Item Type | Name |
Concept
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Head and Neck Neoplasms
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Academic Article
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Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck.
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Academic Article
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A phase II trial of perifosine, an oral alkylphospholipid, in recurrent or metastatic head and neck cancer.
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Academic Article
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Protein kinase C zeta mediates epidermal growth factor-induced growth of head and neck tumor cells by regulating mitogen-activated protein kinase.
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Academic Article
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Phase I trial of tirapazamine, cisplatin, and concurrent accelerated boost reirradiation in patients with recurrent head and neck cancer.
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Academic Article
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A phase I trial of docetaxel based induction and concomitant chemotherapy in patients with locally advanced head and neck cancer.
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Academic Article
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The expanding role of systemic therapy in head and neck cancer.
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Academic Article
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The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma.
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Academic Article
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A feed-forward loop involving protein kinase Calpha and microRNAs regulates tumor cell cycle.
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Academic Article
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Phase I study of bevacizumab added to fluorouracil- and hydroxyurea-based concomitant chemoradiotherapy for poor-prognosis head and neck cancer.
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Academic Article
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Characteristics associated with swallowing changes after concurrent chemotherapy and radiotherapy in patients with head and neck cancer.
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Academic Article
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Response of some head and neck cancers to epidermal growth factor receptor tyrosine kinase inhibitors may be linked to mutation of ERBB2 rather than EGFR.
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Academic Article
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High survival and organ function rates after primary chemoradiotherapy for intermediate-stage squamous cell carcinoma of the head and neck treated in a multicenter phase II trial.
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Academic Article
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Erlotinib and bevacizumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck: a phase I/II study.
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Academic Article
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Personalizing cancer care: updates on head and neck cancer.
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Academic Article
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Epidermal growth factor receptor inhibitor gefitinib added to chemoradiotherapy in locally advanced head and neck cancer.
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Academic Article
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[18F]Fluorodeoxyglucose positron emission tomography in the initial staging of squamous cell carcinoma of the head and neck: promise, evidence, and reality.
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Academic Article
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Factors associated with long-term speech and swallowing outcomes after chemoradiotherapy for locoregionally advanced head and neck cancer.
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Academic Article
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Prior chemoradiotherapy adversely impacts outcomes of recurrent and second primary head and neck cancer treated with concurrent chemotherapy and reirradiation.
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Academic Article
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A randomized phase II study of 5-fluorouracil, hydroxyurea, and twice-daily radiotherapy compared with bevacizumab plus 5-fluorouracil, hydroxyurea, and twice-daily radiotherapy for intermediate-stage and T4N0-1 head and neck cancers.
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Academic Article
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Airway management before chemoradiation for advanced head and neck cancer.
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Academic Article
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Phase II trial of pemetrexed-based induction chemotherapy followed by concomitant chemoradiotherapy in previously irradiated patients with squamous cell carcinoma of the head and neck.
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Academic Article
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Phase II study of sunitinib malate in head and neck squamous cell carcinoma.
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Academic Article
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Free-flap reconstruction in the doubly irradiated patient population.
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Academic Article
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Predictors of competing mortality in advanced head and neck cancer.
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Academic Article
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Planned post-chemoradiation neck dissection: significance of radiation dose.
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Academic Article
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A phase II study of lapatinib in recurrent/metastatic squamous cell carcinoma of the head and neck.
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Academic Article
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Efficacy of the multi-kinase inhibitor enzastaurin is dependent on cellular signaling context.
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Academic Article
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Single sample expression-anchored mechanisms predict survival in head and neck cancer.
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Academic Article
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Factors associated with clinical benefit from epidermal growth factor receptor inhibitors in recurrent and metastatic squamous cell carcinoma of the head and neck.
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Academic Article
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A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
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Academic Article
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Phase II study of gefitinib adaptive dose escalation to skin toxicity in recurrent or metastatic squamous cell carcinoma of the head and neck.
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Academic Article
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Phase II trial of gefitinib 250 mg daily in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck.
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Academic Article
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A randomized validation study comparing embedded versus extracted FACT Head and Neck Symptom Index scores.
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Academic Article
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Induction chemotherapy and concurrent chemoradiotherapy for locoregionally advanced head and neck cancer: a multi-institutional phase II trial investigating three radiotherapy dose levels.
