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Kossiakoff, Anthony
One or more keywords matched the following properties of
Kossiakoff, Anthony
Property
Value
keywords
Membrane Proteins
One or more keywords matched the following items that are connected to
Kossiakoff, Anthony
Item Type
Name
Concept
Bacterial Proteins
Concept
Calmodulin-Binding Proteins
Concept
Fungal Proteins
Concept
Chromosomal Proteins, Non-Histone
Concept
Microfilament Proteins
Concept
Nerve Tissue Proteins
Concept
Plant Proteins
Concept
Muscle Proteins
Concept
Proteins
Concept
Protozoan Proteins
Concept
RNA-Binding Proteins
Concept
Oncogene Proteins, Viral
Concept
Green Fluorescent Proteins
Concept
Cell Cycle Proteins
Concept
ras GTPase-Activating Proteins
Concept
Nuclear Pore Complex Proteins
Concept
Arabidopsis Proteins
Concept
Saccharomyces cerevisiae Proteins
Concept
Recombinant Proteins
Concept
Adaptor Proteins, Signal Transducing
Concept
Viral Proteins
Concept
GTP-Binding Proteins
Concept
Antifreeze Proteins
Concept
Antimicrobial Cationic Peptides
Concept
Cation Transport Proteins
Concept
Mutant Proteins
Concept
Escherichia coli Proteins
Concept
Carrier Proteins
Concept
Neoplasm Proteins
Concept
Nuclear Proteins
Concept
Recombinant Fusion Proteins
Concept
Archaeal Proteins
Concept
Membrane Transport Proteins
Concept
Maltose-Binding Proteins
Academic Article
Variability of conformations at crystal contacts in BPTI represent true low-energy structures: correspondence among lattice packing and molecular dynamics structures.
Academic Article
Structural consequences of mutation.
Academic Article
Structural effects induced by mutagenesis affected by crystal packing factors: the structure of a 30-51 disulfide mutant of basic pancreatic trypsin inhibitor.
Academic Article
Crystallization and preliminary X-ray analysis of a 1:1 complex between a designed monomeric interferon-gamma and its soluble receptor.
Academic Article
Crystallization of ovine placental lactogen in a 1:2 complex with the extracellular domain of the rat prolactin receptor.
Academic Article
Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor.
Academic Article
Biosynthetic phage display: a novel protein engineering tool combining chemical and genetic diversity.
Academic Article
Analysis of solvent structure in proteins using neutron D2O-H2O solvent maps: pattern of primary and secondary hydration of trypsin.
Academic Article
Solvent structure in crystals of trypsin determined by X-ray and neutron diffraction.
Academic Article
The 2.0 A structure of bovine interferon-gamma; assessment of the structural differences between species.
Academic Article
Deciphering the role of the electrostatic interactions involving Gly70 in eglin C by total chemical protein synthesis.
Academic Article
Crystals of the complex between human growth hormone and the extracellular domain of its receptor.
Academic Article
The first semi-synthetic serine protease made by native chemical ligation.
Academic Article
The crystal structure of Aq_328 from the hyperthermophilic bacteria Aquifex aeolicus shows an ancestral histone fold.
Academic Article
Dissecting the energetics of protein alpha-helix C-cap termination through chemical protein synthesis.
Academic Article
X-ray structure of snow flea antifreeze protein determined by racemic crystallization of synthetic protein enantiomers.
Academic Article
The 1.38 A crystal structure of DmsD protein from Salmonella typhimurium, a proofreading chaperone on the Tat pathway.
Academic Article
The high- and low-affinity receptor binding sites of growth hormone are allosterically coupled.
Academic Article
Alternative views of functional protein binding epitopes obtained by combinatorial shotgun scanning mutagenesis.
Academic Article
Comprehensive and quantitative mapping of energy landscapes for protein-protein interactions by rapid combinatorial scanning.
Academic Article
The role of protein dynamics in increasing binding affinity for an engineered protein-protein interaction established by H/D exchange mass spectrometry.
Academic Article
Time-controlled microfluidic seeding in nL-volume droplets to separate nucleation and growth stages of protein crystallization.
Academic Article
Exploring the capacity of minimalist protein interfaces: interface energetics and affinity maturation to picomolar KD of a single-domain antibody with a flat paratope.
Academic Article
Mechanism of activation gating in the full-length KcsA K+ channel.
