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Search Results to Dezheng Huo

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keywords Breast Cancer
overview Dr. Huo’s research interests focus on the genetic, molecular, and environmental factors underlying etiology, prognosis, and treatment of cancers, particularly as they relate to cancer in underserved populations. His research spans across several areas of cancer epidemiology and clinical epidemiology, including: 1. Genetic epidemiology of breast cancer, particular in women of African ancestry with the use of genome-wide association and whole genome sequencing approach. 2. Environmental and lifestyle factors for breast cancer etiology in African women and risk prediction model building, and strategy for cancer screening. 3. Epigenetics and non-coding RNAs, such as microRNAs in relationship to cancer prognosis and survival. 4. Investigation of the utilization and effectiveness of cancer treatment in real world using big data. 5. Prenatal exposure to diethylstilbestrol and clear cell adenocarcinoma of vagina and cervix, as well as other health conditions in later life. 6. Health disparity in breast cancer outcomes in multiethnic patient cohort study with multi-dimensional data.

One or more keywords matched the following items that are connected to Huo, Dezheng

Item TypeName
Concept Breast Neoplasms
Concept Bone Neoplasms
Concept Urinary Bladder Neoplasms
Concept Colonic Neoplasms
Concept Uterine Cervical Neoplasms
Concept Kidney Neoplasms
Concept Neoplasms, Multiple Primary
Concept Neoplasms, Radiation-Induced
Concept Liver Neoplasms
Concept Pancreatic Neoplasms
Concept Ovarian Neoplasms
Concept Lung Neoplasms
Concept Prostatic Neoplasms
Concept Rectal Neoplasms
Concept Head and Neck Neoplasms
Concept Uterine Neoplasms
Concept Urologic Neoplasms
Concept Vaginal Neoplasms
Concept Neoplasms, Second Primary
Concept Mouth Neoplasms
Concept Endometrial Neoplasms
Concept National Cancer Institute (U.S.)
Concept Skin Neoplasms
Concept Colorectal Neoplasms
Concept Thyroid Neoplasms
Concept Hereditary Breast and Ovarian Cancer Syndrome
Concept Early Detection of Cancer
Concept Breast Neoplasms, Male
Concept Hematologic Neoplasms
Concept Brain Neoplasms
Concept Neoplasms
Concept Neoplasms, Basal Cell
Academic Article Carboplatin plus vinorelbine with concomitant radiation therapy in advanced non-small cell lung cancer: a phase I study.
Academic Article Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck.
Academic Article Data management and statistical methods used in the analysis of balanced chromosome abnormalities in therapy-related myelodysplastic syndromes and therapy-related acute leukemia: report from an international workshop.
Academic Article Mitogen-activated protein kinase kinase 4 (MKK4) acts as a metastasis suppressor gene in human ovarian carcinoma.
Academic Article Prognostic factors for survival with gemcitabine plus 5-fluorouracil based regimens for metastatic renal cancer.
Academic Article Strong synergy between mutant ras and HPV16 E6/E7 in the development of primary tumors.
Academic Article A phase I trial of gemcitabine plus cladribine in patients with advanced hematologic malignant diseases.
Academic Article Clinical-cytogenetic associations in 306 patients with therapy-related myelodysplasia and myeloid leukemia: the University of Chicago series.
Academic Article Aminosalicylate therapy in the prevention of dysplasia and colorectal cancer in ulcerative colitis.
Academic Article The p38 kinases MKK4 and MKK6 suppress metastatic colonization in human ovarian carcinoma.
Academic Article Myoid differentiation and prognosis in adult pleomorphic sarcomas of the extremity: an analysis of 92 cases.
Academic Article Dietary fatty acids correlate with prostate cancer biopsy grade and volume in Jamaican men.
Academic Article Parity and breastfeeding are protective against breast cancer in Nigerian women.
Academic Article Suppression of bone density loss and bone turnover in patients with hormone-sensitive prostate cancer and receiving zoledronic acid.
