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One or more keywords matched the following properties of Kossiakoff, Anthony
keywords Membrane Proteins
One or more keywords matched the following items that are connected to Kossiakoff, Anthony
Item TypeName
Concept Bacterial Proteins
Concept Calmodulin-Binding Proteins
Concept Fungal Proteins
Concept Chromosomal Proteins, Non-Histone
Concept Microfilament Proteins
Concept Nerve Tissue Proteins
Concept Plant Proteins
Concept Muscle Proteins
Concept Proteins
Concept Protozoan Proteins
Concept RNA-Binding Proteins
Concept Oncogene Proteins, Viral
Concept Green Fluorescent Proteins
Concept Cell Cycle Proteins
Concept ras GTPase-Activating Proteins
Concept Nuclear Pore Complex Proteins
Concept Arabidopsis Proteins
Concept Saccharomyces cerevisiae Proteins
Concept Recombinant Proteins
Concept Adaptor Proteins, Signal Transducing
Concept Viral Proteins
Concept GTP-Binding Proteins
Concept Antifreeze Proteins
Concept Antimicrobial Cationic Peptides
Concept Mutant Proteins
Concept Escherichia coli Proteins
Concept Carrier Proteins
Concept Neoplasm Proteins
Concept Nuclear Proteins
Concept Recombinant Fusion Proteins
Concept Archaeal Proteins
Concept Membrane Transport Proteins
Concept Maltose-Binding Proteins
Academic Article Variability of conformations at crystal contacts in BPTI represent true low-energy structures: correspondence among lattice packing and molecular dynamics structures.
Academic Article Structural consequences of mutation.
Academic Article Structural effects induced by mutagenesis affected by crystal packing factors: the structure of a 30-51 disulfide mutant of basic pancreatic trypsin inhibitor.
Academic Article Crystallization and preliminary X-ray analysis of a 1:1 complex between a designed monomeric interferon-gamma and its soluble receptor.
Academic Article Crystallization of ovine placental lactogen in a 1:2 complex with the extracellular domain of the rat prolactin receptor.
Academic Article Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor.
Academic Article Biosynthetic phage display: a novel protein engineering tool combining chemical and genetic diversity.
Academic Article Analysis of solvent structure in proteins using neutron D2O-H2O solvent maps: pattern of primary and secondary hydration of trypsin.
Academic Article Solvent structure in crystals of trypsin determined by X-ray and neutron diffraction.
Academic Article The 2.0 A structure of bovine interferon-gamma; assessment of the structural differences between species.
Academic Article Deciphering the role of the electrostatic interactions involving Gly70 in eglin C by total chemical protein synthesis.
Academic Article Crystals of the complex between human growth hormone and the extracellular domain of its receptor.
Academic Article The first semi-synthetic serine protease made by native chemical ligation.
Academic Article The crystal structure of Aq_328 from the hyperthermophilic bacteria Aquifex aeolicus shows an ancestral histone fold.
Academic Article Dissecting the energetics of protein alpha-helix C-cap termination through chemical protein synthesis.
Academic Article X-ray structure of snow flea antifreeze protein determined by racemic crystallization of synthetic protein enantiomers.
Academic Article The 1.38 A crystal structure of DmsD protein from Salmonella typhimurium, a proofreading chaperone on the Tat pathway.
Academic Article The high- and low-affinity receptor binding sites of growth hormone are allosterically coupled.
Academic Article Alternative views of functional protein binding epitopes obtained by combinatorial shotgun scanning mutagenesis.
Academic Article Comprehensive and quantitative mapping of energy landscapes for protein-protein interactions by rapid combinatorial scanning.
Academic Article The role of protein dynamics in increasing binding affinity for an engineered protein-protein interaction established by H/D exchange mass spectrometry.
Academic Article Time-controlled microfluidic seeding in nL-volume droplets to separate nucleation and growth stages of protein crystallization.