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Academic Article
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Adjuvant chemotherapy prior to postoperative concurrent chemoradiotherapy for locoregionally advanced head and neck cancer.
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Academic Article
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Role of molecular markers in the management of head and neck cancers.
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Academic Article
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Effect of complementary pathway blockade on efficacy of combination enzastaurin and rapamycin.
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Academic Article
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Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers.
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Academic Article
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Quality of life scores as prognostic factors of overall survival in advanced head and neck cancer: analysis of a phase III randomized trial of pemetrexed plus cisplatin versus cisplatin monotherapy.
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Academic Article
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Introduction: head and neck cancer.
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Academic Article
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Surrogate endpoints in head and neck cancer.
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Academic Article
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A disturbance in the force--mitochondrial mutations in squamous cell carcinoma of the head and neck.
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Academic Article
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Design of Phase II cancer trials for evaluation of cytostatic/cytotoxic agents.
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Academic Article
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Detection of tumor epidermal growth factor receptor pathway dependence by serum mass spectrometry in cancer patients.
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Academic Article
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Current treatment options for metastatic head and neck cancer.
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Academic Article
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Novel therapeutic targets in squamous cell carcinoma of the head and neck.
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Academic Article
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State-of-the-art management of locally advanced head and neck cancer.
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Academic Article
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Mechanisms of resistance to EGFR inhibitors in head and neck cancer.
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Academic Article
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A phase I dose escalation study of Ad GV.EGR.TNF.11D (TNFerade™ Biologic) with concurrent chemoradiotherapy in patients with recurrent head and neck cancer undergoing reirradiation.
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Academic Article
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Pharmacoeconomic issues in head and neck oncology.
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Academic Article
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Treatment of squamous cell carcinoma of the head and neck in the metastatic and refractory settings: advances in chemotherapy and the emergence of small molecule epidermal growth factor receptor kinase inhibitors.
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Academic Article
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Targeting angiogenesis in head and neck cancer.
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Academic Article
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New strategies in head and neck cancer: understanding resistance to epidermal growth factor receptor inhibitors.
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Academic Article
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Molecular phenotype predicts sensitivity of squamous cell carcinoma of the head and neck to epidermal growth factor receptor inhibition.
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Academic Article
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Novel targeted therapies in head and neck cancer.
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Academic Article
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The role of chemotherapy in locally advanced head and neck squamous cell carcinoma.
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Academic Article
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The future of induction chemotherapy for head and neck squamous cell carcinoma.
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Academic Article
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Multidisciplinary care of the patient with head and neck cancer.
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Academic Article
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Epidermal growth factor receptor directed therapy in head and neck cancer.
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Academic Article
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Role of epidermal growth factor receptor pathway-targeted therapy in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck.
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Academic Article
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Phase III study of gefitinib compared with intravenous methotrexate for recurrent squamous cell carcinoma of the head and neck [corrected].
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Academic Article
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Modifiable risk behaviors in patients with head and neck cancer.
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Academic Article
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Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas.
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Academic Article
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Rare occurrence of EGFRvIII deletion in head and neck squamous cell carcinoma.
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Academic Article
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Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes.
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Academic Article
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DNA repair biomarkers XPF and phospho-MAPKAP kinase 2 correlate with clinical outcome in advanced head and neck cancer.
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Academic Article
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Comparison of outcomes of locoregionally advanced oropharyngeal and non-oropharyngeal squamous cell carcinoma over two decades.
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Academic Article
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Race and competing mortality in advanced head and neck cancer.
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Academic Article
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Phase III randomized trial of induction chemotherapy in patients with N2 or N3 locally advanced head and neck cancer.
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Academic Article
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Aspiration pneumonia after concurrent chemoradiotherapy for head and neck cancer.
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Academic Article
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Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss.
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Academic Article
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Targeting the PI3K/AKT/mTOR pathway in squamous cell carcinoma of the head and neck.
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Academic Article
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Combined TP53 mutation/3p loss correlates with decreased radiosensitivity and increased matrix-metalloproteinase activity in head and neck carcinoma.
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Academic Article
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Afatinib versus placebo as adjuvant therapy after chemoradiation in a double-blind, phase III study (LUX-Head & Neck 2) in patients with primary unresected, clinically intermediate-to-high-risk head and neck cancer: study protocol for a randomized controlled trial.
