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One or more keywords matched the following items that are connected to Roizman, Bernard
Item TypeName
Concept Creatine Kinase
Concept Protein-Tyrosine Kinases
Concept Protein Kinases
Concept src-Family Kinases
Concept DNA-Activated Protein Kinase
Concept MAP Kinase Kinase Kinases
Concept eIF-2 Kinase
Concept Janus Kinase 1
Concept Cyclin-Dependent Kinase 4
Concept Mitogen-Activated Protein Kinase Kinases
Concept CDC2 Protein Kinase
Concept Cyclin-Dependent Kinases
Concept Phosphatidylinositol 3-Kinases
Concept MAP Kinase Signaling System
Concept Extracellular Signal-Regulated MAP Kinases
Concept I-kappa B Kinase
Concept Cyclic AMP-Dependent Protein Kinase Type II
Concept CDC2-CDC28 Kinases
Concept Cyclin-Dependent Kinase 6
Concept Cyclic AMP-Dependent Protein Kinases
Concept Cyclin-Dependent Kinase 9
Concept Protein Kinase Inhibitors
Concept p38 Mitogen-Activated Protein Kinases
Concept Cyclin-Dependent Kinase 2
Academic Article Role of cyclin D3 in the biology of herpes simplex virus 1 ICPO.
Academic Article Second-site mutation outside of the U(S)10-12 domain of Deltagamma(1)34.5 herpes simplex virus 1 recombinant blocks the shutoff of protein synthesis induced by activated protein kinase R and partially restores neurovirulence.
Academic Article E2F proteins are posttranslationally modified concomitantly with a reduction in nuclear binding activity in cells infected with herpes simplex virus 1.
Academic Article Posttranslational processing of infected cell protein 22 mediated by viral protein kinases is sensitive to amino acid substitutions at distant sites and can be cell-type specific.
Academic Article The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins.
Academic Article cdc2 cyclin-dependent kinase binds and phosphorylates herpes simplex virus 1 U(L)42 DNA synthesis processivity factor.
Academic Article Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts.
Academic Article The role of cdc2 in the expression of herpes simplex virus genes.
Academic Article Herpes simplex virus 1 activates cdc2 to recruit topoisomerase II alpha for post-DNA synthesis expression of late genes.
Academic Article U(S)3 protein kinase of herpes simplex virus 1 blocks caspase 3 activation induced by the products of U(S)1.5 and U(L)13 genes and modulates expression of transduced U(S)1.5 open reading frame in a cell type-specific manner.
Academic Article Characterization of the novel E3 ubiquitin ligase encoded in exon 3 of herpes simplex virus-1-infected cell protein 0.
Academic Article Activation of NF-kappaB in cells productively infected with HSV-1 depends on activated protein kinase R and plays no apparent role in blocking apoptosis.
Academic Article The U(S)3 protein kinase blocks apoptosis induced by the d120 mutant of herpes simplex virus 1 at a premitochondrial stage.
Academic Article Posttranslational processing of infected cell proteins 0 and 4 of herpes simplex virus 1 is sequential and reflects the subcellular compartment in which the proteins localize.
Academic Article Herpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosis.
Academic Article Herpes simplex virus 1 gene products occlude the interferon signaling pathway at multiple sites.
Academic Article The carboxyl-terminal domain of RNA polymerase II is phosphorylated by a complex containing cdk9 and infected-cell protein 22 of herpes simplex virus 1.
Academic Article Herpes simplex virus 1 ICP22 regulates the accumulation of a shorter mRNA and of a truncated US3 protein kinase that exhibits altered functions.
Academic Article Protein kinase B/Akt is present in activated form throughout the entire replicative cycle of deltaU(S)3 mutant virus but only at early times after infection with wild-type herpes simplex virus 1.
Academic Article Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1.
Academic Article Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses.
Academic Article State and role of SRC family kinases in replication of herpes simplex virus 1.
Academic Article U(S)3 and U(S)3.5 protein kinases of herpes simplex virus 1 differ with respect to their functions in blocking apoptosis and in virion maturation and egress.
Academic Article Mapping of key functions of the herpes simplex virus 1 U(S)3 protein kinase: the U(S)3 protein can form functional heteromultimeric structures derived from overlapping truncated polypeptides.
Academic Article In transduced cells, the US3 protein kinase of herpes simplex virus 1 precludes activation and induction of apoptosis by transfected procaspase 3.
Academic Article Expression of gamma interferon-dependent genes is blocked independently by virion host shutoff RNase and by US3 protein kinase.
Academic Article Role of cdk9 in the optimization of expression of the genes regulated by ICP22 of herpes simplex virus 1.
Academic Article Cells lacking NF-kappaB or in which NF-kappaB is not activated vary with respect to ability to sustain herpes simplex virus 1 replication and are not susceptible to apoptosis induced by a replication-incompetent mutant virus.
Academic Article The interaction of herpes simplex virus 1 regulatory protein ICP22 with the cdc25C phosphatase is enabled in vitro by viral protein kinases US3 and UL13.
Academic Article Interwoven roles of cyclin D3 and cdk4 recruited by ICP0 and ICP4 in the expression of herpes simplex virus genes.
Academic Article Systemic delivery of (gamma1)34.5-deleted herpes simplex virus-1 selectively targets and treats distant human xenograft tumors that express high MEK activity.
Academic Article US3 protein kinase of HSV-1 cycles between the cytoplasm and nucleus and interacts with programmed cell death protein 4 (PDCD4) to block apoptosis.
Academic Article Role of cellular phosphatase cdc25C in herpes simplex virus 1 replication.
Academic Article The disappearance of cyclins A and B and the increase in activity of the G(2)/M-phase cellular kinase cdc2 in herpes simplex virus 1-infected cells require expression of the alpha22/U(S)1.5 and U(L)13 viral genes.
Academic Article The herpes simplex virus 1 US3 protein kinase blocks caspase-dependent double cleavage and activation of the proapoptotic protein BAD.
Academic Article Oct-1 is posttranslationally modified and exhibits reduced capacity to bind cognate sites at late times after infection with herpes simplex virus 1.
Academic Article ICP0 and the US3 protein kinase of herpes simplex virus 1 independently block histone deacetylation to enable gene expression.
Academic Article Attenuated herpes simplex virus 1 blocks arterial apoptosis and intimal hyperplasia induced by balloon angioplasty and reduced blood flow.
Academic Article ICP0 enables and monitors the function of D cyclins in herpes simplex virus 1 infected cells.
Academic Article The virion host shutoff RNase plays a key role in blocking the activation of protein kinase R in cells infected with herpes simplex virus 1.
Academic Article HSV-1 degrades, stabilizes, requires, or is stung by STING depending on ICP0, the US3 protein kinase, and cell derivation.
Academic Article The stability of herpes simplex virus 1 ICP0 early after infection is defined by the RING finger and the UL13 protein kinase.
Grant MOLECULAR BIOLOGY OF HERPES SIMPLEX VIRUSES
Grant DISSECTION OF THE FUNCTIONS OF HERPES SIMPLEX VIRUS ICPO
Grant FUNCTIONS FOR HERPES SIMPLEX VIRUS ICP22 AND US1.5
Grant The functions of the US3 protein kinase of herpes simplex virus
Grant Dissection of the Functions of Herpes Simplex Virus ICPO
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