Academic Article Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and breast cancer risk in Africans.
Academic Article c-Jun NH2-terminal kinase activating kinase 1/mitogen-activated protein kinase kinase 4-mediated inhibition of SKOV3ip.1 ovarian cancer metastasis involves growth arrest and p21 up-regulation.
Academic Article Histone deacetylase inhibitor romidepsin has differential activity in core binding factor acute myeloid leukemia.
Academic Article Advances in breast cancer: pathways to personalized medicine.
Academic Article MDM2 SNP309 and TP53 Arg72Pro interact to alter therapy-related acute myeloid leukemia susceptibility.
Academic Article Prediction of BRCA Mutations Using the BRCAPRO Model in Clinic-Based African American, Hispanic, and Other Minority Families in the United States.
Academic Article Zoledronic acid initiated during the first year of androgen deprivation therapy increases bone mineral density in patients with prostate cancer.
Academic Article Outcome after surveillance of low-grade and indefinite dysplasia in patients with ulcerative colitis.
Academic Article A phase II study of sorafenib in advanced uterine carcinoma/carcinosarcoma: a trial of the Chicago, PMH, and California Phase II Consortia.
Academic Article Wnt/beta-catenin pathway activation is enriched in basal-like breast cancers and predicts poor outcome.
Academic Article Phase II trial of adjuvant gemcitabine plus cisplatin-based chemotherapy in patients with locally advanced bladder cancer.
Academic Article Interpretation of genome-wide association study results.
Academic Article Screening RAD51C nucleotide alterations in patients with a family history of breast and ovarian cancer.
Academic Article Proliferating macrophages associated with high grade, hormone receptor negative breast cancer and poor clinical outcome.
Academic Article c-Myc activates BRCA1 gene expression through distal promoter elements in breast cancer cells.
Academic Article High dose cytarabine and mitoxantrone: an effective induction regimen for high-risk acute myeloid leukemia (AML).
Academic Article Lack of association between common single nucleotide polymorphisms in the TERT-CLPTM1L locus and breast cancer in women of African ancestry.
Academic Article Germline mutational analysis of the C19orf62 gene in African-American women with breast cancer.
Academic Article Population differences in breast cancer: survey in indigenous African women reveals over-representation of triple-negative breast cancer.
Academic Article Evaluation of 19 susceptibility loci of breast cancer in women of African ancestry.
Academic Article Cancer death rates for older Asian-Americans: classification by race versus ethnicity.
Academic Article Genetic susceptibility to type 2 diabetes and breast cancer risk in women of European and African ancestry.
Academic Article Recurrent BRCA1 and BRCA2 mutations in breast cancer patients of African ancestry.
Academic Article Novel germline PALB2 truncating mutations in African American breast cancer patients.
Academic Article Squamous cell carcinomas of the skin at ear tag sites in aged FVB/N mice.
Academic Article Basal-like Breast cancer DNA copy number losses identify genes involved in genomic instability, response to therapy, and patient survival.
Academic Article Efficacy and safety of treating T4 oral cavity tumors with primary chemoradiotherapy.
Academic Article Ancestry-shift refinement mapping of the C6orf97-ESR1 breast cancer susceptibility locus.
Academic Article Case-control study of body size and breast cancer risk in Nigerian women.
Academic Article Planned post-chemoradiation neck dissection: significance of radiation dose.
Academic Article Concordance in histological and biological parameters between first and second primary breast cancers.
Academic Article Robust segmentation of mass-lesions in contrast-enhanced dynamic breast MR images.
Academic Article Protective effect of longstanding lactation and reproductive factors: a case-control study in North Tanzania.
Academic Article Population-based patterns and predictors of prostate-specific antigen screening among older men in the United States.
Academic Article Microsatellites in the estrogen receptor (ESR1, ESR2) and androgen receptor (AR) genes and breast cancer risk in African American and Nigerian women.
Academic Article High prevalence of BRCA1 and BRCA2 mutations in unselected Nigerian breast cancer patients.
