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Huo, Dezheng
One or more keywords matched the following properties of Huo, Dezheng
PropertyValue
keywords Breast Cancer
overview Dr. Huo’s research interests focus on the genetic, molecular, and environmental factors underlying etiology, prognosis, and treatment of cancers, particularly as they relate to cancer in underserved populations. His research spans across several areas of cancer epidemiology and clinical epidemiology, including: 1. Genetic epidemiology of breast cancer, particular in women of African ancestry with the use of genome-wide association and whole genome sequencing approach. 2. Environmental and lifestyle factors for breast cancer etiology in African women and risk prediction model building, and strategy for cancer screening. 3. Health disparity in breast cancer outcomes in multiethnic patient cohort study with multi-dimensional data. 4. Investigation of the utilization and effectiveness of cancer treatment in real world using Big data. 5. Prenatal exposure to diethylstilbestrol and clear cell adenocarcinoma of vagina and cervix, as well as other health conditions in later life. 6. Epigenetics and non-coding RNAs, such as microRNAs in relationship to cancer prognosis and survival.
One or more keywords matched the following items that are connected to Huo, Dezheng
Item TypeName
Concept Breast Neoplasms
Concept Breast Neoplasms, Male
Academic Article Parity and breastfeeding are protective against breast cancer in Nigerian women.
Academic Article Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and breast cancer risk in Africans.
Academic Article Advances in breast cancer: pathways to personalized medicine.
Academic Article Prediction of BRCA Mutations Using the BRCAPRO Model in Clinic-Based African American, Hispanic, and Other Minority Families in the United States.
Academic Article Wnt/beta-catenin pathway activation is enriched in basal-like breast cancers and predicts poor outcome.
Academic Article Screening RAD51C nucleotide alterations in patients with a family history of breast and ovarian cancer.
Academic Article Proliferating macrophages associated with high grade, hormone receptor negative breast cancer and poor clinical outcome.
Academic Article c-Myc activates BRCA1 gene expression through distal promoter elements in breast cancer cells.
Academic Article Lack of association between common single nucleotide polymorphisms in the TERT-CLPTM1L locus and breast cancer in women of African ancestry.
Academic Article Germline mutational analysis of the C19orf62 gene in African-American women with breast cancer.
Academic Article Population differences in breast cancer: survey in indigenous African women reveals over-representation of triple-negative breast cancer.
Academic Article Evaluation of 19 susceptibility loci of breast cancer in women of African ancestry.
Academic Article Genetic susceptibility to type 2 diabetes and breast cancer risk in women of European and African ancestry.
Academic Article Recurrent BRCA1 and BRCA2 mutations in breast cancer patients of African ancestry.
Academic Article Novel germline PALB2 truncating mutations in African American breast cancer patients.
Academic Article Basal-like Breast cancer DNA copy number losses identify genes involved in genomic instability, response to therapy, and patient survival.
Academic Article Ancestry-shift refinement mapping of the C6orf97-ESR1 breast cancer susceptibility locus.
Academic Article Case-control study of body size and breast cancer risk in Nigerian women.
Academic Article Concordance in histological and biological parameters between first and second primary breast cancers.
Academic Article Robust segmentation of mass-lesions in contrast-enhanced dynamic breast MR images.
Academic Article Protective effect of longstanding lactation and reproductive factors: a case-control study in North Tanzania.
Academic Article Microsatellites in the estrogen receptor (ESR1, ESR2) and androgen receptor (AR) genes and breast cancer risk in African American and Nigerian women.
Academic Article High prevalence of BRCA1 and BRCA2 mutations in unselected Nigerian breast cancer patients.
Academic Article Complementary and alternative medicine use among breast cancer survivors.
Academic Article Genetic variation in IGFBP2 and IGFBP5 is associated with breast cancer in populations of African descent.
Academic Article Evidence for an ancient BRCA1 mutation in breast cancer patients of Yoruban ancestry.
Academic Article CpG island methylation affects accessibility of the proximal BRCA1 promoter to transcription factors.
Academic Article Searching for large genomic rearrangements of the BRCA1 gene in a Nigerian population.
