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One or more keywords matched the following properties of Stephens, Matthew
overview My lab works on a wide variety of problems at the interface of Statistics and Genetics. We often tackle problems where novel statistical methods are required, or can learn something new compared with existing approaches. Thus, much of our research involves developing new statistical methodology, many of which have a non-trivial computational component. People in my lab tend to come from a quantitative background (e.g., Statistics, Computer Science), with varying levels of formal or informal Biology training.
One or more keywords matched the following items that are connected to Stephens, Matthew
Item TypeName
Concept Genetics, Behavioral
Concept Factor Analysis, Statistical
Concept Genetics, Medical
Concept Genetics, Population
Concept Models, Statistical
Concept Data Interpretation, Statistical
Concept Statistical Distributions
Academic Article Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies.
Academic Article Traces of human migrations in Helicobacter pylori populations.
Academic Article The effects of genotype-dependent recombination, and transmission asymmetry, on linkage disequilibrium.
Academic Article Genome-wide detection and characterization of positive selection in human populations.
Academic Article Practical issues in imputation-based association mapping.
Academic Article Exon-specific QTLs skew the inferred distribution of expression QTLs detected using gene expression array data.
Academic Article Genes mirror geography within Europe.
Academic Article A statistical framework for joint eQTL analysis in multiple tissues.
Academic Article Insights into recombination from population genetic variation.
Academic Article Analysis of population structure: a unifying framework and novel methods based on sparse factor analysis.
Academic Article Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation.
Academic Article msHOT: modifying Hudson's ms simulator to incorporate crossover and gene conversion hotspots.
Academic Article Fast and accurate estimation of the population-scaled mutation rate, theta, from microsatellite genotype data.
Academic Article Probabilistic segmentation and intensity estimation for microarray images.
Academic Article A unified framework for association analysis with multiple related phenotypes.
Academic Article Statistical inference of in vivo properties of human DNA methyltransferases from double-stranded methylation patterns.
Academic Article An estimate of the average number of recessive lethal mutations carried by humans.
Academic Article Imputation-based analysis of association studies: candidate regions and quantitative traits.
Academic Article Bayesian statistical methods for genetic association studies.
Academic Article fastSTRUCTURE: variational inference of population structure in large SNP data sets.
Academic Article A comparison of phasing algorithms for trios and unrelated individuals.
Academic Article A comparison of bayesian methods for haplotype reconstruction from population genotype data.
Academic Article A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase.
Academic Article Linkage disequilibrium-based quality control for large-scale genetic studies.
Academic Article Modeling linkage disequilibrium and identifying recombination hotspots using single-nucleotide polymorphism data.
Academic Article A Simple Model-Based Approach to Inferring and Visualizing Cancer Mutation Signatures.
Academic Article Visualizing spatial population structure with estimated effective migration surfaces.
Academic Article New evidence for hybrid zones of forest and savanna elephants in Central and West Africa.
Academic Article False discovery rates: a new deal.
Academic Article Empirical Bayes shrinkage and false discovery rate estimation, allowing for unwanted variation.
Academic Article Flexible statistical methods for estimating and testing effects in genomic studies with multiple conditions.
Academic Article Genotyping Polyploids from Messy Sequencing Data.
Academic Article Accurate genomic prediction of Coffea canephora in multiple environments using whole-genome statistical models.
Academic Article Estimating recent migration and population-size surfaces.
Academic Article Bayesian multivariate reanalysis of large genetic studies identifies many new associations.
Academic Article Mendelian randomization accounting for correlated and uncorrelated pleiotropic effects using genome-wide summary statistics.
Grant Multipoint and significance methods for genome-wide association studies
Grant Statistical analysis of gene expression quantitative trait loci (eQTL)
Grant Genome analysis: statistical methods and applications
Academic Article Flexible statistical methods for estimating and testing effects in genomic studies with multiple conditions.
Grant Genome analysis: statistical methods and applications
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  • Statistical
  • Genetics