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Roizman, Bernard

One or more keywords matched the following items that are connected to Roizman, Bernard

Item Type	Name
Concept	Creatine Kinase
Concept	Protein-Tyrosine Kinases
Concept	Protein Kinases
Concept	src-Family Kinases
Concept	DNA-Activated Protein Kinase
Concept	MAP Kinase Kinase Kinases
Concept	eIF-2 Kinase
Concept	Janus Kinase 1
Concept	Cyclin-Dependent Kinase 4
Concept	Mitogen-Activated Protein Kinase Kinases
Concept	CDC2 Protein Kinase
Concept	Cyclin-Dependent Kinases
Concept	Phosphatidylinositol 3-Kinases
Concept	MAP Kinase Signaling System
Concept	Extracellular Signal-Regulated MAP Kinases
Concept	I-kappa B Kinase
Concept	Cyclic AMP-Dependent Protein Kinase Type II
Concept	CDC2-CDC28 Kinases
Concept	Cyclin-Dependent Kinase 6
Concept	Cyclic AMP-Dependent Protein Kinases
Concept	Cyclin-Dependent Kinase 9
Concept	Protein Kinase Inhibitors
Concept	p38 Mitogen-Activated Protein Kinases
Concept	Cyclin-Dependent Kinase 2
Academic Article	Role of cyclin D3 in the biology of herpes simplex virus 1 ICPO.
Academic Article	Second-site mutation outside of the U(S)10-12 domain of Deltagamma(1)34.5 herpes simplex virus 1 recombinant blocks the shutoff of protein synthesis induced by activated protein kinase R and partially restores neurovirulence.
Academic Article	E2F proteins are posttranslationally modified concomitantly with a reduction in nuclear binding activity in cells infected with herpes simplex virus 1.
Academic Article	Posttranslational processing of infected cell protein 22 mediated by viral protein kinases is sensitive to amino acid substitutions at distant sites and can be cell-type specific.
Academic Article	The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins.
Academic Article	cdc2 cyclin-dependent kinase binds and phosphorylates herpes simplex virus 1 U(L)42 DNA synthesis processivity factor.
Academic Article	Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts.
Academic Article	The role of cdc2 in the expression of herpes simplex virus genes.
Academic Article	Herpes simplex virus 1 activates cdc2 to recruit topoisomerase II alpha for post-DNA synthesis expression of late genes.
Academic Article	U(S)3 protein kinase of herpes simplex virus 1 blocks caspase 3 activation induced by the products of U(S)1.5 and U(L)13 genes and modulates expression of transduced U(S)1.5 open reading frame in a cell type-specific manner.
Academic Article	Characterization of the novel E3 ubiquitin ligase encoded in exon 3 of herpes simplex virus-1-infected cell protein 0.
Academic Article	Activation of NF-kappaB in cells productively infected with HSV-1 depends on activated protein kinase R and plays no apparent role in blocking apoptosis.
Academic Article	The U(S)3 protein kinase blocks apoptosis induced by the d120 mutant of herpes simplex virus 1 at a premitochondrial stage.
Academic Article	Posttranslational processing of infected cell proteins 0 and 4 of herpes simplex virus 1 is sequential and reflects the subcellular compartment in which the proteins localize.
Academic Article	Herpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosis.
Academic Article	Herpes simplex virus 1 gene products occlude the interferon signaling pathway at multiple sites.
Academic Article	The carboxyl-terminal domain of RNA polymerase II is phosphorylated by a complex containing cdk9 and infected-cell protein 22 of herpes simplex virus 1.
Academic Article	Herpes simplex virus 1 ICP22 regulates the accumulation of a shorter mRNA and of a truncated US3 protein kinase that exhibits altered functions.
Academic Article	Protein kinase B/Akt is present in activated form throughout the entire replicative cycle of deltaU(S)3 mutant virus but only at early times after infection with wild-type herpes simplex virus 1.
Academic Article	Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1.
Academic Article	Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses.
Academic Article	State and role of SRC family kinases in replication of herpes simplex virus 1.
Academic Article	U(S)3 and U(S)3.5 protein kinases of herpes simplex virus 1 differ with respect to their functions in blocking apoptosis and in virion maturation and egress.
Academic Article	Mapping of key functions of the herpes simplex virus 1 U(S)3 protein kinase: the U(S)3 protein can form functional heteromultimeric structures derived from overlapping truncated polypeptides.
Academic Article	In transduced cells, the US3 protein kinase of herpes simplex virus 1 precludes activation and induction of apoptosis by transfected procaspase 3.
Academic Article	Expression of gamma interferon-dependent genes is blocked independently by virion host shutoff RNase and by US3 protein kinase.
Academic Article	Role of cdk9 in the optimization of expression of the genes regulated by ICP22 of herpes simplex virus 1.
Academic Article	Cells lacking NF-kappaB or in which NF-kappaB is not activated vary with respect to ability to sustain herpes simplex virus 1 replication and are not susceptible to apoptosis induced by a replication-incompetent mutant virus.
Academic Article	The interaction of herpes simplex virus 1 regulatory protein ICP22 with the cdc25C phosphatase is enabled in vitro by viral protein kinases US3 and UL13.
Academic Article	Interwoven roles of cyclin D3 and cdk4 recruited by ICP0 and ICP4 in the expression of herpes simplex virus genes.
Academic Article	Systemic delivery of (gamma1)34.5-deleted herpes simplex virus-1 selectively targets and treats distant human xenograft tumors that express high MEK activity.
Academic Article	US3 protein kinase of HSV-1 cycles between the cytoplasm and nucleus and interacts with programmed cell death protein 4 (PDCD4) to block apoptosis.
Academic Article	Role of cellular phosphatase cdc25C in herpes simplex virus 1 replication.
Academic Article	The disappearance of cyclins A and B and the increase in activity of the G(2)/M-phase cellular kinase cdc2 in herpes simplex virus 1-infected cells require expression of the alpha22/U(S)1.5 and U(L)13 viral genes.
Academic Article	The herpes simplex virus 1 US3 protein kinase blocks caspase-dependent double cleavage and activation of the proapoptotic protein BAD.
Academic Article	Oct-1 is posttranslationally modified and exhibits reduced capacity to bind cognate sites at late times after infection with herpes simplex virus 1.
Academic Article	ICP0 and the US3 protein kinase of herpes simplex virus 1 independently block histone deacetylation to enable gene expression.
Academic Article	Attenuated herpes simplex virus 1 blocks arterial apoptosis and intimal hyperplasia induced by balloon angioplasty and reduced blood flow.
Academic Article	ICP0 enables and monitors the function of D cyclins in herpes simplex virus 1 infected cells.
Academic Article	The virion host shutoff RNase plays a key role in blocking the activation of protein kinase R in cells infected with herpes simplex virus 1.
Academic Article	HSV-1 degrades, stabilizes, requires, or is stung by STING depending on ICP0, the US3 protein kinase, and cell derivation.
Academic Article	The stability of herpes simplex virus 1 ICP0 early after infection is defined by the RING finger and the UL13 protein kinase.
Grant	MOLECULAR BIOLOGY OF HERPES SIMPLEX VIRUSES
Grant	DISSECTION OF THE FUNCTIONS OF HERPES SIMPLEX VIRUS ICPO
Grant	FUNCTIONS FOR HERPES SIMPLEX VIRUS ICP22 AND US1.5
Grant	The functions of the US3 protein kinase of herpes simplex virus
Grant	Dissection of the Functions of Herpes Simplex Virus ICPO

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