Academic Article Exploring the capacity of minimalist protein interfaces: interface energetics and affinity maturation to picomolar KD of a single-domain antibody with a flat paratope.
Academic Article Mechanism of activation gating in the full-length KcsA K+ channel.
Academic Article Intramolecular cooperativity in a protein binding site assessed by combinatorial shotgun scanning mutagenesis.
Academic Article Crystal structure of full-length KcsA in its closed conformation.
Academic Article A method of solvent structure analysis for proteins using D2O-H2O neutron difference maps.
Academic Article X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling.
Academic Article The crystal structure of affinity-matured human growth hormone at 2 A resolution.
Academic Article Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins.
Academic Article Protein dynamics investigated by neutron diffraction.
Academic Article Neutron protein crystallography: advances in methods and applications.
Academic Article Substance P derivatives as versatile tools for specific delivery of various types of biomolecular cargo.
Academic Article Crystal structures of subtilisin BPN' variants containing disulfide bonds and cavities: concerted structural rearrangements induced by mutagenesis.
Academic Article Molecular recognition in biological systems: from activation to inhibition.
Academic Article Effect of protein packing structure on side-chain methyl rotor conformations.
Academic Article Racemic crystallography of synthetic protein enantiomers used to determine the X-ray structure of plectasin by direct methods.
Academic Article The use of neutrons to show how proteins work.
Academic Article Principal determinants leading to transition state formation of a protein-protein complex, orientation trumps side-chain interactions.
Academic Article An engineered substance P variant for receptor-mediated delivery of synthetic antibodies into tumor cells.
Academic Article Characterization of engineered actin binding proteins that control filament assembly and structure.
Academic Article The application of neutron crystallography to the study of dynamic and and hydration properties of proteins.
Academic Article Generating conformation-specific synthetic antibodies to trap proteins in selected functional states.
Academic Article Visualization of arrestin recruitment by a G-protein-coupled receptor.
Academic Article Probing the functions of the paramyxovirus glycoproteins F and HN with a panel of synthetic antibodies.
Academic Article Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments.
Academic Article Nuclear pores. Architecture of the nuclear pore complex coat.
Academic Article Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo.
Academic Article Phage display selections for affinity reagents to membrane proteins in nanodiscs.
Academic Article Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation.
Academic Article Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation.
Academic Article A New Versatile Immobilization Tag Based on the Ultra High Affinity and Reversibility of the Calmodulin-Calmodulin Binding Peptide Interaction.
Academic Article A YidC-like Protein in the Archaeal Plasma Membrane.
Academic Article A High Through-put Platform for Recombinant Antibodies to Folded Proteins.
Academic Article Architecture of the fungal nuclear pore inner ring complex.
Academic Article Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins.
Academic Article Conformational Chaperones for Structural Studies of Membrane Proteins Using Antibody Phage Display with Nanodiscs.
Academic Article A polar ring endows improved specificity to an antibody fragment.
Academic Article Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment.
Academic Article Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins.
Academic Article Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.
Academic Article Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2.
Academic Article Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Academic Article An engineered ultra-high affinity Fab-Protein G pair enables a modular antibody platform with multifunctional capability.
Academic Article Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM.
Academic Article Structure and drug resistance of the Plasmodium falciparum transporter PfCRT.
Academic Article Structure and mechanism of the ER-based glucosyltransferase ALG6.
Academic Article Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
Academic Article Recognition of an a-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Academic Article Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.
Academic Article Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers.
Academic Article Structural basis of lipopolysaccharide maturation by the O-antigen ligase.
Academic Article Synthetic Antibodies Detect Distinct Cellular States of Chromosome Passenger Complex Proteins.
Academic Article Architecture of the cytoplasmic face of the nuclear pore.
Academic Article A peroxisomal ubiquitin ligase complex forms a retrotranslocation channel.
Grant Chaperone Assisted Crystallography
Grant Chaperone-Enabled studies of epigenetic regulation enzymes
Grant Energetics of cytokine-induced receptor signaling
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  • Antimicrobial
  • proteins