academic Article
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A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations.
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Academic Article
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ALKBH1-Mediated tRNA Demethylation Regulates Translation.
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Academic Article
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Post-transcriptional gene regulation by mRNA modifications.
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Academic Article
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The emerging biology of RNA post-transcriptional modifications.
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Academic Article
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DNA N6-methyladenine in metazoans: functional epigenetic mark or bystander?
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Academic Article
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Dynamic RNA Modifications in Gene Expression Regulation.
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Academic Article
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Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning.
|
Academic Article
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Chemical Modifications in the Life of an mRNA Transcript.
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Academic Article
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RNA modifications modulate gene expression during development.
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Academic Article
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RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia.
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Academic Article
|
Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm.
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Academic Article
|
m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer.
|
Academic Article
|
Single base resolution mapping of 2'-O-methylation sites in human mRNA and in 3' terminal ends of small RNAs.
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Academic Article
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Identifying the m6A Methylome by Affinity Purification and Sequencing.
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Academic Article
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YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs.
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Academic Article
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Phasing Gene Expression: mRNA N6-Methyladenosine Regulates Temporal Progression of Mammalian Cortical Neurogenesis.
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Academic Article
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Publisher Correction: Post-transcriptional gene regulation by mRNA modifications.
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Academic Article
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Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation.
|
Grant
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Regulation of IL-6 and DNA and RNA methylation by PM-induced mitochondrial ROS
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Grant
|
Mechanisms of Pancreatic Cancer Inhibition by SPARC
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Academic Article
|
Special Issue on Regulating the Central Dogma.
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Academic Article
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Inhibition of Copper Transport Induces Apoptosis in Triple-Negative Breast Cancer Cells and Suppresses Tumor Angiogenesis.
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Academic Article
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Regulation of Gene Expression by N6-methyladenosine in Cancer.
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Academic Article
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METTL14 is essential for ß-cell survival and insulin secretion.
|
Academic Article
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Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers.
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Academic Article
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FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export.
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Academic Article
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Detailed modeling of positive selection improves detection of cancer driver genes.
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Academic Article
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Site-specific m6A editing.
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Academic Article
|
Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG.
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Academic Article
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N6-Deoxyadenosine Methylation in Mammalian Mitochondrial DNA.
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Academic Article
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Kethoxal-assisted single-stranded DNA sequencing captures global transcription dynamics and enhancer activity in situ.
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Academic Article
|
A New Model of Spontaneous Colitis in Mice Induced by Deletion of an RNA m6A Methyltransferase Component METTL14 in T Cells.
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Academic Article
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N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation.
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Academic Article
|
A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation.
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Academic Article
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Chromatin and transcriptional regulation by reversible RNA methylation.
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Academic Article
|
Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis.
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Academic Article
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Functional analysis of a SOX10 gene mutation associated with Waardenburg syndrome II.
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Academic Article
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Wnt signaling pathway involvement in genotypic and phenotypic variations in Waardenburg syndrome type 2 with MITF mutations.
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Academic Article
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Identification and functional analysis of a novel mutation in the SOX10 gene associated with Waardenburg syndrome type IV.
|
Academic Article
|
METTL14 facilitates global genome repair and suppresses skin tumorigenesis.
|
Academic Article
|
FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs and mouse development.
|
Academic Article
|
Exon architecture controls mRNA m6A suppression and gene expression.
|
Academic Article
|
m6A-SAC-seq for quantitative whole transcriptome m6A profiling.
|
Concept
|
Gene Editing
|
Concept
|
Gene Ontology
|
Concept
|
Clustered Regularly Interspaced Short Palindromic Repeats
|
Grant
|
Discovering the epigenetics of RNA modifications
|
Grant
|
RNA methylation and regulatory T cells
|
Grant
|
Interrogation of dynamic RNA modifications in beta cells in type 1 diabetes
|
Grant
|
Recognition and mechanism of N6-methyl adenosine modifications
|
Grant
|
Global Cysteine Modifications in Human Pathogens
|
Grant
|
Direct Oxidative Nucleic Acids Demethylation
|
Grant
|
Base-resolution sequencing of m6A in RNA
|
Grant
|
Direct Oxidative Nucleic Acids Demethylation
|
Academic Article
|
Splice epitranscriptomics and DNA damage repair together: ALKBH5-m6A-SF3B1 regulation in leukemic transformation.
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Academic Article
|
Nm-Mut-seq: a base-resolution quantitative method for mapping transcriptome-wide 2'-O-methylation.
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Academic Article
|
YTHDF2 inhibition potentiates radiotherapy antitumor efficacy.
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Academic Article
|
BID-seq for transcriptome-wide quantitative sequencing of mRNA pseudouridine at base resolution.
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Academic Article
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Light-induced LLPS of the CRY2/SPA1/FIO1 complex regulating mRNA methylation and chlorophyll homeostasis in Arabidopsis.
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Academic Article
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mRNA accessibility within mRNPs as a determinant of gene expression.
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Academic Article
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5-Hydroxymethylcytosine Profiling of Cell-Free DNA Identifies Bivalent Genes That Are Prognostic of Survival in High-Risk Neuroblastoma.
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Academic Article
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Small-molecule inhibition of the METTL3/METTL14 complex suppresses neuroblastoma tumor growth and promotes differentiation.
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Academic Article
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Quantitative profiling of m6A at single base resolution across the life cycle of rice and Arabidopsis.
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Grant
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Critical roles of RNA m5C-MBD6-H2AK119ub deubiquitylation axis in TET2-mediated HSC regulation
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