Academic Article 2008 US Preventive Services Task Force recommendations and prostate cancer screening rates.
Academic Article Up-regulation of MKK4, MKK6 and MKK7 during prostate cancer progression: an important role for SAPK signalling in prostatic neoplasia.
Academic Article Complementary and alternative medicine use among breast cancer survivors.
Academic Article Lifestyle factors and duration of androgen deprivation affect bone mineral density of patients with prostate cancer during first year of therapy.
Academic Article Genetic variation in IGFBP2 and IGFBP5 is associated with breast cancer in populations of African descent.
Academic Article Evidence for an ancient BRCA1 mutation in breast cancer patients of Yoruban ancestry.
Academic Article CpG island methylation affects accessibility of the proximal BRCA1 promoter to transcription factors.
Academic Article Searching for large genomic rearrangements of the BRCA1 gene in a Nigerian population.
Academic Article A signature of balancing selection in the region upstream to the human UGT2B4 gene and implications for breast cancer risk.
Academic Article Molecular analysis of colorectal tumors within a diverse patient cohort at a single institution.
Academic Article Increased expression of S100A6 is associated with decreased metastasis and inhibition of cell migration and anchorage independent growth in human osteosarcoma.
Academic Article Phase II trial of gefitinib 250 mg daily in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck.
Academic Article Genetic testing in diverse populations: are researchers doing enough to get out the correct message?
Academic Article Association between colorectal cancer and urologic cancers.
Academic Article Association of colorectal cancer and prostate cancer and impact of radiation therapy.
Academic Article Lack of association between common UGT2B nonsynonymous single-nucleotide polymorphisms and breast cancer in populations of African ancestry.
Academic Article Phase II trial of temsirolimus in patients with metastatic breast cancer.
Academic Article Body fat distribution and breast cancer risk: findings from the Nigerian breast cancer study.
Academic Article Fine mapping of breast cancer genome-wide association studies loci in women of African ancestry identifies novel susceptibility markers.
Academic Article Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.
Academic Article A genome-wide association study of breast cancer in women of African ancestry.
Academic Article A trend analysis of breast cancer incidence rates in the United States from 2000 to 2009 shows a recent increase.
Academic Article MicroRNA-30c targets cytoskeleton genes involved in breast cancer cell invasion.
Academic Article Incidence rate of breast cancer in young women.
Academic Article A meta-analysis of male breast cancer in Africa.
Academic Article MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11.
Academic Article Expression and sub-cellular localization of an epigenetic regulator, co-activator arginine methyltransferase 1 (CARM1), is associated with specific breast cancer subtypes and ethnicity.
Academic Article Hormone replacement therapy and breast cancer: heterogeneous risks by race, weight, and breast density.
Academic Article The role of statins for primary prevention in non-elderly colorectal cancer patients.
Academic Article Inherited predisposition to breast cancer among African American women.
Academic Article Alcohol consumption and breast cancer risk among women in three sub-Saharan African countries.
Academic Article An epidemiologic investigation of physical activity and breast cancer risk in Africa.
Academic Article Risk factors for pregnancy-associated breast cancer: a report from the Nigerian Breast Cancer Study.
Academic Article Axillary surgery among estrogen receptor positive women 70 years of age or older with clinical stage I breast cancer, 2004-2010: a report from the National Cancer Data Base.
Academic Article Factors associated with compliance to adjuvant hormone therapy in Black and White women with breast cancer.
Academic Article Heterogeneity in hormone-receptor status and survival outcomes among women with synchronous and metachronous bilateral breast cancers.
Academic Article Inflammation is an independent risk factor for colonic neoplasia in patients with ulcerative colitis: a case-control study.
Academic Article Contralateral prophylactic mastectomy and survival: report from the National Cancer Data Base, 1998-2002.
Academic Article Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.
Academic Article National trends in prostate cancer screening among older American men with limited 9-year life expectancies: evidence of an increased need for shared decision making.