Academic Article A signature of balancing selection in the region upstream to the human UGT2B4 gene and implications for breast cancer risk.
Academic Article Genetic testing in diverse populations: are researchers doing enough to get out the correct message?
Academic Article Lack of association between common UGT2B nonsynonymous single-nucleotide polymorphisms and breast cancer in populations of African ancestry.
Academic Article Phase II trial of temsirolimus in patients with metastatic breast cancer.
Academic Article Body fat distribution and breast cancer risk: findings from the Nigerian breast cancer study.
Academic Article Fine mapping of breast cancer genome-wide association studies loci in women of African ancestry identifies novel susceptibility markers.
Academic Article Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.
Academic Article A genome-wide association study of breast cancer in women of African ancestry.
Academic Article A trend analysis of breast cancer incidence rates in the United States from 2000 to 2009 shows a recent increase.
Academic Article MicroRNA-30c targets cytoskeleton genes involved in breast cancer cell invasion.
Academic Article Incidence rate of breast cancer in young women.
Academic Article A meta-analysis of male breast cancer in Africa.
Academic Article MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11.
Academic Article Expression and sub-cellular localization of an epigenetic regulator, co-activator arginine methyltransferase 1 (CARM1), is associated with specific breast cancer subtypes and ethnicity.
Academic Article Hormone replacement therapy and breast cancer: heterogeneous risks by race, weight, and breast density.
Academic Article Inherited predisposition to breast cancer among African American women.
Academic Article Alcohol consumption and breast cancer risk among women in three sub-Saharan African countries.
Academic Article An epidemiologic investigation of physical activity and breast cancer risk in Africa.
Academic Article Risk factors for pregnancy-associated breast cancer: a report from the Nigerian Breast Cancer Study.
Academic Article Axillary surgery among estrogen receptor positive women 70 years of age or older with clinical stage I breast cancer, 2004-2010: a report from the National Cancer Data Base.
Academic Article Factors associated with compliance to adjuvant hormone therapy in Black and White women with breast cancer.
Academic Article Heterogeneity in hormone-receptor status and survival outcomes among women with synchronous and metachronous bilateral breast cancers.
Academic Article Contralateral prophylactic mastectomy and survival: report from the National Cancer Data Base, 1998-2002.
Academic Article Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.
Academic Article Discordance in hormone receptor status among primary, metastatic, and second primary breast cancers: biological difference or misclassification?
Academic Article Pilot study demonstrating potential association between breast cancer image-based risk phenotypes and genomic biomarkers.
Academic Article Utilization of accelerated partial breast irradiation for ductal carcinoma in situ, 2003-2011: report from the national cancer database.
Academic Article A comprehensive examination of breast cancer risk loci in African American women.
Academic Article Accelerated partial-breast irradiation versus whole-breast irradiation for early-stage breast cancer patients undergoing breast conservation, 2003-2010: a report from the national cancer data base.
Academic Article Use of Web-based training for quality improvement between a field immunohistochemistry laboratory in Nigeria and its United States-based partner institution.
Academic Article Use of Postmastectomy Radiotherapy and Survival Rates for Breast Cancer Patients with T1-T2 and One to Three Positive Lymph Nodes.
Academic Article Increased utilization of postmastectomy radiotherapy in the United States from 2003 to 2011 in patients with one to three tumor positive nodes.
Academic Article Inherited mutations in cancer susceptibility genes are common among survivors of breast cancer who develop therapy-related leukemia.
Academic Article Breast cancer risk after full-term pregnancies among African women from Nigeria, Cameroon, and Uganda.
Academic Article ß-catenin regulates c-Myc and CDKN1A expression in breast cancer cells.
Academic Article Genetic anticipation in BRCA1/BRCA2 families after controlling for ascertainment bias and cohort effect.
Academic Article Bayesian adjustment for the misclassification in both dependent and independent variables with application to a breast cancer study.
Academic Article Genetic variants in microRNA and microRNA biogenesis pathway genes and breast cancer risk among women of African ancestry.
Academic Article Effect of BRCA germline mutations on breast cancer prognosis: A systematic review and meta-analysis.
