Item Type | Name |
Concept
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Leukemia, Erythroblastic, Acute
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Concept
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Leukemia
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Concept
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Leukemia, Mast-Cell
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Concept
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Leukemia, Radiation-Induced
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Concept
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Leukemia, Lymphocytic, Chronic, B-Cell
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Concept
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Leukemia, Myeloid
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Concept
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Leukemia, Myeloid, Acute
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Concept
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Leukemia, Promyelocytic, Acute
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Concept
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Leukemia, Myelomonocytic, Chronic
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Concept
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Precursor Cell Lymphoblastic Leukemia-Lymphoma
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Concept
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Myeloid-Lymphoid Leukemia Protein
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Concept
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Leukemia, Myelogenous, Chronic, BCR-ABL Positive
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Academic Article
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TTID: A novel gene at 5q31 encoding a protein with titin-like features.
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Academic Article
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Molecular characterization of KLHL3, a human homologue of the Drosophila kelch gene.
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Academic Article
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cDNA cloning and genomic structure of three genes localized to human chromosome band 5q31 encoding potential nuclear proteins.
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Academic Article
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Expression profiling of CD34+ hematopoietic stem/ progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia.
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Academic Article
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Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q).
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Academic Article
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Successful autologous stem cell collection in patients with chronic myeloid leukemia in complete cytogenetic response, with quantitative measurement of BCR-ABL expression in blood, marrow, and apheresis products.
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Academic Article
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A phase I biological study of MG98, an oligodeoxynucleotide antisense to DNA methyltransferase 1, in patients with high-risk myelodysplasia and acute myeloid leukemia.
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Academic Article
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Outcomes of patients with AML and MDS who relapse or progress after reduced intensity allogeneic hematopoietic cell transplantation.
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Academic Article
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Therapy-related myeloid leukemia.
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Academic Article
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Deletion of the der(9q) in chronic myeloid leukemia: the controversy continues.
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Academic Article
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Allogeneic stem cell transplantation with alemtuzumab-based conditioning for patients with advanced chronic myelogenous leukemia.
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Academic Article
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Patterns and kinetics of T-cell chimerism after allo transplant with alemtuzumab-based conditioning: mixed chimerism protects from GVHD, but does not portend disease recurrence.
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Academic Article
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Results from a randomized trial of salvage chemotherapy followed by lestaurtinib for patients with FLT3 mutant AML in first relapse.
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Academic Article
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Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.
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Academic Article
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High dose cytarabine and mitoxantrone: an effective induction regimen for high-risk acute myeloid leukemia (AML).
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Academic Article
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Gene mutations, epigenetic dysregulation, and personalized therapy in myeloid neoplasia: are we there yet?
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Academic Article
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A drug that stops traffic at the nuclear border.
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Academic Article
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Phase I-II study of clofarabine-melphalan-alemtuzumab conditioning for allogeneic hematopoietic cell transplantation.
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Academic Article
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The histone code and treatments for acute myeloid leukemia.
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Academic Article
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Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
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Academic Article
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Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia.
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Academic Article
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An integrated genomic approach to the assessment and treatment of acute myeloid leukemia.
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Academic Article
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Identification and molecular characterization of a novel 3′ mutation in RUNX1 in a family with familial platelet disorder.
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Academic Article
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HMGA2 levels in CML: reflective of miRNA gene regulation in a hematopoietic tumor?
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Academic Article
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Profiles in leukemia.
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Academic Article
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Fludarabine, melphalan, and alemtuzumab conditioning in adults with standard-risk advanced acute myeloid leukemia and myelodysplastic syndrome.
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Academic Article
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A phase I and pharmacokinetic study of XK469R (NSC 698215), a quinoxaline phenoxypropionic acid derivative, in patients with refractory acute leukemia.
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Academic Article
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Implications of FLT3 mutations in the therapy of acute myeloid leukemia.
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Academic Article
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The identification and characterisation of novel KIT transcripts in aggressive mast cell malignancies and normal CD34+ cells.
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Academic Article
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Getting to the root of the stem cell in mutated chronic myeloid leukemia.
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Academic Article
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Identifying familial myelodysplastic/acute leukemia predisposition syndromes through hematopoietic stem cell transplantation donors with thrombocytopenia.
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Academic Article
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2-Hydroxyglutarate in IDH mutant acute myeloid leukemia: predicting patient responses, minimal residual disease and correlations with methylcytosine and hydroxymethylcytosine levels.
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Academic Article
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Proposal for the clinical detection and management of patients and their family members with familial myelodysplastic syndrome/acute leukemia predisposition syndromes.
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Academic Article
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Cell characterization using a protein-functionalized pore.
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Academic Article
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A novel clofarabine bridge strategy facilitates allogeneic transplantation in patients with relapsed/refractory leukemia and high-risk myelodysplastic syndromes.
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Academic Article
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Node-pore sensing enables label-free surface-marker profiling of single cells.
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Academic Article
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Inherited predisposition to acute myeloid leukemia.
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Academic Article
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DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.
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Academic Article
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Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms.
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Academic Article
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Recognizing familial myeloid leukemia in adults.
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Academic Article
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Large conserved domains of low DNA methylation maintained by Dnmt3a.