Academic Article Discordance in hormone receptor status among primary, metastatic, and second primary breast cancers: biological difference or misclassification?
Academic Article Pilot study demonstrating potential association between breast cancer image-based risk phenotypes and genomic biomarkers.
Academic Article Utilization of accelerated partial breast irradiation for ductal carcinoma in situ, 2003-2011: report from the national cancer database.
Academic Article A comprehensive examination of breast cancer risk loci in African American women.
Academic Article Accelerated partial-breast irradiation versus whole-breast irradiation for early-stage breast cancer patients undergoing breast conservation, 2003-2010: a report from the national cancer data base.
Academic Article Use of Web-based training for quality improvement between a field immunohistochemistry laboratory in Nigeria and its United States-based partner institution.
Academic Article Prevention of colorectal cancer and dietary management.
Academic Article National Prostate Cancer Screening Rates After the 2012 US Preventive Services Task Force Recommendation Discouraging Prostate-Specific Antigen-Based Screening.
Academic Article Use of Postmastectomy Radiotherapy and Survival Rates for Breast Cancer Patients with T1-T2 and One to Three Positive Lymph Nodes.
Academic Article Increased utilization of postmastectomy radiotherapy in the United States from 2003 to 2011 in patients with one to three tumor positive nodes.
Academic Article Inherited mutations in cancer susceptibility genes are common among survivors of breast cancer who develop therapy-related leukemia.
Academic Article The Thr300Ala variant in ATG16L1 is associated with improved survival in human colorectal cancer and enhanced production of type I interferon.
Academic Article Breast cancer risk after full-term pregnancies among African women from Nigeria, Cameroon, and Uganda.
Academic Article ß-catenin regulates c-Myc and CDKN1A expression in breast cancer cells.
Academic Article Genetic anticipation in BRCA1/BRCA2 families after controlling for ascertainment bias and cohort effect.
Academic Article Bayesian adjustment for the misclassification in both dependent and independent variables with application to a breast cancer study.
Academic Article Genetic variants in microRNA and microRNA biogenesis pathway genes and breast cancer risk among women of African ancestry.
Academic Article Effect of BRCA germline mutations on breast cancer prognosis: A systematic review and meta-analysis.
Academic Article miR-206 Inhibits Stemness and Metastasis of Breast Cancer by Targeting MKL1/IL11 Pathway.
Academic Article Genetic and Epigenetic Regulation of TOX3 Expression in Breast Cancer.
Academic Article Identification of a circulating microRNA signature to distinguish recurrence in breast cancer patients.
Academic Article Evaluation of the Quality of Adjuvant Endocrine Therapy Delivery for Breast Cancer Care in the United States.
Academic Article Genome-wide association studies in women of African ancestry identified 3q26.21 as a novel susceptibility locus for oestrogen receptor negative breast cancer.
Academic Article Utilization trend and regimens of hypofractionated whole breast radiation therapy in the United States.
Academic Article Characterizing Genetic Susceptibility to Breast Cancer in Women of African Ancestry.
Academic Article Limited influence of germline genetic variation on all-cause mortality in women with early onset breast cancer: evidence from gene-based tests, single-marker regression, and whole-genome prediction.
Academic Article Association of breast cancer risk and the mTOR pathway in women of African ancestry in 'The Root' Consortium.
Academic Article Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas.
Academic Article A functionally significant SNP in TP53 and breast cancer risk in African-American women.
Academic Article A Tale of Two Cancers: Traveling to Treat Pancreatic and Thyroid Cancer.
Academic Article Incidence rates and risks of diethylstilbestrol-related clear-cell adenocarcinoma of the vagina and cervix: Update after 40-year follow-up.
Academic Article Genetic variants demonstrating flip-flop phenomenon and breast cancer risk prediction among women of African ancestry.
Academic Article Assessment of peri-polyp biopsy specimens of flat mucosa in patients with inflammatory bowel disease.
Academic Article Inherited Breast Cancer in Nigerian Women.