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Academic Article
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Study of functional infrared imaging for early detection of mucositis in locally advanced head and neck cancer treated with chemoradiotherapy.
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Academic Article
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Open Access in biomedical sciences: what the current turning point means more specifically to Oral Oncology contributors and readers.
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Academic Article
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Reply to s. Chakraborty et al.
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Academic Article
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Mechanisms of and therapeutic approaches for overcoming resistance to epidermal growth factor receptor (EGFR)-targeted therapy in squamous cell carcinoma of the head and neck (SCCHN).
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Academic Article
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Ex vivo antibody-dependent cellular cytotoxicity inducibility predicts efficacy of cetuximab.
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Academic Article
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Afatinib versus methotrexate as second-line treatment in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck progressing on or after platinum-based therapy (LUX-Head & Neck 1): an open-label, randomised phase 3 trial.
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Academic Article
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An open-label single-arm, phase II trial of zalutumumab, a human monoclonal anti-EGFR antibody, in patients with platinum-refractory squamous cell carcinoma of the head and neck.
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Academic Article
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A randomized, phase II study of afatinib versus cetuximab in metastatic or recurrent squamous cell carcinoma of the head and neck.
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Academic Article
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Rationale and design of LUX-Head & Neck 1: a randomised, Phase III trial of afatinib versus methotrexate in patients with recurrent and/or metastatic head and neck squamous cell carcinoma who progressed after platinum-based therapy.
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Academic Article
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Towards a personalized treatment of head and neck cancer.
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Academic Article
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Current Treatment Options for Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma.
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Academic Article
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Afatinib efficacy against squamous cell carcinoma of the head and neck cell lines in vitro and in vivo.
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Academic Article
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Importance of Radiation Oncologist Experience Among Patients With Head-and-Neck Cancer Treated With Intensity-Modulated Radiation Therapy.
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Academic Article
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A Novel Peptide for Simultaneously Enhanced Treatment of Head and Neck Cancer and Mitigation of Oral Mucositis.
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Academic Article
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Response-adapted volume de-escalation (RAVD) in locally advanced head and neck cancer.
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Academic Article
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American Cancer Society Head and Neck Cancer Survivorship Care Guideline.
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Academic Article
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Considering the survivorship care needs of head and neck cancer survivors.
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Academic Article
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Afatinib versus methotrexate in older patients with second-line recurrent and/or metastatic head and neck squamous cell carcinoma: subgroup analysis of the LUX-Head & Neck 1 trial.
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Academic Article
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Final Results of a Randomized Phase 2 Trial Investigating the Addition of Cetuximab to Induction Chemotherapy and Accelerated or Hyperfractionated Chemoradiation for Locoregionally Advanced Head and Neck Cancer.
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Academic Article
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A phase I dose escalation study of Ad GV.EGR.TNF.11D (TNFerade) with concurrent chemoradiotherapy in patients with recurrent head and neck cancer (HNC).
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Academic Article
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Use of systematic analysis of DNA repair pathways in head and neck cancer (HNC) to identify XPF as a novel predictor of induction response, and pMK2 relationship to chemoradiotherapy.
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Academic Article
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Integration of gefitinib (G), into a concurrent chemoradiation (CRT) regimen followed by G adjuvant therapy in patients with locally advanced head and neck cancer (HNC) - a Phase II Trial.
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Academic Article
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Immunotherapy of head and neck cancer: Emerging clinical trials from a National Cancer Institute Head and Neck Cancer Steering Committee Planning Meeting.
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Academic Article
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Phase II trial pemetrexed-based induction chemotherapy followed by concomitant chemoradiotherapy in previously irradiated head and neck cancer patients.
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Academic Article
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Pembrolizumab versus methotrexate, docetaxel, or cetuximab for recurrent or metastatic head-and-neck squamous cell carcinoma (KEYNOTE-040): a randomised, open-label, phase 3 study.
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Academic Article
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Induction chemotherapy in locally advanced squamous cell carcinoma of the head and neck: role, controversy, and future directions.
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Academic Article
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Randomized phase II trial of cixutumumab alone or with cetuximab for refractory recurrent/metastatic head and neck squamous cell carcinoma.
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Academic Article
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Serum antibodies open the door to prediction and prognostication in human papillomavirus-related head and neck cancer.
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Academic Article
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Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer.