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Academic Article
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Familial myelodysplastic syndrome/acute leukemia syndromes: a review and utility for translational investigations.
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Academic Article
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On the origin of leukemic species.
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Academic Article
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The mechanistic role of DNA methylation in myeloid leukemogenesis.
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Academic Article
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TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor-Binding Sites in Chronic Myelomonocytic Leukemia.
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Academic Article
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Genomic analysis of germ line and somatic variants in familial myelodysplasia/acute myeloid leukemia.
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Academic Article
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Inherited mutations in cancer susceptibility genes are common among survivors of breast cancer who develop therapy-related leukemia.
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Academic Article
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Increased DNA methylation of Dnmt3b targets impairs leukemogenesis.
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Academic Article
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Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset and lymphoid malignancies.
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Academic Article
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Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes.
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Academic Article
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Clinical utility of gene panel-based testing for hereditary myelodysplastic syndrome/acute leukemia predisposition syndromes.
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Academic Article
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Genetic predisposition to leukemia and other hematologic malignancies.
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Academic Article
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Efficacy of single-agent decitabine in relapsed and refractory acute myeloid leukemia.
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Academic Article
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Germline ETV6 mutations and predisposition to hematological malignancies.
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Academic Article
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Genetic predisposition to hematologic malignancies: management and surveillance.
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Academic Article
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Therapy-related myeloid neoplasms: when genetics and environment collide.
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Academic Article
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Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.
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Academic Article
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Hereditary Myelodysplastic Syndrome and Acute Myeloid Leukemia: Diagnosis, Questions, and Controversies.
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Academic Article
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Treatment of Acute Promyelocytic Leukemia in Adults.
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Academic Article
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MBD4: guardian of the epigenetic galaxy.
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Academic Article
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Reduced-Intensity Allogeneic Transplant for Acute Myeloid Leukemia and Myelodysplastic Syndrome Using Combined CD34-Selected Haploidentical Graft and a Single Umbilical Cord Unit Compared with Matched Unrelated Donor Stem Cells in Older Adults.
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Academic Article
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Identifying patients with genetic predisposition to acute myeloid leukemia.
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Academic Article
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A phase I study of selinexor in combination with high-dose cytarabine and mitoxantrone for remission induction in patients with acute myeloid leukemia.
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Academic Article
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FouNdER mutations confer risk for leukemias.
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Academic Article
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Correct application of variant classification guidelines in germline RUNX1 mutated disorders to assist clinical diagnosis.
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Academic Article
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ClinGen Myeloid Malignancy Variant Curation Expert Panel recommendations for germline RUNX1 variants.
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Academic Article
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A phase 1 study of azacitidine with high-dose cytarabine and mitoxantrone in high-risk acute myeloid leukemia.
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Academic Article
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RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML.
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Academic Article
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Breaking the spatial constraint between neighboring zinc fingers: a new germline mutation in GATA2 deficiency syndrome.
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Academic Article
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Germline mutations in MDS/AML predisposition disorders.
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Academic Article
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Germline variants drive myelodysplastic syndrome in young adults.
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Academic Article
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Targeted gene panels identify a high frequency of pathogenic germline variants in patients diagnosed with a hematological malignancy and at least one other independent cancer.
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Academic Article
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Clinical features and survival outcomes in patients with chronic myelomonocytic leukemia arising in the context of germline predisposition syndromes.
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Academic Article
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The RUNX1 database (RUNX1db): establishment of an expert curated RUNX1 registry and genomics database as a public resource for familial platelet disorder with myeloid malignancy.
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Academic Article
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BET inhibitors enhance embryonic and fetal globin expression in erythroleukemia cell lines.
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Academic Article
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Germline CHEK2 and ATM Variants in Myeloid and Other Hematopoietic Malignancies.
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Academic Article
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International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data.
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Academic Article
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Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN.
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Academic Article
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Efficacy and tolerability of a modified pediatric-inspired intensive regimen for acute lymphoblastic leukemia in older adults.
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Academic Article
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Clinical and molecular response of acute myeloid leukemia harboring non-canonical FLT3 N676K driver mutations to contemporary FLT3 inhibitors.
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Academic Article
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Germ line DDX41 mutations define a unique subtype of myeloid neoplasms.
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Academic Article
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DDX41-associated susceptibility to myeloid neoplasms.
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Academic Article
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Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia.
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Academic Article
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Significance of hereditary gene alterations for the pathogenesis of adult bone marrow failure versus myeloid neoplasia.
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Academic Article
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Classification of rare pediatric myeloid neoplasia-Quo vadis?
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Academic Article
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(R)-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in IDH-Mutant Cancers.
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Grant
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The Role of DNMT3B in the DNA Methylation of Cancer Cells
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Academic Article
|
Somatic mutational landscape of hereditary hematopoietic malignancies caused by germline variants in RUNX1, GATA2, and DDX41.
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Academic Article
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Acute Lymphoblastic Leukemia with Myeloid Mutations Is a High-Risk Disease Associated with Clonal Hematopoiesis.
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Academic Article
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Insights into the Molecular Mechanisms of Genetic Predisposition to Hematopoietic Malignancies: The Importance of Gene-Environment Interactions.
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