Academic Article miR-206 Inhibits Stemness and Metastasis of Breast Cancer by Targeting MKL1/IL11 Pathway.
Academic Article Genetic and Epigenetic Regulation of TOX3 Expression in Breast Cancer.
Academic Article Identification of a circulating microRNA signature to distinguish recurrence in breast cancer patients.
Academic Article Evaluation of the Quality of Adjuvant Endocrine Therapy Delivery for Breast Cancer Care in the United States.
Academic Article Genome-wide association studies in women of African ancestry identified 3q26.21 as a novel susceptibility locus for oestrogen receptor negative breast cancer.
Academic Article Utilization trend and regimens of hypofractionated whole breast radiation therapy in the United States.
Academic Article Characterizing Genetic Susceptibility to Breast Cancer in Women of African Ancestry.
Academic Article Limited influence of germline genetic variation on all-cause mortality in women with early onset breast cancer: evidence from gene-based tests, single-marker regression, and whole-genome prediction.
Academic Article Association of breast cancer risk and the mTOR pathway in women of African ancestry in 'The Root' Consortium.
Academic Article Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas.
Academic Article A functionally significant SNP in TP53 and breast cancer risk in African-American women.
Academic Article Genetic variants demonstrating flip-flop phenomenon and breast cancer risk prediction among women of African ancestry.
Academic Article Inherited Breast Cancer in Nigerian Women.
Academic Article De novo metastasis in breast cancer: occurrence and overall survival stratified by molecular subtype.
Academic Article Genetic variation in the vitamin D related pathway and breast cancer risk in women of African ancestry in the root consortium.
Academic Article Community clinical practice patterns and mortality in patients with intermediate oncotype DX recurrence scores: Who benefits from chemotherapy?
Academic Article Prenatal diethylstilbestrol exposure and cancer risk in women.
Academic Article Reported Biologic Differences in Breast Cancer by Race Due to Disparities in Screening-Reply.
Academic Article Genetic variation in the Hippo pathway and breast cancer risk in women of African ancestry.
Academic Article A meta-analysis approach with filtering for identifying gene-level gene-environment interactions.
Academic Article Pilot Survey of Breast Cancer Management in Sub-Saharan Africa.
Academic Article Association of Pancreatic Cancer Susceptibility Variants with Risk of Breast Cancer in Women of European and African Ancestry.
Academic Article Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features.
Academic Article Germline Variation and Breast Cancer Incidence: A Gene-Based Association Study and Whole-Genome Prediction of Early-Onset Breast Cancer.
Academic Article Intensive Surveillance with Biannual Dynamic Contrast-Enhanced Magnetic Resonance Imaging Downstages Breast Cancer in BRCA1 Mutation Carriers.
Academic Article Racial disparities in omission of oncotype DX but no racial disparities in chemotherapy receipt following completed oncotype DX test results.
Academic Article Trans-ethnic predicted expression genome-wide association analysis identifies a gene for estrogen receptor-negative breast cancer.
Academic Article Development of a Breast Cancer Risk Prediction Model for Women in Nigeria.
Academic Article Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study.
Academic Article Author Correction: Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features.
Academic Article Identification of novel common breast cancer risk variants at the 6q25 locus among Latinas.
Academic Article The association between weight at birth and breast cancer risk revisited using Mendelian randomisation.
Academic Article Body mass index and the association between low-density lipoprotein cholesterol as predicted by HMGCR genetic variants and breast cancer risk.
Grant UChicago Interdisciplinary Cancer Health Disparities SPORE
Academic Article Germline variants and somatic mutation signatures of breast cancer across populations of African and European ancestry in the US and Nigeria.
Academic Article Hematologic toxicity in BRCA1 and BRCA2 mutation carriers during chemotherapy: A retrospective matched cohort study.
Academic Article Two truncating variants in FANCC and breast cancer risk.
Academic Article Soy intake and breast cancer risk: a prospective study of 300,000 Chinese women and a dose-response meta-analysis.
Academic Article Prevalence of Inherited Mutations in Breast Cancer Predisposition Genes among Women in Uganda and Cameroon.