Academic Article De novo metastasis in breast cancer: occurrence and overall survival stratified by molecular subtype.
Academic Article Genetic variation in the vitamin D related pathway and breast cancer risk in women of African ancestry in the root consortium.
Academic Article Community clinical practice patterns and mortality in patients with intermediate oncotype DX recurrence scores: Who benefits from chemotherapy?
Academic Article Prenatal diethylstilbestrol exposure and cancer risk in women.
Academic Article Reported Biologic Differences in Breast Cancer by Race Due to Disparities in Screening-Reply.
Academic Article Genetic variation in the Hippo pathway and breast cancer risk in women of African ancestry.
Academic Article A meta-analysis approach with filtering for identifying gene-level gene-environment interactions.
Academic Article Pilot Survey of Breast Cancer Management in Sub-Saharan Africa.
Academic Article Frequency of Germline Mutations in Cancer Susceptibility Genes in Malignant Mesothelioma.
Academic Article Association of Pancreatic Cancer Susceptibility Variants with Risk of Breast Cancer in Women of European and African Ancestry.
Academic Article Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features.
Academic Article Germline Variation and Breast Cancer Incidence: A Gene-Based Association Study and Whole-Genome Prediction of Early-Onset Breast Cancer.
Academic Article Intensive Surveillance with Biannual Dynamic Contrast-Enhanced Magnetic Resonance Imaging Downstages Breast Cancer in BRCA1 Mutation Carriers.
Academic Article Racial disparities in omission of oncotype DX but no racial disparities in chemotherapy receipt following completed oncotype DX test results.
Academic Article Follow-up of Patients with Clear-Cell Adenocarcinoma of the Vagina and Cervix.
Academic Article Trans-ethnic predicted expression genome-wide association analysis identifies a gene for estrogen receptor-negative breast cancer.
Academic Article Development of a Breast Cancer Risk Prediction Model for Women in Nigeria.
Academic Article Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study.
Academic Article Reproductive and hormone-related outcomes in women whose mothers were exposed in utero to diethylstilbestrol (DES): A report from the US National Cancer Institute DES Third Generation Study.
Academic Article Author Correction: Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features.
Academic Article Identification of novel common breast cancer risk variants at the 6q25 locus among Latinas.
Academic Article The association between weight at birth and breast cancer risk revisited using Mendelian randomisation.
Academic Article Body mass index and the association between low-density lipoprotein cholesterol as predicted by HMGCR genetic variants and breast cancer risk.
Academic Article Germline variants and somatic mutation signatures of breast cancer across populations of African and European ancestry in the US and Nigeria.
Academic Article Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers.
Academic Article Hematologic toxicity in BRCA1 and BRCA2 mutation carriers during chemotherapy: A retrospective matched cohort study.
Academic Article Two truncating variants in FANCC and breast cancer risk.
Academic Article Soy intake and breast cancer risk: a prospective study of 300,000 Chinese women and a dose-response meta-analysis.
Academic Article Prevalence of Inherited Mutations in Breast Cancer Predisposition Genes among Women in Uganda and Cameroon.
Award or Honor Receipt Runner-up in the Up For A Challenge – Stimulating Innovation in Breast Cancer Genetic Epidemiology
Award or Honor Receipt Breast Cancer Research Program study section
Award or Honor Receipt Breast Cancer Research Program study section
Award or Honor Receipt Breast Cancer Research Program study section
Academic Article Clinical evaluation of germline polymorphisms associated with capecitabine toxicity in breast cancer: TBCRC-015.
Academic Article Propensity score analysis of the prognostic value of genomic assays for breast cancer in diverse populations using the National Cancer Data Base.
Academic Article Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk.
Academic Article Circulating Insulin-Like Growth Factor-1 and Risk of Total and 19 Site-Specific Cancers: Cohort Study Analyses from the UK Biobank.
Academic Article Racial disparities in survival outcomes among breast cancer patients by molecular subtypes.

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