Academic Article
Intramolecular cooperativity in a protein binding site assessed by combinatorial shotgun scanning mutagenesis.
Academic Article
Crystal structure of full-length KcsA in its closed conformation.
Academic Article
A method of solvent structure analysis for proteins using D2O-H2O neutron difference maps.
Academic Article
X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling.
Academic Article
The crystal structure of affinity-matured human growth hormone at 2 A resolution.
Academic Article
Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins.
Academic Article
Protein dynamics investigated by neutron diffraction.
Academic Article
Neutron protein crystallography: advances in methods and applications.
Academic Article
Substance P derivatives as versatile tools for specific delivery of various types of biomolecular cargo.
Academic Article
Crystal structures of subtilisin BPN' variants containing disulfide bonds and cavities: concerted structural rearrangements induced by mutagenesis.
Academic Article
Molecular recognition in biological systems: from activation to inhibition.
Academic Article
Effect of protein packing structure on side-chain methyl rotor conformations.
Academic Article
Racemic crystallography of synthetic protein enantiomers used to determine the X-ray structure of plectasin by direct methods.
Academic Article
The use of neutrons to show how proteins work.
Academic Article
Principal determinants leading to transition state formation of a protein-protein complex, orientation trumps side-chain interactions.
Academic Article
An engineered substance P variant for receptor-mediated delivery of synthetic antibodies into tumor cells.
Academic Article
Characterization of engineered actin binding proteins that control filament assembly and structure.
Academic Article
The application of neutron crystallography to the study of dynamic and and hydration properties of proteins.
Academic Article
Generating conformation-specific synthetic antibodies to trap proteins in selected functional states.
Academic Article
Visualization of arrestin recruitment by a G-protein-coupled receptor.
Academic Article
Probing the functions of the paramyxovirus glycoproteins F and HN with a panel of synthetic antibodies.
Academic Article
Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments.
Academic Article
Nuclear pores. Architecture of the nuclear pore complex coat.
Academic Article
Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo.
Academic Article
Phage display selections for affinity reagents to membrane proteins in nanodiscs.
Academic Article
Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation.
Academic Article
Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation.
Academic Article
A New Versatile Immobilization Tag Based on the Ultra High Affinity and Reversibility of the Calmodulin-Calmodulin Binding Peptide Interaction.
Academic Article
A YidC-like Protein in the Archaeal Plasma Membrane.
Academic Article
A High Through-put Platform for Recombinant Antibodies to Folded Proteins.
Academic Article
Architecture of the fungal nuclear pore inner ring complex.
Academic Article
Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins.
Academic Article
Conformational Chaperones for Structural Studies of Membrane Proteins Using Antibody Phage Display with Nanodiscs.
Academic Article
A polar ring endows improved specificity to an antibody fragment.
Academic Article
Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment.
Academic Article
Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins.
Academic Article
Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.
Academic Article
Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2.
Academic Article
Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Academic Article
An engineered ultra-high affinity Fab-Protein G pair enables a modular antibody platform with multifunctional capability.
Academic Article
Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM.
Academic Article
Structure and drug resistance of the Plasmodium falciparum transporter PfCRT.
Academic Article
Structure and mechanism of the ER-based glucosyltransferase ALG6.
Academic Article
Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
Academic Article
Recognition of an a-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Academic Article
Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.
Academic Article
Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers.
Academic Article
Structural basis of lipopolysaccharide maturation by the O-antigen ligase.
Academic Article
Synthetic Antibodies Detect Distinct Cellular States of Chromosome Passenger Complex Proteins.
Academic Article
Architecture of the cytoplasmic face of the nuclear pore.
Academic Article
A peroxisomal ubiquitin ligase complex forms a retrotranslocation channel.
Academic Article
Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.
Grant
Chaperone Assisted Crystallography
Grant
Chaperone-Enabled studies of epigenetic regulation enzymes
Grant
Energetics of cytokine-induced receptor signaling
Academic Article
Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels.
Academic Article
Characterization of synthetic antigen binding fragments targeting Toc75 for the isolation of TOC in A. thaliana and P. sativum.
Academic Article
Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA.
Academic Article
Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry.
Academic Article
Structure of human drug transporters OATP1B1 and OATP1B3.
Academic Article
Chaperone-assisted cryo-EM structure of P. aeruginosa PhuR reveals molecular basis for heme binding.
Academic Article
Structural and molecular basis of choline uptake into the brain by FLVCR2.
Search Criteria
Antimicrobial
proteins