Award or Honor Receipt Runner-up in the Up For A Challenge – Stimulating Innovation in Breast Cancer Genetic Epidemiology
Award or Honor Receipt Breast Cancer Research Program study section
Award or Honor Receipt Breast Cancer Research Program study section
Award or Honor Receipt Breast Cancer Research Program study section
Academic Article Clinical evaluation of germline polymorphisms associated with capecitabine toxicity in breast cancer: TBCRC-015.
Academic Article Propensity score analysis of the prognostic value of genomic assays for breast cancer in diverse populations using the National Cancer Data Base.
Academic Article Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk.
Academic Article Racial disparities in survival outcomes among breast cancer patients by molecular subtypes.
Academic Article Impact of post-diagnosis weight change on survival outcomes in Black and White breast cancer patients.
Academic Article Evaluating Polygenic Risk Scores for Breast Cancer in Women of African Ancestry.
Academic Article Development and external validation of a breast cancer absolute risk prediction model in Chinese population.
Academic Article Instrumental variable approach for estimating a causal hazard ratio: application to the effect of postmastectomy radiotherapy on breast cancer patients.
Academic Article Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women.
Academic Article Has Hypofractionated Whole-Breast Radiation Therapy Become the Standard of Care in the United States? An Updated Report from National Cancer Database.
Academic Article The impact of coronavirus disease 2019 on the quality of life and treatment disruption of patients with breast cancer in a multiethnic cohort.
Academic Article Hypofractionated Radiation Therapy for Breast Cancer: Financial Risk and Expenditures in the United States, 2008 to 2017.
Academic Article Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes.
Academic Article Assessment of Breast Cancer Management in Sub-Saharan Africa.
Academic Article Differences in somatic TP53 mutation type in breast tumors by race and receptor status.
Academic Article Polygenic risk scores for prediction of breast cancer risk in women of African ancestry: a cross-ancestry approach.
Academic Article Validation of the Nigerian Breast Cancer Study Model for Predicting Individual Breast Cancer Risk in Cameroon and Uganda.
Academic Article Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry.
Academic Article An enhancer variant associated with breast cancer susceptibility in Black women regulates TNFSF10 expression and antitumor immunity in triple-negative breast cancer.
Academic Article The optimization of postoperative radiotherapy in de novo stage IV breast cancer: evidence from real-world data to personalize treatment decisions.
Academic Article Clinicopathologic Characteristics and Prognosis of ERBB2-Low Breast Cancer Among Patients in the National Cancer Database.
Academic Article A metabolome-wide case-control study of african american breast cancer patients.
Concept Triple Negative Breast Neoplasms
Grant MicroRNAs As Novel Biomarkers For Detection of Triple-Negative Breast Cancer
Grant Replication Study of Breast Cancer Susceptibility Genes in Blacks
Grant Integrative Genetic Epidemiologic Study of Breast Cancer Subtypes
Grant Identifying Barriers for Slow Update of Effective Radiotherapy Method for Cancer
Grant Genetic risk scores modeling admixture linkage disequilibrium for breast cancer in African Americans
Grant Polygenic Risk Prediction of Breast Cancer for Women of African Descent
Grant Etiology and Genomics of Breast Cancer Progression in Women of African Ancestry
Grant Transcriptome-wide association studies and genetic risk prediction for breast cancer integrating RNA splicing and gene expression from multiple tissues
Grant Using Genomics to Reduce Breast Cancer Disparities in the African Diaspora
Academic Article Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores.
Academic Article The Impact of Race and Age on Response to Neoadjuvant Therapy and Long-Term Outcomes in Black and White Women with Early-Stage Breast Cancer.
Academic Article Response to Treatment, Racial and Ethnic Disparity, and Survival in Patients With Breast Cancer Undergoing Neoadjuvant Chemotherapy in the US.
Academic Article Evaluation of multigene assays as predictors for response to neoadjuvant chemotherapy in early-stage breast cancer patients.
Academic Article A joint transcriptome-wide association study across multiple tissues identifies candidate breast cancer susceptibility genes.
Academic Article The impact of race and age on response to neoadjuvant therapy and long-term outcomes in Black and White women with early-stage breast cancer.