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Academic Article
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Biomarkers predict enhanced clinical outcomes with afatinib versus methotrexate in patients with second-line recurrent and/or metastatic head and neck cancer.
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Academic Article
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Prognostic Role of p16 in Nonoropharyngeal Head and Neck Cancer.
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Academic Article
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A phase I open-label dose-escalation study of the anti-HER3 monoclonal antibody LJM716 in patients with advanced squamous cell carcinoma of the esophagus or head and neck and HER2-overexpressing breast or gastric cancer.
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Academic Article
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Immune Modulation of Head and Neck Squamous Cell Carcinoma and the Tumor Microenvironment by Conventional Therapeutics.
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Academic Article
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The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC).
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Academic Article
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Afatinib as second-line treatment in patients with recurrent/metastatic squamous cell carcinoma of the head and neck: Subgroup analyses of treatment adherence, safety and mode of afatinib administration in the LUX-Head and Neck 1 trial.
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Academic Article
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Afatinib versus methotrexate as second-line treatment in Asian patients with recurrent or metastatic squamous cell carcinoma of the head and neck progressing on or after platinum-based therapy (LUX-Head & Neck 3): an open-label, randomised phase III trial.
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Academic Article
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Selection of Head and Neck Cancer Patients for Intensive Therapy.
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Academic Article
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HPV16 E5 Mediates Resistance to PD-L1 Blockade and Can Be Targeted with Rimantadine in Head and Neck Cancer.
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Academic Article
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Cost-effectiveness analysis of nivolumab for the treatment of squamous cell carcinoma of the head and neck in the United States.
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Academic Article
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Comparing programmed death ligand 1 scores for predicting pembrolizumab efficacy in head and neck cancer.
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Academic Article
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Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC Group.
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Academic Article
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Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer.
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Academic Article
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Defining the Role of Immunotherapy in the Curative Treatment of Locoregionally Advanced Head and Neck Cancer: Promises, Challenges, and Opportunities.
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Academic Article
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Inevitable Progress-Relying on the Immune System, Not Chance.
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Academic Article
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Safety and Efficacy of Pembrolizumab in Combination with Acalabrutinib in Advanced Head and Neck Squamous Cell Carcinoma: Phase 2 Proof-of-Concept Study.
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Academic Article
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Intralesional SD-101 in Combination with Pembrolizumab in Anti-PD-1 Treatment-Naïve Head and Neck Squamous Cell Carcinoma: Results from a Multicenter, Phase II Trial.
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Academic Article
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Next generation sequencing of cell free circulating tumor DNA in blood samples of recurrent and metastatic head and neck cancer patients.
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Academic Article
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Hereditary oral squamous cell carcinoma associated with CDKN2A germline mutation: a case report.
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Academic Article
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Xevinapant or placebo plus chemoradiotherapy in locally advanced squamous cell carcinoma of the head and neck: TrilynX phase III study design.
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Academic Article
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Role of Induction Chemotherapy Prior to Chemoradiation in Head and Neck Squamous Cell Cancer-Systematic Review and Meta-analysis.
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Academic Article
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Patient selection for immunotherapy in head and neck cancer - Authors' reply.
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Academic Article
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Somatic 9p24.1 alterations in HPV- head and neck squamous cancer dictate immune microenvironment and anti-PD-1 checkpoint inhibitor activity.
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Academic Article
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A Randomized Multi-institutional Phase II Trial of Everolimus as Adjuvant Therapy in Patients with Locally Advanced Squamous Cell Cancer of the Head and Neck.
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Academic Article
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A phase I study of avelumab, palbociclib, and cetuximab in patients with recurrent or metastatic head and neck squamous cell carcinoma.
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Grant
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Clinical translation of 19F MRI to visualize cancer immunotherapeutic cells
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Grant
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Functional Infrared Imaging Predicts Radiation Mucositis
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Academic Article
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Method for estimation of apoptotic cell fraction of cytotherapy using in vivo fluorine-19 magnetic resonance: pilot study in a patient with head and neck carcinoma receiving tumor-infiltrating lymphocytes labeled with perfluorocarbon nanoemulsion.
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Academic Article
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Pan-Cancer Analysis of Patient Tumor Single-Cell Transcriptomes Identifies Promising Selective and Safe Chimeric Antigen Receptor Targets in Head and Neck Cancer.
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