Academic Article Racial Disparities in Pathological Complete Response Among Patients Receiving Neoadjuvant Chemotherapy for Early-Stage Breast Cancer.
Academic Article Integration of clinical features and deep learning on pathology for the prediction of breast cancer recurrence assays and risk of recurrence.
Academic Article Molecular profiling of a real-world breast cancer cohort with genetically inferred ancestries reveals actionable tumor biology differences between European ancestry and African ancestry patient populations.
Academic Article Demographic and Clinical Characteristics Associated With Familiarity, Interest, and Use of Integrative Therapies Among Patients With Breast Cancer.
Academic Article Classification of Breast Cancer According to ERBB2 Immunohistochemistry Scores-Reply.
Academic Article Benign breast disease and breast cancer risk in African women: A case-control study.
Academic Article Stress, Isolation, and Sleep Quality among Breast Cancer Survivors throughout the COVID-19 Pandemic: A Longitudinal Study in a Multi-Ethnic Cohort.
Academic Article Racial/Ethnic Disparities in Telemedicine Utilization and Satisfaction Among Breast Cancer Patients During the COVID-19 Pandemic: A Mixed-Methods Analysis.
Academic Article Unawareness of breast cancer family history among African women.
Academic Article External Evaluation of a Mammography-based Deep Learning Model for Predicting Breast Cancer in an Ethnically Diverse Population.
Academic Article Validation of the RSClin risk calculator in the National Cancer Data Base.
Academic Article Addition of polygenic risk score to a risk calculator for prediction of breast cancer in US Black women.
Academic Article Benign breast disease and breast cancer risk in African women: a case-control study.
Academic Article Novel breast cancer susceptibility loci under linkage peaks identified in African ancestry consortia.
Academic Article Palliative Care Use Trends, Racial/Ethnic Disparities, and Overall Survival Differences Among Patients With Metastatic Breast Cancer.
Academic Article Racial differences in familiarity, interest, and use of integrative medicine among patients with breast cancer.
Academic Article Multi-tissue transcriptome-wide association studies identified 235 genes for intrinsic subtypes of breast cancer.
Academic Article Expression- and splicing-based multi-tissue transcriptome-wide association studies identified multiple genes for breast cancer by estrogen-receptor status.
Academic Article Addressing Social Determinants in the Era of Precision Medicine in Breast Cancer: Is It Sufficient to Reduce Disparities?
Academic Article Using genome and transcriptome data from African-ancestry female participants to identify putative breast cancer susceptibility genes.
Academic Article Declination of Treatment, Racial and Ethnic Disparity, and Overall Survival in US Patients With Breast Cancer.
Academic Article Racial differences in familiarity, interest, and use of integrative medicine among patients with breast cancer.
Academic Article A multi-tissue, splicing-based joint transcriptome-wide association study identifies susceptibility genes for breast cancer.
Academic Article Genome-wide association analyses of breast cancer in women of African ancestry identify new susceptibility loci and improve risk prediction.
Academic Article Case-Case Genome-Wide Analyses Identify Subtype-Informative Variants That Confer Risk for Breast Cancer.
Academic Article Association of ESR1 Germline Variants with TP53 Somatic Variants in Breast Tumors in a Genome-wide Study.
Academic Article Geographic and Physician-Level Variation in the Use of Hypofractionated Radiation Therapy for Breast Cancer in the U.S.: A Cross-Classified Multilevel Analysis.
Academic Article Increase in Hypofractionated Radiation Therapy Among Patients with Invasive Breast Cancer or Ductal Carcinoma In Situ: Who is Left Behind?
Academic Article Development and validation of a clinical breast cancer tool for accurate prediction of recurrence.
Academic Article Assessing the Relationship Between Neighborhood Socioeconomic Disadvantage and Telemedicine Use Among Patients With Breast Cancer and Examining Differential Provisions of Oncology Services Between Telehealth and In-Person Visits: Quantitative Study.
Academic Article Expenditures and Use of Hypofractionated Radiation Therapy Treating Breast Cancer Among Medicare Advantage Enrollees, 2009 to 2017.
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